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Prof. Philip Jakeman

Biography

Short Biography Philip Jakeman, graduated with an honours degree and research Masters Degree in Biochemistry from the University of Manchester, UK. A C.A.S.E. research scholarship in collaboration Astra Zeneca was followed by a PhD within the Human Performance Unit of the University of Salford working as a biochemist supporting the physiological development of elite young athletes. Further human endocrine and metabolic studies of exercise in normal and clinical populations formed the basis of a PhD thesis under the supervision of Professor L.S. Bark, Vice-President of the Royal Society of Chemistry. Post-doctoral work, funded by Nicolas International, utilised radio-labelled drug diffusion techniques to optimise topical drug delivery through human skin. Appointed to the Department of Sport and Exercise Sciences, University of Birmingham in 1989, Dr Jakeman's collaborative work with the University's Clinical Research Unit (QEMC) under the direction of Professor Martin Kendal contributed to a strong research base (HEFC rated 5* in 1996) specialising in human metabolism, pharmacological/exercise interaction and the biochemistry of exercise. Appointment as Professor of Exercise Science in 1995, Dr Jakeman moved permanently to UL in 1996 as Head of the Department of Physical Education and Sport Sciences with a responsibility to develop high quality teaching and scientific research in exercise metabolism. Released from the duties of H.O.D. Dr Jakeman is the lead PI of the Sports Nutrition and Healthy Ageing Pillar of the National Technolgy Centre, Food for Health Ireland (FHI). Funded by Programme and Innovation Partnership Grants (>€5m) with Enterprise Ireland the research group conduct basic and applied research in human metabolism specialising in the interaction between nutrient intake and physical activity.

Interests:

A keen sportsperson with junior representative honours in tennis and rugby, now enjoys the less demanding swing of a gold club. Passionate about sport, food, dogs and, of course, family. Has one son who also studied Biochemistry (Imperial College, London) before completing a DPhil in cancer immunology at Oxford and now CEO of the spin-out company Macrophox, cell-based therapy for cancer.

Teaching Interests

Human Physiology and Metabolism
Exercise Physiology
Physiological Limitations to High Performance Sport
Exercise Metabolism
Nutrient-exercise interaction in sport, ageing and metabolic diseases
Sports Nutrition
Peri-exercise nutrition for optimal training adaptation and sport performance


Professional Activities

Committee

  • 2012 Medical Research Council/Wellcome Trust UK Biobank Imaging Enhancement,
  • 2004 Programmatic Review Peer Group Panel, Department of Applied Biology and Chemistry, Carlow Institute of Technology,
  • 2002 Food Safety Promotion Board (FSPB) Expert Committee: Stimulant Drinks,
  • 1899 Leverhulme Trust (U.K.),
  • 1899 Medical Research Council (U.K.),
  • 1899 Wellcome Trust (U.K.),

Association

  • 2009 Professional Member, American College of Sports medicine
  • 2006 Fellow Council Member, Biomedical Sciences Section, Royal Academy of Medicine in Ireland
  • 2005 Professional Member Reviewer, European College of Sport sciences
  • 1984 Professional Member, Member Human Physiology Interest Group, Physiological Society
  • 1975 Member Council Member, Irish Section Local Ambassador (LA) to Biochemistry Society in Ireland, Biochemical Society

Education

  • 1984 University of Salford - Ph.D.
  • 1978 University of Manchester - MSc
  • 1975 University of Salford - B.Sc.

Employment

  • 1981 University of Salford, Manchester, UK - Reserach Fellow

Consultancy

  • - Member, Glanbia Scientfic Advisory Group. Advisory body to Glanbia Nutritionals
  • - Member, Scientific Advisory Group, Glanbia Nutritionals

Publications

Book

Book Chapter

1991

Laboratory Procedures for Physiological Measurement
Jakeman PM
Physiological Assessment of the Elite Athlete

1982

Factors affecting athletic performance
Jakeman, PM
Science and Sporting Performance: Management or manipulation?

Conference Contribution

2006

The Biology of Exercise
Royal Academy of Medicine in Ireland (RAMI) Biomedical Sciences

2001

Symposium: Exercise: Benefits and Limitations
Royal Academy of Medicine in Ireland (RAMI) Biomedical Sciences

Conference Publication

2015

Active Healthy Aging Sports Science and Neuroscience Conference
Francis, P., Mc Cormack, W., Lyons M. and Jakeman P.

2015

University Hospital Limerick Research Symposium, 9th Oct 2015, Limerick.
Jakeman, P., Dowling, L., Skelly, M., Dunne, C.P.

2015

Physiological Society Topic Meeting - 'Ageing and Degeneration: A Physiological Perspective'
Francis, P., Toomey, C., McCormack, W., Lyons, M. and Jakeman, P.

2015

BSRA Annual Scientific Meeting
Francis, P., Mc Cormack, W., Toomey, C., Norton, C., Saunders, J., Kerrins, E., Lyons M. & Jakeman, P.

2013
2013

The Institute of Physical Therapy & Applied Science Annual Conference
Francis, P., Mc Cormack, W., Lyons, M. and Jakeman, P.

