Dr. George Barreto
Biography
Dr. Barreto earned his PhD in Neuroscience (2009) from the Universidad Complutense Madrid (Spain) studying the effects of neurosteroids on reactive glia with traumatic brain injury under the supervision of Professor Luis Miguel Garcia-Segura. His Post-doctoral training in Neuroscience at Stanford University School of Medicine (2009-2011), under the mentorship of Professor Rona G. Giffard, focused on addressing the role of astrocytes activation following stroke and enhance astrocytic functions targeting neuronal protection. With the collaboration of Professor Carla J. Shatz, also from Stanford, Dr Barreto and cols discovered that both PirB receptor and MHCI molecules are involved in the physiopathology of stroke by regulating astroglia activation and behavioural outcome. Nowadays he is a Lecturer in Cell Biology/Immunology in the Department of Biological Sciences at the University of Limerick (Ireland), is a member of the Bernal Institute and Health Research Institute from the same University.Associate Editor, Frontiers in Aging Neuroscience
Associate Editor, Frontiers in Neurology/Neurotrauma
Associate Editor, Frontiers in Neuroscience
Associate Editor, Frontiers in Nutrition
Associate Editor, Nutritional Neuroscience
Academic Editor, Plos One
Associate Editor, BMC Neurology
Consulting Editor, Pharmacological Research
Current Students
2019 Oscar Hidalgo Lanussa. Ph.D. in Biological Sciences
2019 Angie Garzón. M.Sc in Neurosciences
Students supervised
2019 Yeimy González. Ph.D. in Biological Sciences
2018 Eliana Báez. Ph.D. in Biological Sciences
2017 Ricardo Cabezas. Ph.D. in Biological Sciences
2016 Marco Ávila-Rodriguez. Ph.D. in Biological Sciences
2016 Oscar Hidalgo Lanussa. M.Sc in Biological Sciences
2016 Natalia Areiza. M.Sc in Nutrition Sciences
Research Interests
We are keen to understand how androgens and estrogens affect brain functions, particularly on how these hormones control mitochondrial functions in the healthy and diseased brain with life span in a sex dimorphic manner. We are currently investigating these research areas:- The effects of synthetic hormones (e.g. tibolone) on mitochondria metabolism.
- Hormonal signaling affecting cellular outcome, and how important this is for mitochondrial respiration under neurological diseases in presence or absence of hormones.
- Dysregulation of lipid metabolism within mitochondria and neuroimmune response following brain damage.
- Drug design and development of new drugs analogues to hormones for targeting mitochondria
Research Areas:
Neuroendocrinology
Neurobiology
Neurosciences
Key Terms:
Mitochondria
Biological Sex differences
Brain
Glial Cells
Neurosteroids
Neurodegenerative Diseases
Hormones
Neuroinflammation
Traumatic brain injury
Professional Activities
Committee
- 2019 Grants Reviewer (Expert). National Science Centre Poland, Poland,
- 2019 Grants Reviewer (Expert). Ministery of Science, Technology and Innovation (Foncyt), Programme PICT, Argentina,
- 2019 Evaluation Committee (Expert). H2020-MSCA-IF-2019, European Commission,
- 2018 Evaluation Committee. MFP-COFUND PhD fellowships, Universitat Rovira i Virgili, Tarragona, Spain,
- 2018 Grant Review. National Research Council (Colciencias),
- 2018 Evaluation Committee. Postdoctoral Fellowship Program. National Research Council (Colciencias),
- 2018 Evaluation Committee (Expert). H2020-MSCA-IF-2018, European Commission,
- 2017 Grant Review. Career Development Award, Human Frontier Science Program (HFSP), France,
- 2017 Evaluation Committee. Postdoctoral Fellowship Program. National Research Council (Colciencias),
- 2017 Book proposal reviewer. Title: Neuroprotection in Autism, Schizophrenia & Alzheimer's Disease,
- 2016 Grant Review. National Research Council (Colciencias),
- 2015 Grant Review. National Research Council (Colciencias),
- 2014 Ad-Hoc and Evaluation Committee. Grants Program,
- 2014 Evaluation Committee Grant Review. Parkinson UK,
- 2014 Grant Review. National Research Council (Colciencias),
Employment
- 2009 Stanford University School of Medicine - Post-Doctoral Fellow in Neurosciences
Award
- 2009 - Postdoctoral Fellowship
- 2005 - WERC/FENS PhD Fellowship
Education
- 2009 Complutense University Madrid - PhD in Biological Sciences
Language
- Portuguese
- Spanish
Association
- Member, International Brain Research Organization
- Full member, International Society for Neurochemistry
- Full member, Federation of European Neuroscience Societies
- Full member, European Society of Neurochemistry
Research Collaborators
- Luis Miguel Garcia- Segura - International Collaboration Type -Spain -Cajal Institute, Madrid, Spain
- Roberto C. Melcangi - International Collaboration Type - University of Milan -Italy
- Valentina Echeverria - Joint Publication -Chile -Universidad San Sebastián
- Janneth González - Joint Publication
Peer Reviewed Journals
Dissecting Sex-Related Cognition between Alzheimer's Disease and Diabetes: From Molecular Mechanisms to Potential Therapeutic Strategies.
Ashraf GM;Ebada MA;Suhail M;Ali A;Uddin MS;Bilgrami AL;Perveen A;Husain A;Tarique M;Hafeez A;Alexiou A;Ahmad A;Kumar R;Banu N;Najda A;Sayed AA;Albadrani GM;Abdel-Daim MM;Peluso I;Barreto GE; (2021) Dissecting Sex-Related Cognition between Alzheimer's Disease and Diabetes: From Molecular Mechanisms to Potential Therapeutic Strategies.. Oxidative Medicine And Cellular Longevity
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Common genes and pathways involved in the response to stressful stimuli by astrocytes: A meta-analysis of genome-wide expression studies.
González-Giraldo Y;Forero DA;Barreto GE;Aristizábal-Pachón A; (2021) Common genes and pathways involved in the response to stressful stimuli by astrocytes: A meta-analysis of genome-wide expression studies.. Genomics
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Brain lipidomics as a rising field in neurodegenerative contexts: Perspectives with Machine Learning approaches.
Castellanos DB;Martín-Jiménez CA;Rojas-Rodríguez F;Barreto GE;González J; (2021) Brain lipidomics as a rising field in neurodegenerative contexts: Perspectives with Machine Learning approaches.. Frontiers In Neuroendocrinology
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Biomolecular alterations in acute traumatic brain injury (TBI) using Fourier transform infrared (FTIR) imaging spectroscopy.
Rakib F;Al-Saad K;Ahmed T;Ullah E;Barreto GE;Md Ashraf G;Ali MHM; (2021) Biomolecular alterations in acute traumatic brain injury (TBI) using Fourier transform infrared (FTIR) imaging spectroscopy.. Spectrochimica Acta Part A-Molecular And Biomolecular Spectroscopy
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Apoptotic neurons and amyloid-beta clearance by phagocytosis in Alzheimer's disease: Pathological mechanisms and therapeutic outlooks.
Tajbakhsh A;Read M;Barreto GE;Ávila-Rodriguez M;Gheibi-Hayat SM;Sahebkar A; (2021) Apoptotic neurons and amyloid-beta clearance by phagocytosis in Alzheimer's disease: Pathological mechanisms and therapeutic outlooks.. European Journal Of Pharmacology
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Neural Stem Cell-Based Therapies and Glioblastoma Management: Current Evidence and Clinical Challenges.
Benmelouka AY;Munir M;Sayed A;Attia MS;Ali MM;Negida A;Alghamdi BS;Kamal MA;Barreto GE;Ashraf GM;Meshref M;Bahbah EI; (2021) Neural Stem Cell-Based Therapies and Glioblastoma Management: Current Evidence and Clinical Challenges.. International Journal Of Molecular Sciences
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Vitamin D Receptor Genetic Polymorphisms and the Risk of Multiple Sclerosis: A Systematic Review and Meta-Analysis
Mohammadi A, Azarnezhad A, Khanbabaei H, Izadpanah E, Abdollahzadeh R, Barreto GE, Sahebkar A (2020) Vitamin D Receptor Genetic Polymorphisms and the Risk of Multiple Sclerosis: A Systematic Review and Meta-Analysis. Steroids
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Nano-engineered nerolidol loaded lipid carrier delivery system attenuates cyclophosphamide neurotoxicity - Probable role of NLRP3 inflammasome and caspase-1.
Iqubal A;Syed MA;Najmi AK;Azam F;Barreto GE;Iqubal MK;Ali J;Haque SE; (2020) Nano-engineered nerolidol loaded lipid carrier delivery system attenuates cyclophosphamide neurotoxicity - Probable role of NLRP3 inflammasome and caspase-1.. Experimental Neurology
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Emerging Therapeutic Promise of Ketogenic Diet to Attenuate Neuropathological Alterations in Alzheimer's Disease.
Uddin MS;Kabir MT;Tewari D;Al Mamun A;Barreto GE;Bungau SG;Bin-Jumah MN;Abdel-Daim MM;Ashraf GM; (2020) Emerging Therapeutic Promise of Ketogenic Diet to Attenuate Neuropathological Alterations in Alzheimer's Disease.. Molecular Neurobiology
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Cotinine Enhances Fear Extinction and Astrocyte Survival by Mechanisms Involving the Nicotinic Acetylcholine Receptors Signaling
Oliveros-Matus P, Perez-Urrutia N, Alvarez-Ricartes N, Echeverria F, Barreto GE, Elliott J, Iarkov A, Echeverria V (2020) Cotinine Enhances Fear Extinction and Astrocyte Survival by Mechanisms Involving the Nicotinic Acetylcholine Receptors Signaling. Frontiers In Pharmacology
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Estrogen Signaling in Alzheimer's Disease: Molecular Insights and Therapeutic Targets for Alzheimer's Dementia
Uddin MS, Rahman MM, Jakaria M, Rahman MS, Hossain MS, Islam A, Ahmed M, Mathew B, Omar UM, Barreto GE, Ashraf GM (2020) Estrogen Signaling in Alzheimer's Disease: Molecular Insights and Therapeutic Targets for Alzheimer's Dementia. Molecular Neurobiology
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Advances in Astrocyte Computational Models: From Metabolic Reconstructions to Multi-omic Approaches.
González J;Pinzón A;Angarita-Rodríguez A;Aristizabal AF;Barreto GE;Martín-Jiménez C; (2020) Advances in Astrocyte Computational Models: From Metabolic Reconstructions to Multi-omic Approaches.. Frontiers In Neuroinformatics
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Molecular Mechanisms of ER Stress and UPR in the Pathogenesis of Alzheimer's Disease
Uddin MS, Tewari D, Sharma G, Kabir MT, Barreto GE, Bin-Jumah MN, Perveen A, Abdel-Daim MM, Ashraf GM (2020) Molecular Mechanisms of ER Stress and UPR in the Pathogenesis of Alzheimer's Disease. Molecular Neurobiology
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The neutrophil-to-lymphocyte ratio in Alzheimer's disease: Current understanding and potential applications.
Sayed A;Bahbah EI;Kamel S;Barreto GE;Ashraf GM;Elfil M; (2020) The neutrophil-to-lymphocyte ratio in Alzheimer's disease: Current understanding and potential applications.. Journal Of Neuroimmunology
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The potential of mitochondrial modulation by neuroglobin in treatment of neurological disorders.
Gorabi AM;Aslani S;Barreto GE;Báez-Jurado E;Kiaie N;Jamialahmadi T;Sahebkar A; (2020) The potential of mitochondrial modulation by neuroglobin in treatment of neurological disorders.. Free Radical Biology And Medicine
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The Role of Nuclear Factors as "Find-Me"/alarmin Signals and Immunostimulation in Defective Efferocytosis and Related Disorders
Tajbakhsh A, Rezaee M, Barreto GE, Moallem SA, Henney NC, Sahebkar A (2020) The Role of Nuclear Factors as "Find-Me"/alarmin Signals and Immunostimulation in Defective Efferocytosis and Related Disorders. International Immunopharmacology
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Exploring the Potential of Neuroproteomics in Alzheimer's Disease.
Uddin MS;Kabir MT;Jakaria M;Sobarzo-Sánchez E;Barreto GE;Perveen A;Hafeez A;Bin-Jumah MN;Abdel-Daim MM;Ashraf GM; (2020) Exploring the Potential of Neuroproteomics in Alzheimer's Disease.. Current Topics In Medicinal Chemistry
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Boosting the autophagy-lysosomal pathway by phytochemicals: A potential therapeutic strategy against Alzheimer's disease.
Nourbakhsh F;Read MI;Barreto GE;Sahebkar A; (2020) Boosting the autophagy-lysosomal pathway by phytochemicals: A potential therapeutic strategy against Alzheimer's disease.. Iubmb Life
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Revisiting the role of brain and peripheral Aβ in the pathogenesis of Alzheimer's disease
Uddin MS, Kabir MT, Tewari D, Mamun AA, Mathew B, Aleya L, Barreto GE, Bin-Jumah MN, Abdel-Daim MM, Ashraf GM (2020) Revisiting the role of brain and peripheral Aβ in the pathogenesis of Alzheimer's disease. Journal Of The Neurological Sciences
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Multifarious roles of mTOR signaling in cognitive aging and cerebrovascular dysfunction of Alzheimer's disease.
Uddin MS;Rahman MA;Kabir MT;Behl T;Mathew B;Perveen A;Barreto GE;Bin-Jumah MN;Abdel-Daim MM;Ashraf GM; (2020) Multifarious roles of mTOR signaling in cognitive aging and cerebrovascular dysfunction of Alzheimer's disease.. Iubmb Life
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Anti-Androgen Drugs in the Treatment of Obsessive-Compulsive Disorder: A Systematic Review
Homa Nomani;Amir Hooshang Mohammadpour;Seyed Mohammad Hassan Moallem;Mahdi Jannati YazdanAbad;George E. Barreto;Amirhossein Sahebkar; (2020) Anti-Androgen Drugs in the Treatment of Obsessive-Compulsive Disorder: A Systematic Review. Current medicinal chemistry
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Raloxifene Potentiates The Effect Of Fluoxetine Against Maximal Electroshock Induced Seizures In Mice
ttoo FH, Tabassum N, Javed MN, Nigar S, Sharma S, Barkat MA, Harshita, Alam MS, Ansari MA, Barreto GE, Ashraf GM (2020) Raloxifene Potentiates The Effect Of Fluoxetine Against Maximal Electroshock Induced Seizures In Mice. European Journal Of Pharmaceutical Sciences
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Curcumin: a phytochemical modulator of estrogens and androgens in tumors of the reproductive system
Mohajeri M, Bianconi V, Ávila-Rodriguez MF, Barreto GE, Jamialahmadi T, Pirro M, Sahebkar (2020) Curcumin: a phytochemical modulator of estrogens and androgens in tumors of the reproductive system. Pharmacological Research
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Developmental lead (Pb)-induced deficits in redox and bioenergetic status of cerebellar synapses are ameliorated by ascorbate supplementation
Ahmad F.;Haque S.;Ravinayagam V.;Ahmad A.;Kamli M.R.;Barreto G.E.;Ghulam Md Ashraf (2020) Developmental lead (Pb)-induced deficits in redox and bioenergetic status of cerebellar synapses are ameliorated by ascorbate supplementation. Toxicology
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Bioinformatic Study of Involved Mechanisms in Relapse and Drug Resistance of Tamoxifen-Treated Breast Cancer.
