Prof. Sean Fair

Abril-Parreño L.;Carthy T.R.;Keogh K.;Stiavnická M.;O'Meara C.;Lonergan P.;Kenny D.A.;Fair S. (2023) Genome-wide association study reveals candidate markers related to field fertility and semen quality traits in Holstein-Friesian bulls. Animal

Coen S.;Keogh K.;Lonergan P.;Fair S.;Kenny D.A. (2023) Early life nutrition affects the molecular ontogeny of testicular development in the young bull calf. Scientific Reports

Stiavnicka, M, Hosek P, Abril-Parreno L, Kenny DA, Lonergan P, Fair S (2023) Membrane remodulation and hyperactivation are impaired in frozen- thawed sperm of low-fertility bulls. NEW YORK Theriogenology :115-121

Rabaglino MB, Le Danvic C, Schibler L, Kupisiewicz K., Perrier JP, O'Meara CM, Kenny DA, Fair S, Lonergan P (2022) Identification of sperm proteins as biomarkers of field fertility in Holstein-Friesian bulls used for artificial insemination. Journal Of Dairy Science

Abril-Parreño L, Morgan J, Krogenæs A, Druart X, Cormican P, Gallagher ME, Reid C, Meade K, Saldova R, Fair S (2022) Biochemical and molecular characterization of sialylated cervical mucins in sheep¿. Biology Of Reproduction :419-431

Griffin R.A.;Swegen A.;Baker M.A.;Ogle R.A.;Smith N.;Aitken R.J.;Skerrett-Byrne D.A.;Fair S.;Gibb Z. (2022) Proteomic analysis of spermatozoa reveals caseins play a pivotal role in preventing short-term periods of subfertility in stallions. Biology Of Reproduction :741-755

O'Callaghan E, Sánchez JM, Rabaglino MB, McDonald M, Liu H, Spencer TE, Fair S, Kenny DA, Lonergan P (2022) Influence of sire fertility status on conceptus-induced transcriptomic response of the bovine endometrium. Frontiers In Cell And Developmental Biology

Abril-Parreño L.;Meade K.G.;Krogenæs A.K.;Druart X.;Cormican P.;Fair S. (2022) Ewe breed differences in the cervical transcriptome at the follicular phase of a synchronised oestrous cycle. Bmc Genomics

Abril-Parreño L.;Wilkinson H.;Krogenæs A.;Morgan J.;Gallagher M.E.;Reid C.;Druart X.;Fair S.;Saldova R. (2022) Identification and characterization of O-linked glycans in cervical mucus as biomarkers of sperm transport: A novel sheep model. Glycobiology :23-35

Donnellan E.M.;Lonergan P.;Meade K.G.;Fair S. (2022) An ex-vivo assessment of differential sperm transport in the female reproductive tract between high and low fertility bulls. Theriogenology :42-49

Stiavnická M, Chaulot-Talmon A, Perrier J.P, Hosek P, Kenny D.A, Lonergan P, Kiefer H, Fair S. (2022) Sperm DNA methylation patterns at discrete CpGs and genes involved in embryonic development are related to bull fertility. Bmc Genomics

Abril-Parreno L, Krogenaes AK, Druart X, Cormican, P, Fair S, Meade KG (2022) Cervical immune activation during the luteal phase may compromise subsequent trans-cervical ram sperm transport. CARY Biology Of Reproduction :967-976

Taaffe P, O'Meara CM, Stiavnicka M, Byrne CJ, Eivers B, Lonergan P, Fair S (2022) Increasing the frequency of ejaculate collection in young dairy bulls increases semen production and field fertility. Theriogenology :45-52

Donnellan EM, Perrier JP, Keogh K, Stiavnická M, Collins CM, Dunleavy EM, Sellem E, Bernecic NC, Lonergan P, Kenny DA., Fair S (2022) Identification of differentially expressed mRNAs and miRNAs in spermatozoa of bulls of varying fertility. Frontiers In Veterinary Science

