Dr. George Barreto
Biography
Dr. Barreto earned his PhD in Neuroscience (2009) from the Universidad Complutense Madrid (Spain) studying the effects of neurosteroids on reactive glia with traumatic brain injury under the supervision of Professor Luis Miguel Garcia-Segura. His Post-doctoral training in Neuroscience at Stanford University School of Medicine (2009-2011), under the mentorship of Professor Rona G. Giffard, focused on addressing the role of astrocytes activation following stroke and enhance astrocytic functions targeting neuronal protection. With the collaboration of Professor Carla J. Shatz, also from Stanford, Dr Barreto and cols discovered that both PirB receptor and MHCI molecules are involved in the physiopathology of stroke by regulating astroglia activation and behavioural outcome. Nowadays he is a Lecturer in Cell Biology/Immunology in the Department of Biological Sciences at the University of Limerick (Ireland), is a member of the Bernal Institute and Health Research Institute from the same University.Associate Editor, Frontiers in Aging Neuroscience
Associate Editor, Frontiers in Neurology/Neurotrauma
Associate Editor, Frontiers in Neuroscience
Associate Editor, Frontiers in Nutrition
Associate Editor, Nutritional Neuroscience
Academic Editor, Plos One
Associate Editor, BMC Neurology
Consulting Editor, Pharmacological Research
Current Students
2019 Oscar Hidalgo Lanussa. Ph.D. in Biological Sciences
2019 Angie Garzón. M.Sc in Neurosciences
Students supervised
2019 Yeimy González. Ph.D. in Biological Sciences
2018 Eliana Báez. Ph.D. in Biological Sciences
2017 Ricardo Cabezas. Ph.D. in Biological Sciences
2016 Marco Ávila-Rodriguez. Ph.D. in Biological Sciences
2016 Oscar Hidalgo Lanussa. M.Sc in Biological Sciences
2016 Natalia Areiza. M.Sc in Nutrition Sciences
Research Interests
We are keen to understand how androgens and estrogens affect brain functions, particularly on how these hormones control mitochondrial functions in the healthy and diseased brain with life span in a sex dimorphic manner. We are currently investigating these research areas:- The effects of synthetic hormones (e.g. tibolone) on mitochondria metabolism.
- Hormonal signaling affecting cellular outcome, and how important this is for mitochondrial respiration under neurological diseases in presence or absence of hormones.
- Dysregulation of lipid metabolism within mitochondria and neuroimmune response following brain damage.
- Drug design and development of new drugs analogues to hormones for targeting mitochondria
Research Areas:
Neuroendocrinology
Neurobiology
Neurosciences
Key Terms:
Mitochondria
Biological Sex differences
Brain
Glial Cells
Neurosteroids
Neurodegenerative Diseases
Hormones
Neuroinflammation
Traumatic brain injury
Professional Activities
Committee
- 2019 Grants Reviewer (Expert). National Science Centre Poland, Poland,
- 2019 Grants Reviewer (Expert). Ministery of Science, Technology and Innovation (Foncyt), Programme PICT, Argentina,
- 2019 Evaluation Committee (Expert). H2020-MSCA-IF-2019, European Commission,
- 2018 Evaluation Committee. MFP-COFUND PhD fellowships, Universitat Rovira i Virgili, Tarragona, Spain,
- 2018 Grant Review. National Research Council (Colciencias),
- 2018 Evaluation Committee. Postdoctoral Fellowship Program. National Research Council (Colciencias),
- 2018 Evaluation Committee (Expert). H2020-MSCA-IF-2018, European Commission,
- 2017 Grant Review. Career Development Award, Human Frontier Science Program (HFSP), France,
- 2017 Evaluation Committee. Postdoctoral Fellowship Program. National Research Council (Colciencias),
- 2017 Book proposal reviewer. Title: Neuroprotection in Autism, Schizophrenia & Alzheimer's Disease,
- 2016 Grant Review. National Research Council (Colciencias),
- 2015 Grant Review. National Research Council (Colciencias),
- 2014 Ad-Hoc and Evaluation Committee. Grants Program,
- 2014 Evaluation Committee Grant Review. Parkinson UK,
- 2014 Grant Review. National Research Council (Colciencias),
Employment
- 2009 Stanford University School of Medicine - Post-Doctoral Fellow in Neurosciences
Award
- 2009 - Postdoctoral Fellowship
- 2005 - WERC/FENS PhD Fellowship
Education
- 2009 Complutense University Madrid - PhD in Biological Sciences
Language
- Portuguese
- Spanish
Association
- Member, International Brain Research Organization
- Full member, International Society for Neurochemistry
- Full member, Federation of European Neuroscience Societies
- Full member, European Society of Neurochemistry
Research Collaborators
- Luis Miguel Garcia- Segura - International Collaboration Type -Spain -Cajal Institute, Madrid, Spain
- Roberto C. Melcangi - International Collaboration Type - University of Milan -Italy
- Valentina Echeverria - Joint Publication -Chile -Universidad San Sebastián
- Janneth González - Joint Publication
Peer Reviewed Journals
Dissecting Sex-Related Cognition between Alzheimer's Disease and Diabetes: From Molecular Mechanisms to Potential Therapeutic Strategies.
Ashraf GM;Ebada MA;Suhail M;Ali A;Uddin MS;Bilgrami AL;Perveen A;Husain A;Tarique M;Hafeez A;Alexiou A;Ahmad A;Kumar R;Banu N;Najda A;Sayed AA;Albadrani GM;Abdel-Daim MM;Peluso I;Barreto GE; (2021) Dissecting Sex-Related Cognition between Alzheimer's Disease and Diabetes: From Molecular Mechanisms to Potential Therapeutic Strategies.. Oxidative Medicine And Cellular Longevity
Common genes and pathways involved in the response to stressful stimuli by astrocytes: A meta-analysis of genome-wide expression studies.
González-Giraldo Y;Forero DA;Barreto GE;Aristizábal-Pachón A; (2021) Common genes and pathways involved in the response to stressful stimuli by astrocytes: A meta-analysis of genome-wide expression studies.. Genomics
Identification of new BACE1 inhibitors for treating Alzheimer's disease.
Kushwaha P;Singh V;Somvanshi P;Bhardwaj T;Barreto GE;Ashraf GM;Mishra BN;Chundawat RS;Haque S; (2021) Identification of new BACE1 inhibitors for treating Alzheimer's disease.. Journal of molecular modeling
Therapeutic potential of trehalose in neurodegenerative diseases: the knowns and unknowns.
Khalifeh M;Barreto GE;Sahebkar A; (2021) Therapeutic potential of trehalose in neurodegenerative diseases: the knowns and unknowns.. Neural Regeneration Research
Brain lipidomics as a rising field in neurodegenerative contexts: Perspectives with Machine Learning approaches.
Castellanos DB;Martín-Jiménez CA;Rojas-Rodríguez F;Barreto GE;González J; (2021) Brain lipidomics as a rising field in neurodegenerative contexts: Perspectives with Machine Learning approaches.. Frontiers In Neuroendocrinology
Biomolecular alterations in acute traumatic brain injury (TBI) using Fourier transform infrared (FTIR) imaging spectroscopy.
Rakib F;Al-Saad K;Ahmed T;Ullah E;Barreto GE;Md Ashraf G;Ali MHM; (2021) Biomolecular alterations in acute traumatic brain injury (TBI) using Fourier transform infrared (FTIR) imaging spectroscopy.. Spectrochimica Acta Part A-Molecular And Biomolecular Spectroscopy
Astrocytes and Inflammasome: A Possible Crosstalk in Neurological Diseases.
Nourbakhsh F;Read MI;Barreto GE;Sahebkar A; (2021) Astrocytes and Inflammasome: A Possible Crosstalk in Neurological Diseases.. Current medicinal chemistry
Apoptotic neurons and amyloid-beta clearance by phagocytosis in Alzheimer's disease: Pathological mechanisms and therapeutic outlooks.
Tajbakhsh A;Read M;Barreto GE;Ávila-Rodriguez M;Gheibi-Hayat SM;Sahebkar A; (2021) Apoptotic neurons and amyloid-beta clearance by phagocytosis in Alzheimer's disease: Pathological mechanisms and therapeutic outlooks.. European Journal Of Pharmacology
Neural Stem Cell-Based Therapies and Glioblastoma Management: Current Evidence and Clinical Challenges.
Benmelouka AY;Munir M;Sayed A;Attia MS;Ali MM;Negida A;Alghamdi BS;Kamal MA;Barreto GE;Ashraf GM;Meshref M;Bahbah EI; (2021) Neural Stem Cell-Based Therapies and Glioblastoma Management: Current Evidence and Clinical Challenges.. International Journal Of Molecular Sciences
Vitamin D Receptor Genetic Polymorphisms and the Risk of Multiple Sclerosis: A Systematic Review and Meta-Analysis
Mohammadi A, Azarnezhad A, Khanbabaei H, Izadpanah E, Abdollahzadeh R, Barreto GE, Sahebkar A (2020) Vitamin D Receptor Genetic Polymorphisms and the Risk of Multiple Sclerosis: A Systematic Review and Meta-Analysis. Steroids
Nano-engineered nerolidol loaded lipid carrier delivery system attenuates cyclophosphamide neurotoxicity - Probable role of NLRP3 inflammasome and caspase-1.
Iqubal A;Syed MA;Najmi AK;Azam F;Barreto GE;Iqubal MK;Ali J;Haque SE; (2020) Nano-engineered nerolidol loaded lipid carrier delivery system attenuates cyclophosphamide neurotoxicity - Probable role of NLRP3 inflammasome and caspase-1.. Experimental Neurology
Emerging Therapeutic Promise of Ketogenic Diet to Attenuate Neuropathological Alterations in Alzheimer's Disease.
Uddin MS;Kabir MT;Tewari D;Al Mamun A;Barreto GE;Bungau SG;Bin-Jumah MN;Abdel-Daim MM;Ashraf GM; (2020) Emerging Therapeutic Promise of Ketogenic Diet to Attenuate Neuropathological Alterations in Alzheimer's Disease.. Molecular Neurobiology
Neuroprotection by curcumin: A review on brain delivery strategies.
