Biography

Dr. Austin G. Stack, MD, MSc, FRCPI, FASN is a Consultant Nephrologist in Ireland and Professor and Chair of Medicine at the University of Limerick. Prior to his current appointment; he was Associate Professor in Medicine at the University of Texas, Houston, U.S.A. and Director of the Clinical Research Outcomes Program (2001-2004) in the Division of Renal Diseases and Hypertension.

Dr. Stack completed his residency training in Ireland and nephrology fellowship at the University of Michigan. He studied Clinical Research Design and Statistical Analysis (MSc) at the University of Michigan and was appointed to the research teams at the Kidney Epidemiology and Cost Centre (KECC), and US Renal Data System (USRDS). In 2001, he joined the Renal Division at the University of Texas as Assistant Professor of Medicine and led a successful epidemiological research and mentorship program until his move to Ireland in 2005. He was awarded his MD in Medicine (Epidemiology) in 2005.

Dr Stack has significant experience in the conduct of health outcomes and population health research in chronic kidney disease (CKD). His scientific interests include cardiovascular disease epidemiology, risk assessment, mineral metabolism, comparative effectiveness research and the identification of modifiable clinical practices in CKD. He is currently using national and regional datasets in Ireland and the US to explore several important questions. In Ireland, he is advancing the application of IT communications systems to bolster clinical and epidemiological research. As Clinical Director of the National Renal Information Project (2008), he directs the implementation of a single state-wide renal information system (eMED) for patients with kidney disease and leads a national effort to establish a CKD Surveillance System. Dr Stack is a new member of the UM-KECC team and contributes to the current CKD Surveillance project as co-investigator.

Research Interests


My research is focused on better understanding the epidemiology, risk, clinical outcomes and treatment strategies for Chronic Kidney Disease (CKD) and Acute Kidney Injury (AKI).
We are particularly interested in understanding the relationship between AKI, CKD and major clinical outcomes as well as preventive strategies using large national and international data.

Using data from the National Health and Examination Surveys (NHANES) and the US Renal Data System (USRDS), we have described the burden and clinical outcomes of several cardiovascular diseases in this vulnerable population. Our group has also advanced our understanding of treatment outcomes in dialysis and optimal dialysis strategies. Specific themes include, cardiovascular diseases and their treatment, mineral bone disease, dialysis strategies, medication prescribing, adherence to clinical guidelines, and gout and hyperuricaemia.

Our team at the Graduate Entry Medical School (GEMS) have been awarded two (3-year) HRB grants to study the epidemiology of Chronic Kidney Disease (CKD) and Acute Kidney Injury (AKI) in the Irish Health System. These studies will also provide a framework for the development of national surveillance systems that can be successfully used to track the burden, clinical outcomes and cost of kidney disease care in the health system. In support of this initiative, we also work with the HSE in the deployment of national IT system in nephrology which will be used to bolster clinical and epidemiological research in Ireland. Emerging areas of interest include Big Data in health and Connected Health in order to improve health system performance and overall patient outcomes.

Books

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Book Chapters

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Edited Books

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Peer Reviewed Journals

Survival advantage of Hispanic patients initiating dialysis in the United States is modified by race.

Prof. Austin Stack
2005
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Association of patient autonomy with increased transplantation and survival among new dialysis patients in the United States.

Prof. Austin Stack
2005
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Pulmonary congestion in hemodialysis: an old chestnut worth screening for?

Prof. Austin Stack
2013
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Survival differences between peritoneal dialysis and hemodialysis among "large" ESRD patients in the United States.

Prof. Austin Stack
2004
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Surveillance of Chronic Kidney Disease around the World: Tracking and Reigning in a Global Problem.

Prof. Austin Stack
2010
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Ethnic disparities in cardiovascular risk factors and coronary disease prevalence among individuals with chronic kidney disease: findings from the Third National Health and Nutrition Examination Survey.

Prof. Austin Stack
2006
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Renal replacement therapy in the elderly: medical, ethical, and psychosocial considerations.

Prof. Austin Stack
2000
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Cigarette use and cardiovascular risk in chronic kidney disease: an unappreciated modifiable lifestyle risk factor.

Prof. Austin Stack
2010
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Ethnic Disparities in Cardiovascular Risk Factors and Coronary Disease Prevalence among Persons with Chronic Kidney Disease: Findings from the Third National Health and Nutrition Examination Survey (NHANES III)

Prof. Austin Stack
2006
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Coronary artery disease and peripheral vascular disease among patients with chronic kidney disease: An epidemiological perspective.

Prof. Austin Stack
2005
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Coronary artery disease and peripheral vascular disease in chronic kidney disease: an epidemiological perspective.

