Biography

Sarah studied Chemistry in Trinity College Dublin were she was a Trinity Foundation Scholar and where she did a research masters on the synthesis of a family of Re (I) metal complexes and a study of their photophysical properties with Prof John Kelly. Her PhD in the University of Limerick focussed on the immobilization of enzymes onto novel mesoporous supports and their catalytic properties with Prof Edmond Magner, Prof Kieran Hodnett and Dr Jakki Cooney. She secured a Marie Curie Outgoing International Fellowship to work with Prof Robert Langer in MIT, USA. There she developed in situ crosslinkable hydrogel systems for cartilage regeneration and drug delivery and she also studied the biocompatibility (in vivo and in vitro) of micro- and nano- mesoporous silica particles. After this fellowship, Sarah worked in Waterford Institute of Technology on the identification of the mechanisms and causes of tablet splitting within the Genzyme Ireland facility. Since November 2011, Sarah has been a lecturer in Chemistry in the Department of Chemical Sciences and a researcher in the Bernal Institute in the University of Limerick. She is a principal investigator in the Science Foundation Ireland Research Centre for Pharmaceuticals (SSPC) since 2013.

Research Interests


The Hudson group focuses on the manipulation of the physicochemical properties of small and large active molecules to improve their stability, solubility and dissolution rates with the ultimate goal of improving the bioavailability of active pharmaceutical ingredients. They explore the solution and solid state behaviour of these molecules both during formulation/manufacture into medicines and in biorelevant environments. Their research focuses on the thermodynamics behind aggregation, crystallisation and precipitation in a range of solvents and bio relevant media and develops formulations and structures to control this solution/solid state behaviour.

Current Postdoctoral researchers:
Dr Jhimli Paulguin
Dr Poonam Ratrey
Dr Shasha Jin

Current PhD students:
Mariana Silva (Marie Curie ITN, Janssen)
Amabille Kloc (Marie Curie ITN, TUD, Janssen)
Peuli Ghosh (SFI, SSPC)
Parth Joshi (PMTC, Allergen)
Mariana Diniz (SFI, SSPC)
Marta Bergillos (SFI, SSPC)
Harsh Barua (SFI, SSPC)
Camila Viera (SFI, New Frontiers)
Mateo Flores Naranjo (SFI, New Frontiers)
Francisco Duarte (IRC)
Sara Fatima (SFI, co-supervised with Jennifer Cookman)

Former PhD students:
Dr Teresa Tierney (IRCSET, SSPC)
Dr Raquel Arribas Bueno (SFI SSPC)
Dr Pauric Bannigan (SFI CDA)
Dr Vivek Verma (SFI SSPC)
Dr Katalin Bodnar (SFI SSPC)
Dr Ajay Kumar (SFI, SSPC)
Dr Michele Dully (IRC, COOK Medical)
Dr James Flynn (SFI, CDA)
Dr Sally Ryan (SFI, Curam)
Dr Miriama Ceresnakova (IRC, COOK Medical)
Dr Aoibhin Ryan (IRC)

Former Masters students:
Sarah Mallen (SFI CDA)
Tracey Carroll (Sanofi Genzyme)

Former Postdocs:
Dr Gesmi Mikovich (SFI CDA)
Dr Edel Durack (SFI CDA)
Dr Aisling Lynch (SFI SSPC)
Dr Ajay Kumar (SFI, SSPC)
Dr Malgorzata Tecza (DTIF, EI)
Dr Pratikkumar Patel
Dr Promita Bhattacharjee
Dr Vinay Gedi

Professional Activities

Award

  • 2019 - Disruptive Technologies Award
  • 2019 - Marie Curie ITN EID
  • 2017 - SFI Infrastructure Award
  • 2014 - SFI Career Development Award
  • 2013 - MSSI Innovation Award
  • 2013 - PI in the Synthesis and Solid State Pharmaceutical Centre
  • 2013 - Academic Partner in Enterprise Ireland Commercialisation Grant
  • 2012 - Principal Supervisor of an IRCSET Student
  • 2012 - Fast Moving Front paper
  • 2007 - Best Post-graduate Web of Science Journal Publication
  • 2006 - Marie Curie Outgoing International Fellowship
  • 2005 - BOC Gases Post Graduate Bursary
  • 1997 - Foundation Scholar of Trinity College Dublin

Association

  • 2014 Member, Marie Curie Alumni Association

Education

  • 2013 University of Limerick - Diploma
  • 2006 University of Limerick - PhD
  • 2000 Trinity College Dublin - Masters by research
  • 1999 Trinity College Dublin - BA (Mod)

Outreach

  • Volunteered at the St Vincent de Paul grind school in Moyross 2011-2012
  • School placement tutor for training education students 2012-present

Publications

Peer Reviewed Journals

2011

A Prototype Antifungal Contact Lens

Ciolino, JB; Hudson, SP; Mobbs, AN; Hoare, TR; Iwata, NG; Fink, GR; Kohane, DS (2011) A Prototype Antifungal Contact Lens. Investigative Ophthalmology & Visual Science :6286-6291

2008

Proteins in mesoporous silicates.

Hudson, S; Cooney, J; Magner, E (2008) Proteins in mesoporous silicates.. Angewandte Chemie-International Edition In English :8582-8594

2003

The photophysics of fac-[Re(CO)3(dppz)(py)]+ in CH3CN: a comparative picosecond flash photolysis, transient infrared, transient resonance Raman and density functional theoretical study.

Dyer J, Blau WJ, Coates CG, Creely CM, Gavey JD, George MW, Grills DC, Hudson S, Kelly JM, Matousek P, McGarvey JJ, McMaster J, Parker AW, Towrie M, Weinstein JA (2003) The photophysics of fac-[Re(CO)3(dppz)(py)]+ in CH3CN: a comparative picosecond flash photolysis, transient infrared, transient resonance Raman and density functional theoretical study.. Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology :542-554

Books

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Book Chapters

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Edited Books

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Other Journals

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Conference Publications

2009

33rd Annual MSI Meeting

Tanner D. A. Nakahara S. Hudson S. Magner E. Redington W. Hodnett K. (2009) 33rd Annual MSI Meeting.

2005

Europacat

Hudson, S., Hodnett, B.K., Cooney, J., and Magner, E. (2005) Europacat. :*-*

Conference Contributions

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Published Reports

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Editorials

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Book Reviews

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Other Publications