Askarizadeh A;Barreto GE;Henney NC;Majeed M;Sahebkar A; (2020) Neuroprotection by curcumin: A review on brain delivery strategies.. International journal of pharmaceutics
Cotinine Enhances Fear Extinction and Astrocyte Survival by Mechanisms Involving the Nicotinic Acetylcholine Receptors Signaling
Oliveros-Matus P, Perez-Urrutia N, Alvarez-Ricartes N, Echeverria F, Barreto GE, Elliott J, Iarkov A, Echeverria V (2020) Cotinine Enhances Fear Extinction and Astrocyte Survival by Mechanisms Involving the Nicotinic Acetylcholine Receptors Signaling. Frontiers In Pharmacology
Estrogen Signaling in Alzheimer's Disease: Molecular Insights and Therapeutic Targets for Alzheimer's Dementia
Uddin MS, Rahman MM, Jakaria M, Rahman MS, Hossain MS, Islam A, Ahmed M, Mathew B, Omar UM, Barreto GE, Ashraf GM (2020) Estrogen Signaling in Alzheimer's Disease: Molecular Insights and Therapeutic Targets for Alzheimer's Dementia. Molecular Neurobiology
Molecular Mechanisms of ER Stress and UPR in the Pathogenesis of Alzheimer's Disease
Uddin MS, Tewari D, Sharma G, Kabir MT, Barreto GE, Bin-Jumah MN, Perveen A, Abdel-Daim MM, Ashraf GM (2020) Molecular Mechanisms of ER Stress and UPR in the Pathogenesis of Alzheimer's Disease. Molecular Neurobiology
Advances in Astrocyte Computational Models: From Metabolic Reconstructions to Multi-omic Approaches.
González J;Pinzón A;Angarita-Rodríguez A;Aristizabal AF;Barreto GE;Martín-Jiménez C; (2020) Advances in Astrocyte Computational Models: From Metabolic Reconstructions to Multi-omic Approaches.. Frontiers In Neuroinformatics
The potential of mitochondrial modulation by neuroglobin in treatment of neurological disorders.
Gorabi AM;Aslani S;Barreto GE;Báez-Jurado E;Kiaie N;Jamialahmadi T;Sahebkar A; (2020) The potential of mitochondrial modulation by neuroglobin in treatment of neurological disorders.. Free Radical Biology And Medicine
The neutrophil-to-lymphocyte ratio in Alzheimer's disease: Current understanding and potential applications.
Sayed A;Bahbah EI;Kamel S;Barreto GE;Ashraf GM;Elfil M; (2020) The neutrophil-to-lymphocyte ratio in Alzheimer's disease: Current understanding and potential applications.. Journal Of Neuroimmunology
The Role of Nuclear Factors as "Find-Me"/alarmin Signals and Immunostimulation in Defective Efferocytosis and Related Disorders
Tajbakhsh A, Rezaee M, Barreto GE, Moallem SA, Henney NC, Sahebkar A (2020) The Role of Nuclear Factors as "Find-Me"/alarmin Signals and Immunostimulation in Defective Efferocytosis and Related Disorders. International Immunopharmacology
Exploring the Potential of Neuroproteomics in Alzheimer's Disease.
Uddin MS;Kabir MT;Jakaria M;Sobarzo-Sánchez E;Barreto GE;Perveen A;Hafeez A;Bin-Jumah MN;Abdel-Daim MM;Ashraf GM; (2020) Exploring the Potential of Neuroproteomics in Alzheimer's Disease.. Current Topics In Medicinal Chemistry
Strategies for the Treatment of Parkinson's Disease: Beyond Dopamine
Iarkov A, Barreto GE, Grizzell JA, Echeverria V (2020) Strategies for the Treatment of Parkinson's Disease: Beyond Dopamine. Frontiers In Aging Neuroscience
Pharmacological approaches to mitigate neuroinflammation in Alzheimer's disease
Uddin MS, Kabir MT, Mamun AA, Barreto GE, Rashid M, Perveen A, Ashraf GM (2020) Pharmacological approaches to mitigate neuroinflammation in Alzheimer's disease. International Immunopharmacology
Boosting the autophagy-lysosomal pathway by phytochemicals: A potential therapeutic strategy against Alzheimer's disease.
Nourbakhsh F;Read MI;Barreto GE;Sahebkar A; (2020) Boosting the autophagy-lysosomal pathway by phytochemicals: A potential therapeutic strategy against Alzheimer's disease.. Iubmb Life
Tibolone Ameliorates the Lipotoxic Effect of Palmitic Acid in Normal Human Astrocytes
Martin-Jiménez C.;González J.;Vesga D.;Aristizabal A.;Barreto G.E. (2020) Tibolone Ameliorates the Lipotoxic Effect of Palmitic Acid in Normal Human Astrocytes. Neurotoxicity Research
Revisiting the role of brain and peripheral Aβ in the pathogenesis of Alzheimer's disease
Uddin MS, Kabir MT, Tewari D, Mamun AA, Mathew B, Aleya L, Barreto GE, Bin-Jumah MN, Abdel-Daim MM, Ashraf GM (2020) Revisiting the role of brain and peripheral Aβ in the pathogenesis of Alzheimer's disease. Journal Of The Neurological Sciences
Tibolone as Hormonal Therapy and Neuroprotective Agent
Del Río JP, Molina S, Hidalgo-Lanussa O, Garcia-Segura LM, Barreto GE (2020) Tibolone as Hormonal Therapy and Neuroprotective Agent. Trends In Endocrinology And Metabolism
Multifarious roles of mTOR signaling in cognitive aging and cerebrovascular dysfunction of Alzheimer's disease.
Uddin MS;Rahman MA;Kabir MT;Behl T;Mathew B;Perveen A;Barreto GE;Bin-Jumah MN;Abdel-Daim MM;Ashraf GM; (2020) Multifarious roles of mTOR signaling in cognitive aging and cerebrovascular dysfunction of Alzheimer's disease.. Iubmb Life
Multiple Pathways Involved in Palmitic Acid-Induced Toxicity: A System Biology Approach
Osorio D, Pinzón A, Martín-Jiménez C, Barreto GE, González J (2020) Multiple Pathways Involved in Palmitic Acid-Induced Toxicity: A System Biology Approach. Frontiers In Neuroscience
Circadian and Sleep Dysfunction in Alzheimer's Disease
Uddin MS, Tewari D, Mamun AA, Kabir MT, Niaz K, Wahed MII, Barreto GE, Ashraf GM (2020) Circadian and Sleep Dysfunction in Alzheimer's Disease. Ageing Research Reviews
Anti-Androgen Drugs in the Treatment of Obsessive-Compulsive Disorder: A Systematic Review
Homa Nomani;Amir Hooshang Mohammadpour;Seyed Mohammad Hassan Moallem;Mahdi Jannati YazdanAbad;George E. Barreto;Amirhossein Sahebkar; (2020) Anti-Androgen Drugs in the Treatment of Obsessive-Compulsive Disorder: A Systematic Review. Current medicinal chemistry
Raloxifene Potentiates The Effect Of Fluoxetine Against Maximal Electroshock Induced Seizures In Mice
ttoo FH, Tabassum N, Javed MN, Nigar S, Sharma S, Barkat MA, Harshita, Alam MS, Ansari MA, Barreto GE, Ashraf GM (2020) Raloxifene Potentiates The Effect Of Fluoxetine Against Maximal Electroshock Induced Seizures In Mice. European Journal Of Pharmaceutical Sciences
Effects of curcumin on neurological diseases: focus on astrocytes.
Eghbaliferiz S;Farhadi F;Barreto GE;Majeed M;Sahebkar A; (2020) Effects of curcumin on neurological diseases: focus on astrocytes.. Pharmacological Reports
Resolution of Inflammation in Neurodegenerative Diseases: The Role of Resolvins
Chamani S, Bianconi V, Tasbandi A, Pirro M, Barreto GE, Jamialahmadi T, Sahebkar A (2020) Resolution of Inflammation in Neurodegenerative Diseases: The Role of Resolvins. Mediators Of Inflammation
Recent advancements in liposome-based strategies for effective drug delivery to the brain.
Zaman P;Penson PE;Barreto GE;Sahebkar A; (2020) Recent advancements in liposome-based strategies for effective drug delivery to the brain.. Current medicinal chemistry
Curcumin: a phytochemical modulator of estrogens and androgens in tumors of the reproductive system
Mohajeri M, Bianconi V, Ávila-Rodriguez MF, Barreto GE, Jamialahmadi T, Pirro M, Sahebkar (2020) Curcumin: a phytochemical modulator of estrogens and androgens in tumors of the reproductive system. Pharmacological Research
Developmental lead (Pb)-induced deficits in redox and bioenergetic status of cerebellar synapses are ameliorated by ascorbate supplementation
Ahmad F.;Haque S.;Ravinayagam V.;Ahmad A.;Kamli M.R.;Barreto G.E.;Ghulam Md Ashraf (2020) Developmental lead (Pb)-induced deficits in redox and bioenergetic status of cerebellar synapses are ameliorated by ascorbate supplementation. Toxicology
Bioinformatic Study of Involved Mechanisms in Relapse and Drug Resistance of Tamoxifen-Treated Breast Cancer.
