Prof. Andreas Grabrucker

Romina Coelho; Hélio Faustino; Chiara A. De Benedictis; Ann Katrin Sauer; António J. Figueira; Andreas M. Grabrucker; Cláudio M. Gomes (2024) Secondary Modification of S100B Influences Anti Amyloid-β Aggregation Activity and Alzheimer's Disease Pathology. International Journal Of Molecular Sciences

Ross A.M.;Cahalane R.M.;Walsh D.R.;Grabrucker A.M.;Marcar L.;Mulvihill J.J.E. (2023) Identification of Nanoparticle Properties for Optimal Drug Delivery across a Physiological Cell Barrier. Pharmaceutics

Vitrac A.;Leblond C.S.;Rolland T.;Cliquet F.;Mathieu A.;Maruani A.;Delorme R.;Schön M.;Grabrucker A.M.;van Ravenswaaij-Arts C.;Phelan K.;Tabet A.C.;Bourgeron T. (2023) Dissecting the 22q13 region to explore the genetic and phenotypic diversity of patients with Phelan-McDermid syndrome. European Journal Of Medical Genetics

Pandey M.K.;Grabrucker A.M.;Mehta S.Q. (2023) Editorial: Autism spectrum disorders and metal dyshomeostasis, volume II. Frontiers In Molecular Neuroscience

Hill-Yardin E.L.;Grabrucker A.M.;Franks A.E. (2023) Editorial: Interactions of the nervous system with bacteria, volume II. Frontiers In Neuroscience

Indika N.L.R.;Frye R.E.;Rossignol D.A.;Owens S.C.;Senarathne U.D.;Grabrucker A.M.;Perera R.;Engelen M.P.K.J.;Deutz N.E.P. (2023) The Rationale for Vitamin, Mineral, and Cofactor Treatment in the Precision Medical Care of Autism Spectrum Disorder. Personalized Medicine

Philip R.K.;Romeih E.;Bailie E.;Daly M.;McGourty K.D.;Grabrucker A.M.;Dunne C.P.;Walker G. (2023) Exclusive Human Milk Diet for Extremely Premature Infants: A Novel Fortification Strategy That Enhances the Bioactive Properties of Fresh, Frozen, and Pasteurized Milk Specimens. Breastfeeding medicine : the official journal of the Academy of Breastfeeding Medicine :279-290

Matuleviciene A.;Siauryte K.;Kuiper E.;Grabrucker A.M. (2023) Consensus recommendations on chewing, swallowing and gastrointestinal problems in Phelan-McDermid syndrome. European Journal Of Medical Genetics

Dudzi¿ska E.;Grabrucker A.M.;Kwiatkowski P.;Sitarz R.;Sienkiewicz M. (2023) The Importance of Visceral Hypersensitivity in Irritable Bowel Syndrome¿Plant Metabolites in IBS Treatment. Pharmaceuticals

Blazewicz A.;Grabrucker A.M. (2023) Metal Profiles in Autism Spectrum Disorders: A Crosstalk between Toxic and Essential Metals. International Journal Of Molecular Sciences

van Eeghen A.M.;Gaasterland C.M.W.;Haneveld M.J.K.;van Eeghen A.M.;Stemkens D.;Fernández-Fructuoso J.R.;Maruani A.;Hadzsiev K.;van Balkom I.D.C.;Alhambra N.;Anderlid B.M.;Andres S.;Aten E.;Guedes R.B.;Bonaglia M.C.;Bourgeron T.;Burdeus-Olavarrieta M.;Carbin M.J.;Kuiper E.;Cooke J.;Damstra R.J.;de Coo I.F.M.;Di Domenico S.;Evans D.G.;Fernández-Fructuoso J.R.;Grabrucker A.M.;Gunnarson C.;Hennekam R.C.;Jesse S.;Kant S.G.;Koza S.A.;van Ravenswaaij-Arts C.M.A.;Walinga M.;Landlust A.M.;van Ravenswaaij-Arts C.M.A.;Landlust A.M.;Lapunzina P.;Nevado J.;Lapunzina P.;Nevado J.;Lapunzina P.;Nevado J.;Loth E.;Mansour S.;Maruani A.;Mattina T.;Matulevičienė A.;Šiaurytė K.;Parker S.;Robert S.;Sala C.;Verpelli C.;San José Cáceres A.;Schön M.;Stemkens D.;Stiefsohn D.;Swillen A.;Tabet A.C.;Toro R.;Turner A.;van Balkom I.D.C.;van Buggenhout G.;van Eeghen A.M.;van Weering S.;Vignes S.;Vogels A.;Vyshka K.;Hugon A. (2023) Consensus recommendations on organization of care for individuals with Phelan-McDermid syndrome. European Journal Of Medical Genetics