Prof. Austin Stack
2005
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Independent and conjoint associations of gout and hyperuricaemia with total and cardiovascular mortality.

Prof. Austin Stack
2013
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Determinants and prognostic importance of cardiomegaly among new ESRD patients in the United States.

Prof. Austin Stack
2004
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Survival trends of new US dialysis patients with Heart Failure: 1995-2005.

Prof. Austin Stack
2011
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Independent and conjoint associations of gout and hyperuricaemia with total and cardiovascular mortality

Prof. Austin Stack
2013
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A cross-sectional study of the prevalence and clinical correlates of congestive heart failure among incident US dialysis patients.

Prof. Austin Stack
2001
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Transferrin saturation ratio and risk of total and cardiovascular mortality in the general population.

Prof. Austin Stack
2014
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Exercise and limitations in physical activity levels among new dialysis patients in the United States: an epidemiologic study.

Prof. Austin Stack
2008
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The Impact of Chronic Obstructive Pulmonary Disease and Smoking on Mortality and Kidney Transplantation in End-Stage Kidney Disease

Prof. Austin Stack
2012
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Prevalence and clinical correlates of coronary artery disease among new dialysis patients in the United States: a cross-sectional study.

Prof. Austin Stack
2001
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Impact of years of dialysis therapy on mortality risk and the characteristics of longer term dialysis survivors.

Prof. Austin Stack
2002
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Plasma fibrinogen associates independently with total and cardiovascular mortality among subjects with normal and reduced kidney function in the general population.

Prof. Austin Stack
2014
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Prevalence and variation of Chronic Kidney Disease in the Irish health system: initial findings from the National Kidney Disease Surveillance Programme

Prof. Austin Stack
2014
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The impact of chronic obstructive pulmonary disease on mortality and kidney transplantation in end-stage kidney disease

Prof. Austin Stack
2012
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Association of elevated serum PO(4), Ca x PO(4) product, and parathyroid hormone with cardiac mortality risk in chronic hemodialysis patients.

Prof. Austin Stack
2001
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Clinical correlates and mortality impact of left ventricular hypertrophy among new ESRD patients in the United States.

Prof. Austin Stack
2002
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The impact of chronic obstructive pulmonary disease and smoking on mortality and kidney transplantation in end-stage kidney disease.

Prof. Austin Stack
2012
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Transferrin saturation ratio: a method to estimate risk of cardiovascular mortality in the general population?

Prof. Austin Stack
2014
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Exercise and Limitations in Physical Activity Levels among New Dialysis Patients in the United States

Prof. Austin Stack
2008
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Determinants of modality selection among incident US dialysis patients: results from a national study.

Prof. Austin Stack
2002
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Impact of timing of nephrology referral and pre-ESRD care on mortality risk among new ESRD patients in the United States.

Prof. Austin Stack
2003
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Declining mortality rates despite increases in clinical coronary artery disease among US dialysis patients: a national registry study.

Prof. Austin Stack
2013
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Remote ischemic conditioning and renal function after contrast-enhanced CT scan: A randomized trial

Prof. Austin Stack
2015
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Cigarette Use and Cardiovascular Risk in Chronic Kidney Disease: An Unappreciated Modifiable Lifestyle Risk Factor.

Prof. Austin Stack
2010
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Mortality differences by dialysis modality among incident ESRD patients with and without coronary artery disease.

Prof. Austin Stack
2003
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Association of physical activity with mortality in the US dialysis population.

Prof. Austin Stack
2005
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Survival trends of US dialysis patients with heart failure: 1995 to 2005.

Prof. Austin Stack
2011
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Impact of dialysis modality on survival of new ESRD patients with congestive heart failure in the United States.

Prof. Austin Stack
2003
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A diabetic male with acute renal failure: a cautionary tale

Prof. Austin Stack
2008
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Other Journals

This author has not written any publications of this type yet.

Conference Publications

12th Asian-Pacific International Congress of Nephrology

Prof. Austin Stack
2010
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American Society of Nephrology

Prof. Austin Stack
2010
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American Society of Nephrology

Prof. Austin Stack
2011
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12th Asian-Pacific International Congress of Nephrology

Prof. Austin Stack
2010
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World Congress of Nephrology

Prof. Austin Stack
2011
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American Society of Nephrology

Prof. Austin Stack
2011
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Irish Society of Nephrology

Prof. Austin Stack
2010
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Irish Society of Nephrology

Prof. Austin Stack
2011
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American Society of Nephrology

Prof. Austin Stack
2011
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Irish Society of Nephrology