Keikha M;Barreto GE;González J;Sahebkar A; (2020) Bioinformatic Study of Involved Mechanisms in Relapse and Drug Resistance of Tamoxifen-Treated Breast Cancer.. Anti-Cancer Agents In Medicinal Chemistry
Trehalose against Alzheimer's Disease: Insights into a Potential Therapy
Khalifeh M, Read MI, Barreto GE, Sahebkar A (2020) Trehalose against Alzheimer's Disease: Insights into a Potential Therapy. Bioessays
Lipid-based nanoformulations in the treatment of neurological disorders
Pottoo FH, Sharma S, Javed MN, Barkat MA, Harshita, Alam MS, Naim MJ, Alam O, Ansari MA, Barreto GE, Ashraf GM (2020) Lipid-based nanoformulations in the treatment of neurological disorders. Drug Metabolism Reviews
Epigenetic Aspects of Multiple Sclerosis and Future Therapeutic Options
Jamebozorgi K, Rostami D, Pormasoumi H, Taghizadeh E, Barreto GE, Sahebkar A (2020) Epigenetic Aspects of Multiple Sclerosis and Future Therapeutic Options. International Journal Of Neuroscience
Antitumor effects of curcumin: A lipid perspective
Mehri Bemani Naeini;Amir Abbas Momtazi;Mahmoud Reza Jaafari;Thomas P. Johnston;George Barreto;Maciej Banach;Amirhossein Sahebkar; (2019) Antitumor effects of curcumin: A lipid perspective. Journal Of Cellular Physiology
Scientific Productivity in Neurosciences in Latin America: A Scientometrics Perspective
Forero DA, Trujillo ML, González-Giraldo Y, Barreto GE (2019) Scientific Productivity in Neurosciences in Latin America: A Scientometrics Perspective. International Journal Of Neuroscience
The effects of statins on microglial cells to protect against neurodegenerative disorders: A mechanistic review
Bagheri H, Ghasemi F, Barreto GE, Sathyapalan T, Jamialahmadi T, Sahebkar A (2019) The effects of statins on microglial cells to protect against neurodegenerative disorders: A mechanistic review. Biofactors
PCSK9 and inflammation: a review of experimental and clinical evidence
Momtazi-Borojeni AA, Sabouri-Rad S, Gotto AM, Pirro M, Banach M, Awan Z, Barreto GE, Sahebkar A (2019) PCSK9 and inflammation: a review of experimental and clinical evidence. European Heart Journal
Antidiabetic potential of saffron and its active constituents
Yaribeygi, H.,Zare, V.,Butler, A. E.,Barreto, G. E.,Sahebkar, A. (2019) Antidiabetic potential of saffron and its active constituents. Journal Of Cellular Physiology :8610-8617
Higher zinc concentrations in hair of Parkinson's disease are associated with psychotic complications and depression
Dos Santos AB, Bezerra MA, Rocha ME, Barreto GE, Kohlmeier KA (2019) Higher zinc concentrations in hair of Parkinson's disease are associated with psychotic complications and depression. Journal Of Neural Transmission
Efficacy of curcumin on prevention of drugâinduced nephrotoxicity: A review of animal studies
Javad Motaharinia;Yunes Panahi;George E. Barreto;Fatemeh Beiraghdar;Amirhossein Sahebkar; (2019) Efficacy of curcumin on prevention of drugâinduced nephrotoxicity: A review of animal studies. Biofactors
Metabolic effects of antidiabetic drugs on adipocytes and adipokine expression
Yaribeygi, H.,Simental-Mendia, L. E.,Barreto, G. E.,Sahebkar, A. (2019) Metabolic effects of antidiabetic drugs on adipocytes and adipokine expression. Journal Of Cellular Physiology
Astrocytes Mediate Protective Actions of Estrogenic Compounds after Traumatic Brain Injury
Martin-Jimenez, C.,Gaitan-Vaca, D. M.,Areiza, N.,Echeverria, V.,Ashraf, G. M.,Gonzalez, J.,Sahebkar, A.,Garcia-Segura, L. M.,Barreto, G. E. (2019) Astrocytes Mediate Protective Actions of Estrogenic Compounds after Traumatic Brain Injury. Neuroendocrinology :142-160
qPCR-based methods for expression analysis of miRNAs
Forero DA, González-Giraldo Y, Castro-Vega LJ, Barreto GE (2019) qPCR-based methods for expression analysis of miRNAs. Biotechniques
Tibolone attenuates inflammatory response by palmitic acid and preserves mitochondrial membrane potential in astrocytic cells through estrogen receptor beta
Gonzalez-Giraldo, Y.,Forero, D. A.,Echeverria, V.,Garcia-Segura, L. M.,Barreto, G. E. (2019) Tibolone attenuates inflammatory response by palmitic acid and preserves mitochondrial membrane potential in astrocytic cells through estrogen receptor beta. Molecular And Cellular Endocrinology :65-78
Molecular cloning, expression, purification, and functional characterization of SPâ22 gene from Bombyx mori
Elshareef Salah Eldein;Mohnad Abdalla;Wafa Ali Eltayb;Amr Ahmed ElâArabey;Magdah Ganash;Fawaz D. Alshammari;George Barreto;Ghulam Md Ashraf; (2019) Molecular cloning, expression, purification, and functional characterization of SPâ22 gene from Bombyx mori. Journal Of Cellular Biochemistry
Modulatory effects of curcumin on heat shock proteins in cancer: A promising therapeutic approach
Fatemeh Forouzanfar;George Barreto;Muhammed Majeed;Amirhossein Sahebkar; (2019) Modulatory effects of curcumin on heat shock proteins in cancer: A promising therapeutic approach. Biofactors
Antioxidative potential of antidiabetic agents: A possible protective mechanism against vascular complications in diabetic patients
Yaribeygi, H.,Butler, A. E.,Barreto, G. E.,Sahebkar, A. (2019) Antioxidative potential of antidiabetic agents: A possible protective mechanism against vascular complications in diabetic patients. Journal Of Cellular Physiology :2436-2446
Neuroprotective effects of minocycline on focal cerebral ischemia injury: a systematic review.
Naderi Y, Panahi Y, Barreto GE, Sahebkar A (2019) Neuroprotective effects of minocycline on focal cerebral ischemia injury: a systematic review.. Neural Regeneration Research
The Therapeutic Potential of Mesenchymal Stem Cell-Derived Exosomes in Treatment of Neurodegenerative Diseases
Gorabi AM, Kiaie N, Barreto GE, Read MI, Tafti HA, Sahebkar A (2019) The Therapeutic Potential of Mesenchymal Stem Cell-Derived Exosomes in Treatment of Neurodegenerative Diseases. Molecular Neurobiology
Beneficial effects of nâhexane bark extract of Onosma echioides L. on diabetic peripheral neuropathy
Ambreen Shoaib;Badruddeen;Rakesh Kumar Dixit;Magdah Ganash;George Barreto;Ghulam Md Ashraf;Hefazat Hussain Siddiqui; (2019) Beneficial effects of nâhexane bark extract of Onosma echioides L. on diabetic peripheral neuropathy. Journal Of Cellular Biochemistry
Effects of curcumin on mitochondria in neurodegenerative diseases
Bagheri H, Ghasemi F, Barreto GE, Rafiee R, Sathyapalan T, Sahebkar A. (2019) Effects of curcumin on mitochondria in neurodegenerative diseases. Biofactors
Effects of Curcumin on Microglial Cells
Faezeh Ghasemi;Hossein Bagheri;George E. Barreto;Morgayn I. Read;Amirhossein Sahebkar; (2019) Effects of Curcumin on Microglial Cells. Neurotoxicity Research
Effects of estrogens and androgens on mitochondria under normal and pathological conditions
Mohajeri, M.,Martin-Jimenez, C.,Barreto, G. E.,Sahebkar, A. (2019) Effects of estrogens and androgens on mitochondria under normal and pathological conditions. Progress In Neurobiology
Anti-inflammatory effects of resolvins in diabetic nephropathy: Mechanistic pathways
Yaribeygi, H.,Atkin, S. L.,Simental-Mendia, L. E.,Barreto, G. E.,Sahebkar, A. (2019) Anti-inflammatory effects of resolvins in diabetic nephropathy: Mechanistic pathways. Journal Of Cellular Physiology
Novel computational deep learning strategy for neuroprotection identification reveals unique set of nicotine analogs as potential therapeutic compounds against Parkinsonâs disease
Felipe Rojas-RodrÃguez;Carlos Morantes;Andrés Pinzón;George E. Barreto;Ricardo Cabezas;Leonardo Mariño;Janneth González; (2019) Novel computational deep learning strategy for neuroprotection identification reveals unique set of nicotine analogs as potential therapeutic compounds against Parkinsonâs disease.
Melatonin in Alzheimer's Disease: A Latent Endogenous Regulator of Neurogenesis to Mitigate Alzheimer's Neuropathology
Hossain MF, Uddin MS, Uddin GMS, Sumsuzzman DM, Islam MS, Barreto GE, Mathew B, Ashraf GM (2019) Melatonin in Alzheimer's Disease: A Latent Endogenous Regulator of Neurogenesis to Mitigate Alzheimer's Neuropathology. Molecular Neurobiology
In silico evidence of direct interaction between statins and beta-amyloid
Shakour, N.,Bianconi, V.,Pirro, M.,Barreto, G. E.,Hadizadeh, F.,Sahebkar, A. (2019) In silico evidence of direct interaction between statins and beta-amyloid. Journal Of Cellular Biochemistry :4710-4715
A review of the pharmacological and therapeutic effects of auraptene.
Bibak B, Shakeri F, Barreto GE, Keshavarzi Z, Sathyapalan T, Sahebkar A. (2019) A review of the pharmacological and therapeutic effects of auraptene.. Biofactors
Molecular mechanisms and cellular events involved in the neuroprotective actions of estradiol. Analysis of sex differences
Azcoitia I, Barreto GE, Garcia-Segura LM (2019) Molecular mechanisms and cellular events involved in the neuroprotective actions of estradiol. Analysis of sex differences. Frontiers In Neuroendocrinology
Impact of sex differences and gender specificity on behavioral characteristics and pathophysiology of neurodegenerative disorders.