2009

CAPE Forum
Walsh, C., Jakeman, P., O¿Regan, B. and Moles, R.

2006

European Neurological Society
S. Hosback, P. Jakeman, C. Nolan, M. Doyle, O. O' Toole, G. Gorman, C. Lynch, O. Hardiman

2006

BioSciences Meeting, Royal Academy of Medicine in Ireland
Power O, Hunter A, Rainsford G, Jakeman P

2006

Annaul Meeting European College of Sports Science
Howard K, Miller O, Dowling I, Hunter A, Jakeman P

2006

Biomedical Sciences Meeting, Royal Academy of Medicine in Ireland
Hosback S, Hardiman O, Nolan CM, Doyle M, Gorman G, Lynch C, O¿Toole O, Jakeman P.

2006

BioMedical Sciences Meeting, Royal Academy of Medicine in Ireland
McCormack W, Rainsford G, Daughton J, Power O, O¿ Neill C, Jakeman P

2005
2005

28th Annual Conference of the Association of Clinical Biochemists in Ireland
Carroll P, Jakeman PM, Barrett E, Murphy N, Donnelly R, McLoughlin M and Murphy M.

2005

2nd Annual Conference of the Faculty of Sport and Exercise Medicine
Howard K, Miller O, Dowling I, Hunter A, Jakeman P.

2005

Royal Academy of Medicine in Ireland, Biomedical Sciences Winter Meeting
Flanagan E, Foley M, Rossiter A and Jakeman PM.

2005

7th European Congress of Endocrinology
S. Keenehan, R Daniels, A Hunter, P. Jakeman.

2005

11th World Congress on the Menopause
Towler MR, Wren A, Jakeman PM and Cummins N.

2005

28th Annual Conference of the Association of Clinical Biochemists in Ireland
Carroll P, Hunter A, Barry D, Barrett E, Loughnane M, Donnelly R, Murphy N and Jakeman PM.

2003

13th Meeting of the European Neurological Society
O. O'Toole, S. Hosback, M. Doyle, C. Lynch, G. Gorman, J. Long, C. Nolan, P. Jakeman, O. Hardiman

2003

International Osteoporosis Meeting
Loughnane M, Murphy N, Donnelly R, Barrett E., Barry D, Jakeman PM, Carroll P

2002

6th Annual Congress of the European College of Sport Science
Carroll, P., Hunter A., Barry D., Barrett E. and Jakeman, P.M

2001
2001

International Sports Medicine Conference
Carroll P and Jakeman PM

2001
2001

International Sports Medicine Conference
Regan J, Donnelly A, Roper H, Jakeman PM

2001

Proceedings of the International Sports Medicine Conference
Regan J, Donnelly A, Roper H and Jakeman PM

2000

3rd Annual Research Day Biomedicine in the Aged
Murphy-Griffin M, Jakeman PM, Horgan JH

1997

10thInternational Symposium, Biochemistry of Exercise 1.57
Welsh LJ, Keegan MA, Mohebbi H, Campbell IT and Jakeman PM

1997

10thInternational Symposium, Biochemistry of Exercise 2.6
Jakeman PM, Greenhow S and Jones DA

1997

10thInternational Symposium, Biochemistry of Exercise 2.74
Whitehouse-Tedd P, Jakeman PM and Maxwell SRJ

1997

10thInternational Symposium, Biochemistry of Exercise 1.56
Welsh LJ, Regan J, Keogh R and Jakeman PM

1997

Royal Academy of Medicine in Ireland
Welsh LJ and Jakeman PM

1996

First Annual Congress of the European College of Sport Sciences
Jakeman PM, Jeal S, Cwyfan-Hughes S and Holly JMP

1995

An evaluation of the variability in prolactin secretion in response to the serotoninergic agonist d-fenfluramine in Man.
Greenhow, S; Jakeman, PM; Kendall, MJ; Dowling, BA; Franklin, M
Journal Of Physiology

1995

GASPAR: task specific image analysis software for use with human muscle histology.
Rivas, M; Skrone, J; Claridge, E; Jakeman, PM; Egginton, S
Journal Of Physiology

1995

Society for Experimental Biology A15.4
Egginton S and Jakeman PM

1995

Analysis of IGFBP-3 and protease activity during prolonged submaximal exercise to fatigue in Man.
Cwyfan Hughes, S; Jakeman, PM; Hopkins, NJ; Holly, JMP
Journal Of Endocrinology

1994

The role of IGF-I and its binding proteins in glucoregulation during exercise.
Hopkins, NJ; Jakeman, PM; Ferguson, R
Clinical Science

1994

Possible downregulation of 5-hydroxytryptamine activity in endurance trained athletes. Journal of Physiology
Jakeman, PM; Hawthorne, J; Holder, G; Kendall, MJ
Journal Of Physiology

1994

Scaling of muscle capillary supply in humans: effect of strength training.
Ahmed, S; Ross, H; Egginton, S; Mannion, AF; Jakeman, PM
Journal Of Physiology