Prof. Austin Stack
2010
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Irish Society of Nephrology

Prof. Austin Stack
2011
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Irish Society of Nephrology

Prof. Austin Stack
2012
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The Impact of Advancing Age on Coronary Disease Prevalence and Associated Mortality in End Stage Kidney Disease

Prof. Austin Stack
2012
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European Dialysis and Transplantation Congress

Prof. Austin Stack
2010
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Irish Society of Nephrology

Prof. Austin Stack
2011
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Irish Society of Nephrology

Prof. Austin Stack
2012
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PROGRESSION OF CHRONIC KIDNEY DISEASE IN THE IRISH POPULATION: INITIAL FINDINGS FROM A NATIONAL SURVEILLANCE PROGRAMME

Prof. Austin Stack
2013
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American Society of Nephrology

Prof. Austin Stack
2010
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Irish Society of Nephrology

Prof. Austin Stack
2011
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Irish Society of Nephrology

Prof. Austin Stack
2012
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Substantial Improvement in survival on Peritoneal dialysis versus Haemodialysis in the United States: A Longitudinal Trend Analysis, 1995-2004

Prof. Austin Stack
2010
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American Society of Nephrology

Prof. Austin Stack
2010
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Irish Society of Nephrology

Prof. Austin Stack
2011
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Irish Society of Nephrology

Prof. Austin Stack
2012
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British Renal Society-Renal Association

Prof. Austin Stack
2010
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American Society of Nephrology

Prof. Austin Stack
2010
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World Congress of Nephrology

Prof. Austin Stack
2011
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Conference Contributions

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Published Reports

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Editorials

Pulmonary Manifestations of Volume Expansion

Prof. Austin Stack
2015
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Pulmonary Congestion in Hemodialysis: An Old Chestnut Worth Screening For?

Prof. Austin Stack
2013
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Transferrin saturation ratio: a method to estimate risk of cardiovascular mortality in the general population?

Prof. Austin Stack
2014
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Book Reviews

This author has not written any publications of this type yet.

Other Publications

RELATIONSHIPS BETWEEN GLYCOSYLATED HAEMOGLOBIN AND DEATH AMONG DIABETIC PATIENTS UNDERGOING DIALYSIS: A NATIONAL COHORT STUDY

Prof. Austin Stack
2015
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ASSOCIATION OF SUBSTANCE ABUSE WITH MORTALITY AND KIDNEY TRANSPLANTATION AMONG NEW DIALYSIS PATIENTS

Prof. Austin Stack
2015
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RISK OF ISCHAEMIC STROKE FOR INCIDENT PATIENTS TREATED WITH PERITONEAL DIALYSIS VERSUS HAEMODIALYSIS

Prof. Austin Stack
2015
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LONG TERM CONSEQUENCES OF TRANSIENT ACUTE KIDNEY INJURY ON RISK OF DEATH AND KIDNEY FAILURE IN THE IRISH HEALTH SYSTEM

Prof. Austin Stack
2015
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Pulmonary Manifestations of Volume Expansion

Prof. Austin Stack
2015
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Transferrin saturation ratio: a method to estimate risk of cardiovascular mortality in the general population?

Prof. Austin Stack
2014
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Incidence of and Recovery from Acute Kidney Injury in the Irish Population

Prof. Austin Stack
2014
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THE RELATIONSHIP BETWEEN GLOMERULAR FILTRATION RATE AND MORTALITY AT DIALYSIS INITIATION IS INFLUENCED BY BLOOD UREA NITROGEN CONCENTRATIONS

Prof. Austin Stack
2013
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Pulmonary Congestion in Hemodialysis: An Old Chestnut Worth Screening For?

Prof. Austin Stack
2013
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IMPACT OF SMOKING ON RISK OF DEATH AND KIDNEY TRANSPLANTATION AMONG PATIENTS WITH CARDIOVASCULAR DISEASE AT DIALYSIS INITIATION: A NATIONAL COHORT STUDY

Prof. Austin Stack
2013
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PRACTICE PATTERNS IN BLOOD PRESSURE MANAGEMENT AND TARGETS AMONG NON-DIALYSIS CHRONIC KIDNEY DISEASE PATIENTS: RESULTS OF A MULTI-CENTRE AUDIT AND NATIONAL SURVEY

Prof. Austin Stack
2015
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CELLULAR COMPONENTS OF THE IMMUNE SYSTEM CONTRIBUTE INDEPENDENTLY TO OVERALL MORTALITY IN CHRONIC KIDNEY DISEASE BEYOND THE CLASSIC MARKERS OF SYSTEMIC INFLAMMATION

Prof. Austin Stack
2013
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