Ullah MF, Ahmad A, Bhat SH, Abu-Duhier FM, Barreto GE, Ashraf GM (2019) Impact of sex differences and gender specificity on behavioral characteristics and pathophysiology of neurodegenerative disorders.. Neuroscience And Biobehavioral Reviews :95-105
Protein modeling, molecular network and molecular dynamics study of newly sequenced interleukin-18 (IL-18) gene in Mus musculus
Yadav, B. S.,Chaturvedi, N.,Yadav, P. K.,Marina, N.,Ganash, M.,Barreto, G. E.,Ashraf, G. M.,Ahmad, K.,Baig, M. H. (2019) Protein modeling, molecular network and molecular dynamics study of newly sequenced interleukin-18 (IL-18) gene in Mus musculus. Journal Of Cellular Physiology
The Synergistic Effect of Raloxifene, Fluoxetine, and Bromocriptine Protects Against Pilocarpine-Induced Status Epilepticus and Temporal Lobe Epilepsy
Pottoo, F. H.,Tabassum, N.,Javed, M. N.,Nigar, S.,Rasheed, R.,Khan, A.,Barkat, M. A.,Alam, M. S.,Maqbool, A.,Ansari, M. A.,Barreto, G. E.,Ashraf, G. M. (2019) The Synergistic Effect of Raloxifene, Fluoxetine, and Bromocriptine Protects Against Pilocarpine-Induced Status Epilepticus and Temporal Lobe Epilepsy. Molecular Neurobiology :1233-1247
Emerging roles for high-density lipoproteins in neurodegenerative disorders
Bahrami A, Barreto GE, Lombardi G, Pirro M, Sahebkar A (2019) Emerging roles for high-density lipoproteins in neurodegenerative disorders. Biofactors
Molecular mechanisms involved in the protective actions of Selective Estrogen Receptor Modulators in brain cells
Baez-Jurado, E.,Rincon-Benavides, M. A.,Hidalgo-Lanussa, O.,Guio-Vega, G.,Ashraf, G. M.,Sahebkar, A.,Echeverria, V.,Garcia-Segura, L. M.,Barreto, G. E. (2019) Molecular mechanisms involved in the protective actions of Selective Estrogen Receptor Modulators in brain cells. Frontiers In Neuroendocrinology :44-64
Endothelial PPARγ Is Crucial for Averting Age-Related Vascular Dysfunction by Stalling Oxidative Stress and ROCK.
Uddin MS, Kabir MT, Jakaria M, Mamun AA, Niaz K, Amran MS, Barreto GE, Ashraf GM. (2019) Endothelial PPARγ Is Crucial for Averting Age-Related Vascular Dysfunction by Stalling Oxidative Stress and ROCK.. Neurotoxicity Research
Autophagic dysfunction in Alzheimer's disease: Cellular and molecular mechanistic approaches to halt Alzheimer's pathogenesis
Uddin, M. S.,Mamun, A. A.,Labu, Z. K.,Hidalgo-Lanussa, O.,Barreto, G. E.,Ashraf, G. M. (2019) Autophagic dysfunction in Alzheimer's disease: Cellular and molecular mechanistic approaches to halt Alzheimer's pathogenesis. Journal Of Cellular Physiology :8094-8112
Raloxifene attenuates oxidative stress and preserves mitochondrial function in astrocytic cells upon glucose deprivation
Vesga-Jimenez, D. J.,Hidalgo-Lanussa, O.,Baez-Jurado, E.,Echeverria, V.,Ashraf, G. M.,Sahebkar, A.,Barreto, G. E. (2019) Raloxifene attenuates oxidative stress and preserves mitochondrial function in astrocytic cells upon glucose deprivation. J Cell Physiolj Cell Physiol :2051-2057
Neuroprotective Effects of Curcumin Through Autophagy Modulation
Forouzanfar F, Read MI, Barreto GE, Sahebkar A (2019) Neuroprotective Effects of Curcumin Through Autophagy Modulation. Iubmb Life
(E)-Nicotinaldehyde O-Cinnamyloxime, a Nicotine Analog, Attenuates Neuronal Cells Death Against Rotenone-Induced Neurotoxicity
Jurado-Coronel, J. C.,Loaiza, A. E.,Diaz, J. E.,Cabezas, R.,Ashraf, G. M.,Sahebkar, A.,Echeverria, V.,Gonzalez, J.,Barreto, G. E. (2019) (E)-Nicotinaldehyde O-Cinnamyloxime, a Nicotine Analog, Attenuates Neuronal Cells Death Against Rotenone-Induced Neurotoxicity. Molecular Neurobiology :1221-1232
Trehalose as a promising therapeutic candidate for the treatment of Parkinson's disease
Khalifeh, M.,Barreto, G. E.,Sahebkar, A. (2019) Trehalose as a promising therapeutic candidate for the treatment of Parkinson's disease. British Journal Of Pharmacology
Medicinal plants in traumatic brain injury: Neuroprotective mechanisms revisited
Keshavarzi Z, Shakeri F, Barreto GE, Bibak B, Sathyapalan T, Sahebkar A (2019) Medicinal plants in traumatic brain injury: Neuroprotective mechanisms revisited. Biofactors
Lipotoxicity, neuroinflammation, glial cells and estrogenic compounds
Hidalgo-Lanussa O, Baez-Jurado E, Echeverria V, Ashraf GM, Sahebkar A, Garcia-Segura LM, Melcangi RC, Barreto GE (2019) Lipotoxicity, neuroinflammation, glial cells and estrogenic compounds. Journal Of Neuroendocrinology
Prevalence, pathological mechanisms, and genetic basis of limb-girdle muscular dystrophies: A review
Taghizadeh, E.,Rezaee, M.,Barreto, G. E.,Sahebkar, A. (2019) Prevalence, pathological mechanisms, and genetic basis of limb-girdle muscular dystrophies: A review. Journal Of Cellular Physiology :7874-7884
Neuroprotective effects of curcumin through autophagy modulation
Forouzanfar F, Read MI, Barreto GE, Sahebkar A (2019) Neuroprotective effects of curcumin through autophagy modulation. Iubmb Life
Protective Effects of Curcumin Against Ischemia-Reperfusion Injury in the Nervous System
Bavarsad, K.,Barreto, G. E.,Hadjzadeh, M. A.,Sahebkar, A. (2019) Protective Effects of Curcumin Against Ischemia-Reperfusion Injury in the Nervous System. Molecular Neurobiology :1391-1404
Copper and Neurotoxicity in Autism Spectrum Disorder
Santos G, Borges JMP, Avila-Rodriguez M, Gaíno SB, Barreto GE, Rúbio EP, Aguiar RM, Galembeck E, Bromochenkel CB, de Oliveira DM. (2019) Copper and Neurotoxicity in Autism Spectrum Disorder. Current Pharmaceutical Design
TERT inhibition leads to reduction of IL6 expression induced by palmitic acid and interferes with the protective effects of tibolone in an astrocytic cell model.
Gonzalez-Giraldo Y, Garzón-Benitez AV, Forero DA, Barreto GE (2019) TERT inhibition leads to reduction of IL6 expression induced by palmitic acid and interferes with the protective effects of tibolone in an astrocytic cell model.. Journal Of Neuroendocrinology
Chitosan-based delivery systems for curcumin: A review of pharmacodynamic and pharmacokinetic aspects
Saheb, M.,Fereydouni, N.,Nemati, S.,Barreto, G. E.,Johnston, T. P.,Sahebkar, A. (2019) Chitosan-based delivery systems for curcumin: A review of pharmacodynamic and pharmacokinetic aspects. Journal Of Cellular Physiology
NeuroMuscleDB: a Database of Genes Associated with Muscle Development, Neuromuscular Diseases, Ageing, and Neurodegeneration
Baig, M. H.,Rashid, I.,Srivastava, P.,Ahmad, K.,Jan, A. T.,Rabbani, G.,Choi, D.,Barreto, G. E.,Ashraf, G. M.,Lee, E. J.,Choi, I. (2019) NeuroMuscleDB: a Database of Genes Associated with Muscle Development, Neuromuscular Diseases, Ageing, and Neurodegeneration. Molecular Neurobiology
Cholinesterase Inhibitors for Alzheimer Disease: Multitargeting Strategy based on Anti-Alzheimer's Drugs Repositioning
Kabir MT, Uddin MS, Begum MM, Thangapandiyan S, Rahman MS, Aleya L, Mathew B, Ahmed M, Ashraf GM, Barreto GE (2019) Cholinesterase Inhibitors for Alzheimer Disease: Multitargeting Strategy based on Anti-Alzheimer's Drugs Repositioning. Current Pharmaceutical Design
Anti-androgen Drugs in the Treatment of Obsessive-Compulsive Disorder: A Systematic Review
Nomani H, Mohammadpour AH, Moallem SMH, YazdanAbad MJ, Barreto GE, Sahebkar A (2019) Anti-androgen Drugs in the Treatment of Obsessive-Compulsive Disorder: A Systematic Review. Current Medicinal Chemistry
Hormetic effects of curcumin: What is the evidence?