Keikha M;Barreto GE;González J;Sahebkar A; (2020) Bioinformatic Study of Involved Mechanisms in Relapse and Drug Resistance of Tamoxifen-Treated Breast Cancer.. Anti-Cancer Agents In Medicinal Chemistry
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Lipid-based nanoformulations in the treatment of neurological disorders
Pottoo FH, Sharma S, Javed MN, Barkat MA, Harshita, Alam MS, Naim MJ, Alam O, Ansari MA, Barreto GE, Ashraf GM (2020) Lipid-based nanoformulations in the treatment of neurological disorders. Drug Metabolism Reviews
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The effects of statins on microglial cells to protect against neurodegenerative disorders: A mechanistic review
Bagheri H, Ghasemi F, Barreto GE, Sathyapalan T, Jamialahmadi T, Sahebkar A (2019) The effects of statins on microglial cells to protect against neurodegenerative disorders: A mechanistic review. Biofactors
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Higher zinc concentrations in hair of Parkinson's disease are associated with psychotic complications and depression
Dos Santos AB, Bezerra MA, Rocha ME, Barreto GE, Kohlmeier KA (2019) Higher zinc concentrations in hair of Parkinson's disease are associated with psychotic complications and depression. Journal Of Neural Transmission
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Efficacy of curcumin on prevention of drugâinduced nephrotoxicity: A review of animal studies
Javad Motaharinia;Yunes Panahi;George E. Barreto;Fatemeh Beiraghdar;Amirhossein Sahebkar; (2019) Efficacy of curcumin on prevention of drugâinduced nephrotoxicity: A review of animal studies. Biofactors
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Astrocytes Mediate Protective Actions of Estrogenic Compounds after Traumatic Brain Injury
Martin-Jimenez, C.,Gaitan-Vaca, D. M.,Areiza, N.,Echeverria, V.,Ashraf, G. M.,Gonzalez, J.,Sahebkar, A.,Garcia-Segura, L. M.,Barreto, G. E. (2019) Astrocytes Mediate Protective Actions of Estrogenic Compounds after Traumatic Brain Injury. Neuroendocrinology :142-160
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Tibolone attenuates inflammatory response by palmitic acid and preserves mitochondrial membrane potential in astrocytic cells through estrogen receptor beta
Gonzalez-Giraldo, Y.,Forero, D. A.,Echeverria, V.,Garcia-Segura, L. M.,Barreto, G. E. (2019) Tibolone attenuates inflammatory response by palmitic acid and preserves mitochondrial membrane potential in astrocytic cells through estrogen receptor beta. Molecular And Cellular Endocrinology :65-78
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Modulatory effects of curcumin on heat shock proteins in cancer: A promising therapeutic approach
Fatemeh Forouzanfar;George Barreto;Muhammed Majeed;Amirhossein Sahebkar; (2019) Modulatory effects of curcumin on heat shock proteins in cancer: A promising therapeutic approach. Biofactors
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Molecular cloning, expression, purification, and functional characterization of SPâ22 gene from Bombyx mori
Elshareef Salah Eldein;Mohnad Abdalla;Wafa Ali Eltayb;Amr Ahmed ElâArabey;Magdah Ganash;Fawaz D. Alshammari;George Barreto;Ghulam Md Ashraf; (2019) Molecular cloning, expression, purification, and functional characterization of SPâ22 gene from Bombyx mori. Journal Of Cellular Biochemistry
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Antioxidative potential of antidiabetic agents: A possible protective mechanism against vascular complications in diabetic patients
Yaribeygi, H.,Butler, A. E.,Barreto, G. E.,Sahebkar, A. (2019) Antioxidative potential of antidiabetic agents: A possible protective mechanism against vascular complications in diabetic patients. Journal Of Cellular Physiology :2436-2446
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The Therapeutic Potential of Mesenchymal Stem Cell-Derived Exosomes in Treatment of Neurodegenerative Diseases
Gorabi AM, Kiaie N, Barreto GE, Read MI, Tafti HA, Sahebkar A (2019) The Therapeutic Potential of Mesenchymal Stem Cell-Derived Exosomes in Treatment of Neurodegenerative Diseases. Molecular Neurobiology
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Beneficial effects of nâhexane bark extract of Onosma echioides L. on diabetic peripheral neuropathy
Ambreen Shoaib;Badruddeen;Rakesh Kumar Dixit;Magdah Ganash;George Barreto;Ghulam Md Ashraf;Hefazat Hussain Siddiqui; (2019) Beneficial effects of nâhexane bark extract of Onosma echioides L. on diabetic peripheral neuropathy. Journal Of Cellular Biochemistry
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Anti-inflammatory effects of resolvins in diabetic nephropathy: Mechanistic pathways
Yaribeygi, H.,Atkin, S. L.,Simental-Mendia, L. E.,Barreto, G. E.,Sahebkar, A. (2019) Anti-inflammatory effects of resolvins in diabetic nephropathy: Mechanistic pathways. Journal Of Cellular Physiology
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Novel computational deep learning strategy for neuroprotection identification reveals unique set of nicotine analogs as potential therapeutic compounds against Parkinsonâs disease
Felipe Rojas-RodrÃguez;Carlos Morantes;Andrés Pinzón;George E. Barreto;Ricardo Cabezas;Leonardo Mariño;Janneth González; (2019) Novel computational deep learning strategy for neuroprotection identification reveals unique set of nicotine analogs as potential therapeutic compounds against Parkinsonâs disease.
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Molecular mechanisms and cellular events involved in the neuroprotective actions of estradiol. Analysis of sex differences
Azcoitia I, Barreto GE, Garcia-Segura LM (2019) Molecular mechanisms and cellular events involved in the neuroprotective actions of estradiol. Analysis of sex differences. Frontiers In Neuroendocrinology
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Melatonin in Alzheimer's Disease: A Latent Endogenous Regulator of Neurogenesis to Mitigate Alzheimer's Neuropathology
Hossain MF, Uddin MS, Uddin GMS, Sumsuzzman DM, Islam MS, Barreto GE, Mathew B, Ashraf GM (2019) Melatonin in Alzheimer's Disease: A Latent Endogenous Regulator of Neurogenesis to Mitigate Alzheimer's Neuropathology. Molecular Neurobiology
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Impact of sex differences and gender specificity on behavioral characteristics and pathophysiology of neurodegenerative disorders.
Ullah MF, Ahmad A, Bhat SH, Abu-Duhier FM, Barreto GE, Ashraf GM (2019) Impact of sex differences and gender specificity on behavioral characteristics and pathophysiology of neurodegenerative disorders.. Neuroscience And Biobehavioral Reviews :95-105
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Protein modeling, molecular network and molecular dynamics study of newly sequenced interleukin-18 (IL-18) gene in Mus musculus
Yadav, B. S.,Chaturvedi, N.,Yadav, P. K.,Marina, N.,Ganash, M.,Barreto, G. E.,Ashraf, G. M.,Ahmad, K.,Baig, M. H. (2019) Protein modeling, molecular network and molecular dynamics study of newly sequenced interleukin-18 (IL-18) gene in Mus musculus. Journal Of Cellular Physiology
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Molecular mechanisms involved in the protective actions of Selective Estrogen Receptor Modulators in brain cells
Baez-Jurado, E.,Rincon-Benavides, M. A.,Hidalgo-Lanussa, O.,Guio-Vega, G.,Ashraf, G. M.,Sahebkar, A.,Echeverria, V.,Garcia-Segura, L. M.,Barreto, G. E. (2019) Molecular mechanisms involved in the protective actions of Selective Estrogen Receptor Modulators in brain cells. Frontiers In Neuroendocrinology :44-64
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The Synergistic Effect of Raloxifene, Fluoxetine, and Bromocriptine Protects Against Pilocarpine-Induced Status Epilepticus and Temporal Lobe Epilepsy
Pottoo, F. H.,Tabassum, N.,Javed, M. N.,Nigar, S.,Rasheed, R.,Khan, A.,Barkat, M. A.,Alam, M. S.,Maqbool, A.,Ansari, M. A.,Barreto, G. E.,Ashraf, G. M. (2019) The Synergistic Effect of Raloxifene, Fluoxetine, and Bromocriptine Protects Against Pilocarpine-Induced Status Epilepticus and Temporal Lobe Epilepsy. Molecular Neurobiology :1233-1247
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Endothelial PPARγ Is Crucial for Averting Age-Related Vascular Dysfunction by Stalling Oxidative Stress and ROCK.
Uddin MS, Kabir MT, Jakaria M, Mamun AA, Niaz K, Amran MS, Barreto GE, Ashraf GM. (2019) Endothelial PPARγ Is Crucial for Averting Age-Related Vascular Dysfunction by Stalling Oxidative Stress and ROCK.. Neurotoxicity Research
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Autophagic dysfunction in Alzheimer's disease: Cellular and molecular mechanistic approaches to halt Alzheimer's pathogenesis
Uddin, M. S.,Mamun, A. A.,Labu, Z. K.,Hidalgo-Lanussa, O.,Barreto, G. E.,Ashraf, G. M. (2019) Autophagic dysfunction in Alzheimer's disease: Cellular and molecular mechanistic approaches to halt Alzheimer's pathogenesis. Journal Of Cellular Physiology :8094-8112
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Raloxifene attenuates oxidative stress and preserves mitochondrial function in astrocytic cells upon glucose deprivation
Vesga-Jimenez, D. J.,Hidalgo-Lanussa, O.,Baez-Jurado, E.,Echeverria, V.,Ashraf, G. M.,Sahebkar, A.,Barreto, G. E. (2019) Raloxifene attenuates oxidative stress and preserves mitochondrial function in astrocytic cells upon glucose deprivation. J Cell Physiolj Cell Physiol :2051-2057
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(E)-Nicotinaldehyde O-Cinnamyloxime, a Nicotine Analog, Attenuates Neuronal Cells Death Against Rotenone-Induced Neurotoxicity
Jurado-Coronel, J. C.,Loaiza, A. E.,Diaz, J. E.,Cabezas, R.,Ashraf, G. M.,Sahebkar, A.,Echeverria, V.,Gonzalez, J.,Barreto, G. E. (2019) (E)-Nicotinaldehyde O-Cinnamyloxime, a Nicotine Analog, Attenuates Neuronal Cells Death Against Rotenone-Induced Neurotoxicity. Molecular Neurobiology :1221-1232
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Lipotoxicity, neuroinflammation, glial cells and estrogenic compounds
Hidalgo-Lanussa O, Baez-Jurado E, Echeverria V, Ashraf GM, Sahebkar A, Garcia-Segura LM, Melcangi RC, Barreto GE (2019) Lipotoxicity, neuroinflammation, glial cells and estrogenic compounds. Journal Of Neuroendocrinology
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Prevalence, pathological mechanisms, and genetic basis of limb-girdle muscular dystrophies: A review
Taghizadeh, E.,Rezaee, M.,Barreto, G. E.,Sahebkar, A. (2019) Prevalence, pathological mechanisms, and genetic basis of limb-girdle muscular dystrophies: A review. Journal Of Cellular Physiology :7874-7884
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TERT inhibition leads to reduction of IL6 expression induced by palmitic acid and interferes with the protective effects of tibolone in an astrocytic cell model.