Stanton J.E.;Grabrucker A.M. (2023) The use of organoids in food research. Current Opinion In Food Science

Pandey, MK;Grabrucker, AM;Mehta, SQ;Harvey, RJ (2022) Editorial: Autism Spectrum Disorders and Metal Dyshomeostasis. LAUSANNE Frontiers In Molecular Neuroscience

Azevedo L.;Serafim M.S.M.;Maltarollo V.G.;Grabrucker A.M.;Granato D. (2022) Atherosclerosis fate in the era of tailored functional foods: Evidence-based guidelines elicited from structure- and ligand-based approaches. Trends In Food Science & Technology :75-89

Sauer A.K.;Hagmeyer S.;Grabrucker A.M. (2022) Prenatal Zinc Deficient Mice as a Model for Autism Spectrum Disorders. International Journal Of Molecular Sciences

Grabrucker A.M. (2022) Non-Genetic Modifiers of Synaptic Plasticity and Neurotransmission in the Central Nervous System (CNS) in Health and Disease. International Journal Of Molecular Sciences

Harishkumar R.;Hans S.;Stanton J.E.;Grabrucker A.M.;Lordan R.;Zabetakis I. (2022) Targeting the Platelet-Activating Factor Receptor (PAF-R): Antithrombotic and Anti-Atherosclerotic Nutrients. Nutrients

De Benedictis C.A.;Trame S.;Rink L.;Grabrucker A.M. (2022) Prevalence of low dietary zinc intake in women and pregnant women in Ireland. Irish journal of medical science

Malijauskaite S.;Sauer A.K.;Hickey S.E.;Franzoni M.;Grabrucker A.M.;McGourty K. (2022) Identification of the common neurobiological process disturbed in genetic and non-genetic models for autism spectrum disorders. Cellular And Molecular Life Sciences

Duskey J.T.;Rinaldi A.;Ottonelli I.;Caraffi R.;De Benedictis C.A.;Sauer A.K.;Tosi G.;Vandelli M.A.;Ruozi B.;Grabrucker A.M. (2022) Glioblastoma Multiforme Selective Nanomedicines for Improved Anti-Cancer Treatments. Pharmaceutics

De Benedictis, CA;Trame, S;Rink, L;Grabrucker, AM (2022) Prevalence of low dietary zinc intake in women and pregnant women in Ireland. LONDON Irish journal of medical science

Hans S.;Stanton J.E.;O’Connor E.M.;Grabrucker A.M. (2022) Zinc Supplementation in Health and Disease. Trace Metals: Sources, Applications And Environmental Implications :1-29

Hans S.;Karadimou A.;Mulvihill J.J.E.;Grabrucker A.M.;Zabetakis I. (2022) The Role of Dietary Lipids in Cognitive Health: Implications for Neurodegenerative Disease. Biomedicine

Sauer, AK;Malijauskaite, S;Meleady, P;Boeckers, TM;McGourty, K;Grabrucker, AM (2022) Zinc is a key regulator of gastrointestinal development, microbiota composition and inflammation with relevance for autism spectrum disorders. BASEL : SPRINGER BASEL AG Cellular And Molecular Life Sciences

Romero-Aguirregomezcorta, J;Laguna-Barraza, R;Fernandez-Gonzalez, R;Stiavnicka, M;Ward, F;Cloherty, J;McAuliffe, D;Larsen, PB;Grabrucker, AM;Gutierrez-Adan, A;Newport, D;Fair, S (2021) Sperm selection by rheotaxis improves sperm quality and early embryo development. BRISTOL : BIOSCIENTIFICA LTD Reproduction :343-352