Moghaddam, N. S. A.,Oskouie, M. N.,Butler, A. E.,Petit, P. X.,Barreto, G. E.,Sahebkar, A. (2019) Hormetic effects of curcumin: What is the evidence?. Journal Of Cellular Physiology :10060-10071
Carbon nanomaterials and amyloid beta interactions: Possible potentials in the detection and treatment of Alzheimer's disease
Mohajeri, M.,Behnam, B.,Barreto, G. E.,Sahebkar, A. (2019) Carbon nanomaterials and amyloid beta interactions: Possible potentials in the detection and treatment of Alzheimer's disease. Pharmacological Research
Secretome of Mesenchymal Stem Cells and Its Potential Protective Effects on Brain Pathologies
Baez-Jurado, E.,Hidalgo-Lanussa, O.,Barrera-Bailon, B.,Sahebkar, A.,Ashraf, G. M.,Echeverria, V.,Barreto, G. E. (2019) Secretome of Mesenchymal Stem Cells and Its Potential Protective Effects on Brain Pathologies. Molecular Neurobiology
Curcumin as a therapeutic agent in leukemia
Kouhpeikar, H.,Butler, A. E.,Bamian, F.,Barreto, G. E.,Majeed, M.,Sahebkar, A. (2019) Curcumin as a therapeutic agent in leukemia. Journal Of Cellular Physiology
APOE and Alzheimer's Disease: Evidence Mounts that Targeting APOE4 may Combat Alzheimer's Pathogenesis
Uddin, M. S.,Kabir, M. T.,Al Mamun, A.,Abdel-Daim, M. M.,Barreto, G. E.,Ashraf, G. M. (2018) APOE and Alzheimer's Disease: Evidence Mounts that Targeting APOE4 may Combat Alzheimer's Pathogenesis. Molecular Neurobiology
Gold nanoparticles: A plausible tool to combat neurological bacterial infections in humans
Rizvi, S. M. D.,Hussain, T.,Ahmed, A. B. F.,Alshammari, T. M.,Moin, A.,Ahmed, M. Q.,Barreto, G. E.,Kamal, M. A.,Ashraf, G. M. (2018) Gold nanoparticles: A plausible tool to combat neurological bacterial infections in humans. Biomed Pharmacotherbiomed Pharmacother :7-18
The Role of Efferocytosis in Autoimmune Diseases
Abdolmaleki, F.,Farahani, N.,Gheibi Hayat, S. M.,Pirro, M.,Bianconi, V.,Barreto, G. E.,Sahebkar, A. (2018) The Role of Efferocytosis in Autoimmune Diseases. Frontiers In Immunology :1645-
Growth Factors and Neuroglobin in Astrocyte Protection Against Neurodegeneration and Oxidative Stress
Cabezas, R.,Baez-Jurado, E.,Hidalgo-Lanussa, O.,Echeverria, V.,Ashrad, G. M.,Sahebkar, A.,Barreto, G. E. (2018) Growth Factors and Neuroglobin in Astrocyte Protection Against Neurodegeneration and Oxidative Stress. Mol Neurobiolmol Neurobiol
Pharmacoinformatics and molecular docking reveal potential drug candidates against Schizophrenia to target TAAR6
Tahir, R. A.,Wu, H.,Javed, N.,Khalique, A.,Khan, S. A. F.,Mir, A.,Ahmed, M. S.,Barreto, G. E.,Qing, H.,Ashraf, G. M.,Sehgal, S. A. (2018) Pharmacoinformatics and molecular docking reveal potential drug candidates against Schizophrenia to target TAAR6. Journal Of Cellular Physiology
Macrophage plasticity, polarization and function in response to curcumin, a diet-derived polyphenol, as an immunomodulatory agent
Mohammadi, A.,Blesso, C. N.,Barreto, G. E.,Banach, M.,Majeed, M.,Sahebkar, A. (2018) Macrophage plasticity, polarization and function in response to curcumin, a diet-derived polyphenol, as an immunomodulatory agent. J Nutr Biochemj Nutr Biochem :1-16
Nootropic and Anti-Alzheimer's Actions of Medicinal Plants: Molecular Insight into Therapeutic Potential to Alleviate Alzheimer's Neuropathology
Uddin, M. S.,Al Mamun, A.,Kabir, M. T.,Jakaria, M.,Mathew, B.,Barreto, G. E.,Ashraf, G. M. (2018) Nootropic and Anti-Alzheimer's Actions of Medicinal Plants: Molecular Insight into Therapeutic Potential to Alleviate Alzheimer's Neuropathology. Molecular Neurobiology
Ionic gradient liposomes: Recent advances in the stable entrapment and prolonged released of local anesthetics and anticancer drugs
Fatima, M. T.,Islam, Z.,Ahmad, E.,Barreto, G. E.,Md Ashraf, G. (2018) Ionic gradient liposomes: Recent advances in the stable entrapment and prolonged released of local anesthetics and anticancer drugs. Biomed Pharmacotherbiomed Pharmacother :34-43
Blockade of Neuroglobin Reduces Protection of Conditioned Medium from Human Mesenchymal Stem Cells in Human Astrocyte Model (T98G) Under a Scratch Assay
Baez-Jurado, E.,Vega, G. G.,Aliev, G.,Tarasov, V. V.,Esquinas, P.,Echeverria, V.,Barreto, G. E. (2018) Blockade of Neuroglobin Reduces Protection of Conditioned Medium from Human Mesenchymal Stem Cells in Human Astrocyte Model (T98G) Under a Scratch Assay. Mol Neurobiolmol Neurobiol :2285-2300
Impact of fibrates on circulating cystatin C levels: a systematic review and meta-analysis of clinical trials
Sahebkar, A.,Simental-Mendia, L. E.,Pirro, M.,Montecucco, F.,Carbone, F.,Banach, M.,Barreto, G. E.,Butler, A. E. (2018) Impact of fibrates on circulating cystatin C levels: a systematic review and meta-analysis of clinical trials. Ann Medann Med :485-493
Cotinine Plus Krill Oil Decreased Depressive Behavior, and Increased Astrocytes Survival in the Hippocampus of Mice Subjected to Restraint Stress
Mendoza, C.,Perez-Urrutia, N.,Alvarez-Ricartes, N.,Barreto, G. E.,Perez-Ordas, R.,Iarkov, A.,Echeverria, V. (2018) Cotinine Plus Krill Oil Decreased Depressive Behavior, and Increased Astrocytes Survival in the Hippocampus of Mice Subjected to Restraint Stress. Front Neuroscifront Neurosci :952-
The effect of fasting or calorie restriction on autophagy induction: A review of the literature
Bagherniya, M.,Butler, A. E.,Barreto, G. E.,Sahebkar, A. (2018) The effect of fasting or calorie restriction on autophagy induction: A review of the literature. Ageing Res Revageing Res Rev :183-197
Cotinine: A Therapy for Memory Extinction in Post-traumatic Stress Disorder
Mendoza, C.,Barreto, G. E.,Iarkov, A.,Tarasov, V. V.,Aliev, G.,Echeverria, V. (2018) Cotinine: A Therapy for Memory Extinction in Post-traumatic Stress Disorder. Mol Neurobiolmol Neurobiol :6700-6711
Intranasal Cotinine Plus Krill Oil Facilitates Fear Extinction, Decreases Depressive-Like Behavior, and Increases Hippocampal Calcineurin A Levels in Mice
Alvarez-Ricartes, N.,Oliveros-Matus, P.,Mendoza, C.,Perez-Urrutia, N.,Echeverria, F.,Iarkov, A.,Barreto, G. E.,Echeverria, V. (2018) Intranasal Cotinine Plus Krill Oil Facilitates Fear Extinction, Decreases Depressive-Like Behavior, and Increases Hippocampal Calcineurin A Levels in Mice. Molecular Neurobiology :7949-7960
Peptide based therapeutics and their use for the treatment of neurodegenerative and other diseases
Baig, M. H.,Ahmad, K.,Saeed, M.,Alharbi, A. M.,Barreto, G. E.,Ashraf, G. M.,Choi, I. (2018) Peptide based therapeutics and their use for the treatment of neurodegenerative and other diseases. Biomed Pharmacotherbiomed Pharmacother :574-581
Conditioned Medium of Human Adipose Mesenchymal Stem Cells Increases Wound Closure and Protects Human Astrocytes Following Scratch Assay In Vitro
Baez-Jurado, E.,Hidalgo-Lanussa, O.,Guio-Vega, G.,Ashraf, G. M.,Echeverria, V.,Aliev, G.,Barreto, G. E. (2018) Conditioned Medium of Human Adipose Mesenchymal Stem Cells Increases Wound Closure and Protects Human Astrocytes Following Scratch Assay In Vitro. Mol Neurobiolmol Neurobiol :5377-5392
Urotensin II: Molecular Mechanisms of Biological Activity
Svistunov, A. A.,Tarasov, V. V.,Shakhmardanova, S. A.,Sologova, S. S.,Bagaturiya, E. T.,Chubarev, V. N.,Galenko-Yaroshevsky, P. A.,Avila-Rodriguez, M. F.,Barreto, G. E.,Aliev, G. (2018) Urotensin II: Molecular Mechanisms of Biological Activity. Curr Protein Pept Scicurr Protein Pept Sci :924-934
Sleep Disorders Associated With Alzheimer's Disease: A Perspective
Brzecka, A.,Leszek, J.,Ashraf, G. M.,Ejma, M.,Avila-Rodriguez, M. F.,Yarla, N. S.,Tarasov, V. V.,Chubarev, V. N.,Samsonova, A. N.,Barreto, G. E.,Aliev, G. (2018) Sleep Disorders Associated With Alzheimer's Disease: A Perspective. Front Neuroscifront Neurosci :330-
Correction to: Cotinine: A Therapy for Memory Extinction in Post-traumatic Stress Disorder
Mendoza, C.,Barreto, G. E.,Iarkov, A.,Tarasov, V. V.,Aliev, G.,Echeverria, V. (2018) Correction to: Cotinine: A Therapy for Memory Extinction in Post-traumatic Stress Disorder. Mol Neurobiolmol Neurobiol :6712-
Trans-aconitic acid inhibits the growth and photosynthesis of Glycine max