Gonzalez-Giraldo Y, Garzón-Benitez AV, Forero DA, Barreto GE (2019) TERT inhibition leads to reduction of IL6 expression induced by palmitic acid and interferes with the protective effects of tibolone in an astrocytic cell model.. Journal Of Neuroendocrinology
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Chitosan-based delivery systems for curcumin: A review of pharmacodynamic and pharmacokinetic aspects
Saheb, M.,Fereydouni, N.,Nemati, S.,Barreto, G. E.,Johnston, T. P.,Sahebkar, A. (2019) Chitosan-based delivery systems for curcumin: A review of pharmacodynamic and pharmacokinetic aspects. Journal Of Cellular Physiology
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NeuroMuscleDB: a Database of Genes Associated with Muscle Development, Neuromuscular Diseases, Ageing, and Neurodegeneration
Baig, M. H.,Rashid, I.,Srivastava, P.,Ahmad, K.,Jan, A. T.,Rabbani, G.,Choi, D.,Barreto, G. E.,Ashraf, G. M.,Lee, E. J.,Choi, I. (2019) NeuroMuscleDB: a Database of Genes Associated with Muscle Development, Neuromuscular Diseases, Ageing, and Neurodegeneration. Molecular Neurobiology
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Cholinesterase Inhibitors for Alzheimer Disease: Multitargeting Strategy based on Anti-Alzheimer's Drugs Repositioning
Kabir MT, Uddin MS, Begum MM, Thangapandiyan S, Rahman MS, Aleya L, Mathew B, Ahmed M, Ashraf GM, Barreto GE (2019) Cholinesterase Inhibitors for Alzheimer Disease: Multitargeting Strategy based on Anti-Alzheimer's Drugs Repositioning. Current Pharmaceutical Design
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Anti-androgen Drugs in the Treatment of Obsessive-Compulsive Disorder: A Systematic Review
Nomani H, Mohammadpour AH, Moallem SMH, YazdanAbad MJ, Barreto GE, Sahebkar A (2019) Anti-androgen Drugs in the Treatment of Obsessive-Compulsive Disorder: A Systematic Review. Current Medicinal Chemistry
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Carbon nanomaterials and amyloid beta interactions: Possible potentials in the detection and treatment of Alzheimer's disease
Mohajeri, M.,Behnam, B.,Barreto, G. E.,Sahebkar, A. (2019) Carbon nanomaterials and amyloid beta interactions: Possible potentials in the detection and treatment of Alzheimer's disease. Pharmacological Research
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Secretome of Mesenchymal Stem Cells and Its Potential Protective Effects on Brain Pathologies
Baez-Jurado, E.,Hidalgo-Lanussa, O.,Barrera-Bailon, B.,Sahebkar, A.,Ashraf, G. M.,Echeverria, V.,Barreto, G. E. (2019) Secretome of Mesenchymal Stem Cells and Its Potential Protective Effects on Brain Pathologies. Molecular Neurobiology
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APOE and Alzheimer's Disease: Evidence Mounts that Targeting APOE4 may Combat Alzheimer's Pathogenesis
Uddin, M. S.,Kabir, M. T.,Al Mamun, A.,Abdel-Daim, M. M.,Barreto, G. E.,Ashraf, G. M. (2018) APOE and Alzheimer's Disease: Evidence Mounts that Targeting APOE4 may Combat Alzheimer's Pathogenesis. Molecular Neurobiology
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Gold nanoparticles: A plausible tool to combat neurological bacterial infections in humans
Rizvi, S. M. D.,Hussain, T.,Ahmed, A. B. F.,Alshammari, T. M.,Moin, A.,Ahmed, M. Q.,Barreto, G. E.,Kamal, M. A.,Ashraf, G. M. (2018) Gold nanoparticles: A plausible tool to combat neurological bacterial infections in humans. Biomed Pharmacotherbiomed Pharmacother :7-18
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Growth Factors and Neuroglobin in Astrocyte Protection Against Neurodegeneration and Oxidative Stress
Cabezas, R.,Baez-Jurado, E.,Hidalgo-Lanussa, O.,Echeverria, V.,Ashrad, G. M.,Sahebkar, A.,Barreto, G. E. (2018) Growth Factors and Neuroglobin in Astrocyte Protection Against Neurodegeneration and Oxidative Stress. Mol Neurobiolmol Neurobiol
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Pharmacoinformatics and molecular docking reveal potential drug candidates against Schizophrenia to target TAAR6
Tahir, R. A.,Wu, H.,Javed, N.,Khalique, A.,Khan, S. A. F.,Mir, A.,Ahmed, M. S.,Barreto, G. E.,Qing, H.,Ashraf, G. M.,Sehgal, S. A. (2018) Pharmacoinformatics and molecular docking reveal potential drug candidates against Schizophrenia to target TAAR6. Journal Of Cellular Physiology
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Macrophage plasticity, polarization and function in response to curcumin, a diet-derived polyphenol, as an immunomodulatory agent
Mohammadi, A.,Blesso, C. N.,Barreto, G. E.,Banach, M.,Majeed, M.,Sahebkar, A. (2018) Macrophage plasticity, polarization and function in response to curcumin, a diet-derived polyphenol, as an immunomodulatory agent. J Nutr Biochemj Nutr Biochem :1-16
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Nootropic and Anti-Alzheimer's Actions of Medicinal Plants: Molecular Insight into Therapeutic Potential to Alleviate Alzheimer's Neuropathology
Uddin, M. S.,Al Mamun, A.,Kabir, M. T.,Jakaria, M.,Mathew, B.,Barreto, G. E.,Ashraf, G. M. (2018) Nootropic and Anti-Alzheimer's Actions of Medicinal Plants: Molecular Insight into Therapeutic Potential to Alleviate Alzheimer's Neuropathology. Molecular Neurobiology
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Ionic gradient liposomes: Recent advances in the stable entrapment and prolonged released of local anesthetics and anticancer drugs
Fatima, M. T.,Islam, Z.,Ahmad, E.,Barreto, G. E.,Md Ashraf, G. (2018) Ionic gradient liposomes: Recent advances in the stable entrapment and prolonged released of local anesthetics and anticancer drugs. Biomed Pharmacotherbiomed Pharmacother :34-43
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Blockade of Neuroglobin Reduces Protection of Conditioned Medium from Human Mesenchymal Stem Cells in Human Astrocyte Model (T98G) Under a Scratch Assay
Baez-Jurado, E.,Vega, G. G.,Aliev, G.,Tarasov, V. V.,Esquinas, P.,Echeverria, V.,Barreto, G. E. (2018) Blockade of Neuroglobin Reduces Protection of Conditioned Medium from Human Mesenchymal Stem Cells in Human Astrocyte Model (T98G) Under a Scratch Assay. Mol Neurobiolmol Neurobiol :2285-2300
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The effect of fasting or calorie restriction on autophagy induction: A review of the literature
Bagherniya, M.,Butler, A. E.,Barreto, G. E.,Sahebkar, A. (2018) The effect of fasting or calorie restriction on autophagy induction: A review of the literature. Ageing Res Revageing Res Rev :183-197
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Impact of fibrates on circulating cystatin C levels: a systematic review and meta-analysis of clinical trials
Sahebkar, A.,Simental-Mendia, L. E.,Pirro, M.,Montecucco, F.,Carbone, F.,Banach, M.,Barreto, G. E.,Butler, A. E. (2018) Impact of fibrates on circulating cystatin C levels: a systematic review and meta-analysis of clinical trials. Ann Medann Med :485-493
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Cotinine Plus Krill Oil Decreased Depressive Behavior, and Increased Astrocytes Survival in the Hippocampus of Mice Subjected to Restraint Stress
Mendoza, C.,Perez-Urrutia, N.,Alvarez-Ricartes, N.,Barreto, G. E.,Perez-Ordas, R.,Iarkov, A.,Echeverria, V. (2018) Cotinine Plus Krill Oil Decreased Depressive Behavior, and Increased Astrocytes Survival in the Hippocampus of Mice Subjected to Restraint Stress. Front Neuroscifront Neurosci :952-
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Intranasal Cotinine Plus Krill Oil Facilitates Fear Extinction, Decreases Depressive-Like Behavior, and Increases Hippocampal Calcineurin A Levels in Mice
Alvarez-Ricartes, N.,Oliveros-Matus, P.,Mendoza, C.,Perez-Urrutia, N.,Echeverria, F.,Iarkov, A.,Barreto, G. E.,Echeverria, V. (2018) Intranasal Cotinine Plus Krill Oil Facilitates Fear Extinction, Decreases Depressive-Like Behavior, and Increases Hippocampal Calcineurin A Levels in Mice. Molecular Neurobiology :7949-7960
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Peptide based therapeutics and their use for the treatment of neurodegenerative and other diseases
Baig, M. H.,Ahmad, K.,Saeed, M.,Alharbi, A. M.,Barreto, G. E.,Ashraf, G. M.,Choi, I. (2018) Peptide based therapeutics and their use for the treatment of neurodegenerative and other diseases. Biomed Pharmacotherbiomed Pharmacother :574-581
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Conditioned Medium of Human Adipose Mesenchymal Stem Cells Increases Wound Closure and Protects Human Astrocytes Following Scratch Assay In Vitro
Baez-Jurado, E.,Hidalgo-Lanussa, O.,Guio-Vega, G.,Ashraf, G. M.,Echeverria, V.,Aliev, G.,Barreto, G. E. (2018) Conditioned Medium of Human Adipose Mesenchymal Stem Cells Increases Wound Closure and Protects Human Astrocytes Following Scratch Assay In Vitro. Mol Neurobiolmol Neurobiol :5377-5392
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Urotensin II: Molecular Mechanisms of Biological Activity
Svistunov, A. A.,Tarasov, V. V.,Shakhmardanova, S. A.,Sologova, S. S.,Bagaturiya, E. T.,Chubarev, V. N.,Galenko-Yaroshevsky, P. A.,Avila-Rodriguez, M. F.,Barreto, G. E.,Aliev, G. (2018) Urotensin II: Molecular Mechanisms of Biological Activity. Curr Protein Pept Scicurr Protein Pept Sci :924-934
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Sleep Disorders Associated With Alzheimer's Disease: A Perspective
Brzecka, A.,Leszek, J.,Ashraf, G. M.,Ejma, M.,Avila-Rodriguez, M. F.,Yarla, N. S.,Tarasov, V. V.,Chubarev, V. N.,Samsonova, A. N.,Barreto, G. E.,Aliev, G. (2018) Sleep Disorders Associated With Alzheimer's Disease: A Perspective. Front Neuroscifront Neurosci :330-
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Correction to: Cotinine: A Therapy for Memory Extinction in Post-traumatic Stress Disorder
Mendoza, C.,Barreto, G. E.,Iarkov, A.,Tarasov, V. V.,Aliev, G.,Echeverria, V. (2018) Correction to: Cotinine: A Therapy for Memory Extinction in Post-traumatic Stress Disorder. Mol Neurobiolmol Neurobiol :6712-
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Trans-aconitic acid inhibits the growth and photosynthesis of Glycine max
Bortolo, Tdsc,Marchiosi, R.,Vigano, J.,Siqueira-Soares, R. C.,Ferro, A. P.,Barreto, G. E.,Bido, G. S.,Abrahao, J.,Dos Santos, W. D.,Ferrarese-Filho, O. (2018) Trans-aconitic acid inhibits the growth and photosynthesis of Glycine max. Plant Physiol Biochemplant Physiol Biochem :490-496
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Mitochondrial Neuroglobin Is Necessary for Protection Induced by Conditioned Medium from Human Adipose-Derived Mesenchymal Stem Cells in Astrocytic Cells Subjected to Scratch and Metabolic Injury
Baez-Jurado, E.,Guio-Vega, G.,Hidalgo-Lanussa, O.,Gonzalez, J.,Echeverria, V.,Ashraf, G. M.,Sahebkar, A.,Barreto, G. E. (2018) Mitochondrial Neuroglobin Is Necessary for Protection Induced by Conditioned Medium from Human Adipose-Derived Mesenchymal Stem Cells in Astrocytic Cells Subjected to Scratch and Metabolic Injury. Mol Neurobiolmol Neurobiol
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Cellular and Molecular Aspects of Parkinson Treatment: Future Therapeutic Perspectives
Jamebozorgi, K.,Taghizadeh, E.,Rostami, D.,Pormasoumi, H.,Barreto, G. E.,Hayat, S. M. G.,Sahebkar, A. (2018) Cellular and Molecular Aspects of Parkinson Treatment: Future Therapeutic Perspectives. Mol Neurobiolmol Neurobiol
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Author Correction: Pyridoxine dipharmacophore derivatives as potent glucokinase activators for the treatment of type 2 diabetes mellitus
Dzyurkevich, M. S.,Babkov, D. A.,Shtyrlin, N. V.,Mayka, O. Y.,Iksanova, A. G.,Vassiliev, P. M.,Balakin, K. V.,Spasov, A. A.,Tarasov, V. V.,Barreto, G.,Shtyrlin, Y. G.,Aliev, G. (2018) Author Correction: Pyridoxine dipharmacophore derivatives as potent glucokinase activators for the treatment of type 2 diabetes mellitus. Sci Repsci Rep :6489-
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New ABCC2 rs3740066 and rs2273697 Polymorphisms Identified in a Healthy Colombian Cohort
Bustos-Cruz, R. H.,Martinez, L. R.,Garcia, J. C.,Barreto, G. E.,Suarez, F. (2018) New ABCC2 rs3740066 and rs2273697 Polymorphisms Identified in a Healthy Colombian Cohort. Pharmaceuticspharmaceutics
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The cytochrome P450 isoenzyme and some new opportunities for the prediction of negative drug interaction in vivo
Sychev, D. A.,Ashraf, G. M.,Svistunov, A. A.,Maksimov, M. L.,Tarasov, V. V.,Chubarev, V. N.,Otdelenov, V. A.,Denisenko, N. P.,Barreto, G. E.,Aliev, G. (2018) The cytochrome P450 isoenzyme and some new opportunities for the prediction of negative drug interaction in vivo. Drug Design Development And Therapy :1147-1156
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Inhibiting Effect of Zinc Oxide Nanoparticles on Advanced Glycation Products and Oxidative Modifications: a Potential Tool to Counteract Oxidative Stress in Neurodegenerative Diseases
Ashraf, J. M.,Ansari, M. A.,Fatma, S.,Abdullah, S. M. S.,Iqbal, J.,Madkhali, A.,Hamali, A. H.,Ahmad, S.,Jerah, A.,Echeverria, V.,Barreto, G. E.,Ashraf, G. M. (2018) Inhibiting Effect of Zinc Oxide Nanoparticles on Advanced Glycation Products and Oxidative Modifications: a Potential Tool to Counteract Oxidative Stress in Neurodegenerative Diseases. Mol Neurobiolmol Neurobiol :7438-7452
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Extracts of Physalis peruviana Protect Astrocytic Cells Under Oxidative Stress With Rotenone
Areiza-Mazo, N.,Robles, J.,Zamudio-Rodriguez, J. A.,Giraldez, L.,Echeverria, V.,Barrera-Bailon, B.,Aliev, G.,Sahebkar, A.,Ashraf, G. M.,Barreto, G. E. (2018) Extracts of Physalis peruviana Protect Astrocytic Cells Under Oxidative Stress With Rotenone. Front Chemfront Chem :276-
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Tibolone Reduces Oxidative Damage and Inflammation in Microglia Stimulated with Palmitic Acid through Mechanisms Involving Estrogen Receptor Beta
Hidalgo-Lanussa, O.,Avila-Rodriguez, M.,Baez-Jurado, E.,Zamudio, J.,Echeverria, V.,Garcia-Segura, L. M.,Barreto, G. E. (2018) Tibolone Reduces Oxidative Damage and Inflammation in Microglia Stimulated with Palmitic Acid through Mechanisms Involving Estrogen Receptor Beta. Mol Neurobiolmol Neurobiol :5462-5477
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Lignin-induced growth inhibition in soybean exposed to iron oxide nanoparticles
Cunha Lopes, T. L.,de Cassia Siqueira-Soares, R.,Goncalves de Almeida, G. H.,Romano de Melo, G. S.,Barreto, G. E.,de Oliveira, D. M.,Dos Santos, W. D.,Ferrarese-Filho, O.,Marchiosi, R. (2018) Lignin-induced growth inhibition in soybean exposed to iron oxide nanoparticles. Chemospherechemosphere :226-234
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Correction to: Intranasal Cotinine Plus Krill Oil Facilitates Fear Extinction, Decreases Depressive-Like Behavior, and Increases Hippocampal Calcineurin A Levels in Mice
Alvarez-Ricartes, N.,Oliveros-Matus, P.,Mendoza, C.,Perez-Urrutia, N.,Echeverria, F.,Iarkov, A.,Barreto, G. E.,Echeverria, V. (2018) Correction to: Intranasal Cotinine Plus Krill Oil Facilitates Fear Extinction, Decreases Depressive-Like Behavior, and Increases Hippocampal Calcineurin A Levels in Mice. Mol Neurobiolmol Neurobiol :7961-
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Tibolone Preserves Mitochondrial Functionality and Cell Morphology in Astrocytic Cells Treated with Palmitic Acid