1994

Proceedings of the 7th International Humic Substance Society Meeting.
Watt BE, Hayes TM, Jakeman PM and Hayes MHB

1994

Effect of antioxidant vitamin supplementation on muscle function after eccentric exercise.
Jakeman, PM; Maxwell, SRJ
International J. Sport Nutrition

Other Journal

2017

Muscle strength can better differentiate between gradations of functional performance than muscle quality in healthy 50 – 70y women.
37. Francis, P., Toomey, C., Mc Cormack, W., Lyons, M., & Jakeman, P.
The Brazilian Journal of Physical Therapy

2017

Voluntary contractile rate of torque development in healthy older women: Measurement of, association with functional tasks and response to intervention.
Francis, P., Mc Cormack, W., Lyons, M., & Jakeman, P.
Advances in Skeletal Muscle Function Assessment

2017

Age-group differences in the performance of selected tests of physical function and association with lower extremity strength.
Francis, P., Mc Cormack, W., Lyons, M., & Jakeman, P.
The Journal of Geriatric Physical Therapy

Other Publication

2015

A longitudinal study of body composition in elite male Gaelic Athletic Association (GAA) hurlers
Hughes, K,Davies, R,Toomey, C,McCormack, W,Cremona, A,O'Neill, C,Leahy, S,Francis, P,Jakeman, P
European Journal Of Clinical Nutrition

2015

The effects of hydration status on the measurement of lean tissue mass by Dual Energy X-Ray Absorptiometry
Cremona, A,Toomey, C,McCormack, W,Hurley, C,McLynn, R,Davies, R,Hughes, K,Jakeman, P
European Journal Of Clinical Nutrition

2015

Effect of 6 month supplemental milk protein intake on lean tissue mass in healthy adults aged 50 to 70 years
Norton, C,Toomey, C,McCormack, W,Francis, P,Jakeman, P
Proceedings Of The Nutrition Society DOI: 10.1017/S0029665115001998

2015

Dual energy x-ray absorptiometry based evaluation of elite Gaelic athletic association players
Davies, R,Hughes, K,Toomey, C,McCormack, W,Sinnott-O'Connor, C,Cremona, COA,Francis, P,Leahy, S,Jakeman, P
European Journal Of Clinical Nutrition

2015

A Review of Body Composition Measurement in the Assessment of Health
Toomey, CM,Cremona, A,Hughes, K,Norton, C,Jakeman, P
Topics In Clinical Nutrition DOI: 10.1097/TIN.0000000000000017

2013
2011

A comparison of the insulinotropic and enterogastric response to ingestion of an equivalent quantity of maltodextran and whey protein
Power, O,Conway, C,McCormack, W,Oharte, F,Fitzgerald, D,Jakeman, P
Proceedings Of The Nutrition Society DOI: 10.1017/S0029665111004423

2010

Can pre-feeding of a whey protein affect the glucoregulatory response to an oral glucose tolerance test?
Shaw, P,McCormac, W,McCarthy, B,Jakeman, P
Proceedings Of The Nutrition Society DOI: 10.1017/S0029665110002521

2010

A dual X-ray absorptiometry-based analysis of body fat distribution in healthy young adult women
Raftery, P,Boland, G,Leahy, S,Jakeman, P
Proceedings Of The Nutrition Society DOI: 10.1017/S0029665110002235

2007

Angiogenin levels in cerebrospinal fluid
Phukan, J; McCormack, W; Anderson, P; Jakeman, P; Hardiman, O
Journal Of Neurology

2007

Post-exercise feeding of carbohydrate-protein beverages on subsequent endurance performance
Rossiter, A., Jakeman, P., O'Sullivan, A., and Dunne, C.
Med Sci Sports Exerc

2006

Alterations in IGF bioavailability during progression of amyotrophic lateral sclerosis
Hosback, S; Jakeman, P; Nolan, C; Doyle, M; O'Toole, O; Gorman, G; Lynch, C; Hardiman, O
Journal Of Neurology

2005

Insulin-like growth factors are up-regulated in interferon-treated relapsing-remitting multiple sclerosis
Hosback, S; Jakeman, P; Gorman, G; O'Toole, O; Nolan, C; Lynch, C; Doyle, M; Hardiman, O
Journal Of Neurology

2003

Acute effects of anaerobic and aerobic exercise on bone turnover in healthy postmenopausal women
Loughnane, M; Murphy, N; Donnelly, R; Barrett, V; Barry, D; Jakeman, PM; Carroll, P
Osteoporosis International

2002

Biochemical markers of bone resorption
Jakeman, PM
American Journal Of Pharmaceutical Education

1999

Biochemical Limitations to Sports Performance
Jakeman, PM
American Journal Of Physiology-Heart And Circulatory Ph

1999
1999

Brain serotoninergic function and fatigue: modification by endurance training
Jakeman, PM
American Journal Of Pharmaceutical Education

1998

Advances in Endurance Training
Jakeman, PM
American Journal Of Physiology-Heart And Circulatory Ph