Bortolo, Tdsc,Marchiosi, R.,Vigano, J.,Siqueira-Soares, R. C.,Ferro, A. P.,Barreto, G. E.,Bido, G. S.,Abrahao, J.,Dos Santos, W. D.,Ferrarese-Filho, O. (2018) Trans-aconitic acid inhibits the growth and photosynthesis of Glycine max. Plant Physiol Biochemplant Physiol Biochem :490-496
Mitochondrial Neuroglobin Is Necessary for Protection Induced by Conditioned Medium from Human Adipose-Derived Mesenchymal Stem Cells in Astrocytic Cells Subjected to Scratch and Metabolic Injury
Baez-Jurado, E.,Guio-Vega, G.,Hidalgo-Lanussa, O.,Gonzalez, J.,Echeverria, V.,Ashraf, G. M.,Sahebkar, A.,Barreto, G. E. (2018) Mitochondrial Neuroglobin Is Necessary for Protection Induced by Conditioned Medium from Human Adipose-Derived Mesenchymal Stem Cells in Astrocytic Cells Subjected to Scratch and Metabolic Injury. Mol Neurobiolmol Neurobiol
Cellular and Molecular Aspects of Parkinson Treatment: Future Therapeutic Perspectives
Jamebozorgi, K.,Taghizadeh, E.,Rostami, D.,Pormasoumi, H.,Barreto, G. E.,Hayat, S. M. G.,Sahebkar, A. (2018) Cellular and Molecular Aspects of Parkinson Treatment: Future Therapeutic Perspectives. Mol Neurobiolmol Neurobiol
Author Correction: Pyridoxine dipharmacophore derivatives as potent glucokinase activators for the treatment of type 2 diabetes mellitus
Dzyurkevich, M. S.,Babkov, D. A.,Shtyrlin, N. V.,Mayka, O. Y.,Iksanova, A. G.,Vassiliev, P. M.,Balakin, K. V.,Spasov, A. A.,Tarasov, V. V.,Barreto, G.,Shtyrlin, Y. G.,Aliev, G. (2018) Author Correction: Pyridoxine dipharmacophore derivatives as potent glucokinase activators for the treatment of type 2 diabetes mellitus. Sci Repsci Rep :6489-
New ABCC2 rs3740066 and rs2273697 Polymorphisms Identified in a Healthy Colombian Cohort
Bustos-Cruz, R. H.,Martinez, L. R.,Garcia, J. C.,Barreto, G. E.,Suarez, F. (2018) New ABCC2 rs3740066 and rs2273697 Polymorphisms Identified in a Healthy Colombian Cohort. Pharmaceuticspharmaceutics
The cytochrome P450 isoenzyme and some new opportunities for the prediction of negative drug interaction in vivo
Sychev, D. A.,Ashraf, G. M.,Svistunov, A. A.,Maksimov, M. L.,Tarasov, V. V.,Chubarev, V. N.,Otdelenov, V. A.,Denisenko, N. P.,Barreto, G. E.,Aliev, G. (2018) The cytochrome P450 isoenzyme and some new opportunities for the prediction of negative drug interaction in vivo. Drug Design Development And Therapy :1147-1156
Inhibiting Effect of Zinc Oxide Nanoparticles on Advanced Glycation Products and Oxidative Modifications: a Potential Tool to Counteract Oxidative Stress in Neurodegenerative Diseases
Ashraf, J. M.,Ansari, M. A.,Fatma, S.,Abdullah, S. M. S.,Iqbal, J.,Madkhali, A.,Hamali, A. H.,Ahmad, S.,Jerah, A.,Echeverria, V.,Barreto, G. E.,Ashraf, G. M. (2018) Inhibiting Effect of Zinc Oxide Nanoparticles on Advanced Glycation Products and Oxidative Modifications: a Potential Tool to Counteract Oxidative Stress in Neurodegenerative Diseases. Mol Neurobiolmol Neurobiol :7438-7452
Extracts of Physalis peruviana Protect Astrocytic Cells Under Oxidative Stress With Rotenone
Areiza-Mazo, N.,Robles, J.,Zamudio-Rodriguez, J. A.,Giraldez, L.,Echeverria, V.,Barrera-Bailon, B.,Aliev, G.,Sahebkar, A.,Ashraf, G. M.,Barreto, G. E. (2018) Extracts of Physalis peruviana Protect Astrocytic Cells Under Oxidative Stress With Rotenone. Front Chemfront Chem :276-
Tibolone Reduces Oxidative Damage and Inflammation in Microglia Stimulated with Palmitic Acid through Mechanisms Involving Estrogen Receptor Beta
Hidalgo-Lanussa, O.,Avila-Rodriguez, M.,Baez-Jurado, E.,Zamudio, J.,Echeverria, V.,Garcia-Segura, L. M.,Barreto, G. E. (2018) Tibolone Reduces Oxidative Damage and Inflammation in Microglia Stimulated with Palmitic Acid through Mechanisms Involving Estrogen Receptor Beta. Mol Neurobiolmol Neurobiol :5462-5477
Lignin-induced growth inhibition in soybean exposed to iron oxide nanoparticles
Cunha Lopes, T. L.,de Cassia Siqueira-Soares, R.,Goncalves de Almeida, G. H.,Romano de Melo, G. S.,Barreto, G. E.,de Oliveira, D. M.,Dos Santos, W. D.,Ferrarese-Filho, O.,Marchiosi, R. (2018) Lignin-induced growth inhibition in soybean exposed to iron oxide nanoparticles. Chemospherechemosphere :226-234
Correction to: Intranasal Cotinine Plus Krill Oil Facilitates Fear Extinction, Decreases Depressive-Like Behavior, and Increases Hippocampal Calcineurin A Levels in Mice
Alvarez-Ricartes, N.,Oliveros-Matus, P.,Mendoza, C.,Perez-Urrutia, N.,Echeverria, F.,Iarkov, A.,Barreto, G. E.,Echeverria, V. (2018) Correction to: Intranasal Cotinine Plus Krill Oil Facilitates Fear Extinction, Decreases Depressive-Like Behavior, and Increases Hippocampal Calcineurin A Levels in Mice. Mol Neurobiolmol Neurobiol :7961-
Tibolone Preserves Mitochondrial Functionality and Cell Morphology in Astrocytic Cells Treated with Palmitic Acid
Gonzalez-Giraldo, Y.,Garcia-Segura, L. M.,Echeverria, V.,Barreto, G. E. (2018) Tibolone Preserves Mitochondrial Functionality and Cell Morphology in Astrocytic Cells Treated with Palmitic Acid. Mol Neurobiolmol Neurobiol :4453-4462
Hair in Parkinson's disease patients exhibits differences in Calcium, Iron and Zinc concentrations measured by flame atomic absorption spectrometry - FAAS
Dos Santos, A. B.,Kohlmeier, K. A.,Rocha, M. E.,Barreto, G. E.,Barreto, J. A.,de Souza, A. C. A.,Bezerra, M. A. (2018) Hair in Parkinson's disease patients exhibits differences in Calcium, Iron and Zinc concentrations measured by flame atomic absorption spectrometry - FAAS. J Trace Elem Med Biolj Trace Elem Med Biol :134-139
Role of GTPases in the Regulation of Mitochondrial Dynamics in Alzheimer's Disease and CNS-Related Disorders
Alexiou, A.,Soursou, G.,Chatzichronis, S.,Gasparatos, E.,Kamal, M. A.,Yarla, N. S.,Perveen, A.,Barreto, G. E.,Ashraf, G. M. (2018) Role of GTPases in the Regulation of Mitochondrial Dynamics in Alzheimer's Disease and CNS-Related Disorders. Mol Neurobiolmol Neurobiol
RAGE-TLR Crosstalk Sustains Chronic Inflammation in Neurodegeneration
Gasiorowski, K.,Brokos, B.,Echeverria, V.,Barreto, G. E.,Leszek, J. (2018) RAGE-TLR Crosstalk Sustains Chronic Inflammation in Neurodegeneration. Mol Neurobiolmol Neurobiol :1463-1476
An optimized alternative for phenolic compound-extraction of strawberry bagasse agro-industrial residues
Felix, A.C.S.;Novaes, C.G.;Rocha, M.P.;Barreto, G.E.;Franco, M.;do Nascimento Junior, B.B.;Alvarez, L.D.G.; (2018) An optimized alternative for phenolic compound-extraction of strawberry bagasse agro-industrial residues. Journal Of Microbiology, Biotechnology And Food Sciences
Curcumin as a therapeutic candidate for multiple sclerosis: Molecular mechanisms and targets
Ghanaatian, N.,Lashgari, N. A.,Abdolghaffari, A. H.,Rajaee, S. M.,Panahi, Y.,Barreto, G. E.,Butler, A. E.,Sahebkar, A. (2018) Curcumin as a therapeutic candidate for multiple sclerosis: Molecular mechanisms and targets. J Cell Physiolj Cell Physiol
Modulation of heat shock proteins by statins
Forouzanfar, F.,Butler, A. E.,Banach, M.,Barreto, G. E.,Sahbekar, A. (2018) Modulation of heat shock proteins by statins. Pharmacol Respharmacol Res :134-144
The Synthetic Steroid Tibolone Decreases Reactive Gliosis and Neuronal Death in the Cerebral Cortex of Female Mice After a Stab Wound Injury
Crespo-Castrillo, A.,Yanguas-Casas, N.,Arevalo, M. A.,Azcoitia, I.,Barreto, G. E.,Garcia-Segura, L. M. (2018) The Synthetic Steroid Tibolone Decreases Reactive Gliosis and Neuronal Death in the Cerebral Cortex of Female Mice After a Stab Wound Injury. Mol Neurobiolmol Neurobiol :8651-8667
Cell therapy for spinal cord injury with olfactory ensheathing glia cells (OECs)
Gomez, R. M.,Sanchez, M. Y.,Portela-Lomba, M.,Ghotme, K.,Barreto, G. E.,Sierra, J.,Moreno-Flores, M. T. (2018) Cell therapy for spinal cord injury with olfactory ensheathing glia cells (OECs). Gliaglia :1267-1301
Combined Strategy for a Reliable Evaluation of Spinal Cord Injury Using an in vivo Model
Gomez, R. M.,Ghotme, K.,Nino, J. J.,Quiroz-Padilla, M.,Vargas, D.,Dominguez, A. R.,Barreto, G. E.,Sanchez, M. Y. (2018) Combined Strategy for a Reliable Evaluation of Spinal Cord Injury Using an in vivo Model. Cent Nerv Syst Agents Med Chemcent Nerv Syst Agents Med Chem :49-57