Gonzalez-Giraldo, Y.,Garcia-Segura, L. M.,Echeverria, V.,Barreto, G. E. (2018) Tibolone Preserves Mitochondrial Functionality and Cell Morphology in Astrocytic Cells Treated with Palmitic Acid. Mol Neurobiolmol Neurobiol :4453-4462
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Hair in Parkinson's disease patients exhibits differences in Calcium, Iron and Zinc concentrations measured by flame atomic absorption spectrometry - FAAS
Dos Santos, A. B.,Kohlmeier, K. A.,Rocha, M. E.,Barreto, G. E.,Barreto, J. A.,de Souza, A. C. A.,Bezerra, M. A. (2018) Hair in Parkinson's disease patients exhibits differences in Calcium, Iron and Zinc concentrations measured by flame atomic absorption spectrometry - FAAS. J Trace Elem Med Biolj Trace Elem Med Biol :134-139
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Role of GTPases in the Regulation of Mitochondrial Dynamics in Alzheimer's Disease and CNS-Related Disorders
Alexiou, A.,Soursou, G.,Chatzichronis, S.,Gasparatos, E.,Kamal, M. A.,Yarla, N. S.,Perveen, A.,Barreto, G. E.,Ashraf, G. M. (2018) Role of GTPases in the Regulation of Mitochondrial Dynamics in Alzheimer's Disease and CNS-Related Disorders. Mol Neurobiolmol Neurobiol
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An optimized alternative for phenolic compound-extraction of strawberry bagasse agro-industrial residues
Felix, A.C.S.;Novaes, C.G.;Rocha, M.P.;Barreto, G.E.;Franco, M.;do Nascimento Junior, B.B.;Alvarez, L.D.G.; (2018) An optimized alternative for phenolic compound-extraction of strawberry bagasse agro-industrial residues. Journal Of Microbiology, Biotechnology And Food Sciences
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Curcumin as a therapeutic candidate for multiple sclerosis: Molecular mechanisms and targets
Ghanaatian, N.,Lashgari, N. A.,Abdolghaffari, A. H.,Rajaee, S. M.,Panahi, Y.,Barreto, G. E.,Butler, A. E.,Sahebkar, A. (2018) Curcumin as a therapeutic candidate for multiple sclerosis: Molecular mechanisms and targets. J Cell Physiolj Cell Physiol
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The Synthetic Steroid Tibolone Decreases Reactive Gliosis and Neuronal Death in the Cerebral Cortex of Female Mice After a Stab Wound Injury
Crespo-Castrillo, A.,Yanguas-Casas, N.,Arevalo, M. A.,Azcoitia, I.,Barreto, G. E.,Garcia-Segura, L. M. (2018) The Synthetic Steroid Tibolone Decreases Reactive Gliosis and Neuronal Death in the Cerebral Cortex of Female Mice After a Stab Wound Injury. Mol Neurobiolmol Neurobiol :8651-8667
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Cell therapy for spinal cord injury with olfactory ensheathing glia cells (OECs)
Gomez, R. M.,Sanchez, M. Y.,Portela-Lomba, M.,Ghotme, K.,Barreto, G. E.,Sierra, J.,Moreno-Flores, M. T. (2018) Cell therapy for spinal cord injury with olfactory ensheathing glia cells (OECs). Gliaglia :1267-1301
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Combined Strategy for a Reliable Evaluation of Spinal Cord Injury Using an in vivo Model
Gomez, R. M.,Ghotme, K.,Nino, J. J.,Quiroz-Padilla, M.,Vargas, D.,Dominguez, A. R.,Barreto, G. E.,Sanchez, M. Y. (2018) Combined Strategy for a Reliable Evaluation of Spinal Cord Injury Using an in vivo Model. Cent Nerv Syst Agents Med Chemcent Nerv Syst Agents Med Chem :49-57
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Mild cognitive impairment due to Alzheimer disease: Contemporary approaches to diagnostics and pharmacological intervention
Bachurin, S. O.,Gavrilova, S. I.,Samsonova, A.,Barreto, G. E.,Aliev, G. (2018) Mild cognitive impairment due to Alzheimer disease: Contemporary approaches to diagnostics and pharmacological intervention. Pharmacol Respharmacol Res :216-226
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PDGF-BB Preserves Mitochondrial Morphology, Attenuates ROS Production, and Upregulates Neuroglobin in an Astrocytic Model Under Rotenone Insult
Cabezas, R.,Vega-Vela, N. E.,Gonzalez-Sanmiguel, J.,Gonzalez, J.,Esquinas, P.,Echeverria, V.,Barreto, G. E. (2018) PDGF-BB Preserves Mitochondrial Morphology, Attenuates ROS Production, and Upregulates Neuroglobin in an Astrocytic Model Under Rotenone Insult. Mol Neurobiolmol Neurobiol :3085-3095
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Sex differences in Parkinson's disease: Features on clinical symptoms, treatment outcome, sexual hormones and genetics
Jurado-Coronel, J. C.,Cabezas, R.,Avila Rodriguez, M. F.,Echeverria, V.,Garcia-Segura, L. M.,Barreto, G. E. (2018) Sex differences in Parkinson's disease: Features on clinical symptoms, treatment outcome, sexual hormones and genetics. Front Neuroendocrinolfront Neuroendocrinol :18-30
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Corrigendum to "Mild cognitive impairment due to Alzheimer disease: Contemporary approaches to diagnostics and pharmacological intervention" [Pharmacol. Res. 129 (2018) 216-226]
Bachurin, S. O.,Gavrilova, S. I.,Samsonova, A.,Barreto, G. E.,Aliev, G. (2018) Corrigendum to "Mild cognitive impairment due to Alzheimer disease: Contemporary approaches to diagnostics and pharmacological intervention" [Pharmacol. Res. 129 (2018) 216-226]. Pharmacol Respharmacol Res :245-
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Correction to: Growth Factors and Neuroglobin in Astrocyte Protection Against Neurodegeneration and Oxidative Stress
Cabezas, R.,Baez-Jurado, E.,Hidalgo-Lanussa, O.,Echeverria, V.,Ashraf, G. M.,Sahebkar, A.,Barreto, G. E. (2018) Correction to: Growth Factors and Neuroglobin in Astrocyte Protection Against Neurodegeneration and Oxidative Stress. Mol Neurobiolmol Neurobiol
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Chemosensitizing Activity of Histone Deacetylases Inhibitory Cyclic Hydroxamic Acids for Combination Chemotherapy of Lymphatic Leukemia
Mishchenko, D. V.,Neganova, M. E.,Klimanova, E. N.,Sashenkova, T. E.,Klochkov, S. G.,Shevtsova, E. F.,Vystorop, I. V.,Tarasov, V. V.,Chubarev, V. N.,Samsonova, A. N.,Ashraf, G. M.,Barreto, G.,Yarla, N. S.,Aliev, G. (2018) Chemosensitizing Activity of Histone Deacetylases Inhibitory Cyclic Hydroxamic Acids for Combination Chemotherapy of Lymphatic Leukemia. Curr Cancer Drug Targetscurr Cancer Drug Targets :365-371
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Gliomas: New Perspectives in Diagnosis, Treatment and Prognosis
Ghotme, K. A.,Barreto, G. E.,Echeverria, V.,Gonzalez, J.,Bustos, R. H.,Sanchez, M.,Leszek, J.,Yarla, N. S.,Gomez, R. M.,Tarasov, V. V.,Ashraf, G. M.,Aliev, G. (2017) Gliomas: New Perspectives in Diagnosis, Treatment and Prognosis. Curr Top Med Chemcurr Top Med Chem :1438-1447
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Securinine Derivatives as Potential Anti-amyloid Therapeutic Approach
Neganova, M. E.,Klochkov, S. G.,Petrova, L. N.,Shevtsova, E. F.,Afanasieva, S. V.,Chudinova, E. S.,Fisenko, V. P.,Bachurin, S. O.,Barreto, G. E.,Aliev, G. (2017) Securinine Derivatives as Potential Anti-amyloid Therapeutic Approach. Cns Neurol Disord Drug Targetscns Neurol Disord Drug Targets :351-355
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Astrocytes and endoplasmic reticulum stress: A bridge between obesity and neurodegenerative diseases
Martin-Jimenez, C. A.,Garcia-Vega, A.,Cabezas, R.,Aliev, G.,Echeverria, V.,Gonzalez, J.,Barreto, G. E. (2017) Astrocytes and endoplasmic reticulum stress: A bridge between obesity and neurodegenerative diseases. Prog Neurobiolprog Neurobiol :45-68
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Portacaval shunting causes differential mitochondrial superoxide production in brain regions
Kosenko, E. A.,Tikhonova, L. A.,Alilova, G. A.,Montoliu, C.,Barreto, G. E.,Aliev, G.,Kaminsky, Y. G. (2017) Portacaval shunting causes differential mitochondrial superoxide production in brain regions. Free Radic Biol Medfree Radic Biol Med :109-118
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Cotinine improves visual recognition memory and decreases cortical Tau phosphorylation in the Tg6799 mice
Grizzell, J. A.,Patel, S.,Barreto, G. E.,Echeverria, V. (2017) Cotinine improves visual recognition memory and decreases cortical Tau phosphorylation in the Tg6799 mice. Prog Neuropsychopharmacol Biol Psychiatryprog Neuropsychopharmacol Biol Psychiatry :75-81
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4'-Chlorodiazepam Protects Mitochondria in T98G Astrocyte Cell Line from Glucose Deprivation
Baez, E.,Guio-Vega, G. P.,Echeverria, V.,Sandoval-Rueda, D. A.,Barreto, G. E. (2017) 4'-Chlorodiazepam Protects Mitochondria in T98G Astrocyte Cell Line from Glucose Deprivation. Neurotox Resneurotox Res :163-171
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Approaches of the Transcriptomic Analysis in Astrocytes: Potential Pharmacological Targets
Barreto, G. E.,Gomez, R. M.,Bustos, R. H.,Forero, D. A.,Aliev, G.,Tarasov, V. V.,Yarla, N. S.,Echeverria, V.,Gonzalez, J. (2017) Approaches of the Transcriptomic Analysis in Astrocytes: Potential Pharmacological Targets. Curr Pharm Descurr Pharm Des :4189-4197
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Metabolic Abnormalities of Erythrocytes as a Risk Factor for Alzheimer's Disease
Kosenko, E. A.,Tikhonova, L. A.,Montoliu, C.,Barreto, G. E.,Aliev, G.,Kaminsky, Y. G. (2017) Metabolic Abnormalities of Erythrocytes as a Risk Factor for Alzheimer's Disease. Front Neuroscifront Neurosci :728-
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Intranasal cotinine improves memory, and reduces depressive-like behavior, and GFAP+ cells loss induced by restraint stress in mice
Perez-Urrutia, N.,Mendoza, C.,Alvarez-Ricartes, N.,Oliveros-Matus, P.,Echeverria, F.,Grizzell, J. A.,Barreto, G. E.,Iarkov, A.,Echeverria, V. (2017) Intranasal cotinine improves memory, and reduces depressive-like behavior, and GFAP+ cells loss induced by restraint stress in mice. Exp Neurolexp Neurol :211-221
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Implication of Gastric Cancer Molecular Genetic Markers in Surgical Practice
Nemtsova, M. V.,Strelnikov, V. V.,Tanas, A. S.,Bykov,, II,Zaletaev, D. V.,Rudenko, V. V.,Glukhov, A. I.,Kchorobrich, T. V.,Li, Y.,Tarasov, V. V.,Barreto, G. E.,Aliev, G. (2017) Implication of Gastric Cancer Molecular Genetic Markers in Surgical Practice. Curr Genomicscurr Genomics :408-415
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Synthesis of Saccharumoside-B analogue with potential of antiproliferative and pro-apoptotic activities
Rayavarapu, S.,Yarla, N. S.,Kadiri, S. K.,Bishayee, A.,Vidavalur, S.,Tadikonda, R.,Basha, M.,Pidugu, V. R.,Dowluru, Ksvgk,Lakappa, D. B.,Kamal, M. A.,Md Ashraf, G.,Tarasov, V. V.,Chubarev, V. N.,Klochkov, S. G.,Barreto, G. E.,Bachurin, S. O.,Aliev, G. (2017) Synthesis of Saccharumoside-B analogue with potential of antiproliferative and pro-apoptotic activities. Sci Repsci Rep :8309-
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A Systematic In-silico Analysis of Helicobacter pylori Pathogenic Islands for Identification of Novel Drug Target Candidates
Nammi, D.,Yarla, N. S.,Chubarev, V. N.,Tarasov, V. V.,Barreto, G. E.,Pasupulati, A. M. C.,Aliev, G.,Neelapu, N. R. R. (2017) A Systematic In-silico Analysis of Helicobacter pylori Pathogenic Islands for Identification of Novel Drug Target Candidates. Curr Genomicscurr Genomics :450-465
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Mixture Design and Doehlert Matrix for the Optimization of the Extraction of Phenolic Compounds from Spondias mombin L Apple Bagasse Agroindustrial Residues
Santos Felix, A. C.,Novaes, C. G.,Pires Rocha, M.,Barreto, G. E.,do Nascimento, B. B., Jr.,Giraldez Alvarez, L. D. (2017) Mixture Design and Doehlert Matrix for the Optimization of the Extraction of Phenolic Compounds from Spondias mombin L Apple Bagasse Agroindustrial Residues. Front Chemfront Chem :116-
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Pyridoxine dipharmacophore derivatives as potent glucokinase activators for the treatment of type 2 diabetes mellitus
Dzyurkevich, M. S.,Babkov, D. A.,Shtyrlin, N. V.,Mayka, O. Y.,Iksanova, A. G.,Vassiliev, P. M.,Balakin, K. V.,Spasov, A. A.,Tarasov, V. V.,Barreto, G.,Shtyrlin, Y. G.,Aliev, G. (2017) Pyridoxine dipharmacophore derivatives as potent glucokinase activators for the treatment of type 2 diabetes mellitus. Sci Repsci Rep :16072-
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Ginkgo biloba as an Alternative Medicine in the Treatment of Anxiety in Dementia and other Psychiatric Disorders
Singh, S. K.,Barreto, G. E.,Aliev, G.,Echeverria, V. (2017) Ginkgo biloba as an Alternative Medicine in the Treatment of Anxiety in Dementia and other Psychiatric Disorders. Curr Drug Metabcurr Drug Metab :112-119
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Novel conjugates of aminoadamantanes with carbazole derivatives as potential multitarget agents for AD treatment
Bachurin, S. O.,Shevtsova, E. F.,Makhaeva, G. F.,Grigoriev, V. V.,Boltneva, N. P.,Kovaleva, N. V.,Lushchekina, S. V.,Shevtsov, P. N.,Neganova, M. E.,Redkozubova, O. M.,Bovina, E. V.,Gabrelyan, A. V.,Fisenko, V. P.,Sokolov, V. B.,Aksinenko, A. Y.,Echeverria, V.,Barreto, G. E.,Aliev, G. (2017) Novel conjugates of aminoadamantanes with carbazole derivatives as potential multitarget agents for AD treatment. Sci Repsci Rep :45627-
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Advances in Medicinal Plants with Effects on Anxiety Behavior Associated to Mental and Health Conditions
Barreto, G. E.,Avila-Rodriguez, M.,Foitzick, M.,Aliev, G.,Echeverria, V. (2017) Advances in Medicinal Plants with Effects on Anxiety Behavior Associated to Mental and Health Conditions. Curr Med Chemcurr Med Chem :411-423
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Anthocyanins: Multi-Target Agents for Prevention and Therapy of Chronic Diseases
Putta, S.,Yarla, N. S.,Peluso, I.,Tiwari, D. K.,Reddy, G. V.,Giri, P. V.,Kumar, N.,Malla, R.,Rachel, V.,Bramhachari, P. V.,Reddy, D. Rs,Bade, R.,Mannarapu, M.,Barreto, G. E.,Lu, D. Y.,Tarasov, V. V.,Chubarev, V. N.,Ribeiro, F. F.,Scotti, L.,Scotti, M. T.,Kamal, M. A.,Ashraf, G. M.,Aliev, G.,Perry, G.,Sarker, S. D.,Rao, C. V.,Bishayee, A. (2017) Anthocyanins: Multi-Target Agents for Prevention and Therapy of Chronic Diseases. Curr Pharm Descurr Pharm Des :6321-6346
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Relationship Between Obesity, Alzheimer's Disease, and Parkinson's Disease: an Astrocentric View
Martin-Jimenez, C. A.,Gaitan-Vaca, D. M.,Echeverria, V.,Gonzalez, J.,Barreto, G. E. (2017) Relationship Between Obesity, Alzheimer's Disease, and Parkinson's Disease: an Astrocentric View. Mol Neurobiolmol Neurobiol :7096-7115
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Nanotechnology for Alzheimer Disease
Leszek, J.,Md Ashraf, G.,Tse, W. H.,Zhang, J.,Gasiorowski, K.,Avila-Rodriguez, M. F.,Tarasov, V. V.,Barreto, G. E.,Klochkov, S. G.,Bachurin, S. O.,Aliev, G. (2017) Nanotechnology for Alzheimer Disease. Curr Alzheimer Rescurr Alzheimer Res :1182-1189
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Diabetes Mellitus and Male Aging: Pharmacotherapeutics and Clinical Implications
Putta, S.,Peluso, I.,Yarla, N. S.,Kilari, E. K.,Bishayee, A.,Lu, D. Y.,Barreto, G. E.,Ashraf, G. M.,Scotti, L.,Scotti, M. T.,Singla, R. K.,Alexiou, T.,Atanasov, A. G.,Tarasov, V. V.,Bramhachari, P. V.,Imandi, S. B.,Chintala, M.,Sharma, B.,Reale, M.,Filosa, R.,Aliev, G.,Kamal, M. A. (2017) Diabetes Mellitus and Male Aging: Pharmacotherapeutics and Clinical Implications. Curr Pharm Descurr Pharm Des :4475-4483
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Is VEGF a Key Target of Cotinine and Other Potential Therapies Against Alzheimer Disease?
