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Prof Austin Stack

MD,FRCPI,MSc

Biography

Dr. Austin G. Stack, MD, MSc, FRCPI, FASN is a Consultant Nephrologist in Ireland and Professor and Chair of Medicine at the University of Limerick. Prior to his current appointment; he was Associate Professor in Medicine at the University of Texas, Houston, U.S.A. and Director of the Clinical Research Outcomes Program (2001-2004) in the Division of Renal Diseases and Hypertension.


Dr. Stack completed his residency training in Ireland and nephrology fellowship at the University of Michigan. He studied Clinical Research Design and Statistical Analysis (MSc) at the University of Michigan and was appointed to the research teams at the Kidney Epidemiology and Cost Centre (KECC), and US Renal Data System (USRDS). In 2001, he joined the Renal Division at the University of Texas as Assistant Professor of Medicine and led a successful epidemiological research and mentorship program until his move to Ireland in 2005. He was awarded his MD in Medicine (Epidemiology) in 2005.


Dr Stack has significant experience in the conduct of health outcomes and population health research in chronic kidney disease (CKD). His scientific interests include cardiovascular disease epidemiology, risk assessment, mineral metabolism, comparative effectiveness research and the identification of modifiable clinical practices in CKD. He is currently using national and regional datasets in Ireland and the US to explore several important questions. In Ireland, he is advancing the application of IT communications systems to bolster clinical and epidemiological research. As Clinical Director of the National Renal Information Project (2008), he directs the implementation of a single state-wide renal information system (eMED) for patients with kidney disease and leads a national effort to establish a CKD Surveillance System. Dr Stack is a new member of the UM-KECC team and contributes to the current CKD Surveillance project as co-investigator.

Research Interests

                                              
My research is focused on better understanding the epidemiology, risk, clinical outcomes and treatment strategies for Chronic Kidney Disease (CKD) and Acute Kidney Injury (AKI). 
We are particularly interested in understanding the relationship between AKI, CKD and major clinical outcomes as well as preventive strategies using large national and international data.


Using data from the National Health and Examination Surveys (NHANES) and the US Renal Data System (USRDS), we have described the burden and clinical outcomes of several cardiovascular diseases in this vulnerable population. Our group has also advanced our understanding of treatment outcomes in dialysis and optimal dialysis strategies. Specific themes include, cardiovascular diseases and their treatment, mineral bone disease, dialysis strategies, medication prescribing, adherence to clinical guidelines, and gout and hyperuricaemia.


Our team at the Graduate Entry Medical School (GEMS) have been awarded two (3-year) HRB grants to study the epidemiology of Chronic Kidney Disease (CKD) and Acute Kidney Injury (AKI) in the Irish Health System. These studies will also provide a framework for the development of national surveillance systems that can be successfully used to track the burden, clinical outcomes and cost of kidney disease care in the health system.  In support of this initiative, we also work with the HSE in the deployment of national IT system in nephrology which will be used to bolster clinical and epidemiological research in Ireland. Emerging areas of interest include Big Data in health and Connected Health in order to improve health system performance and overall patient outcomes.  

                     

Publications

Conference Publication

2013

PROGRESSION OF CHRONIC KIDNEY DISEASE IN THE IRISH POPULATION: INITIAL FINDINGS FROM A NATIONAL SURVEILLANCE PROGRAMME
Stack, AG,Chernenko, T,Abdalla, AA,Saran, R,Nguyen, HT,Hedgeman, E,Hannigan, A,Casserly, LF

2012

The Impact of Advancing Age on Coronary Disease Prevalence and Associated Mortality in End Stage Kidney Disease
O'Hanlon, S,McNamara, R,Abdalla, A,Casserly, L,Cronin, C,Lyons, D,Stack, AG
Irish Journal Of Medical Science

2012

Irish Society of Nephrology
Donigiewicz, U; Abdalla, A; Weiland, A; Casserly, L; Cronin, C; Nguyen, H; Hannigan, A; Stack, A