Mild cognitive impairment due to Alzheimer disease: Contemporary approaches to diagnostics and pharmacological intervention
Bachurin, S. O.,Gavrilova, S. I.,Samsonova, A.,Barreto, G. E.,Aliev, G. (2018) Mild cognitive impairment due to Alzheimer disease: Contemporary approaches to diagnostics and pharmacological intervention. Pharmacol Respharmacol Res :216-226
PDGF-BB Preserves Mitochondrial Morphology, Attenuates ROS Production, and Upregulates Neuroglobin in an Astrocytic Model Under Rotenone Insult
Cabezas, R.,Vega-Vela, N. E.,Gonzalez-Sanmiguel, J.,Gonzalez, J.,Esquinas, P.,Echeverria, V.,Barreto, G. E. (2018) PDGF-BB Preserves Mitochondrial Morphology, Attenuates ROS Production, and Upregulates Neuroglobin in an Astrocytic Model Under Rotenone Insult. Mol Neurobiolmol Neurobiol :3085-3095
Sex differences in Parkinson's disease: Features on clinical symptoms, treatment outcome, sexual hormones and genetics
Jurado-Coronel, J. C.,Cabezas, R.,Avila Rodriguez, M. F.,Echeverria, V.,Garcia-Segura, L. M.,Barreto, G. E. (2018) Sex differences in Parkinson's disease: Features on clinical symptoms, treatment outcome, sexual hormones and genetics. Front Neuroendocrinolfront Neuroendocrinol :18-30
Pharmacological Aspects of Neuro-Immune Interactions
Tarasov, V. V.,Kudryashov, N. V.,Chubarev, V. N.,Kalinina, T. S.,Barreto, G. E.,Ashraf, G. M.,Aliev, G. (2018) Pharmacological Aspects of Neuro-Immune Interactions. Current Pharmaceutical Design :15-21
Corrigendum to "Mild cognitive impairment due to Alzheimer disease: Contemporary approaches to diagnostics and pharmacological intervention" [Pharmacol. Res. 129 (2018) 216-226]
Bachurin, S. O.,Gavrilova, S. I.,Samsonova, A.,Barreto, G. E.,Aliev, G. (2018) Corrigendum to "Mild cognitive impairment due to Alzheimer disease: Contemporary approaches to diagnostics and pharmacological intervention" [Pharmacol. Res. 129 (2018) 216-226]. Pharmacol Respharmacol Res :245-
Correction to: Growth Factors and Neuroglobin in Astrocyte Protection Against Neurodegeneration and Oxidative Stress
Cabezas, R.,Baez-Jurado, E.,Hidalgo-Lanussa, O.,Echeverria, V.,Ashraf, G. M.,Sahebkar, A.,Barreto, G. E. (2018) Correction to: Growth Factors and Neuroglobin in Astrocyte Protection Against Neurodegeneration and Oxidative Stress. Mol Neurobiolmol Neurobiol
Neuroactive steroids, neurosteroidogenesis and sex
Giatti, S.,Garcia-Segura, L. M.,Barreto, G. E.,Melcangi, R. C. (2018) Neuroactive steroids, neurosteroidogenesis and sex. Prog Neurobiolprog Neurobiol
Chemosensitizing Activity of Histone Deacetylases Inhibitory Cyclic Hydroxamic Acids for Combination Chemotherapy of Lymphatic Leukemia
Mishchenko, D. V.,Neganova, M. E.,Klimanova, E. N.,Sashenkova, T. E.,Klochkov, S. G.,Shevtsova, E. F.,Vystorop, I. V.,Tarasov, V. V.,Chubarev, V. N.,Samsonova, A. N.,Ashraf, G. M.,Barreto, G.,Yarla, N. S.,Aliev, G. (2018) Chemosensitizing Activity of Histone Deacetylases Inhibitory Cyclic Hydroxamic Acids for Combination Chemotherapy of Lymphatic Leukemia. Curr Cancer Drug Targetscurr Cancer Drug Targets :365-371
Genome-Wide Expression Profiles for Ischemic Stroke: A Meta-Analysis
Moreno-Ramirez, C. E.,Gutierrez-Garzon, E.,Barreto, G. E.,Forero, D. A. (2018) Genome-Wide Expression Profiles for Ischemic Stroke: A Meta-Analysis. J Stroke Cerebrovasc Disj Stroke Cerebrovasc Dis :3336-3341
Gliomas: New Perspectives in Diagnosis, Treatment and Prognosis
Ghotme, K. A.,Barreto, G. E.,Echeverria, V.,Gonzalez, J.,Bustos, R. H.,Sanchez, M.,Leszek, J.,Yarla, N. S.,Gomez, R. M.,Tarasov, V. V.,Ashraf, G. M.,Aliev, G. (2017) Gliomas: New Perspectives in Diagnosis, Treatment and Prognosis. Curr Top Med Chemcurr Top Med Chem :1438-1447
Securinine Derivatives as Potential Anti-amyloid Therapeutic Approach
Neganova, M. E.,Klochkov, S. G.,Petrova, L. N.,Shevtsova, E. F.,Afanasieva, S. V.,Chudinova, E. S.,Fisenko, V. P.,Bachurin, S. O.,Barreto, G. E.,Aliev, G. (2017) Securinine Derivatives as Potential Anti-amyloid Therapeutic Approach. Cns Neurol Disord Drug Targetscns Neurol Disord Drug Targets :351-355
Astrocytes and endoplasmic reticulum stress: A bridge between obesity and neurodegenerative diseases
Martin-Jimenez, C. A.,Garcia-Vega, A.,Cabezas, R.,Aliev, G.,Echeverria, V.,Gonzalez, J.,Barreto, G. E. (2017) Astrocytes and endoplasmic reticulum stress: A bridge between obesity and neurodegenerative diseases. Prog Neurobiolprog Neurobiol :45-68
Neuroprotection in Hypoxic-Ischemic Brain Injury Targeting Glial Cells
Herrera, M. I.,Mucci, S.,Barreto, G. E.,Kolliker-Frers, R.,Capani, F. (2017) Neuroprotection in Hypoxic-Ischemic Brain Injury Targeting Glial Cells. Curr Pharm Descurr Pharm Des :3899-3906
Portacaval shunting causes differential mitochondrial superoxide production in brain regions
Kosenko, E. A.,Tikhonova, L. A.,Alilova, G. A.,Montoliu, C.,Barreto, G. E.,Aliev, G.,Kaminsky, Y. G. (2017) Portacaval shunting causes differential mitochondrial superoxide production in brain regions. Free Radic Biol Medfree Radic Biol Med :109-118
Cotinine improves visual recognition memory and decreases cortical Tau phosphorylation in the Tg6799 mice
Grizzell, J. A.,Patel, S.,Barreto, G. E.,Echeverria, V. (2017) Cotinine improves visual recognition memory and decreases cortical Tau phosphorylation in the Tg6799 mice. Prog Neuropsychopharmacol Biol Psychiatryprog Neuropsychopharmacol Biol Psychiatry :75-81
4'-Chlorodiazepam Protects Mitochondria in T98G Astrocyte Cell Line from Glucose Deprivation
Baez, E.,Guio-Vega, G. P.,Echeverria, V.,Sandoval-Rueda, D. A.,Barreto, G. E. (2017) 4'-Chlorodiazepam Protects Mitochondria in T98G Astrocyte Cell Line from Glucose Deprivation. Neurotox Resneurotox Res :163-171
Neuroglial Cell Cryopreservation in Appropriate Inductive Conditions
Gomez, R. M.,Dominguez-Sanchez, M. A.,Sanchez, M. Y.,Barreto, G. E. (2017) Neuroglial Cell Cryopreservation in Appropriate Inductive Conditions. Curr Pharm Descurr Pharm Des :4145-4153
Nanotechnology in Neurosciences: An Approach
Bustos Cruz, R. H.,Sanchez, M. M.,Dominguez-Sanchez, M. A.,Barreto, G. E.,Lancheros, D.,Reynolds, J. (2017) Nanotechnology in Neurosciences: An Approach. Curr Pharm Descurr Pharm Des :4154-4169
Approaches of the Transcriptomic Analysis in Astrocytes: Potential Pharmacological Targets
Barreto, G. E.,Gomez, R. M.,Bustos, R. H.,Forero, D. A.,Aliev, G.,Tarasov, V. V.,Yarla, N. S.,Echeverria, V.,Gonzalez, J. (2017) Approaches of the Transcriptomic Analysis in Astrocytes: Potential Pharmacological Targets. Curr Pharm Descurr Pharm Des :4189-4197
Metabolic Abnormalities of Erythrocytes as a Risk Factor for Alzheimer's Disease
Kosenko, E. A.,Tikhonova, L. A.,Montoliu, C.,Barreto, G. E.,Aliev, G.,Kaminsky, Y. G. (2017) Metabolic Abnormalities of Erythrocytes as a Risk Factor for Alzheimer's Disease. Front Neuroscifront Neurosci :728-
Intranasal cotinine improves memory, and reduces depressive-like behavior, and GFAP+ cells loss induced by restraint stress in mice
Perez-Urrutia, N.,Mendoza, C.,Alvarez-Ricartes, N.,Oliveros-Matus, P.,Echeverria, F.,Grizzell, J. A.,Barreto, G. E.,Iarkov, A.,Echeverria, V. (2017) Intranasal cotinine improves memory, and reduces depressive-like behavior, and GFAP+ cells loss induced by restraint stress in mice. Exp Neurolexp Neurol :211-221
Implication of Gastric Cancer Molecular Genetic Markers in Surgical Practice
Nemtsova, M. V.,Strelnikov, V. V.,Tanas, A. S.,Bykov,, II,Zaletaev, D. V.,Rudenko, V. V.,Glukhov, A. I.,Kchorobrich, T. V.,Li, Y.,Tarasov, V. V.,Barreto, G. E.,Aliev, G. (2017) Implication of Gastric Cancer Molecular Genetic Markers in Surgical Practice. Curr Genomicscurr Genomics :408-415
Synthesis of Saccharumoside-B analogue with potential of antiproliferative and pro-apoptotic activities
Rayavarapu, S.,Yarla, N. S.,Kadiri, S. K.,Bishayee, A.,Vidavalur, S.,Tadikonda, R.,Basha, M.,Pidugu, V. R.,Dowluru, Ksvgk,Lakappa, D. B.,Kamal, M. A.,Md Ashraf, G.,Tarasov, V. V.,Chubarev, V. N.,Klochkov, S. G.,Barreto, G. E.,Bachurin, S. O.,Aliev, G. (2017) Synthesis of Saccharumoside-B analogue with potential of antiproliferative and pro-apoptotic activities. Sci Repsci Rep :8309-