Echeverria, V.,Barreto, G. E.,Avila-Rodriguezc, M.,Tarasov, V. V.,Aliev, G. (2017) Is VEGF a Key Target of Cotinine and Other Potential Therapies Against Alzheimer Disease?. Curr Alzheimer Rescurr Alzheimer Res :1155-1163
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Genomics and epigenomics of tumor and aging cells
Aliev, G.;Barreto, G.E.;Cacabelos, R.; (2017) Genomics and epigenomics of tumor and aging cells. Current Genomics
Read moreMitochondrial Permeability Transition Pore as a Suitable Targ e t for Neuroprotective Agents Against Alzheimer's Disease
Shevtsova, E. F.,Vinogradova, D. V.,Neganova, M. E.,Avila-Rodriguez, M.,Ashraf, G. M.,Barreto, G. E.,Bachurin, S. O.,Aliev, G. (2017) Mitochondrial Permeability Transition Pore as a Suitable Targ e t for Neuroprotective Agents Against Alzheimer's Disease. Cns Neurol Disord Drug Targetscns Neurol Disord Drug Targets :677-685
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Medicinal Plants as Protective Strategies Against Parkinson's Disease
Mazo, N. A.,Echeverria, V.,Cabezas, R.,Avila-Rodriguez, M.,Tarasov, V. V.,Yarla, N. S.,Aliev, G.,Barreto, G. E. (2017) Medicinal Plants as Protective Strategies Against Parkinson's Disease. Curr Pharm Descurr Pharm Des :4180-4188
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Implications of farnesyltransferase and its inhibitors as a promising strategy for cancer therapy
Klochkov, S. G.,Neganova, M. E.,Yarla, N. S.,Parvathaneni, M.,Sharma, B.,Tarasov, V. V.,Barreto, G.,Bachurin, S. O.,Ashraf, G. M.,Aliev, G. (2017) Implications of farnesyltransferase and its inhibitors as a promising strategy for cancer therapy. Semin Cancer Biolsemin Cancer Biol
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SUR1 Receptor Interaction with Hesperidin and Linarin Predicts Possible Mechanisms of Action of Valeriana officinalis in Parkinson
Santos, G.,Giraldez-Alvarez, L. D.,Avila-Rodriguez, M.,Capani, F.,Galembeck, E.,Neto, A. G.,Barreto, G. E.,Andrade, B. (2016) SUR1 Receptor Interaction with Hesperidin and Linarin Predicts Possible Mechanisms of Action of Valeriana officinalis in Parkinson. Front Aging Neuroscifront Aging Neurosci :97-
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Targeting the Nicotinic Acetylcholine Receptors (nAChRs) in Astrocytes as a Potential Therapeutic Target in Parkinsonâs Disease
Juan Jurado-Coronel;Marco Avila-Rodriguez;Francisco Capani;Janneth Gonzalez;Valentina Moran;George Barreto; (2016) Targeting the Nicotinic Acetylcholine Receptors (nAChRs) in Astrocytes as a Potential Therapeutic Target in Parkinsonâs Disease. Current pharmaceutical design
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Role of microfluidics in blood-brain barrier permeability cell culture modeling: Relevance to CNS disorders
Rusanov, A.L.;Luzgina, N.G.;Barreto, G.E.;Aliev, G.; (2016) Role of microfluidics in blood-brain barrier permeability cell culture modeling: Relevance to CNS disorders. CNS & neurological disorders drug targets
Read moreIschemic Stroke and Six Genetic Variants in CRP, EPHX2, FGA, and NOTCH3 Genes: A Meta-Analysis
Gonzalez-Giraldo, Y.,Barreto, G. E.,Fava, C.,Forero, D. A. (2016) Ischemic Stroke and Six Genetic Variants in CRP, EPHX2, FGA, and NOTCH3 Genes: A Meta-Analysis. J Stroke Cerebrovasc Disj Stroke Cerebrovasc Dis :2284-9
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Metabolic Changes Following Perinatal Asphyxia: Role of Astrocytes and Their Interaction with Neurons
Logica, T.,Riviere, S.,Holubiec, M. I.,Castilla, R.,Barreto, G. E.,Capani, F. (2016) Metabolic Changes Following Perinatal Asphyxia: Role of Astrocytes and Their Interaction with Neurons. Front Aging Neuroscifront Aging Neurosci :116-
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Alterations in Glucose Metabolism on Cognition: A Possible Link Between Diabetes and Dementia
Rodrigo González-Reyes;Gjumrakch Aliev;Marco Avila-Rodrigues;George Barreto; (2016) Alterations in Glucose Metabolism on Cognition: A Possible Link Between Diabetes and Dementia. Current pharmaceutical design
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Role of Microfluidics in Blood-Brain Barrier Permeability Cell Culture Modeling: Relevance to CNS Disorders
Rusanov, A. L.,Luzgina, N. G.,Barreto, G. E.,Aliev, G. (2016) Role of Microfluidics in Blood-Brain Barrier Permeability Cell Culture Modeling: Relevance to CNS Disorders. Cns Neurol Disord Drug Targetscns Neurol Disord Drug Targets :301-9
Read moreImplication of green tea as a possible therapeutic approach for Parkinson disease
Jurado-Coronel, J.C.;Ãvila-Rodriguez, M.;Echeverria, V.;Hidalgo, O.A.;Gonzalez, J.;Aliev, G.;Barreto, G.E.; (2016) Implication of green tea as a possible therapeutic approach for Parkinson disease. CNS & neurological disorders drug targets
Read moreAlterations in glucose metabolism on cognition: A possible link between diabetes and dementia
González-Reyes, R.E.;Aliev, G.;Ãvila-Rodrigues, M.;Barreto, G.E.; (2016) Alterations in glucose metabolism on cognition: A possible link between diabetes and dementia. Current pharmaceutical design
Read moreInflammatory Mechanisms and Oxidative Stress as Key Factors Responsible for Progression of Neurodegeneration: Role of Brain Innate Immune System
Leszek, J.,Barreto, G. E.,Gasiorowski, K.,Koutsouraki, E.,Avila-Rodrigues, M.,Aliev, G. (2016) Inflammatory Mechanisms and Oxidative Stress as Key Factors Responsible for Progression of Neurodegeneration: Role of Brain Innate Immune System. Cns Neurol Disord Drug Targetscns Neurol Disord Drug Targets :329-36
Read moreRegulation of astroglia by gonadal steroid hormones under physiological and pathological conditions
Acaz-Fonseca, E.,Avila-Rodriguez, M.,Garcia-Segura, L. M.,Barreto, G. E. (2016) Regulation of astroglia by gonadal steroid hormones under physiological and pathological conditions. Prog Neurobiolprog Neurobiol :5-26
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Microglial dependent protective effects of neuroactive steroids
Lanussa, O.H.;Ãvila-Rodriguez, M.;GarcÃa-Segura, L.M.;González, J.;Echeverria, V.;Aliev, G.;Barreto, G.E.; (2016) Microglial dependent protective effects of neuroactive steroids. CNS & neurological disorders drug targets
Read moreNeuroprotective effects of the catalytic subunit of telomerase: A potential therapeutic target in the central nervous system
Gonzalez-Giraldo, Y.,Forero, D. A.,Echeverria, V.,Gonzalez, J.,Avila-Rodriguez, M.,Garcia-Segura, L. M.,Barreto, G. E. (2016) Neuroprotective effects of the catalytic subunit of telomerase: A potential therapeutic target in the central nervous system. Ageing Res Revageing Res Rev :37-45
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Approaches for the development of drugs for treatment of obesity and metabolic syndrome
Maksimov, M.L.;Svistunov, A.A.;Tarasov, V.V.;Chubarev, V.N.;Ãvila-Rodriguez, M.;Barreto, G.E.;Dralova, O.V.;Aliev, G.; (2016) Approaches for the development of drugs for treatment of obesity and metabolic syndrome. Current pharmaceutical design
Read moreMicroglial dependent protective effects of neuroactive steroids
Lanussa, O. H.,Avila-Rodriguez, M.,Garcia-Segura, L. M.,Gonzalez, J.,Echeverria, V.,Aliev, G.,Barreto, G. E. (2016) Microglial dependent protective effects of neuroactive steroids. Cns Neurol Disord Drug Targetscns Neurol Disord Drug Targets :242-9
Read moreInflammatory mechanisms and oxidative stress as key factors responsible for progression of neurodegeneration: Role of brain innate immune system
Leszek, J.;Barreto, G.E.;GÄ siorowski, K.;Koutsouraki, E.;Ãvila-Rodrigues, M.;Aliev, G.; (2016) Inflammatory mechanisms and oxidative stress as key factors responsible for progression of neurodegeneration: Role of brain innate immune system. CNS & neurological disorders drug targets
Read moreSystems biology study of mucopolysaccharidosis using a human metabolic reconstruction network
Salazar, D. A.,Rodriguez-Lopez, A.,Herreno, A.,Barbosa, H.,Herrera, J.,Ardila, A.,Barreto, G. E.,Gonzalez, J.,Almeciga-Diaz, C. J. (2016) Systems biology study of mucopolysaccharidosis using a human metabolic reconstruction network. Mol Genet Metabmol Genet Metab :129-39
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Ultrastructural analysis of olfactory ensheathing cells derived from olfactory bulb and nerve of neonatal and juvenile rats
Gomez, R. M.,Ghotme, K.,Botero, L.,Bernal, J. E.,Perez, R.,Barreto, G. E.,Bustos, R. H. (2016) Ultrastructural analysis of olfactory ensheathing cells derived from olfactory bulb and nerve of neonatal and juvenile rats. Neurosci Resneurosci Res :10-7
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Tibolone protects astrocytic cells from glucose deprivation through a mechanism involving estrogen receptor beta and the upregulation of neuroglobin expression
Avila-Rodriguez, M.,Garcia-Segura, L. M.,Hidalgo-Lanussa, O.,Baez, E.,Gonzalez, J.,Barreto, G. E. (2016) Tibolone protects astrocytic cells from glucose deprivation through a mechanism involving estrogen receptor beta and the upregulation of neuroglobin expression. Mol Cell Endocrinolmol Cell Endocrinol :35-46
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Implication of Green Tea as a Possible Therapeutic Approach for Parkinson Disease
Jurado-Coronel, J. C.,Avila-Rodriguez, M.,Echeverria, V.,Hidalgo, O. A.,Gonzalez, J.,Aliev, G.,Barreto, G. E. (2016) Implication of Green Tea as a Possible Therapeutic Approach for Parkinson Disease. Cns Neurol Disord Drug Targetscns Neurol Disord Drug Targets :292-300
Read moreMicroglial dependent protective effects of neuroactive steroids
Oscar Lanussa;Marco Ãvila-Rodriguez;Luis GarcÃa-Segura;Janneth González;Valentina Echeverria;Gjumrakch Aliev;George Barreto; (2016) Microglial dependent protective effects of neuroactive steroids. CNS & neurological disorders drug targets
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Approaches for the Development of Drugs for Treatment of Obesity and Metabolic Syndrome
Maksimov, M. L.,Svistunov, A. A.,Tarasov, V. V.,Chubarev, V. N.,Avila-Rodriguez, M.,Barreto, G. E.,Dralova, O. V.,Aliev, G. (2016) Approaches for the Development of Drugs for Treatment of Obesity and Metabolic Syndrome. Curr Pharm Descurr Pharm Des :895-903
Read moreUnsuspected Intrinsic Property of Melanin to Dissociate Water Can Be Used for the Treatment of CNS Diseases
Herrera, A. S.,del Carmen Arias Esparza, M.,Solis Arias, P. E.,Avila-Rodriguez, M.,Barreto, G. E.,Li, Y.,Bachurin, S. O.,Aliev, G. (2016) Unsuspected Intrinsic Property of Melanin to Dissociate Water Can Be Used for the Treatment of CNS Diseases. Cns Neurol Disord Drug Targetscns Neurol Disord Drug Targets :135-40
Read moreA synopsis on the linkage between age-related dementias and vascular disorders
Sandesh Chibber;Athanasios Alexiou;Mohammed Alama;George Barreto;Gjumrakch Aliev;Ghulam Ashraf; (2016) A synopsis on the linkage between age-related dementias and vascular disorders. CNS & neurological disorders drug targets