Bernecic, NC;Donnellan, E;O'Callaghan, E;Kupisiewicz, K;O'Meara, C;Weldon, K;Lonergan, P;Kenny, DA;Fair, S (2021) Comprehensive functional analysis reveals that acrosome integrity and viability are key variables distinguishing artificial insemination bulls of varying fertility. NEW YORK : ELSEVIER SCIENCE INC Journal Of Dairy Science :11226-11241

O'Callaghan, E;Sanchez, JM;McDonald, M;Kelly, AK;Hamdi, M;Maicas, C;Fair, S;Kenny, DA;Lonergan, P (2021) Sire contribution to fertilization failure and early embryo survival in cattle. NEW YORK : ELSEVIER SCIENCE INC Journal Of Dairy Science :7262-7271

Morgan-Davies, C;Kyle, J;Boman, IA;Wishart, H;McLaren, A;Fair, S;Creighton, P (2021) A comparison of farm labour, profitability, and carbon footprint of different management strategies in Northern European grassland sheep systems. OXFORD : ELSEVIER SCI LTD Agricultural Systems

Abril-Parreño L;Krogenæs AK;Byrne CJ;Donovan A;Stuen S;Caldas E;Diskin M;Druart X;Fair S; (2021) Ewe breed differences in cervical anatomy and cervicovaginal mucus properties: An international study.. Theriogenology

Abril-Parreno, L;Meade, KG;Krogenaes, AK;Druart, X;Fair, S;Cormican, P (2021) Conserved and breed-specific differences in the cervical transcriptome of sheep with divergent fertility at the follicular phase of a natural oestrus cycle. LONDON : BMC Bmc Genomics

Donnellan, EM;O'Brien, MB;Meade, KG;Fair, S (2021) Comparison of the uterine inflammatory response to frozen-thawed sperm from high and low fertility bulls. NEW YORK : ELSEVIER SCIENCE INC Theriogenology :26-34

O'Callaghan E.;Sánchez J.M.;Rabaglino M.B.;McDonald M.;Liu H.;Spencer T.E.;Fair S.;Kenny D.A.;Lonergan P. (2021) 118 Influence of sire fertility status on conceptus-induced transcriptomic response of the bovine endometrium. Reproduction Fertility And Development :-296

Romero-Aguirregomezcorta, J;Laguna-Barraza, R;Fernandez-Gonzalez, R;Stiavnicka, M;Ward, F;Cloherty, J;McAuliffe, D;Larsen, PB;Grabrucker, AM;Gutierrez-Adan, A;Newport, D;Fair, S (2021) Sperm selection by rheotaxis improves sperm quality and early embryo development. BRISTOL : BIOSCIENTIFICA LTD Reproduction :343-352

Byrne, CJ;Fair, S;Dick, JR;Lonergan, P;Kenny, DA (2021) Dietary supplementation with fish oil and safflower oil, during the finishing period, alters brisket muscle fatty acid profile and n-6/n-3 ratio but not carcass traits of dairy beef bulls. NEW YORK : ELSEVIER SCIENCE INC Applied Animal Science :436-444

Coen, SP;Keogh, K;Byrne, CJ;Lonergan, P;Fair, S;Crowe, MA;Kenny, DA (2021) Effect of plane of nutrition during the first 12 weeks of life on growth, metabolic and reproductive hormone concentrations, and testicular relative mRNA abundance in preweaned Holstein Friesian bull calves. CARY : OXFORD UNIV PRESS INC Animal Science Journal

Johnson, GP;Fair, S;Hoey, DA (2021) Primary cilium-mediated MSC mechanotransduction is dependent on Gpr161 regulation of hedgehog signalling. NEW YORK : ELSEVIER SCIENCE INC Bone

Perrier J.P.;Kenny D.A.;Chaulot-Talmon A.;Byrne C.J.;Sellem E.;Jouneau L.;Aubert-Frambourg A.;Schibler L.;Jammes H.;Lonergan P.;Fair S.;Kiefer H. (2020) Accelerating Onset of Puberty Through Modification of Early Life Nutrition Induces Modest but Persistent Changes in Bull Sperm DNA Methylation Profiles Post-puberty. Frontiers In Genetics