Daini, E;Hagmeyer, S;De Benedictis, CA;Cristovao, JS;Bodria, M;Ross, AM;Raab, A;Boeckers, TM;Feldmann, J;Gomes, CM;Zoli, M;Vilella, A;Grabrucker, AM (2021) S100B dysregulation during brain development affects synaptic SHANK protein networks via alteration of zinc homeostasis. LONDON : SPRINGERNATURE Translational Psychiatry

Hill-Yardin, EL;Grabrucker, AM;Franks, AE;Luna, RA;Monif, M (2021) Editorial: Interactions of the Nervous System With Bacteria. LAUSANNE Frontiers In Neuroscience

De Benedictis, CA;Haffke, C;Hagmeyer, S;Sauer, AK;Grabrucker, AM (2021) Expression Analysis of Zinc Transporters in Nervous Tissue Cells Reveals Neuronal and Synaptic Localization of ZIP4. BASEL : MDPI International Journal Of Molecular Sciences

Stanton JE; Malijauskaite S; McGourty K; Grabrucker AM (2021) The Metallome as a Link Between the "Omes" in Autism Spectrum Disorders. n/a Frontiers In Molecular Neuroscience :n/a-n/a

Sauer A.K.;Dooley L.;Vaughan A.;Grabrucker A.M. (2021) Altered gut-brain signaling in autism spectrum disorders-from biomarkers to possible intervention strategies. Neural Engineering Techniques For Autism Spectrum Disorder: Volume 1: Imaging And Signal Analysis :127-149

Grabrucker S;Pagano J;Schweizer J;Urrutia-Ruiz C;Schön M;Thome K;Ehret G;Grabrucker AM;Zhang R;Hengerer B;Bockmann J;Verpelli C;Sala C;Boeckers TM; (2021) Activation of the medial preoptic area (MPOA) ameliorates loss of maternal behavior in a Shank2 mouse model for autism.. Embo Journal

Malijauskaite S.;Mulvihill J.J.E.;Grabrucker A.M.;McGourty K. (2021) IPSC-derived intestinal organoids and current 3D intestinal scaffolds. Ipscs In Tissue Engineering :293-327

Lutz AK;Pfaender S;Incearap B;Ioannidis V;Ottonelli I;Föhr KJ;Cammerer J;Zoller M;Higelin J;Giona F;Stetter M;Stoecker N;Alami NO;Schön M;Orth M;Liebau S;Barbi G;Grabrucker AM;Delorme R;Fauler M;Mayer B;Jesse S;Roselli F;Ludolph AC;Bourgeron T;Verpelli C;Demestre M;Boeckers TM; (2020) Autism-associated SHANK3 mutations impair maturation of neuromuscular junctions and striated muscles.. Science Translational Medicine

DeBenedictis CA;Raab A;Ducie E;Howley S;Feldmann J;Grabrucker AM; (2020) Concentrations of Essential Trace Metals in the Brain of Animal Species-A Comparative Study.. Brain Sciences

Oddone N, Boury F, Garcion E, Grabrucker AM, Del Carmen Martinez M, Da F, Janaszewska A, Forni F, Vandelli MA, Tosi G, Ruozi B, Duskey JT (2020) Synthesis, Characterization, and In Vitro Studies of an Reactive Oxygen Species (ROS)-Responsive Methoxy Polyethylene Glycol-Thioketal- Melphalan Prodrug for Glioblastoma Treatment. Frontiers In Pharmacology

Mulvihill J.;Cunnane E.;Ross A.;Duskey J.;Tosi G.;Grabrucker A. (2020) Drug delivery across the blood-brain barrier: recent advances in the use of nanocarriers. Nanomedicine (London, England) :205-214

Ross A.M.;Kennedy T.;McNulty D.;Leahy C.I.;Walsh D.R.;Murray P.;Grabrucker A.M.;Mulvihill J.J.E. (2020) Comparing nanoparticles for drug delivery: The effect of physiological dispersion media on nanoparticle properties. Materials Science & Engineering C-Materials For Biological Applications

Ross A.M.;Grabrucker A.M.;McGourty K.D.;Mulvihill J.J.E. (2020) Metallic-based nanocarriers: methods employed in nanoparticle characterization and assessing the interaction with the blood–brain barrier. Advances And Avenues In The Development Of Novel Carriers For Bioactives And Biological Agents :255-282