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Targeting the Nicotinic Acetylcholine Receptors (nAChRs) in Astrocytes as a Potential Therapeutic Target in Parkinson's Disease
Jurado-Coronel, J. C.,Avila-Rodriguez, M.,Capani, F.,Gonzalez, J.,Moran, V. E.,Barreto, G. E. (2016) Targeting the Nicotinic Acetylcholine Receptors (nAChRs) in Astrocytes as a Potential Therapeutic Target in Parkinson's Disease. Curr Pharm Descurr Pharm Des :1305-11
Read moreGrowth Factors and Astrocytes Metabolism: Possible Roles for Platelet Derived Growth Factor
Cabezas, R.,Avila-Rodriguez, M.,Vega-Vela, N. E.,Echeverria, V.,Gonzalez, J.,Hidalgo, O. A.,Santos, A. B.,Aliev, G.,Barreto, G. E. (2016) Growth Factors and Astrocytes Metabolism: Possible Roles for Platelet Derived Growth Factor. Med Chemmed Chem :204-10
Read moreA synopsis on the linkage between age-related dementias and vascular disorders
Chibber, S.,Alexiou, A.,Alama, M. N.,Barreto, G. E.,Aliev, G.,Ashraf, G. M. (2016) A synopsis on the linkage between age-related dementias and vascular disorders. Cns Neurol Disord Drug Targetscns Neurol Disord Drug Targets :250-8
Read moreA synopsis on the linkage between age-related dementias and vascular disorders
Chibber, S.;Alexiou, A.;Alama, M.N.;Barreto, G.E.;Aliev, G.;Ashraf, G.M.; (2016) A synopsis on the linkage between age-related dementias and vascular disorders. CNS & neurological disorders drug targets
Read moreAlterations in Glucose Metabolism on Cognition: A Possible Link Between Diabetes and Dementia
Gonzalez-Reyes, R. E.,Aliev, G.,Avila-Rodrigues, M.,Barreto, G. E. (2016) Alterations in Glucose Metabolism on Cognition: A Possible Link Between Diabetes and Dementia. Curr Pharm Descurr Pharm Des :812-8
Read moreTargeting the nicotinic acetylcholine receptors (nAChRs) in astrocytes as a potential therapeutic target in Parkinsonâs disease
Jurado-Coronel, J.C.;Ãvila-Rodriguez, M.;Capani, F.;Gonzalez, J.;Morán, V.E.;Barreto, G.E.; (2016) Targeting the nicotinic acetylcholine receptors (nAChRs) in astrocytes as a potential therapeutic target in Parkinsonâs disease. Current pharmaceutical design
Read moreMeta-analysis of Telomere Length in Alzheimer's Disease
Forero, D. A.,Gonzalez-Giraldo, Y.,Lopez-Quintero, C.,Castro-Vega, L. J.,Barreto, G. E.,Perry, G. (2016) Meta-analysis of Telomere Length in Alzheimer's Disease. J Gerontol A Biol Sci Med Scij Gerontol A Biol Sci Med Sci :1069-73
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Implication of Green Tea as a Possible Therapeutic Approach for Parkinson Disease
Juan Jurado-Coronel;Marco Ãvila-Rodriguez;Valentina Echeverria;Oscar Hidalgo;Janneth Gonzalez;Gjumrakch Aliev;George Barreto; (2016) Implication of Green Tea as a Possible Therapeutic Approach for Parkinson Disease. CNS & neurological disorders drug targets
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Updates on the Production of Therapeutic Antibodies Using Human Hybridoma Technique
Glukhova, X. A.,Prusakova, O. V.,Trizna, J. A.,Zaripov, M. M.,Afanas'eva, G. V.,Glukhov, A. S.,Poltavtseva, R. A.,Ivanov, A. A.,Avila-Rodriguez, M.,Barreto, G. E.,Aliev, G.,Beletsky, I. P. (2016) Updates on the Production of Therapeutic Antibodies Using Human Hybridoma Technique. Curr Pharm Descurr Pharm Des :870-8
Read moreUpdates on the production of therapeutic antibodies using human hybridoma technique
Glukhova, X.A.;Prusakova, O.V.;Trizna, J.A.;Zaripov, M.M.;AfanasâEva, G.V.;Glukhov, A.S.;Poltavtseva, R.A.;Ivanov, A.A.;Avila-Rodriguez, M.;Barreto, G.E.;Aliev, G.;Beletsky, I.P.; (2016) Updates on the production of therapeutic antibodies using human hybridoma technique. Current pharmaceutical design
Read moreAntifertility activity of lac (Laccifer lacca Kerr.) in female wistar rat model
Perveen, A.;Barreto, G.E.;Jahan, N.;Wadud, A.;Tanwir Alam, M.;Ashraf, G.M.;Aliev, G.; (2016) Antifertility activity of lac (Laccifer lacca Kerr.) in female wistar rat model. Immunology, Endocrine And Metabolic Agents In Medicinal Chemistry
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Computational analysis and functional prediction of ubiquitin hypothetical protein: A possible target in parkinson disease
Barragán-Osorio, L.;Giraldo, G.;Alméciga-Diaz, C.J.;Aliev, G.;Barreto, G.E.;Gonzalez, J.; (2016) Computational analysis and functional prediction of ubiquitin hypothetical protein: A possible target in parkinson disease. Central nervous system agents in medicinal chemistry
Read moreRole of Microfluidics in Blood-Brain Barrier Permeability Cell Culture Modeling: Relevance to CNS Disorders
Alexander Rusanov;Natalia Luzgina;George Barreto;Gjumrakch Aliev; (2016) Role of Microfluidics in Blood-Brain Barrier Permeability Cell Culture Modeling: Relevance to CNS Disorders. CNS & neurological disorders drug targets
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Neuroinflammation: A Therapeutic Target of Cotinine for the Treatment of Psychiatric Disorders?
Echeverria, V.,Grizzell, J. A.,Barreto, G. E. (2016) Neuroinflammation: A Therapeutic Target of Cotinine for the Treatment of Psychiatric Disorders?. Curr Pharm Descurr Pharm Des :1324-33
Read moreNeuroinflammation: A therapeutic target of cotinine for the treatment of psychiatric disorders?
Echeverria, V.;Grizzell, J.A.;Barreto, G.E.; (2016) Neuroinflammation: A therapeutic target of cotinine for the treatment of psychiatric disorders?. Current pharmaceutical design
Read moreNovel Approaches in Astrocyte Protection: from Experimental Methods to Computational Approaches
Garzon, D.,Cabezas, R.,Vega, N.,Avila-Rodriguez, M.,Gonzalez, J.,Gomez, R. M.,Echeverria, V.,Aliev, G.,Barreto, G. E. (2016) Novel Approaches in Astrocyte Protection: from Experimental Methods to Computational Approaches. J Mol Neuroscij Mol Neurosci :483-92
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Growth factors and astrocytes metabolism: Possible roles for platelet derived growth factor
Cabezas, R.;Avila-Rodriguez, M.;Vega-Vela, N.E.;Echeverria, V.;González, J.;Hidalgo, O.A.;Santos, A.B.;Aliev, G.;Barreto, G.E.; (2016) Growth factors and astrocytes metabolism: Possible roles for platelet derived growth factor. Journal Of Medicinal Chemistry
Read morePrediction of glycation sites: New insights from protein structural analysis
Sáenz-Suárez, H.;Poutou-Piñales, R.A.;González-Santos, J.;Barreto, G.E.;Rieto-Navarrera, L.P.;Sáenz-Moreno, J.A.;Landázuri, P.;Barrera-Avellaneda, L.A.; (2016) Prediction of glycation sites: New insights from protein structural analysis. Turkish Journal Of Biology
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Testosterone Protects Mitochondrial Function and Regulates Neuroglobin Expression in Astrocytic Cells Exposed to Glucose Deprivation
Toro-Urrego, N.,Garcia-Segura, L. M.,Echeverria, V.,Barreto, G. E. (2016) Testosterone Protects Mitochondrial Function and Regulates Neuroglobin Expression in Astrocytic Cells Exposed to Glucose Deprivation. Front Aging Neuroscifront Aging Neurosci :152-
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Approaches for the Development of Drugs for Treatment of Obesity and Metabolic Syndrome
Maksim Maksimov;Andrey Svistunov;Vadim Tarasov;Vladimir Chubarev;Marco Ãvila-Rodriguez;George Barreto;Olga Dralova;Gjumrakch Aliev; (2016) Approaches for the Development of Drugs for Treatment of Obesity and Metabolic Syndrome. Current pharmaceutical design
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Unsuspected intrinsic property of melanin to dissociate water can be used for the treatment of CNS diseases
Herrera, A.S.;Esparza, M.C.A.;Arias, P.E.S.;Ãvila-Rodriguez, M.;Barreto, G.E.;Li, Y.;Bachurin, S.O.;Aliev, G.; (2016) Unsuspected intrinsic property of melanin to dissociate water can be used for the treatment of CNS diseases. CNS & neurological disorders drug targets
Read moreComputational Analysis and Functional Prediction of Ubiquitin Hypothetical Protein: A Possible Target in Parkinson Disease
Barragan-Osorio, L.,Giraldo, G.,Almeciga-Diaz, C. J.,Aliev, G.,Barreto, G. E.,Gonzalez, J. (2015) Computational Analysis and Functional Prediction of Ubiquitin Hypothetical Protein: A Possible Target in Parkinson Disease. Cent Nerv Syst Agents Med Chemcent Nerv Syst Agents Med Chem :4-11
Read moreNicotine-Derived Compounds as Therapeutic Tools Against Post-Traumatic Stress Disorder
Barreto, G. E.,Yarkov, A.,Avila-Rodriguez, M.,Aliev, G.,Echeverria, V. (2015) Nicotine-Derived Compounds as Therapeutic Tools Against Post-Traumatic Stress Disorder. Curr Pharm Descurr Pharm Des :3589-95
Read moreNitric Oxide-Dependent Oxidative Stress Induced Mitochondrial DNA Overproliferation and Deletion in the Context of Cancer and Alzheimer Disease
Aliev Gjumrakch;Barreto George E.; (2015) Nitric Oxide-Dependent Oxidative Stress Induced Mitochondrial DNA Overproliferation and Deletion in the Context of Cancer and Alzheimer Disease. Frontiers In Cellular Neuroscience
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The innate immunity in alzheimer disease-relevance to pathogenesis and therapy
Blach-Olszewska, Z.;Zaczynska, E.;Gustaw-Rothenberg, K.;Avila-Rodrigues, M.;Barreto, G.E.;Leszek, J.;Aliev, G.; (2015) The innate immunity in alzheimer disease-relevance to pathogenesis and therapy. Current pharmaceutical design
Read moreNicotine analogues as potential therapeutic agents in Parkinsonâs disease by targeting nicotinic acetylcholine receptors (nAChRs) in astrocytes
Jurado-Coronel Juan;Gonzalez Janneth;Echeverria Moran Valentina;Barreto George E.; (2015) Nicotine analogues as potential therapeutic agents in Parkinsonâs disease by targeting nicotinic acetylcholine receptors (nAChRs) in astrocytes. Frontiers In Cellular Neuroscience
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Nicotine-derived compounds as therapeutic tools against post-traumatic stress disorder
Barreto, G.E.;Yarkov, A.;Ãvila-Rodriguez, M.;Aliev, G.;Echeverria, V.; (2015) Nicotine-derived compounds as therapeutic tools against post-traumatic stress disorder. Current pharmaceutical design
Read moreImplications of astrocytes in mediating the protective effects of Selective Estrogen Receptor Modulators upon brain damage
Martin Cynthia;Gonzalez Janneth;Barreto George E.; (2015) Implications of astrocytes in mediating the protective effects of Selective Estrogen Receptor Modulators upon brain damage. Frontiers In Cellular Neuroscience
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Nicotine-Derived Compounds as Therapeutic Tools Against Post-Traumatic Stress Disorder
George Barreto;Alexander Yarkov;Marcos Avila-Rodriguez;Gjumrakch Aliev;Valentina Echeverria; (2015) Nicotine-Derived Compounds as Therapeutic Tools Against Post-Traumatic Stress Disorder. Current pharmaceutical design
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Neuroprotection by estrogenic compounds following inflammatory insult in the brain
Lanussa Oscar;Ãvila-Rodriguez Marcos;Gonzalez Janneth;Garcia-Segura Luis;Barreto George E.; (2015) Neuroprotection by estrogenic compounds following inflammatory insult in the brain. Frontiers In Cellular Neuroscience