Richardson, L;Hanrahan, JP;Tharmalingam, T;Carrington, SD;Lonergan, P;Evans, ACO;Fair, S (2019) Cervical mucus sialic acid content determines the ability of frozen-thawed ram sperm to migrate through the cervix. BRISTOL : BIOSCIENTIFICA LTD Reproduction :259-271

O'Brien A.;Purfield D.;Judge M.;Long C.;Fair S.;Berry D. (2019) Population structure and breed composition prediction in a multi-breed sheep population using genome-wide single nucleotide polymorphism genotypes. Animal

Romero-Aguirregomezcorta J.;Cronin S.;Donnellan E.;Fair S. (2019) Progesterone induces the release of bull spermatozoa from oviductal epithelial cells. Reproduction Fertility And Development

O'Brien A.;Judge M.;Fair S.;Berry D. (2019) High imputation accuracy from informative low-to-medium density single nucleotide polymorphism genotypes is achievable in sheep. Animal Science Journal :1550-1567

Silva, DM;Holden, SA;de Souza, JC;Fair, S (2019) In vitro addition of DHA and IGF-I increases the progressive motility of cryopreserved stallion semen. POUSO ALEGRE : INST FEDERAL SUL MINAS GERAIS-I FSULDEMINAS Revista Agrogeoambiental :127-138

Anand-Ivell R.;Byrne C.;Arnecke J.;Fair S.;Lonergan P.;Kenny D.;Ivell R. (2019) Prepubertal nutrition alters Leydig cell functional capacity and timing of puberty. Plos One

English, AM;Waters, SM;Cormican, P;Byrne, CJ;Fair, S;Kenny, DA (2018) Effect of early calf-hood nutrition on the transcriptomic profile of subcutaneous adipose tissue in Holstein-Friesian bulls. LONDON : BIOMED CENTRAL LTD Bmc Genomics

Byrne, CJ;Fair, S;English, AM;Urh, C;Sauerwein, H;Crowe, MA;Lonergan, P;Kenny, DA (2018) Plane of nutrition before and after 6 months of age in Holstein-Friesian bulls: II. Effects on metabolic and reproductive endocrinology and identification of physiological markers of puberty and sexual maturation. NEW YORK : ELSEVIER SCIENCE INC Journal Of Dairy Science :3460-3475

Byrne, CJ;Fair, S;English, AM;Cirot, M;Staub, C;Lonergan, P;Kenny, DA (2018) Plane of nutrition before and after 6 months of age in Holstein-Friesian bulls: I. Effects on performance, body composition, age at puberty, and postpubertal semen production. NEW YORK : ELSEVIER SCIENCE INC Journal Of Dairy Science :3447-3459

Fernandez-Fuertes, B;Blanco-Fernandez, A;Reid, CJ;Meade, KG;Fair, S;Lonergan, P (2018) Removal of sialic acid from bull sperm decreases motility and mucus penetration ability but increases zona pellucida binding and polyspermic penetration in vitro. BRISTOL : BIOSCIENTIFICA LTD Reproduction :481-492

Murphy, EM;O'Meara, C;Eivers, B;Lonergan, P;Fair, S (2018) Optimizing storage temperature of liquid bovine semen diluted in INRA96. NEW YORK : ELSEVIER SCIENCE INC Journal Of Dairy Science :5549-5558

English, AM;Byrne, CJ;Cormican, P;Waters, SM;Fair, S;Kenny, DA (2018) Effect of Early Calf-Hood Nutrition on the Transcriptional Regulation of the Hypothalamic-Pituitary-Testicular axis in Holstein-Friesian Bull Calves. LONDON : NATURE PUBLISHING GROUP Scientific Reports

English, AM;Kenny, DA;Byrne, CJ;Sauerwein, H;Urh, C;Crowe, MA;Staub, C;Waters, SM;Fair, S (2018) Role of early life nutrition on regulating the hypothalamic-anterior pituitary-testicular axis of the bull. BRISTOL : BIOSCIENTIFICA LTD Reproduction :283-297

Murphy, EM,Eivers, B,O'Meara, CM,Lonergan, P,Fair, S (2018) Effect of increasing equilibration time of diluted bull semen up to 72 h prior to freezing on sperm quality parameters and calving rate following artificial insemination. Theriogenology :217-222