1997
1997

Effect of pre-exercise dietary manipulation on the IGF-1 and IGFBP-1 response to prolonged exercise in elite cyclists.
Welsh, LJ; Whitley, HA; Holly, JMP; Keegan, MA; Jakeman, PM
JOURNAL OF PHYSIOLOGY-LONDON

1996

Central vs. Peripheral Fatigue during Exercise
Jakeman, PM
American Journal Of Pharmaceutical Education

1996

Physiology of Fatigue During Prolonged Exercise
Jakeman, PM
American Journal Of Pharmaceutical Education

1995

Exercise-induced adaptation in central 5-HT sensitivity
Jakeman, PM
American Journal Of Pharmaceutical Education

1994

Central Aspects of Fatigue During Exercise: Human Studies
Jakeman, PM
American Journal Of Pharmaceutical Education

1994

IGF-BP1 response to prolonged exercise with and without oral glucose feeding
Jakeman, PM
American Journal Of Pharmaceutical Education

1990

THE MEASUREMENT OF SKELETAL-MUSCLE BUFFER VALUE IN MAN
MANNION, AF,JAKEMAN, PM,WILLAN, PLT
Journal Of Physiology-London

Peer Reviewed Journal

2017

Measurement of muscle health in aging
Francis, P,Lyons, M,Piasecki, M,Mc Phee, J,Hind, K,Jakeman, P
Biogerontology DOI: 10.1007/s10522-017-9697-5

2017

Seasonal changes in body composition of inter-county Gaelic Athletic Association hurlers
Davies, RW,Toomey, C,McCormack, W,O'Neill, C,Hughes, K,Jakeman, P
Journal Of Sports Sciences DOI: 10.1080/02640414.2016.1272709

2017

Measurement of maximal isometric torque and muscle quality of the knee extensors and flexors in healthy 50-to 70-year-old women
Francis, P,Toomey, C,Mc Cormack, W,Lyons, M,Jakeman, P
Clinical Physiology And Functional Imaging DOI: 10.1111/cpf.12332

2017
2017

Muscle strength can better differentiate between gradations of functional performance than muscle quality in healthy 50â€'70 y women
Francis, P. and McCormack, W. and Toomey, C. and Lyons, M. and Jakeman, P.
Brazilian Journal of Physical Therapy DOI: 10.1016/j.bjpt.2017.06.013

2016

Measurement of maximal isometric torque and muscle quality of the knee extensors and flexors in healthy 50 – 70y women
Francis, P., Toomey, C., McCormack, W., Lyons, M. and Jakeman, P.
Clinical Physiology And Functional Imaging DOI: 10.1111/cpf.12332.

2016

Evaluation of the antioxidant capacity of a milk protein matrix in vitro and in vivo in women aged 50-70 years
Power-Grant, O,McCormack, WG,De Cap, MR,Amigo-Benavent, M,Fitzgerald, RJ,Jakeman, P
International Journal Of Food Sciences And Nutrition DOI: 10.3109/09637486.2016.1153607

2016

Evaluation of the antioxidant capacity of a milk protein matrix in vitro and in vivo in women aged 50-70 years
Power-Grant, O. and McCormack, W.G. and Ramia De Cap, M. and Amigo-Benavent, M. and Fitzgerald, R.J. and Jakeman, P.
International Journal of Food Sciences and Nutrition DOI: 10.3109/09637486.2016.1153607

2016

Protein supplementation at breakfast and lunch for 24 weeks beyond habitual intakes increases whole-body lean tissue mass in healthy older adults
Norton, C. and Toomey, C. and McCormack, W.G. and Francis, P. and Saunders, J. and Kerin, E. and Jakeman, P.
Journal of Nutrition DOI: 10.3945/jn.115.219022

2016

A Comparison of Stride Length and Lower Extremity Kinematics during Barefoot and Shod Running in Well Trained Distance Runners
Francis, P,Ledingham, J,Clarke, S,Collins, DJ,Jakeman, P
Journal of Sports Science and Medicine

2016

Optimization of an in vitro bioassay to monitor growth and formation of myotubes in real time
Murphy, SM,Kiely, M,Jakeman, PM,Kiely, PA,Carson, BP
Bioscience reports DOI: 10.1042/BSR20160036

2016

Body composition analysis of inter-county Gaelic athletic association players measured by dual energy X-ray absorptiometry
Davies, R.W. and Toomey, C. and McCormack, W. and Hughes, K. and Cremona, A. and Jakeman, P.
Journal of Sports Sciences DOI: 10.1080/02640414.2015.1085076

2015

Body composition analysis of inter-county Gaelic athletic association players measured by dual energy X-ray absorptiometry
Davies, R. W. and Toomey, C. and McCormack, W. and Hughes, K. and Cremona, A. and Jakeman, P.
J Sports Sci DOI: 10.1080/02640414.2015.1085076

2015

A review of body composition measurement in the assessment of health
Toomey, C.M. and Cremona, A. and Hughes, K. and Norton, C. and Jakeman, P.
Topics in Clinical Nutrition DOI: 10.1097/TIN.0000000000000017