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The Innate Immunity in Alzheimer Disease- Relevance to Pathogenesis and Therapy
Zofia Blach-Olszewska;Ewa Zaczynska;Kasia Gustaw-Rothenberg;Marco Avila-Rodrigues;George Barreto;Jerzy Leszek;Gjumrakch Aliev; (2015) The Innate Immunity in Alzheimer Disease- Relevance to Pathogenesis and Therapy. Current pharmaceutical design
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Effects of nicotine analogs in an experimental model of Parkinson´s disease: role of CDK5 on dopamine release
Gonzalez Yeimy;Barreto George E.; (2015) Effects of nicotine analogs in an experimental model of Parkinson´s disease: role of CDK5 on dopamine release. Frontiers In Cellular Neuroscience
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Editorial on Cerebral endothelial and glial cells are more than bricks in the Great Wall of the brain: insights into the way the blood-brain barrier actually works (celebrating the centenary of Goldman's experiments)
Garcia-Martin, E.,Barreto, G. E.,Agundez, J. A.,Guedes, R. C.,El-Bacha, R. S. (2015) Editorial on Cerebral endothelial and glial cells are more than bricks in the Great Wall of the brain: insights into the way the blood-brain barrier actually works (celebrating the centenary of Goldman's experiments). Front Cell Neuroscifront Cell Neurosci :128-
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Nanoparticles as Alternative Strategies for Drug Delivery to the Alzheimer Brain: Electron Microscopy Ultrastructural Analysis
Aliev, G.,Daza, J.,Herrera, A. S.,del Carmen Arias Esparza, M.,Morales, L.,Echeverria, V.,Bachurin, S. O.,Barreto, G. E. (2015) Nanoparticles as Alternative Strategies for Drug Delivery to the Alzheimer Brain: Electron Microscopy Ultrastructural Analysis. Cns Neurol Disord Drug Targetscns Neurol Disord Drug Targets :1235-42
Read moreConjugates of gamma-Carbolines and Phenothiazine as new selective inhibitors of butyrylcholinesterase and blockers of NMDA receptors for Alzheimer Disease
Makhaeva, G. F.,Lushchekina, S. V.,Boltneva, N. P.,Sokolov, V. B.,Grigoriev, V. V.,Serebryakova, O. G.,Vikhareva, E. A.,Aksinenko, A. Y.,Barreto, G. E.,Aliev, G.,Bachurin, S. O. (2015) Conjugates of gamma-Carbolines and Phenothiazine as new selective inhibitors of butyrylcholinesterase and blockers of NMDA receptors for Alzheimer Disease. Sci Repsci Rep :13164-
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Mechanisms of PDGFRalpha promiscuity and PDGFRbeta specificity in association with PDGFB
Torrente, D.,Cabezas, R.,Avila, M.,Sanchez, Y.,Morales, L.,Ashraf, G. M.,Barreto, G. E.,Gonzalez, J.,Aliev, G. (2015) Mechanisms of PDGFRalpha promiscuity and PDGFRbeta specificity in association with PDGFB. Front Biosci (Elite Ed)Front Biosci (Elite Ed) :434-46
Read moreNanoparticles as alternative strategies for drug delivery to the Alzheimer brain: Electron microscopy ultrastructural analysis
Aliev, G.;Daza, J.;Herrera, A.S.;Esparza, M.D.C.A.;Morales, L.;Echeverria, V.;Bachurin, S.O.;Barreto, G.E.; (2015) Nanoparticles as alternative strategies for drug delivery to the Alzheimer brain: Electron microscopy ultrastructural analysis. CNS & neurological disorders drug targets
Read moreBiological Activities of QIAPI 1 as a Melanin Precursor and Its Therapeutic Effects in Wistar Rats Exposed to Arsenic Poisoning
Solis-Herrera, A.,Ashraf, G. M.,del, C. A. Esparza M.,Arias, R. I.,Bachurin, S. O.,Barreto, G. E.,Aliev, G. (2015) Biological Activities of QIAPI 1 as a Melanin Precursor and Its Therapeutic Effects in Wistar Rats Exposed to Arsenic Poisoning. Cent Nerv Syst Agents Med Chemcent Nerv Syst Agents Med Chem :99-108
Read moreThe Innate Immunity in Alzheimer Disease- Relevance to Pathogenesis and Therapy
Blach-Olszewska, Z.,Zaczynska, E.,Gustaw-Rothenberg, K.,Avila-Rodrigues, M.,Barreto, G. E.,Leszek, J.,Aliev, G. (2015) The Innate Immunity in Alzheimer Disease- Relevance to Pathogenesis and Therapy. Curr Pharm Descurr Pharm Des :3582-8
Read moreNeuroprotective effects of hypothermia on synaptic actin cytoskeletal changes induced by perinatal asphyxia
Muñiz, J.;Romero, J.;Holubiec, M.;Barreto, G.;González, J.;Saint-Martin, M.;Blanco, E.;Carlos Cavicchia, J.;Castilla, R.;Capani, F.; (2014) Neuroprotective effects of hypothermia on synaptic actin cytoskeletal changes induced by perinatal asphyxia. Brain research
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Computational Insights of the Interaction among Sea Anemones Neurotoxins and Kv1.3 Channel
Sabogal-Arango, A.,Barreto, G. E.,Ramirez-Sanchez, D.,Gonzalez-Mendoza, J.,Barreto, V.,Morales, L.,Gonzalez, J. (2014) Computational Insights of the Interaction among Sea Anemones Neurotoxins and Kv1.3 Channel. Bioinform Biol Insightsbioinform Biol Insights :73-81
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In silico docking reveals possible Riluzole binding sites on Nav1.6 sodium channel: implications for drug design strategy on Amyotrophic Lateral Sclerosis
Sierra Omar;González Janneth;Barreto George; (2014) In silico docking reveals possible Riluzole binding sites on Nav1.6 sodium channel: implications for drug design strategy on Amyotrophic Lateral Sclerosis. Frontiers In Neuroinformatics
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Treatment of sleeping disorders should be considered in clinical management of Parkinson's disease
Dos Santos, A. B.,Barreto, G. E.,Kohlmeier, K. A. (2014) Treatment of sleeping disorders should be considered in clinical management of Parkinson's disease. Front Aging Neuroscifront Aging Neurosci :273-
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Paracrine factors of human mesenchymal stem cells increase wound closure and reduce reactive oxygen species production in a traumatic brain injury in vitro model
Torrente, D.,Avila, M. F.,Cabezas, R.,Morales, L.,Gonzalez, J.,Samudio, I.,Barreto, G. E. (2014) Paracrine factors of human mesenchymal stem cells increase wound closure and reduce reactive oxygen species production in a traumatic brain injury in vitro model. Hum Exp Toxicolhum Exp Toxicol :673-84
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Selective estrogen receptor modulators regulate reactive microglia after penetrating brain injury
Barreto, G. E.,Santos-Galindo, M.,Garcia-Segura, L. M. (2014) Selective estrogen receptor modulators regulate reactive microglia after penetrating brain injury. Front Aging Neuroscifront Aging Neurosci :132-
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Beneficial effects of nicotine, cotinine and its metabolites as potential agents for Parkinson's disease
Barreto, G. E.,Iarkov, A.,Moran, V. E. (2014) Beneficial effects of nicotine, cotinine and its metabolites as potential agents for Parkinson's disease. Front Aging Neuroscifront Aging Neurosci :340-
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Dual role of astrocytes in perinatal asphyxia injury and neuroprotection
Romero, J.,Muniz, J.,Logica Tornatore, T.,Holubiec, M.,Gonzalez, J.,Barreto, G. E.,Guelman, L.,Lillig, C. H.,Blanco, E.,Capani, F. (2014) Dual role of astrocytes in perinatal asphyxia injury and neuroprotection. Neurosci Lettneurosci Lett :42-6
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Cortical spreading depression and mitochondrial dysfunction with aging: lessons from ethanol abuse
Barreto, G. E.,Capani, F.,Cabezas, R. (2014) Cortical spreading depression and mitochondrial dysfunction with aging: lessons from ethanol abuse. Front Aging Neuroscifront Aging Neurosci :117-
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Increased calcium influx triggers and accelerates cortical spreading depression in vivo in male adult rats
Torrente, D.,Mendes-da-Silva, R. F.,Lopes, A. A.,Gonzalez, J.,Barreto, G. E.,Guedes, R. C. (2014) Increased calcium influx triggers and accelerates cortical spreading depression in vivo in male adult rats. Neurosci Lettneurosci Lett :87-90
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Computational modeling and preliminary iroN, fepA, and cirA gene expression in Salmonella Enteritidis under iron-deficiency-induced conditions
Zárate-Bonilla, L.J.;Del Portillo, P.;Sáenz-Suárez, H.;Gonzáles-Santos, J.;Barreto-Sampaio, G.E.;Poutou-Piñales, R.A.;Rey, A.F.;Rey, J.G.; (2014) Computational modeling and preliminary iroN, fepA, and cirA gene expression in Salmonella Enteritidis under iron-deficiency-induced conditions. Poultry Science
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Cortical spreading depression in traumatic brain injuries: is there a role for astrocytes?
Torrente, D.,Cabezas, R.,Avila, M. F.,Garcia-Segura, L. M.,Barreto, G. E.,Guedes, R. C. (2014) Cortical spreading depression in traumatic brain injuries: is there a role for astrocytes?. Neurosci Lettneurosci Lett :2-6
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Structural insights from GRP78-NF-kappaB binding interactions: a computational approach to understand a possible neuroprotective pathway in brain injuries
Avila, M. F.,Torrente, D.,Cabezas, R.,Morales, L.,Garcia-Segura, L. M.,Gonzalez, J.,Barreto, G. E. (2014) Structural insights from GRP78-NF-kappaB binding interactions: a computational approach to understand a possible neuroprotective pathway in brain injuries. J Theor Biolj Theor Biol :43-51
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Astrocytic modulation of blood brain barrier: perspectives on Parkinson's disease
Cabezas, R.,Avila, M.,Gonzalez, J.,El-Bacha, R. S.,Baez, E.,Garcia-Segura, L. M.,Jurado Coronel, J. C.,Capani, F.,Cardona-Gomez, G. P.,Barreto, G. E. (2014) Astrocytic modulation of blood brain barrier: perspectives on Parkinson's disease. Front Cell Neuroscifront Cell Neurosci :211-
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Leishmania braziliensis replication protein A subunit 1: molecular modelling, protein expression and analysis of its affinity for both DNA and RNA
Nocua, P. A.,Ramirez, C. A.,Barreto, G. E.,Gonzalez, J.,Requena, J. M.,Puerta, C. J. (2014) Leishmania braziliensis replication protein A subunit 1: molecular modelling, protein expression and analysis of its affinity for both DNA and RNA. Parasit Vectorsparasit Vectors :573-
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Computational insights of the interaction among sea anemones neurotoxins and Kv1.3 channel
Sabogal-Arango, A.;Barreto, G.E.;RamÃrez-Sánchez, D.;González-Mendoza, J.;Barreto, V.;Morales, L.;González, J.; (2014) Computational insights of the interaction among sea anemones neurotoxins and Kv1.3 channel. Bioinformatics And Biology Insights
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Using a computational human metabolic reconstruction on the study of mucopolysaccharidosis
Diego Salazar;Alexander RodrÃguez-López;George E. Barreto;Janeth González;Carlos J. Almeciga-Diaz; (2014) Using a computational human metabolic reconstruction on the study of mucopolysaccharidosis. Molecular Genetics And Metabolism
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Introduction. Astrocytes in the injured brain: is gliosis adaptive or maladaptive?