Sauer A.;Grabrucker A. (2019) Zinc Deficiency During Pregnancy Leads to Altered Microbiome and Elevated Inflammatory Markers in Mice. Frontiers In Neuroscience

Sauer A.;Bockmann J.;Steinestel K.;Boeckers T.;Grabrucker A. (2019) Altered Intestinal Morphology and Microbiota Composition in the Autism Spectrum Disorders Associated SHANK3 Mouse Model. International Journal Of Molecular Sciences

Pederzoli F.;Ruozi B.;Duskey J.;Hagmeyer S.;Sauer A.;Grabrucker S.;Coelho R.;Oddone N.;Ottonelli I.;Daini E.;Zoli M.;Vandelli M.;Tosi G.;Grabrucker A. (2019) Nanomedicine against Aβ aggregation by β–sheet breaker peptide delivery: In vitro evidence. Pharmaceutics

Oddone N.;Pederzoli F.;Duskey J.;De Benedictis C.;Grabrucker A.;Forni F.;Angela Vandelli M.;Ruozi B.;Tosi G. (2019) ROS-responsive “smart” polymeric conjugate: Synthesis, characterization and proof-of-concept study. International journal of pharmaceutics

Hagmeyer S.;Romão M.;Cristóvão J.;Vilella A.;Zoli M.;Gomes C.;Grabrucker A. (2019) Distribution and relative abundance of S100 proteins in the brain of the APP23 Alzheimer’s disease model mice. Frontiers In Neuroscience

Ross AM;Mc Nulty D;O'Dwyer C;Grabrucker AM;Cronin P;Mulvihill JJE; (2019) Standardization of research methods employed in assessing the interaction between metallic-based nanoparticles and the blood-brain barrier: Present and future perspectives.. Journal Of Controlled Release

Schoen M.;Asoglu H.;Bauer H.;Müller H.;Abaei A.;Sauer A.;Zhang R.;Song T.;Bockmann J.;Kassubek J.;Rasche V.;Grabrucker A.;Boeckers T. (2019) Shank3 Transgenic and Prenatal Zinc-Deficient Autism Mouse Models Show Convergent and Individual Alterations of Brain Structures in MRI. Frontiers In Neural Circuits :-6

Belletti, D; Grabrucker, AM; Pederzoli, F; Menrath, I; Vandelli, MA; Tosi, G; Duskey, TJ; Forni, F; Ruozi, B; (2018) Hybrid nanoparticles as a new technological approach to enhance the delivery of cholesterol into the brain. International journal of pharmaceutics :300-310

Grabrucker, S,Haderspeck, JC,Sauer, AK,Kittelberger, N,Asoglu, H,Abaei, A,Rasche, V,Schon, M,Boeckers, TM,Grabrucker, AM (2018) Brain Lateralization in Mice Is Associated with Zinc Signaling and Altered in Prenatal Zinc Deficient Mice That Display Features of Autism Spectrum Disorder. Frontiers In Molecular Neuroscience

Hagmeyer, S,Cristovao, JS,Mulvihill, JJE,Boeckers, TM,Gomes, CM,Grabrucker, AM (2018) Zinc Binding to S100B Affords Regulation of Trace Metal Homeostasis and Excitotoxicity in the Brain. Frontiers In Molecular Neuroscience

Hagmeyer S;Sauer AK;Grabrucker AM; (2018) Prospects of Zinc Supplementation in Autism Spectrum Disorders and Shankopathies Such as Phelan McDermid Syndrome.. Frontiers In Synaptic Neuroscience

Vilella, A; Belletti, D; Sauer, AK; Hagmeyer, S; Sarowar, T; Masoni, M; Stasiak, N; Mulvihill, JJE; Ruozi, B; Forni, F; Vandelli, MA; Tosi, G; Zoli, M; Grabrucker, AM (2017) Reduced plaque size and inflammation in the APP23 mouse model for Alzheimer's disease after chronic application of polymeric nanoparticles for CNS targeted zinc delivery.. Journal Of Trace Elements In Experimental Medicine