2015

Body composition analysis of inter-county Gaelic athletic association players measured by dual energy X-ray absorptiometry
Davies, R. W.,Toomey, C.,McCormack, W.,Hughes, K.,Cremona, A.,Jakeman, P.
J Sports Scij Sports Sci DOI: 10.1080/02640414.2015.1085076

2015

In vitro bioactive properties of intact and enzymatically hydrolysed whey protein: targeting the enteroinsular axis
Power-Grant, O,Bruen, C,Brennan, L,Giblin, L,Jakeman, P,FitzGerald, RJ
Food & Function DOI: 10.1039/c4fo00983e

2015

A Review of Body Composition Measurement in the Assessment of Health
Toomey, Clodagh M. and Cremona, Alexandra and Hughes, Katie and Norton, Catherine and Jakeman, Phil
Topics in Clinical Nutrition DOI: 10.1097/tin.0000000000000017

2015

In vitro bioactive properties of intact and enzymatically hydrolysed whey protein: targeting the enteroinsular axis
Power-Grant, O. and Bruen, C. and Brennan, L. and Giblin, L. and Jakeman, P. and FitzGerald, R. J.
Food Funct DOI: 10.1039/c4fo00983e

2014
2013

The effect of behavioural risk factors on osteoporosis in Irish women
Cummins, NM,Jakeman, PM,Sestak, I,Murphy, N,Carroll, P
Irish journal of medical science DOI: 10.1007/s11845-012-0840-7

2012

Regional grey and white matter volumetric changes in myalgic encephalomyelitis (chronic fatigue syndrome): a voxel-based morphometry 3 T MRI study
Puri, BK,Jakeman, PM,Agour, M,Gunatilake, KDR,Fernando, KAC,Gurusinghe, AI,Treasaden, IH,Waldman, AD,Gishen, P
British Journal Of Radiology DOI: 10.1259/bjr/93889091

2012

ULTRASOUND MEASUREMENT OF SUBCUTANEOUS ADIPOSE TISSUE THICKNESS ACCURATELY PREDICTS TOTAL AND SEGMENTAL BODY FAT OF YOUNG ADULTS
Leahy, Siobhan and Toomey, Clodagh and McCreesh, Karen and O'Neill, Cian and Jakeman, Philip
Ultrasound in Medicine and Biology DOI: 10.1016/j.ultrasmedbio.2011.10.011

2012
2011

Soccer-specific endurance and running economy in soccer players with cerebral palsy
Kloyiam, S. and Breen, S. and Jakeman, P. and Conway, J. and Hutzler, Y.
Adapt Phys Activ Q

2011

Soccer-Specific Endurance and Running Economy in Soccer Players With Cerebral Palsy
Kloyiam, S; Breen, S; Jakeman, P; Conway, J; Hutzler, Y
Adapted Physical Activity Quarterly

2010

Angiogenin Levels and ANG Genotypes: Dysregulation in Amyotrophic Lateral Sclerosis
McLaughlin, RL; Phukan, J; McCormack, W; Lynch, DS; Greenway, M; Cronin, S; Saunders, J; Slowik, A; Tomik, B; Andersen, PM; Bradley, DG; Jakeman, P; Hardiman, O
Plos One DOI: 10.1371/journal.pone.0015402

2010

Raman spectroscopy of fingernails: A novel tool for evaluation of bone quality?
Cummins, N. M. and Day, J. C. C. and Wren, A. and Carroll, P. and Murphy, N. and Jakeman, P. M. and Towler, M. R.
Spectroscopy-an International Journal DOI: 10.3233/SPE-2010-0471

2010

Citrulline malate enhances athletic performance and relieves muscle soreness
Perez-Guisado, J; Jakeman, PM
Journal Of Strength And Conditioning Research DOI: 10.1519/JSC.0b013e3181cb28e0

2010

Angiogenin levels and ANG genotypes: dysregulation in amyotrophic lateral sclerosis
McLaughlin, R. L. and Phukan, J. and McCormack, W. and Lynch, D. S. and Greenway, M. and Cronin, S. and Saunders, J. and Slowik, A. and Tomik, B. and Andersen, P. M. and Bradley, D. G. and Jakeman, P. and Hardiman, O.
PLoS One DOI: 10.1371/journal.pone.0015402

2008

A comparison of carbon dioxide emsiions associated with motorised transport modes and cycling in Ireland
Walsh, C; Jakeman, P; O'Regan, B; Moles, R
Transportation Research Part D: Transport And Environment

2007

Circulating insulin-like growth factors and related binding proteins are selectively altered in amyotrophic lateral sclerosis and multiple sclerosis
Hosback, S. and Hardiman, O. and Nolan, C. M. and Doyle, M. A. and Gorman, G. and Lynch, C. and O'Toole, O. and Jakeman, P.
Growth Horm IGF Res DOI: 10.1016/j.ghir.2007.06.002

2007

Circulating insulin-like growth factors and related binding proteins are selectively altered in amyotrophic lateral sclerosis and multiple sclerosis
Hosback, S; Hardiman, O; Nolan, CM; Maria, ACDBBBA; Gorman, G; Lynch, C; O'Toole, O; Jakeman, P
Growth Hormone & Igf Research DOI: DOI 10.1016/j.ghir.2007.06.002