2012

Irish Society of Nephrology
Abdalla, A; Weiland, A; Casserly, L; Cronin, C; Hannigan, A; Stack, AG

2012

Irish Society of Nephrology
Stack, AG; Abdalla, A; Cronin, C; Hannigan, A; Casserly, L

2012

Irish Society of Nephrology
Stack, AG; Casserly, L; Cronin, C; Nguyen, H; McElligott, A; Hannigan,A

2011

American Society of Nephrology
Stack, AG; Mutwali, A; Saran, R

2011

Irish Society of Nephrology
Mohammed, A; Hanley, A; Tan, S; Victor, P; Mutwali, A; Saran, R; Stack, AG

2011

Irish Society of Nephrology
Tan, S; Hanley, A; Mohammed, A; Stack, AG; Mutwali, A

2011

World Congress of Nephrology
Dyk, A; Phisitkul, K; Nguyen, H; Lappin, J; Stack, A; Murthy, B

2011

World Congress of Nephrology
Hanley, A; Mohammed, A; Mutwali, A; Murthy, BVR; Nguyen, H; Stack, AG

2011

Irish Society of Nephrology
Stack, AG; Hanley, A; Mohammed, A; Tan, S; Victor, P; Mutwali, A; Saran, R

2011

American Society of Nephrology
Stack, AG; Murthy, BVR; Mutwali, A; Nguyen, HT

2011

Irish Society of Nephrology
Hanley, A; Mohammed, A; Tan, S; Victor, P; O'Keeffe, P; Ishag, E; Abdeljalel, W; Mutwali, A; Stack, AG

2011

American Society of Nephrology
Stack, AG; Nguyen, HT; Murthy, BVR; Mutwali, A

2011

Irish Society of Nephrology
Stack, AG; Hanley, A; Mohammed, A; Murthy, BVR; Nguyen, H; Mutwali A

2010

Irish Society of Nephrology
Barrett, P; Hannan, K; Wall, CAM; Stack, AG

2010

American Society of Nephrology
Stack, AG; Nguyen, H; Hannan, K; Wall, CAM

2010

Irish Society of Nephrology
Stack, AG; Barrett, P; Yousif, I; Mutwali, A; Wall, CAM

2010

European Dialysis and Transplantation Congress
Stack, AG; Barrett, P; Yousif, I; McDaid, D; Nguyen, H; Hannan, K; Wall, CAM

2010

British Renal Society-Renal Association
McDaid, D; Yousif, I; Duncan, G; Mutwali, A; Stack, AG

2010

American Society of Nephrology
Stack, AG; Barrett, P; Yousif, I; McDaid, D; Mutwali, A; Wall, CAM

2010

12th Asian-Pacific International Congress of Nephrology
Stack AG, Barrett P, Yousif I, McDaid D, Mutwali A, Wall CAM.

2010

American Society of Nephrology
Barrett, P; Hannan, K; CAM, Wall; Stack, AG

2010

12th Asian-Pacific International Congress of Nephrology
Barrett, P; Patton, F; Yousif, I; Mutwali, A; Gilcreest, T; Clarke, J; Stack, AG

Other Publication

2015

ASSOCIATION OF SUBSTANCE ABUSE WITH MORTALITY AND KIDNEY TRANSPLANTATION AMONG NEW DIALYSIS PATIENTS
Elsayed, ME,Hickey, A,Sharif, M,Ferguson, JP,Stack, AG
Nephrology Dialysis Transplantation DOI: 10.1093/ndt/gfv183.26

2015

Pulmonary Manifestations of Volume Expansion
Elsayed, ME,Stack, AG
Seminars in dialysis DOI: 10.1111/sdi.12351

2015

RISK OF ISCHAEMIC STROKE FOR INCIDENT PATIENTS TREATED WITH PERITONEAL DIALYSIS VERSUS HAEMODIALYSIS
Stack, AG,Elsayed, ME,Sharif, MU,Moloney, MC,Ferguson, JP
Nephrology Dialysis Transplantation DOI: 10.1093/ndt/gfv155.1