Sauer, AK,Pfaender, S,Hagmeyer, S,Tarana, L,Mattes, AK,Briel, F,Kury, S,Boeckers, TM,Grabrucker, AM (2017) Characterization of zinc amino acid complexes for zinc delivery in vitro using Caco-2 cells and enterocytes from hiPSC. Biometals :643-661

Sarowar, T; Grabrucker, S; Boeckers, TM; Grabrucker, AM (2017) Object phobia and altered RhoA signaling in amygdala of mice lacking RICH2. Frontiers In Neuroscience

Ruozi, B; Belletti, D; Pederzoli, F; Masoni, M; Keller, J; Ballestrazzi, A; Vandelli, MA; Tosi, G; Grabrucker, AM (2017) Novel Curcumin loaded nanoparticles engineered for Blood-Brain Barrier crossing and able to disrupt Abeta aggregates. International Journal Of Pharmaceutics

Ardiles, AO; Grabrucker, AM; Scholl, FG; Rudenko, G; Borsello, T (2017) Molecular and Cellular Mechanisms of Synaptopathies. Neural plasticity :1-3

Pfaender, S; Sauer, AK; Hagmeyer, S; Mangus, K; Linta, L; Liebau, S; Bockmann, J; Huguet, G; Bourgeron, T; Boeckers, TM; Grabrucker, AM (2017) Zinc deficiency and low enterocyte zinc transporter expression in human patients with autism related mutations in SHANK3. Scientific Reports

Küry, S; van Woerden, GM; Besnard, T; Proietti Onori, M; Latypova, X; Towne, MC; Cho, MT; Prescott, TE; Ploeg, MA; Sanders, S; Stessman, HAF; Pujol, A; Distel, B; Robak, LA; Bernstein, JA; Denommé-Pichon, AS; Lesca, G; Sellars, EA; Berg, J; Carré, W; Busk, ØL; van Bon, BWM; Waugh, JL; Deardorff, M; Hoganson, GE; Bosanko, KB; Johnson, DS; Dabir, T; Holla, ØL; Sarkar, A; Tveten, K; de Bellescize, J; Braathen, GJ; Terhal, PA; Grange, DK; van Haeringen, A; Lam, C; Mirzaa, G; Burton, J; Bhoj, EJ; Douglas, J; Santani, AB; Nesbitt, AI; Helbig, KL; Andrews, MV; Begtrup, A; Tang, S; van Gassen, KLI; Juusola, J; Foss, K; Enns, GM; Moog, U; Hinderhofer, K; Paramasivam, N; Lincoln, S; Kusako, BH; Lindenbaum, P; Charpentier, E; Nowak, CB; Cherot, E; Simonet, T; Ruivenkamp, CAL; Hahn, S; Brownstein, CA; Xia, F; Schmitt, S; Deb, W; Bonneau, D; Nizon, M; Quinquis, D; Chelly, J; Rudolf, G; Sanlaville, D; Parent, P; Gilbert-Dussardier, B; Toutain, A; Sutton, VR; Thies, J; Peart-Vissers, LELM; Boisseau, P; Vincent, M; Grabrucker, AM; Dubourg, C; Tan, WH; Verbeek, NE; Granzow, M; Santen, GWE; Shendure, J; Isidor, B; Pasquier, L; Redon, R; Yang, Y; State, MW; Kleefstra, T; Cogné, B; Petrovski, S; Retterer, K; Eichler, EE; Rosenfeld, JA; Agrawal, PB; Bézieau, S; Odent, S; Elgersma, Y; Mercier, S (2017) De Novo Mutations in Protein Kinase Genes CAMK2A and CAMK2B Cause Intellectual Disability. American Journal Of Human Genetics :768-788

Sarowar, T; Grabrucker, AM (2016) Actin-Dependent Alterations of Dendritic Spine Morphology in Shankopathies. Neural plasticity

Grabrucker, S; Boeckers, TM; Grabrucker, AM (2016) Gender Dependent Evaluation of Autism like Behavior in Mice Exposed to Prenatal Zinc Deficiency. Frontiers In Behavioral Neuroscience

Sarowar, T; Grabrucker, S; Föhr, K; Mangus, K; Eckert, M; Bockmann, J; Boeckers, TM; Grabrucker, AM (2016) Enlarged dendritic spines and pronounced neophobia in mice lacking the PSD protein RICH2. Molecular Brain