2007

Raman spectroscopy of the human nail: A potential tool for evaluating bone health?
Towler, M. R. and Wren, A. and Rushe, N. and Saunders, J. and Cummins, N. M. and Jakeman, P. M.
Journal of Materials Science-Materials in Medicine DOI: 10.1007/s10856-006-0018-9

2007

Circulating insulin-like growth factors and related binding proteins are selectively altered in amyotrophic lateral sclerosis and multiple sclerosis.
Hosback, S; Hardiman, O; Nolan, CM; Doyle, MAC; Gorman, G; Lynch, C; O'Toole, O; Jakeman, P
Growth Hormone And Igf Research

2007

Angiogenin levels in cerebrospinal fluid
Phukan, J. and McCormack, W. and Anderson, P. and Jakeman, P. and Hardiman, O.
Journal of Neurology

2006

Alterations in IGF bioavailability during progression of amyotrophic lateral sclerosis
Hosback, S. and Jakeman, P. and Nolan, C. and Doyle, M. and O'Toole, O. and Gorman, G. and Lynch, C. and Hardiman, O.
Journal of Neurology

2006

Local changes in the insulin-like growth factor system in human skeletal muscle assessed by microdialysis and arterio-venous differences technique
Berg, U; Gustafsson, T; Sundberg, CJ; Carlsson-Skwirut, C; Hall, K; Jakeman, P; Bang, P
Growth Hormone & Igf Research DOI: 10.1016/j.ghir.2006.05.004

2006

Local changes in the insulin-like growth factor system in human skeletal muscle assessed by microdialysis and arterio-venous differences technique
Berg, U. and Gustafsson, T. and Sundberg, C. J. and Carlsson-Skwirut, C. and Hall, K. and Jakeman, P. and Bang, P.
Growth Hormone & Igf Research DOI: 10.1016/j.ghir.2006.05.004

2005

Insulin like growth factors levels in motor neuron disease
O'Toole, O and Gorman, G and Lynch, C and Hosback, S and Doyle, M and Long, J and Nolan, C and Jakeman, P and Hardiman, O
Journal of Neurology

2005

Influence Of Long-term Physical Activity And Short-term Exercise Training On Circulating Insulin-like Growth Factor I And Its Binding Proteins
Egan, Brendan,Jakeman, Philip M.
Medicine And Science In Sports And Exercisemedicine And Science In Sports And Exercise DOI: 10.1097/00005768-200505001-01241

2005

Insulin-like growth factors are up-regulated in interferon-treated relapsing-remitting multiple sclerosis.
Hosback, S; Jakeman, P; Gorman, G; O'Toole, O; Nolan, C; Lynch, C; Doyle, M; Hardiman, O
Journal Of Neurology

2005

Insulin like growth factors levels and impaired glucose tolerance in post polio patients
O'Toole, O,Gorman, G,Lynch, C,Hosback, S,Phukan, J,Doyle, M,Long, J,Nolan, C,Jakeman, P,Hardiman, O
Journal Of Neurologyjournal Of Neurology

2005

Insulin-like growth factor levels and impaired glucose tolerance in post-polio patients.
O'Toole, O; Gorman, G; Lynch, C; Hosback, S; Phukan, J; Doyle, M; Long, J; Nolan, C; Jakeman, P; Hardiman, O
Journal Of Neurology

2005

Insulin-like growth factors are up-regulated in interferon-treated relapsing-remitting multiple sclerosis
Hosback, S and Jakeman, P and Gorman, G and O'Toole, O and Nolan, C and Lynch, C and Doyle, M and Hardiman, O
Journal of Neurology

2005

Insulin like growth factors levels and impaired glucose tolerance in post polio patients
O'Toole, O and Gorman, G and Lynch, C and Hosback, S and Phukan, J and Doyle, M and Long, J and Nolan, C and Jakeman, P and Hardiman, O
Journal of Neurology

2005

Insulin-like growth factor levels in motor neuron disease.
O'Toole, O; Gorman, G; Lynch, C; Hosback, S; Doyle, M; Long, J; Nolan, C; Jakeman, P; Hardiman, O
Journal Of Neurology

2003

Biological and analytical variability of biochemical markers specific for bone formation and resorption in healthy men.
Carroll, P; Hunter, A; Barry, D; Barrett, N; Jakeman, PM
Journal Of Physiology

2003

Acute effects of anaerobic exercise on bone turnover in healthy post-menopausal women.
Carroll, P; Murphy, N; Donnelly, R; Barry, D; Barrett E; Loughnane, M; Jakeman, PM
Nat. Inst. Of Health Sciences Research Bulletin

2003

Commentary
Jakeman P
British Journal Of Sports Medicinebritish Journal Of Sports Medicine

2003

Insulin-like growth factors in motor neurone disease and other neurological conditions.
O'Toole, O.,Gorman, G.,Lynch, C.,Hosback, S.,Doyle, M.,Long, J.,Nolan, C.,Jakeman, P.
European Journal Of Neurologyeuropean Journal Of Neurology