Romero-Aguirregomezcorta, J;Sugrue, E;Martinez-Fresneda, L;Newport, D;Fair, S (2018) Hyperactivated stallion spermatozoa fail to exhibit a rheotaxis-like behaviour, unlike other species. LONDON : NATURE PUBLISHING GROUP Scientific Reports

Murphy, EM,Eivers, B,O'Meara, CM,Lonergan, P,Fair, S (2018) Effect of storage temperature, nitrogen gassing and sperm concentration on the in vitro semen quality and in vivo fertility of liquid bull semen stored in INRA96. Theriogenology :223-228

Lyons, A;Narciandi, F;Donnellan, E;Romero-Aguirregomezcorta, J;O'Farrelly, C;Lonergan, P;Meade, KG;Fair, S (2018) Recombinant beta-defensin 126 promotes bull sperm binding t o bovine oviductal epithelia. CLAYTON : CSIRO PUBLISHING Reproduction Fertility And Development :1472-1481

Johnson, GP;Stavenschi, E;Eichholz, KF;Corrigan, MA;Fair, S;Hoey, DA (2018) Mesenchymal stem cell mechanotransduction is cAMP dependent and regulated by adenylyl cyclase 6 and the primary cilium. CAMBRIDGE : COMPANY BIOLOGISTS LTD Journal Of Cell Science

Murphy, EM;Kelly, AK;O'Meara, C;Eivers, B;Lonergan, P;Fair, S (2018) Influence of bull age, ejaculate number, and season of collection on semen production and sperm motility parameters in Holstein Friesian bulls in a commercial artificial insemination centre. CARY : OXFORD UNIV PRESS INC Animal Science Journal :2408-2418

Murphy, EM,O'Meara, C,Eivers, B,Lonergan, P,Fair, S (2018) Comparison of plant- and egg yolk-based semen diluents on in vitro sperm kinematics and in vivo fertility of frozen-thawed bull semen. Animal Reproduction Science :70-75

Hall, TJ,McQuillan, C,Finlay, EK,O'Farrelly, C,Fair, S,Meade, KG (2017) Comparative genomic identification and validation of beta-defensin genes in the Ovis aries genome. Bmc Genomics

Byrne, CJ,Fair, S,English, AM,Johnston, D,Lonergan, P,Kenny, DA (2017) Effect of milk replacer and concentrate intake on growth rate, feeding behaviour and systemic metabolite concentrations of pre-weaned bull calves of two dairy breeds. Animal :1531-1538

Murphy, EM,Murphy, C,O'Meara, C,Dunne, G,Eivers, B,Lonergan, P,Fair, S (2017) A comparison of semen diluents on the in vitro and in vivo fertility of liquid bull semen. Journal Of Dairy Science :1541-1554

O'Brien, AC,McHugh, N,Wall, E,Pabiou, T,McDermott, K,Randles, S,Fair, S,Berry, DP (2017) Genetic parameters for lameness, mastitis and dagginess in a multi-breed sheep population. Animal :911-919

Whiston, R,Finlay, EK,McCabe, MS,Cormican, P,Flynn, P,Cromie, A,Hansen, PJ,Lyons, A,Fair, S,Lonergan, P,O' Farrelly, C,Meade, KG (2017) A dual targeted beta-defensin and exome sequencing approach to identify, validate and functionally characterise genes associated with bull fertility. Scientific Reports

Byrne, CJ,Fair, S,English, AM,Urh, C,Sauerwein, H,Crowe, MA,Lonergan, P,Kenny, DA (2017) Effect of breed, plane of nutrition and age on growth, scrotal development, metabolite concentrations and on systemic gonadotropin and testosterone concentrations following a GnRH challenge in young dairy bulls. Theriogenology :58-68

Holden, SA,Fernandez-Fuertes, B,Murphy, EM,Lonergan, P,Fair, S (2017) Effect of seminal plasma from high- and low-fertility bulls on cauda epididymal sperm function. Reproduction Fertility And Development :2457-2465