Barreto, G.E.;Black, J.A.; (2014) Introduction. Astrocytes in the injured brain: is gliosis adaptive or maladaptive?. Neuroscience Letters
Read moreIntegrative Approach for Computationally Inferring Interactions between the Alpha and Beta Subunits of the Calcium-Activated Potassium Channel (BK): a Docking Study
Gonzalez, J.,Galvez, A.,Morales, L.,Barreto, G. E.,Capani, F.,Sierra, O.,Torres, Y. (2013) Integrative Approach for Computationally Inferring Interactions between the Alpha and Beta Subunits of the Calcium-Activated Potassium Channel (BK): a Docking Study. Bioinform Biol Insightsbioinform Biol Insights :73-82
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Relationship between quality of sleep and cognitive function in patients with parkinson's disease,Relação entre qualidade do sono e funções cognitivas em pacientes com doença de parkinson
Dos Santos, A.B.;Campos, S.L.;Ribeiro, S.;Morales, L.;Gonzalez, J.;Dos Santos Trindade, J.;Barreto, G.E.; (2013) Relationship between quality of sleep and cognitive function in patients with parkinson's disease,Relação entre qualidade do sono e funções cognitivas em pacientes com doença de parkinson. Universitas Scientiarum
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Selective activation of protein kinase C in mitochondria is neuroprotective in vitro and reduces focal ischemic brain injury in mice
Sun, X.,Budas, G. R.,Xu, L.,Barreto, G. E.,Mochly-Rosen, D.,Giffard, R. G. (2013) Selective activation of protein kinase C in mitochondria is neuroprotective in vitro and reduces focal ischemic brain injury in mice. J Neurosci Resj Neurosci Res :799-807
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Protein LIC10494 of Leptospira interrogans serovar Copenhageni: Structural model and associated functional regions,ProteÃna LIC10494 de Leptospira interrogans serovar Copenhageni: Modelo estructural y regiones funcionales asociadas
Barreto, L.V.;Barreto, G.E.;Morales, L.;Acevedo, O.E.;Santos, J.G.; (2012) Protein LIC10494 of Leptospira interrogans serovar Copenhageni: Structural model and associated functional regions,ProteÃna LIC10494 de Leptospira interrogans serovar Copenhageni: Modelo estructural y regiones funcionales asociadas. Universitas Scientiarum
Read moreEffects of natural antioxidants in neurodegenerative disease
Albarracin, S. L.,Stab, B.,Casas, Z.,Sutachan, J. J.,Samudio, I.,Gonzalez, J.,Gonzalo, L.,Capani, F.,Morales, L.,Barreto, G. E. (2012) Effects of natural antioxidants in neurodegenerative disease. Nutr Neuroscinutr Neurosci :1-9
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ProteÃna LIC10494 de Leptospira interrogans serovar Copenhageni: modelo estructural y regiones funcionales asociadas
Leidy Viviana Barreto;George EmÃlio Barreto;Ludis Morales;Orlando Emilio Acevedo;Janneth González Santos; (2012) ProteÃna LIC10494 de Leptospira interrogans serovar Copenhageni: modelo estructural y regiones funcionales asociadas. Universitas Scientiarum
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Mitochondrial functions in astrocytes: neuroprotective implications from oxidative damage by rotenone
Cabezas, R.,El-Bacha, R. S.,Gonzalez, J.,Barreto, G. E. (2012) Mitochondrial functions in astrocytes: neuroprotective implications from oxidative damage by rotenone. Neurosci Resneurosci Res :80-90
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Effects of heat shock protein 72 (Hsp72) on evolution of astrocyte activation following stroke in the mouse
Barreto, G. E.,White, R. E.,Xu, L.,Palm, C. J.,Giffard, R. G. (2012) Effects of heat shock protein 72 (Hsp72) on evolution of astrocyte activation following stroke in the mouse. Exp Neurolexp Neurol :284-96
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Effects of perinatal asphyxia on rat striatal cytoskeleton
Saraceno, G.E.;Ayala, M.V.;Badorrey, M.S.;Holubiec, M.;Romero, J.I.;Galeano, P.;Barreto, G.;Giraldez-Alvárez, L.D.;Kölliker-fres, R.;Coirini, H.;Capani, F.; (2012) Effects of perinatal asphyxia on rat striatal cytoskeleton. Synapse
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Early changes in the synapses of the neostriatum induced by perinatal asphyxia
Grimaldi, M.;Romer, I.;González de Apodaca, M.T.;Iturbe, L.;Catania, I.D.;González, J.;Kolliker-Fres, R.;Barreto, G.;Capani, F.; (2012) Early changes in the synapses of the neostriatum induced by perinatal asphyxia. Nutritional Neuroscience
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In silico docking reveals possible Riluzole binding sites on Nav1.6 sodium channel: implications for amyotrophic lateral sclerosis therapy
Sierra Bello, O.,Gonzalez, J.,Capani, F.,Barreto, G. E. (2012) In silico docking reveals possible Riluzole binding sites on Nav1.6 sodium channel: implications for amyotrophic lateral sclerosis therapy. J Theor Biolj Theor Biol :53-63
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Cellular and molecular mechanisms of antioxidants in Parkinson's disease
Sutachan, J. J.,Casas, Z.,Albarracin, S. L.,Stab, B. R., 2nd,Samudio, I.,Gonzalez, J.,Morales, L.,Barreto, G. E. (2012) Cellular and molecular mechanisms of antioxidants in Parkinson's disease. Nutr Neuroscinutr Neurosci :120-6
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Astrocytes: targets for neuroprotection in stroke
Barreto, G.,White, R. E.,Ouyang, Y.,Xu, L.,Giffard, R. G. (2011) Astrocytes: targets for neuroprotection in stroke. Cent Nerv Syst Agents Med Chemcent Nerv Syst Agents Med Chem :164-73
Read moreAstrocytes: Targets for neuroprotection in stroke
Barreto, G.;White, R.E.;Ouyang, Y.;Xu, L.;Giffard, R.G.; (2011) Astrocytes: Targets for neuroprotection in stroke. Central nervous system agents in medicinal chemistry
Read moreLong-lasting effects of perinatal asphyxia on exploration, memory and incentive downshift
Galeano, P.,Blanco Calvo, E.,Madureira de Oliveira, D.,Cuenya, L.,Kamenetzky, G. V.,Mustaca, A. E.,Barreto, G. E.,Giraldez-Alvarez, L. D.,Milei, J.,Capani, F. (2011) Long-lasting effects of perinatal asphyxia on exploration, memory and incentive downshift. Int J Dev Neurosciint J Dev Neurosci :609-19
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Heat shock protein 72 overexpression prevents early postoperative memory decline after orthopedic surgery under general anesthesia in mice
Vizcaychipi, M. P.,Xu, L.,Barreto, G. E.,Ma, D.,Maze, M.,Giffard, R. G. (2011) Heat shock protein 72 overexpression prevents early postoperative memory decline after orthopedic surgery under general anesthesia in mice. Anesthesiologyanesthesiology :891-900
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Increased brain injury and worsened neurological outcome in interleukin-4 knockout mice after transient focal cerebral ischemia
Xiong, X.,Barreto, G. E.,Xu, L.,Ouyang, Y. B.,Xie, X.,Giffard, R. G. (2011) Increased brain injury and worsened neurological outcome in interleukin-4 knockout mice after transient focal cerebral ischemia. Strokestroke :2026-32
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Paullinia cupana Mart. var. Sorbilis protects human dopaminergic neuroblastoma SH-SY5Y cell line against rotenone-induced cytotoxicity
De Oliveira, D.M.;Barreto, G.;Galeano, P.;Romero, J.I.;Holubiec, M.I.;Badorrey, M.S.;Capani, F.;Giraldez Alvarez, L.D.; (2011) Paullinia cupana Mart. var. Sorbilis protects human dopaminergic neuroblastoma SH-SY5Y cell line against rotenone-induced cytotoxicity. Human & Experimental Toxicology
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Protein ubiquitination in postsynaptic densities after hypoxia in rat neostriatum is blocked by hypothermia
Capani, F.;Saraceno, G.E.;Botti, V.;Aon-Bertolino, L.;Madureira de Oliveira, D.;Barreto, G.;Galeano, P.;Giraldez-Alvarez, L.D.;Coirini, H.; (2009) Protein ubiquitination in postsynaptic densities after hypoxia in rat neostriatum is blocked by hypothermia. Experimental Neurology
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The role of catechols and free radicals in benzene toxicity: An oxidative DNA damage pathway
Barreto, G.;Madureira, D.;Capani, F.;Aon-Bertolino, L.;Saraceno, E.;Alvarez-Giraldez, L.D.; (2009) The role of catechols and free radicals in benzene toxicity: An oxidative DNA damage pathway. Environmental And Molecular Mutagenesis
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Selective estrogen receptor modulators decrease reactive astrogliosis in the injured brain: effects of aging and prolonged depletion of ovarian hormones
Barreto, G.,Santos-Galindo, M.,Diz-Chaves, Y.,Pernia, O.,Carrero, P.,Azcoitia, I.,Garcia-Segura, L. M. (2009) Selective estrogen receptor modulators decrease reactive astrogliosis in the injured brain: effects of aging and prolonged depletion of ovarian hormones. Endocrinologyendocrinology :5010-5
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Cytoprotective effect of valeriana officinalis extract on an in vitro experimental model of parkinson disease
De Oliveria, D.M.;Barreto, G.;De Andrade, D.V.G.;Saraceno, E.;Aon-Bertolino, L.;Capani, F.;Dos Santos El Bachá, R.;Giraldez, L.D.; (2009) Cytoprotective effect of valeriana officinalis extract on an in vitro experimental model of parkinson disease. Neurochemical Research
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Effects of the extract of Anemopaegma mirandum (Catuaba) on Rotenone-induced apoptosis in human neuroblastomas SH-SY5Y cells
De Andrade, D.V.G.;Madureira de Oliveria, D.;Barreto, G.;Bertolino, L.-A.;Saraceno, E.;Capani, F.;Giraldez, L.D.; (2008) Effects of the extract of Anemopaegma mirandum (Catuaba) on Rotenone-induced apoptosis in human neuroblastomas SH-SY5Y cells. Brain research
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Investigation of toxic factors affecting cells of rat brains exposed to 3-methylcatechol
Barreto, G.E.S.;De Oliveira, E.S.;De Villar, F.A.G.A.;Dos Santos, G.S.;Lima, R.M.F.;Costa, S.L.;Costa, M.D.F.D.;Egito, E.S.T.;El-Bachá, R.S.; (2007) Investigation of toxic factors affecting cells of rat brains exposed to 3-methylcatechol. Brazilian Archives Of Biology And Technology
Read moreTestosterone decreases reactive astroglia and reactive microglia after brain injury in male rats: role of its metabolites, oestradiol and dihydrotestosterone
Barreto, G.,Veiga, S.,Azcoitia, I.,Garcia-Segura, L. M.,Garcia-Ovejero, D. (2007) Testosterone decreases reactive astroglia and reactive microglia after brain injury in male rats: role of its metabolites, oestradiol and dihydrotestosterone. Eur J Neuroscieur J Neurosci :3039-46
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Catechol inhibits FADH2-linked respiration in rat liver mitochondrial fraction.
Barreto, G.E.;dos Santos, G.S.;Egito, E.S.;El-Bachá, R.S.; (2005) Catechol inhibits FADH2-linked respiration in rat liver mitochondrial fraction.. Acta CirãºRgica Brasileira / Sociedade Brasileira Para Desenvolvimento Pesquisa Em Cirurgia
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Neuroprotection by Exogenous Estrogenic Compounds Following Traumatic Brain Injury
Lopez-Rodriguez, A.B.;Ãvila-Rodriguez, M.;Vega-Vela, N.E.;Capani, F.;Gonzalez, J.;GarcÃa-Segura, L.M.;Barreto, G.E.; (2015) Neuroprotection by Exogenous Estrogenic Compounds Following Traumatic Brain Injury. Estrogen Effects on Traumatic Brain Injury: Mechanisms of Neuroprotection and Repair
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Neuroprotection with Estradiol in Experimental Perinatal Asphyxia: A New Approach. A New Approach.
Barreto, G.;Saraceno, E.;Gonzalez, J.;Kolliker, R.;Castilla, R.;Capani, F.; (2015) Neuroprotection with Estradiol in Experimental Perinatal Asphyxia: A New Approach. A New Approach.. Estrogen Effects on Traumatic Brain Injury: Mechanisms of Neuroprotection and Repair
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Analysis of binding residues between PDGF-BB and epidermal growth factor receptor: A computational docking study
Cabezas, R.;Torrente, D.;Avila, M.F.;González, J.;Barreto, G.E.; (2014) Analysis of binding residues between PDGF-BB and epidermal growth factor receptor: A computational docking study. Advances in Intelligent Systems and Computing
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In silico analysis of iduronate 2 sulfatase mutations in Colombian patients with Hunter Syndrome (MPSII)
Galvis, J.;González, J.;Torrente, D.;Velasco, H.;Barreto, G.E.; (2014) In silico analysis of iduronate 2 sulfatase mutations in Colombian patients with Hunter Syndrome (MPSII). Advances in Intelligent Systems and Computing
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Structural and functional prediction of the hypothetical protein PA2481 in Pseudomonas aeruginosa Pao1
DÃaz, D.A.;Barreto, G.E.;Santos, J.G.; (2014) Structural and functional prediction of the hypothetical protein PA2481 in Pseudomonas aeruginosa Pao1. Advances in Intelligent Systems and Computing
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Regulación por andrógenos y estrógenos de la gliosis tras lesiones cerebrales en la rata
George E. Barreto (2009) Regulación por andrógenos y estrógenos de la gliosis tras lesiones cerebrales en la rata. Madrid, Spain : Universidad Complutense de Madrid
Read moreEstudo do efecto dos metabolitos do benzeno e tolueno sobre as mitocondrias cerebrais e hepáticas de ratos
George Barreto (2005) Estudo do efecto dos metabolitos do benzeno e tolueno sobre as mitocondrias cerebrais e hepáticas de ratos. Natal, Brazil : Universidade Federal de Rio Grande de Norte
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Mitochondrial KATP Channel and Dopaminergic Vulnerability Neurons in Parkinson's Disease
Gesivaldo Santos, Julita Maria Pereira Borges, Marcos Avilla-Rodriguez, Érika Pereira Rubio, Cattiúscia Batista Bromochenkel, Djalma Menezes Oliveira, Jane Lima dos Santos, Rosane Moura Aguiar, Milena Mascarenhas Ferraz, Silvana Batista Gaino, Francisco Capani and George E Barreto (2019) Mitochondrial KATP Channel and Dopaminergic Vulnerability Neurons in Parkinson's Disease. Croatia : IntechOpen Parkinson's Disease and Beyond - A Neurocognitive Approach
Read moreNeuroprotection with estradiol in experimental perinatal asphyxia: a new approach
George Barreto, Ezequiel Saraceno, Janneth González, Rodolfo Kolliker, Rocío Castilla, Francisco Capani (2014) Neuroprotection with estradiol in experimental perinatal asphyxia: a new approach. Ireland : Elsevier Estrogen Effects on Traumatic Brain Injury
Read moreNeuroprotection by exogenous estrogenic compounds following traumatic brain injury
Ana Belen Lopez-Rodriguez, Marco Ávila-Rodriguez, Nelson E Vega-Vela, Francisco Capani, Janneth Gonzalez, Luis Miguel García-Segura, George E. Barreto (2014) Neuroprotection by exogenous estrogenic compounds following traumatic brain injury. Ireland : Elsevier Estrogen Effects on Traumatic Brain Injury
Read moreNatural antioxidants in dementia: an overview
Ricardo Cabezas, Marco Fidel Avila, Daniel Torrente, Janneth Gonzalez, Ramon Santos El-Bacha, Rubem Guedes, George E. Barreto (2014) Natural antioxidants in dementia: an overview. Ireland : Academic Press (Elsevier) Diet and Nutrition in Dementia and cognitive decline series book
Read moreAnalysis of Binding Residues between PDGF-BB and Epidermal Growth Factor Receptor: A Computational Docking Study
Ricardo Cabezas, Daniel Torrente, Marcos Avila, Janneth Gonzalez, George E. Barreto (2013) Analysis of Binding Residues between PDGF-BB and Epidermal Growth Factor Receptor: A Computational Docking Study. Colombia : Springer 2nd Congress on Computational Biology and Bioinformatics
Read moreStructural and functional prediction of the hypothetical protein PA2481
David Diaz, George E. Barreto, Janneth González (2013) Structural and functional prediction of the hypothetical protein PA2481. Colombia : Springer 2nd Congress on Computational Biology and Bioinformatics
Read moreRole of astrocytes in Parkinson: A double edged-sword
Ricardo Cabezas, Marco Fidel, Ramon El-Bachá, Janneth Gonzalez, Ludis Morales, George E. Barreto (2013) Role of astrocytes in Parkinson: A double edged-sword. Croatia : Intech Neurodegenerative Diseases
Read moreIn silico Analysis of Iduronate 2 Sulfatase Mutations in Colombian Patients with Hunter Syndrome
Johanna Galvis, Janneth González, Daniel Torrente, Harvy Velasco, George E. Barreto (2013) In silico Analysis of Iduronate 2 Sulfatase Mutations in Colombian Patients with Hunter Syndrome. Colombia : Springer 2nd Congress on Computational Biology and Bioinformatics
Read moreRole of astrocytes in Neurodegenerative diseases
George E. Barreto, Janneth González, Francisco Capani, Ludis Morales (2011) Role of astrocytes in Neurodegenerative diseases. Croatia : InTech Neurodegenerative Diseases
Read moreEdited Books
Editorial on Cerebral endothelial and glial cells are more than bricks in the Great Wall of the brain: insights into the way the blood-brain barrier actually works (celebrating the centenary of Goldman's experiments).
(2015) Editorial on Cerebral endothelial and glial cells are more than bricks in the Great Wall of the brain: insights into the way the blood-brain barrier actually works (celebrating the centenary of Goldman's experiments).. Lausanne : Frontiers in Cellular Neuroscience
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