Sarowar, T; Chhabra, R; Vilella, A; Boeckers, TM; Zoli, M; Grabrucker, AM (2016) Activity and circadian rhythm influence synaptic Shank3 protein levels in mice. Journal Of Neurochemistry :887-895

Belletti, D; Grabrucker, AM; Pederzoli, F; Menrath, I; Cappello, V; Vandelli, MA; Forni, F; Tosi, G; Ruozi, B (2016) EXPLOITING THE VERSATILITY OF CHOLESTEROL IN NANOPARTICLES FORMULATION. International Journal Of Pharmaceutics :331-340

Pfaender, S; Föhr, K; Lutz, AK; Putz, S; Achberger, K; Linta, L; Liebau, S; Boeckers, TM; Grabrucker, AM (2016) Cellular Zinc Homeostasis Contributes to Neuronal Differentiation in Human Induced Pluripotent Stem Cells. Neural plasticity

Heiliger, E; Osmanagic, A; Haase, H; Golenhofen, N; Grabrucker, AM; Weth, A; Baumgartner, W (2015) N-Cadherin-mediated cell adhesion is regulated by extracellular Zn(2+). Metallomics :355-362

Hagmeyer, S; Mangusm K; Boeckers, TM; Grabrucker, AM (2015) Effects of trace metal profiles characteristic for autism on synapses in cultured neurons. Neural plasticity

Chhabra, R; Ruozi, B; Vilella, A; Belletti, D; Mangus, K; Pfaender, S; Sarowar, T; Boeckers, TM; Zoli, M; Forni, F; Vandelli, MA; Tosi, G; Grabrucker, AM (2015) Application of Polymeric Nanoparticles for CNS Targeted Zinc Delivery In Vivo. Cns & Neurological Disorders-Drug Targets :1041-1053

Chhabra, R; Tosi, G; Grabrucker, AM (2015) Emerging Use of Nanotechnology in the Treatment of Neurological Disorders. Current Pharmaceutical Design :3111-3130

Vela, G; Stark, P; Socha, M; Sauer, AK; Hagmeyer, S; Grabrucker, AM (2015) Zinc in gut-brain interaction in autism and neurological disorders. Neural plasticity

Hagmeyer, S; Haderspeck, JC; Grabrucker, AM (2014) Behavioral impairments in animal models for zinc deficiency. Frontiers In Behavioral Neuroscience

Grabrucker, S; Proepper, C; Mangus, K; Eckert, M; Chhabra, R; Schmeisser, MJ; Boeckers, TM; Grabrucker, AM. (2014) The PSD protein ProSAP2/Shank3 displays synapto-nuclear shuttling which is deregulated in a schizophrenia-associated mutation. Experimental Neurology :126-137

Baecker, T; Mangus, K; Pfaender, S; Chhabra, R; Boeckers, TM; Grabrucker, AM (2014) Loss of COMMD1 and copper overload disrupt zinc homeostasis and influence an autism-associated pathway at glutamatergic synapses. Biometals :715-730

Chhabra, R; Grabrucker, AM; Veratti, P; Belletti, D; Boeckers, TM; Vandelli, MA; Forni, F; Tosi, G; Ruozi, B (2014) Characterization of lysosome-destabilizing DOPE/PLGA nanoparticles designed for cytoplasmic drug release. International Journal Of Pharmaceutics :349-357

Pfaender, S; Grabrucker, AM (2014) Characterization of biometal profiles in neurological disorders. Metallomics :960-977

Vilella, A; Tosi, G; Grabrucker, AM; Ruozi, B; Belletti, D; Vandelli, MA; Boeckers, TM; Forni, F; Zoli, M (2014) Insight on the fate of CNS-targeted nanoparticles. Part I: Rab5-dependent cell-specific uptake and distribution. Journal Of Controlled Release :195-201

Grabrucker, S; Jannetti, L; Eckert, M; Gaub, S; Chhabra, R; Pfaender, S; Mangus, K; Reddy, PP; Rankovic, V; Schmeisser, MJ; Kreutz, MR; Ehret, G; Boeckers, TM; Grabrucker, AM (2014) Zinc deficiency dysregulates the synaptic ProSAP/Shank scaffold and might contribute to autism spectrum disorders. Brain :137-152