2002

The components of variance and the critical difference in specific markers of bone turnover in healthy adult males and postmenopausal women.
Carroll, P; Hunter, A; Barry, D; Barrett, E; Loughnane, M; Donnelly, R; Murphy, N; Jakeman, PM
Nat. Inst. Of Health Sciences Research Bulletin

2002

Biological day-to-day variability and critical differences in the serial measurement of two markers of bone turnover in the sera of healthy young males. National
Carroll, P; Hunter, A; Barry, D; Barrett, E; Loughnane, M; Donnelly, R; Murphy, N; Jakeman, PM
Nat. Inst. Of Health Sciences Research Bulletin

2002

Circulating insulin-like growth factor system in chronic neurological disease states.
Hosback, S; Doyle, M; Gorman, G; Hardiman, O; Nolan, K; Jakeman, P
Growth Hormone And Igf Research

2001

Exercise-induced modification of insulin-like growth factor binding proteins in Man.
Keogh, R; Jakeman, PM
Irish Journal Of Medical Science

2000

Adaptation of the cardiovascular system in the elderly: dynamic vs. static exercise training.
Murphy-Griffin, M; Jakeman, PM; Horgan, JH
Irish Journal Of Medical Science

1997

Is human capillary skeletal muscle capillary supply modelled according to fibre size or fibre type ?
Ahmed, SK; Egginton, S; Jakeman, PM; Mannion, AF; Ross, HF
Experimental Physiology

1997

Is human skeletal muscle capillary supply modelled according to fibre size or fibre type?
Ahmed S.K., Egginton S., Jakeman P.M., Mannion A.F., Ross H.F.
Experimental Physiology

1996

The effect of oral creatine supplementation on the 1000-m performance of competitive rowers
Rossiter H.B., Cannell E.R., Jakeman P.M.
Journal Of Sports Sciences

1996

The effect of oral creatine supplementation on 1km simulated rowing.
Rossiter, HB; Jakeman, PM; Cannell, ER
Journal Of Sports Science

1995

Cellular immune activity in response to increased training of elite oarsmen prior to Olympic competition
Jakeman, P. M.,Weller, A.,Warrington, G.
Journal Of Sports Sciencesjournal Of Sports Sciences DOI: 10.1080/02640419508732229

1995
1995

AN EVALUATION OF THE VARIABILITY IN PROLACTIN SECRETION IN RESPONSE TO THE SEROTONINERGIC AGONIST D-FENFLURAMINE IN MAN
GREENHOW, S,JAKEMAN, PM,KENDALL, MJ,DOWLING, BA,FRANKLIN, M
Journal Of Physiology-Londonjournal Of Physiology-London

1995
1995
1995

Skeletal muscle buffer value, fibre type distribution and high intensity exercise performance in man
Mannion, A. F.,Jakeman, P. M.,Willan, P. L.
Exp Physiolexp Physiol

1995

GASPAR - TASK-SPECIFIC IMAGE-ANALYSIS SOFTWARE FOR USE WITH HUMAN MUSCLE HISTOLOGY
RIVAS, M,SKRONE, J,CLARIDGE, E,JAKEMAN, P,EGGINTON, S
Journal Of Physiology-Londonjournal Of Physiology-London

1995

Analysis of IGFBP-3 and protease activity during prolonged submaximal exercise to fatigue in man
Cwyfan-Hughes, S. C.,Jakeman, P.,Hopkins, N.,Holly, J. M. P.
Journal Of Endocrinologyjournal Of Endocrinology

1994

Effects of isokinetic training of the knee extensors on high-intensity exercise performance and skeletal muscle buffering
Mannion, A. F.,Jakeman, P. M.,Willan, P. L.
Eur J Appl Physiol Occup Physioleur J Appl Physiol Occup Physiol

1994

Functional outcome after treatment of malignant bone tumours around the knee.
Roberts, P; Ratcliffe, PJ; Jakeman, PM; Michael, S; Grimer, RJ
J. Bone And Joint Surgery

1994

The effect of alcohol on physiological tremor
Lakie, M.,Frymann, K.,Villagra, F.,Jakeman, P.
Exp Physiolexp Physiol

1994

Is muscle capillary supply modelled according to fibre size or fibre type?
Jakeman, PM; Hornsey, P; Eggington, SE; Mannion, AF
Journal Of Sports Science

1994

Evidence for downregulation of hypothalamic 5-hydroxytryptamine receptor function in endurance-trained athletes
Jakeman, P. M.,Hawthorne, J. E.,Maxwell, S. R.,Kendall, M. J.,Holder, G.
Exp Physiolexp Physiol

1994

A review of research in Sports Physiology.
Jakeman, PM; Winter, EM; Doust, J
Journal Of Sports Science

1994

Evidence of downregulation of hypothalamic 5-hydroxytryptamine receptor function in endurance trained athletes
Jakeman, PM; Hawthorne, JE; Maxwell, SRJ; Kendall, MJ; Holder, G
Experimental Physiology

1994

Effect of alcohol on physiological tremor.
Lakie, M; Fryman, K; Villagra, F; Jakeman, PM
Experimental Physiology