Murphy, EM,Stanton, C,O'Brien, C,Murphy, C,Holden, S,Murphy, RP,Varley, P,Boland, MP,Fair, S (2017) The effect of dietary supplementation of algae rich in docosahexaenoic acid on boar fertility. Theriogenology :78-87

Johnson, GP,English, AM,Cronin, S,Hoey, DA,Meade, KG,Fair, S (2017) Genomic identification, expression profiling, and functional characterization of CatSper channels in the bovine. Biology Of Reproduction :302-312

Silva, DM,Holden, SA,Lyons, A,Souza, JC,Fair, S (2017) In vitro addition of docosahexaenoic acid improves the quality of cooled but not frozen-thawed stallion semen. Reproduction Fertility And Development :2021-2027

Byrne, CJ,Fair, S,English, AM,Holden, SA,Dick, JR,Lonergan, P,Kenny, DA (2017) Dietary polyunsaturated fatty acid supplementation of young post-pubertal dairy bulls alters the fatty acid composition of seminal plasma and spermatozoa but has no effect on semen volume or sperm quality. Theriogenology :289-300

Holden, SA,Murphy, C,Moreno, JF,Butler, ST,Cromie, AR,Lonergan, P,Fair, S (2017) In vitro characterisation of fresh and frozen sex-sorted bull spermatozoa. Reproduction Fertility And Development :1415-1425

Holden, SA,Fernandez-Fuertes, B,Murphy, C,Whelan, H,O'Gorman, A,Brennan, L,Butler, ST,Lonergan, P,Fair, S (2017) Relationship between in vitro sperm functional assessments, seminal plasma composition, and field fertility after AI with either non-sorted or sex-sorted bull semen. Theriogenology :221-228

DM Silva, SA Holden, A Lyons, JC Souza, S Fair (2017) The in vitro addition of docosahexaenoic acid (DHA) improves the quality of cooled but not frozen-thawed stallion semen. Reproduction Fertility And Development

Johnson, GP,Lloyd, AT,O'Farrelly, C,Meade, KG,Fair, S (2016) Comparative genomic identification and expression profiling of a novel -defensin gene cluster in the equine reproductive tract. Reproduction Fertility And Development :1499-1508

Murphy, C,Holden, SA,Murphy, EM,Cromie, AR,Lonergan, P,Fair, S (2016) The impact of storage temperature and sperm number on the fertility of liquid-stored bull semen. Reproduction Fertility And Development :1349-1359

Narciandi, F,Fernandez-Fuertes, B,Khairulzaman, I,Jahns, H,King, D,Finlay, EK,Mok, KH,Fair, S,Lonergan, P,Farrelly, CO,Meade, KG (2016) Sperm-Coating Beta-Defensin 126 Is a Dissociation-Resistant Dimer Produced by Epididymal Epithelium in the Bovine Reproductive Tract. Biology Of Reproduction

Fernandez-Fuertes, B,Narciandi, F,O'Farrelly, C,Kelly, AK,Fair, S,Meade, KG,Lonergan, P (2016) Cauda Epididymis-Specific Beta-Defensin 126 Promotes Sperm Motility but Not Fertilizing Ability in Cattle. Biology Of Reproduction

McGovern F.;Campion F.;Sweeney T.;Fair S.;Lott S.;Boland T. (2015) Altering ewe nutrition in late gestation: II. The impact on fetal development and offspring performance. Animal Science Journal :4873-4882

McGovern, FM,Campion, FP,Sweeney, T,Fair, S,Lott, S,Boland, TM (2015) Altering ewe nutrition in late gestation: II. The impact on fetal development and offspring performance. Journal Of Animal Science :4873-4882

Fair, S,Doyle, DN,Diskin, MG,Hennessy, AA,Kenny, DA (2014) The effect of dietary n-3 polyunsaturated fatty acids supplementation of rams on semen quality and subsequent quality of liquid stored semen. Theriogenology :210-219

Murphy, C,English, AM,Holden, SA,Fair, S (2014) Cholesterol-loaded-cyclodextrins improve the post-thaw quality of stallion sperm. Animal Reproduction Science :123-129