2015

PRACTICE PATTERNS IN BLOOD PRESSURE MANAGEMENT AND TARGETS AMONG NON-DIALYSIS CHRONIC KIDNEY DISEASE PATIENTS: RESULTS OF A MULTI-CENTRE AUDIT AND NATIONAL SURVEY
Sharif, MU,Hanley, K,Ryan, L,Hannigan, A,Casserly, L,Ferguson, JP,Stack, AG
Nephrology Dialysis Transplantation

2015

RELATIONSHIPS BETWEEN GLYCOSYLATED HAEMOGLOBIN AND DEATH AMONG DIABETIC PATIENTS UNDERGOING DIALYSIS: A NATIONAL COHORT STUDY
Elsayed, ME,McCarthy, E,Hare, JO,Ferguson, JP,Stack, AG
Nephrology Dialysis Transplantation DOI: 10.1093/ndt/gfv183.34

2014

Incidence of and Recovery from Acute Kidney Injury in the Irish Population
Gillis, E,Ferguson, J,Elsayed, M,Mohamed, W,Stack, AG
Irish journal of medical science

2013

Pulmonary Congestion in Hemodialysis: An Old Chestnut Worth Screening For?
Stack, AG,Casserly, LF
Clinical Journal Of The American Society Of Nephrology DOI: 10.2215/CJN.06210613

Peer Reviewed Journal

2015

Remote ischemic conditioning and renal function after contrast-enhanced CT scan: A randomized trial
Healy, DA,Feeley, I,Keogh, CJ,Scanlon, TG,Hodnett, PA,Stack, AG,Moloney, MC,Whittaker, P,Walsh, SR
Clinical And Investigative Medicine

2014

Transferrin saturation ratio and risk of total and cardiovascular mortality in the general population.
Stack AG, Mutwali AI, Nguyen HT, Cronin CJ, Casserly LF, Ferguson J
QJM : monthly journal of the Association of Physicians DOI: 10.1093/qjmed/hcu045

2014

Prevalence and variation of Chronic Kidney Disease in the Irish health system: initial findings from the National Kidney Disease Surveillance Programme
Stack, AG,Casserly, LF,Cronin, CJ,Chernenko, T,Cullen, W,Hannigan, A,Saran, R,Johnson, H,Browne, G,Ferguson, JP
Bmc Nephrology DOI: 10.1186/1471-2369-15-185

2014

Plasma fibrinogen associates independently with total and cardiovascular mortality among subjects with normal and reduced kidney function in the general population.
Stack AG, Donigiewicz U, Abdalla AA, Weiland A, Casserly LF, Cronin CJ, Nguyen HT, Hannigan A
QJM : monthly journal of the Association of Physicians DOI: 10.1093/qjmed/hcu057

2013

Independent and conjoint associations of gout and hyperuricaemia with total and cardiovascular mortality.
Stack AG, Hanley A, Casserly LF, Cronin CJ, Abdalla AA, Kiernan TJ, Murthy BV, Hegarty A, Hannigan A, Nguyen HT
QJM : monthly journal of the Association of Physicians DOI: 10.1093/qjmed/hct083

2013

Pulmonary congestion in hemodialysis: an old chestnut worth screening for?
Stack AG, Casserly LF
Clinical journal of the American Society of Nephrology : CJASN DOI: 10.2215/CJN.06210613

2013

Independent and conjoint associations of gout and hyperuricaemia with total and cardiovascular mortality
Stack, AG,Hanley, A,Casserly, LF,Cronin, CJ,Abdalla, AA,Kiernan, TJ,Murthy, BVR,Hegarty, A,Hannigan, A,Nguyen, HT
Qjm-An International Journal Of Medicine DOI: 10.1093/qjmed/hct083

2013

Declining mortality rates despite increases in clinical coronary artery disease among US dialysis patients: a national registry study.
Cronin CJ, Nguyen HT, Casserly LF, Stack AG, Neylon AM, Abdalla AA, Hegarty A, Hannigan A
American journal of nephrology DOI: 10.1159/000353103