1993

EFFECT OF VITAMIN SUPPLEMENTATION ON MUSCLE FUNCTION AFTER ECCENTRIC EXERCISE
JAKEMAN, P,MAXWELL, S,ROWBOTTOM, D,GRIMES, E
Journal Of Physiology-Londonjournal Of Physiology-London

1993

Eccentric exercise causes an acute increase in serum antioxidant capacity
Maxwell, S. R. J.,Jakeman, P.,Leguen, C.,Thomason, H.,Thorpe, G. H. G.
Clinical Science (London)Clinical Science (London)

1993

CELLULAR IMMUNE ACTIVITY IN RESPONSE TO INCREASED TRAINING OF THE ELITE ATHLETE
JAKEMAN, P,HOPKINS, D,WARRINGTON, G
Journal Of Physiology-Londonjournal Of Physiology-London

1993

Determination of human muscle buffer value by the homogenate technique: methods of measurement.
Mannion, AF; Jakeman, PM; Willan, PLT
Journal Of Applied Physiology

1993

Effect of antioxidant vitamin supplementation on muscle function after eccentric exercise
Jakeman, P.,Maxwell, S.
Eur J Appl Physiol Occup Physioleur J Appl Physiol Occup Physiol

1993

The impact of a short course of three lipid lowering drugs on fat oxidation during exercise in healthy volunteers
Head, A.,Jakeman, P. M.,Kendall, M. J.,Cramb, R.,Maxwell, S.
Postgrad Med Jpostgrad Med J

1993

Changes in plasma antioxidant status during eccentric exercise and the effect of vitamin supplementation.
Maxwell SRJ; Jakeman, PM; Thomason, H; Leguen, C; Thorpe, GHC
Free Radical Research Communication

1993

The impact of a short course of lipid lowering drugs on exercise metabolism.
Head, A; Jakeman, PM; Kendall, MJ; Cramb, B; Maxwell, SRJ
Postgraduate Medical Journal

1993

Cellular immune activity in response to increased training of the elite athlete
Jakeman, P. and Hopkins, D. and Warrington, G.
Journal of Physiology

1993
1993

Changes in plasma antioxidant status during eccentric exercise and the effect of vitamin supplementation
Maxwell, S. R.,Jakeman, P.,Thomason, H.,Leguen, C.,Thorpe, G. H.
Free Radic Res Communfree Radic Res Commun

1992

Carnosine and anserine concentrations in the quadriceps muscle of healthy humans.
Mannion, AF; Jakeman, PM; Dunnett, M; Harris, RC; Willan, PLT
European Journal Of Applied Physiology And Occupatioal

1992

Effects of isokinetic training of the knee extensors on isometric strength and peak power output during cycling
Mannion, A. F.,Jakeman, P. M.,Willan, P. L.
Eur J Appl Physiol Occup Physioleur J Appl Physiol Occup Physiol

1992

Effect of isokinetic training of the knee extensors on isometric strength and peak power output during cycling.
Mannion, AF; Jakeman, PM; Willan, PLT
European Journal Of Applied Physiology And Occupatioal

1992

Carnosine and anserine concentrations in the quadriceps femoris muscle of healthy humans
Mannion, A. F.,Jakeman, P. M.,Dunnett, M.,Harris, R. C.,Willan, P. L. T.
European Journal Of Applied Physiology And Occupational Physiologyeuropean Journal Of Applied Physiology And Occupational Physiology DOI: 10.1007/BF00376439

1992

EFFECTS OF ISOKINETIC TRAINING OF THE KNEE EXTENSORS ON ISOMETRIC STRENGTH AND PEAK POWER OUTPUT DURING CYCLING
MANNION, AF,JAKEMAN, PM,WILLAN, PLT
European Journal Of Applied Physiology And Occupational Physiologyeuropean Journal Of Applied Physiology And Occupational Physiology DOI: 10.1007/BF00868143

1990

THE MEASUREMENT OF SKELETAL-MUSCLE BUFFER VALUE IN MAN
MANNION, AF,JAKEMAN, PM,WILLAN, PLT
Journal Of Physiology-Londonjournal Of Physiology-London

1990

THE CONTRIBUTION OF CARNOSINE TO SKELETAL-MUSCLE BUFFERING IN MAN
MANNION, AF,JAKEMAN, PM,DUNNETT, M,HARRIS, R,WILLAN, PLT
Journal Of Physiology-Londonjournal Of Physiology-London

1988

Precompetitive anxiety and motor performance: a psychophysiological examination
Smith, N. C.,Burwitz, L.,Jakeman, P.
J Sports Scij Sports Sci DOI: 10.1080/02640418808729802

1984

Maximum oxygen uptake utilising different treadmill protocols.
Davies, B,Daggett, A,Jakeman, P,Mulhall, J
British Journal Of Sports Medicine

1984

Physiological changes and sleep responses during and following a world record continuous walking record
Davies, B.,Shapiro, C. M.,Daggett, A.,Gatt, J. A.,Jakeman, P.
Br J Sports Medbr J Sports Med