Tosi, G; Vilella, A; Chhabra, R; Schmeisser, MJ; Boeckers, TM; Ruozi, B; Vandelli, MA; Forni, F; Zoli, M; Grabrucker, AM (2014) Insight on the fate of CNS-targeted nanoparticles. Part II: Intercellular neuronal cell-to-cell transport. Journal Of Controlled Release :90-107

Schmeisser, MJ; Kühl, SJ; Schoen, M; Beth, NH; Weis, TM; Grabrucker, AM; Kühl, M; Boeckers, TM (2013) The Nedd4-binding protein 3 (N4BP3) is crucial for axonal and dendritic branching in developing neurons. Neural Development

Arons, MH; Thynne, CJ; Grabrucker, AM; Li, D; Schoen, M; Cheyne, JE; Boeckers, TM; Montgomery, JM; Garner, CC (2012) Autism-associated mutations in ProSAP2/Shank3 impair synaptic transmission and neurexin-neuroligin-mediated transsynaptic signaling. Journal Of Neuroscience :14966-14978

Grabrucker, AM (2012) Grabrucker AM. Environmental factors in autism. Frontiers in psychiatry

Schmeisser, MJ; Ey, E; Wegener, S; Bockmann, J; Stempel, AV; Kuebler, A; Janssen, AL; Udvardi, PT; Shiban, E; Spilker, C; Balschun, D; Skryabin, BV; Dieck, St; Smalla, KH; Montag, D; Leblond, CS; Faure, P; Torquet, N; Le Sourd, AM; Toro, R; Grabrucker, AM; Shoichet, SA; Schmitz, D; Kreutz, MR; Bourgeron, T; Gundelfinger, ED; Boeckers, TM (2012) Autistic-like behaviours and hyperactivity in mice lacking ProSAP1/Shank2. Nature :256-260

Grabrucker, AM; Schmeisser, MJ; Udvardi, PT; Arons, M; Schoen, M; Woodling, NS; Andreasson, KI; Hof, PR; Buxbaum, JD; Garner, CC; Boeckers, TM (2011) Amyloid beta protein-induced zinc sequestration leads to synaptic loss via dysregulation of the ProSAP2/Shank3 scaffold. Molecular Neurodegeneration

Grabrucker, AM; Garner, CC; Boeckers, TM; Bondioli, L; Ruozi, B; Forni, F; Vandelli, MA; Tosi, G (2011) Development of novel Zn2+ loaded nanoparticles designed for cell-type targeted drug release in CNS neurons: in vitro evidences. Plos One :e17851-

Grabrucker, AM; Schmeisser, MJ; Schoen, M; Boeckers, TM (2011) Postsynaptic ProSAP/Shank scaffolds in the cross-hair of synaptopathies. Trends In Cell Biology :594-603

Grabrucker, AM; Knight, MJ; Proepper, C; Bockmann, J; Joubert, M; Rowan, M; Nienhaus, GU; Garner, CC; Bowie, JU; Kreutz, MR; Gundelfinger, ED; Boeckers, TM (2011) Concerted action of zinc and ProSAP/Shank in synaptogenesis and synapse maturation. Embo Journal :569-581

Grabrucker, AM; Vaida, B; Bockmann, J; Boeckers, TM (2009) Efficient targeting of proteins to post-synaptic densities of excitatory synapses using a novel pSDTarget vector system. Journal Of Neuroscience Methods :227-234

Vellanki, SH; Grabrucker, A; Liebau, S; Proepper, C; Eramo, A; Braun, V; Boeckers, T; Debatin, KM; Fulda, S (2009) Small-molecule XIAP inhibitors enhance gamma-irradiation-induced apoptosis in glioblastoma. Neoplasia :743-752

Grabrucker, A; Vaida, B; Bockmann, J; Boeckers, TM (2009) Synaptogenesis of hippocampal neurons in primary cell culture. Cell And Tissue Research :333-341

Schmeisser, MJ; Grabrucker, AM; Bockmann, J; Boeckers, TM (2009) ynaptic cross-talk between N-methyl-D-aspartate receptors and LAPSER1-beta-catenin at excitatory synapses. Journal Of Biological Chemistry :29146-29157