2012

The impact of chronic obstructive pulmonary disease and smoking on mortality and kidney transplantation in end-stage kidney disease.
Kent BD, Eltayeb EE, Woodman A, Mutwali A, Nguyen HT, Stack AG
American journal of nephrology DOI: 10.1159/000342207

2012

The Impact of Chronic Obstructive Pulmonary Disease and Smoking on Mortality and Kidney Transplantation in End-Stage Kidney Disease
Kent, BD,Eltayeb, EE,Woodman, A,Mutwali, A,Nguyen, HT,Stack, AG
American Journal Of Nephrology DOI: 10.1159/000342207

2012

The impact of chronic obstructive pulmonary disease on mortality and kidney transplantation in end-stage kidney disease
Kent, BD; Woodman, A; Elhadi, E; Mutwali, A; Nguyen, H; Stack AG
American Journal Of Nephrology

2011

Survival trends of new US dialysis patients with Heart Failure: 1995-2005.
Stack, AG; Mohammed, A; Hanley, A; Mutwali, A; Nguyen, HT
Clinical Journal Of The American Society Of Nephrology

2011

Survival trends of US dialysis patients with heart failure: 1995 to 2005.
Stack AG, Mohammed A, Hanley A, Mutwali A, Nguyen H
Clinical journal of the American Society of Nephrology : CJASN DOI: 10.2215/CJN.01130211

2010

Surveillance of Chronic Kidney Disease around the World: Tracking and Reigning in a Global Problem.
Saran, R; Hedgeman, E; Huseini, M; Stack, AG; Shahinian, V
Advances In Chronic Kidney Disease

2008

A diabetic male with acute renal failure: a cautionary tale
Gilbert, T; Duddy, M; O’ Shea, LA; Stack AG
Clinical Biochemistry

2005

Survival advantage of Hispanic patients initiating dialysis in the United States is modified by race.
Murthy BV, Molony DA, Stack AG
Journal of the American Society of Nephrology : JASN DOI: 10.1681/ASN.2004080627

2005

Association of physical activity with mortality in the US dialysis population.
Stack AG, Molony DA, Rives T, Tyson J, Murthy BV
American journal of kidney diseases : the official journal of the National Kidney Foundation

2005

Association of patient autonomy with increased transplantation and survival among new dialysis patients in the United States.
Stack AG, Martin DR
American journal of kidney diseases : the official journal of the National Kidney Foundation

2003

Impact of timing of nephrology referral and pre-ESRD care on mortality risk among new ESRD patients in the United States.
Stack AG
American journal of kidney diseases : the official journal of the National Kidney Foundation DOI: 10.1053/ajkd.2003.50038

2003

Mortality differences by dialysis modality among incident ESRD patients with and without coronary artery disease.
Ganesh SK, Hulbert-Shearon T, Port FK, Eagle K, Stack AG
Journal of the American Society of Nephrology : JASN

2002

Clinical correlates and mortality impact of left ventricular hypertrophy among new ESRD patients in the United States.
Stack AG, Saran R
American journal of kidney diseases : the official journal of the National Kidney Foundation DOI: 10.1053/ajkd.2002.36881

2002
2002

Impact of years of dialysis therapy on mortality risk and the characteristics of longer term dialysis survivors.
Okechukwu CN, Lopes AA, Stack AG, Feng S, Wolfe RA, Port FK
American journal of kidney diseases : the official journal of the National Kidney Foundation DOI: 10.1053/ajkd.2002.31403

2001

Association of elevated serum PO(4), Ca x PO(4) product, and parathyroid hormone with cardiac mortality risk in chronic hemodialysis patients.
Ganesh SK, Stack AG, Levin NW, Hulbert-Shearon T, Port FK
Journal of the American Society of Nephrology : JASN

2001

A cross-sectional study of the prevalence and clinical correlates of congestive heart failure among incident US dialysis patients.
Stack AG, Bloembergen WE
American journal of kidney diseases : the official journal of the National Kidney Foundation DOI: 10.1053/ajkd.2001.28588

2000