Murphy C.;Fahey A.;Shafat A.;Fair S. (2013) Reducing sperm concentration is critical to limiting the oxidative stress challenge in liquid bull semen. Journal Of Dairy Science :4447-4454

Kiernan, M,Fahey, AG,Fair, S (2013) The effect of the in vitro supplementation of exogenous long-chain fatty acids on bovine sperm cell function. Reproduction Fertility And Development :947-954

Murphy, C,Fahey, AG,Shafat, A,Fair, S (2013) Reducing sperm concentration is critical to limiting the oxidative stress challenge in liquid bull semen. Journal Of Dairy Science :4447-4454

Richardson, L,Hanrahan, JP,Donovan, A,Marti, JI,Fair, S,Evans, ACO,Lonergan, P (2012) Effect of site of deposition on the fertility of sheep inseminated with frozen-thawed semen. Animal Reproduction Science :160-164

Fahey A.;Duffy P.;Fair S. (2012) Effect of exposing rams to a female stimulus before semen collection on ram libido and semen quality. Animal Science Journal :3451-3456

Fahey, AG,Duffy, P,Fair, S (2012) Effect of exposing rams to a female stimulus before semen collection on ram libido and semen quality. Journal Of Animal Science :3451-3456

Richardson, L; Hanrahan, JP; O'Hara, L; Donovan, A; Fair, S; O'Sullivan, M; Carrington, SD; Lonergan, P; Evans, ACO (2011) Ewe breed differences in fertility after cervical AI with frozen-thawed semen and associated differences in sperm penetration and physicochemical properties of cervical mucus. Animal Reproduction Science :37-43

Al Naib, A; Hanrahan, JP; Lonergan, P; Fair, S (2011) In vitro assessment of sperm from bulls of high and low field fertility. Theriogenology :161-167

O'Hara L, Hanrahan JP, Richardson L, Donovan A, Fair S, Evans AC, Lonergan P (2010) Effect of storage duration, storage temperature, and diluent on the viability and fertility of fresh ram sperm.. Theriogenology :541-549

O' Meara CM, Hanrahan JP, Prathalingam NS, Owen JS, Donovan A, Fair S, Ward F, Wade M, Evans AC, Lonergan P (2008) Relationship between in vitro sperm functional tests and in vivo fertility of rams following cervical artificial insemination of ewes with frozen-thawed semen.. Theriogenology :513-522

Garcia-Garcia RM, Ward F, Fair S, O'Meara CM, Wade M, Duffy P, Lonergan P (2007) Development and quality of sheep embryos cultured in commercial G1.3/G2.3 sequential media.. Animal Reproduction Science :233-240

Fair S, Hanrahan JP, Donovan A, Duffy P, O'Meara CM, Lonergan P, Evans AC (2007) Hormonal relationships during the periovulatory period among ewe breeds known to differ in fertility after cervical artificial insemination with frozen thawed semen.. Animal Reproduction Science :284-294

O'Meara CM, Donovan A, Hanrahan JP, Duffy P, Fair S, Evans AC, Lonergan P (2007) Resuspending ram spermatozoa in seminal plasma after cryopreservation does not improve pregnancy rate in cervically inseminated ewes.. Theriogenology :1262-1268

Fair S, Hanrahan JP, Ward F, O'Meara CM, Duffy P, Donovan A, Lonergan P, Evans AC (2006) The difference in embryo quality between Belclare and Suffolk ewes is not due to differences in oocyte quality.. Theriogenology :191-197

Fair S, Hanrahan JP, O'Meara CM, Duffy P, Rizos D, Wade M, Donovan A, Boland MP, Lonergan P, Evans AC (2005) Differences between Belclare and Suffolk ewes in fertilization rate, embryo quality and accessory sperm number after cervical or laparoscopic artificial insemination.. Theriogenology :1995-2005

O'Meara CM, Hanrahan JP, Donovan A, Fair S, Rizos D, Wade M, Boland MP, Evans AC, Lonergan P (2005) Relationship between in vitro fertilisation of ewe oocytes and the fertility of ewes following cervical artificial insemination with frozen-thawed ram semen.. Theriogenology :1797-1808