Mixture Design and Doehlert Matrix for the Optimization of the Extraction of Phenolic Compounds from Spondias mombin L Apple Bagasse Agroindustrial Residues
Santos Felix, A. C.,Novaes, C. G.,Pires Rocha, M.,Barreto, G. E.,do Nascimento, B. B., Jr.,Giraldez Alvarez, L. D. (2017) Mixture Design and Doehlert Matrix for the Optimization of the Extraction of Phenolic Compounds from Spondias mombin L Apple Bagasse Agroindustrial Residues. Front Chemfront Chem :116-
A Systematic In-silico Analysis of Helicobacter pylori Pathogenic Islands for Identification of Novel Drug Target Candidates
Nammi, D.,Yarla, N. S.,Chubarev, V. N.,Tarasov, V. V.,Barreto, G. E.,Pasupulati, A. M. C.,Aliev, G.,Neelapu, N. R. R. (2017) A Systematic In-silico Analysis of Helicobacter pylori Pathogenic Islands for Identification of Novel Drug Target Candidates. Curr Genomicscurr Genomics :450-465
Pyridoxine dipharmacophore derivatives as potent glucokinase activators for the treatment of type 2 diabetes mellitus
Dzyurkevich, M. S.,Babkov, D. A.,Shtyrlin, N. V.,Mayka, O. Y.,Iksanova, A. G.,Vassiliev, P. M.,Balakin, K. V.,Spasov, A. A.,Tarasov, V. V.,Barreto, G.,Shtyrlin, Y. G.,Aliev, G. (2017) Pyridoxine dipharmacophore derivatives as potent glucokinase activators for the treatment of type 2 diabetes mellitus. Sci Repsci Rep :16072-
Ginkgo biloba as an Alternative Medicine in the Treatment of Anxiety in Dementia and other Psychiatric Disorders
Singh, S. K.,Barreto, G. E.,Aliev, G.,Echeverria, V. (2017) Ginkgo biloba as an Alternative Medicine in the Treatment of Anxiety in Dementia and other Psychiatric Disorders. Curr Drug Metabcurr Drug Metab :112-119
Editorial: Genomics and Epigenomics of Tumor and Aging Cells
Aliev, G.,Barreto, G. E.,Cacabelos, R. (2017) Editorial: Genomics and Epigenomics of Tumor and Aging Cells. Curr Genomicscurr Genomics :375-377
Novel conjugates of aminoadamantanes with carbazole derivatives as potential multitarget agents for AD treatment
Bachurin, S. O.,Shevtsova, E. F.,Makhaeva, G. F.,Grigoriev, V. V.,Boltneva, N. P.,Kovaleva, N. V.,Lushchekina, S. V.,Shevtsov, P. N.,Neganova, M. E.,Redkozubova, O. M.,Bovina, E. V.,Gabrelyan, A. V.,Fisenko, V. P.,Sokolov, V. B.,Aksinenko, A. Y.,Echeverria, V.,Barreto, G. E.,Aliev, G. (2017) Novel conjugates of aminoadamantanes with carbazole derivatives as potential multitarget agents for AD treatment. Sci Repsci Rep :45627-
L-Type Calcium Channels Modulation by Estradiol
Vega-Vela, N. E.,Osorio, D.,Avila-Rodriguez, M.,Gonzalez, J.,Garcia-Segura, L. M.,Echeverria, V.,Barreto, G. E. (2017) L-Type Calcium Channels Modulation by Estradiol. Mol Neurobiolmol Neurobiol :4996-5007
Advances in Medicinal Plants with Effects on Anxiety Behavior Associated to Mental and Health Conditions
Barreto, G. E.,Avila-Rodriguez, M.,Foitzick, M.,Aliev, G.,Echeverria, V. (2017) Advances in Medicinal Plants with Effects on Anxiety Behavior Associated to Mental and Health Conditions. Curr Med Chemcurr Med Chem :411-423
Anthocyanins: Multi-Target Agents for Prevention and Therapy of Chronic Diseases
Putta, S.,Yarla, N. S.,Peluso, I.,Tiwari, D. K.,Reddy, G. V.,Giri, P. V.,Kumar, N.,Malla, R.,Rachel, V.,Bramhachari, P. V.,Reddy, D. Rs,Bade, R.,Mannarapu, M.,Barreto, G. E.,Lu, D. Y.,Tarasov, V. V.,Chubarev, V. N.,Ribeiro, F. F.,Scotti, L.,Scotti, M. T.,Kamal, M. A.,Ashraf, G. M.,Aliev, G.,Perry, G.,Sarker, S. D.,Rao, C. V.,Bishayee, A. (2017) Anthocyanins: Multi-Target Agents for Prevention and Therapy of Chronic Diseases. Curr Pharm Descurr Pharm Des :6321-6346
Relationship Between Obesity, Alzheimer's Disease, and Parkinson's Disease: an Astrocentric View
Martin-Jimenez, C. A.,Gaitan-Vaca, D. M.,Echeverria, V.,Gonzalez, J.,Barreto, G. E. (2017) Relationship Between Obesity, Alzheimer's Disease, and Parkinson's Disease: an Astrocentric View. Mol Neurobiolmol Neurobiol :7096-7115
Genome-Scale Reconstruction of the Human Astrocyte Metabolic Network
Martin-Jimenez, C. A.,Salazar-Barreto, D.,Barreto, G. E.,Gonzalez, J. (2017) Genome-Scale Reconstruction of the Human Astrocyte Metabolic Network. Front Aging Neuroscifront Aging Neurosci :23-
Nanotechnology for Alzheimer Disease
Leszek, J.,Md Ashraf, G.,Tse, W. H.,Zhang, J.,Gasiorowski, K.,Avila-Rodriguez, M. F.,Tarasov, V. V.,Barreto, G. E.,Klochkov, S. G.,Bachurin, S. O.,Aliev, G. (2017) Nanotechnology for Alzheimer Disease. Curr Alzheimer Rescurr Alzheimer Res :1182-1189
Diabetes Mellitus and Male Aging: Pharmacotherapeutics and Clinical Implications
Putta, S.,Peluso, I.,Yarla, N. S.,Kilari, E. K.,Bishayee, A.,Lu, D. Y.,Barreto, G. E.,Ashraf, G. M.,Scotti, L.,Scotti, M. T.,Singla, R. K.,Alexiou, T.,Atanasov, A. G.,Tarasov, V. V.,Bramhachari, P. V.,Imandi, S. B.,Chintala, M.,Sharma, B.,Reale, M.,Filosa, R.,Aliev, G.,Kamal, M. A. (2017) Diabetes Mellitus and Male Aging: Pharmacotherapeutics and Clinical Implications. Curr Pharm Descurr Pharm Des :4475-4483
Metabolic and Inflammatory Adaptation of Reactive Astrocytes: Role of PPARs
Iglesias, J.,Morales, L.,Barreto, G. E. (2017) Metabolic and Inflammatory Adaptation of Reactive Astrocytes: Role of PPARs. Mol Neurobiolmol Neurobiol :2518-2538
Is VEGF a Key Target of Cotinine and Other Potential Therapies Against Alzheimer Disease?
Echeverria, V.,Barreto, G. E.,Avila-Rodriguezc, M.,Tarasov, V. V.,Aliev, G. (2017) Is VEGF a Key Target of Cotinine and Other Potential Therapies Against Alzheimer Disease?. Curr Alzheimer Rescurr Alzheimer Res :1155-1163
Genomics and epigenomics of tumor and aging cells
Aliev, G.;Barreto, G.E.;Cacabelos, R.; (2017) Genomics and epigenomics of tumor and aging cells. Current Genomics
Mitochondrial Permeability Transition Pore as a Suitable Targ e t for Neuroprotective Agents Against Alzheimer's Disease
Shevtsova, E. F.,Vinogradova, D. V.,Neganova, M. E.,Avila-Rodriguez, M.,Ashraf, G. M.,Barreto, G. E.,Bachurin, S. O.,Aliev, G. (2017) Mitochondrial Permeability Transition Pore as a Suitable Targ e t for Neuroprotective Agents Against Alzheimer's Disease. Cns Neurol Disord Drug Targetscns Neurol Disord Drug Targets :677-685
Medicinal Plants as Protective Strategies Against Parkinson's Disease
Mazo, N. A.,Echeverria, V.,Cabezas, R.,Avila-Rodriguez, M.,Tarasov, V. V.,Yarla, N. S.,Aliev, G.,Barreto, G. E. (2017) Medicinal Plants as Protective Strategies Against Parkinson's Disease. Curr Pharm Descurr Pharm Des :4180-4188
Implications of farnesyltransferase and its inhibitors as a promising strategy for cancer therapy
Klochkov, S. G.,Neganova, M. E.,Yarla, N. S.,Parvathaneni, M.,Sharma, B.,Tarasov, V. V.,Barreto, G.,Bachurin, S. O.,Ashraf, G. M.,Aliev, G. (2017) Implications of farnesyltransferase and its inhibitors as a promising strategy for cancer therapy. Semin Cancer Biolsemin Cancer Biol
SUR1 Receptor Interaction with Hesperidin and Linarin Predicts Possible Mechanisms of Action of Valeriana officinalis in Parkinson
Santos, G.,Giraldez-Alvarez, L. D.,Avila-Rodriguez, M.,Capani, F.,Galembeck, E.,Neto, A. G.,Barreto, G. E.,Andrade, B. (2016) SUR1 Receptor Interaction with Hesperidin and Linarin Predicts Possible Mechanisms of Action of Valeriana officinalis in Parkinson. Front Aging Neuroscifront Aging Neurosci :97-
Targeting the Nicotinic Acetylcholine Receptors (nAChRs) in Astrocytes as a Potential Therapeutic Target in Parkinsonâs Disease
Juan Jurado-Coronel;Marco Avila-Rodriguez;Francisco Capani;Janneth Gonzalez;Valentina Moran;George Barreto; (2016) Targeting the Nicotinic Acetylcholine Receptors (nAChRs) in Astrocytes as a Potential Therapeutic Target in Parkinsonâs Disease. Current pharmaceutical design
Role of microfluidics in blood-brain barrier permeability cell culture modeling: Relevance to CNS disorders
Rusanov, A.L.;Luzgina, N.G.;Barreto, G.E.;Aliev, G.; (2016) Role of microfluidics in blood-brain barrier permeability cell culture modeling: Relevance to CNS disorders. CNS & neurological disorders drug targets
Ischemic Stroke and Six Genetic Variants in CRP, EPHX2, FGA, and NOTCH3 Genes: A Meta-Analysis
Gonzalez-Giraldo, Y.,Barreto, G. E.,Fava, C.,Forero, D. A. (2016) Ischemic Stroke and Six Genetic Variants in CRP, EPHX2, FGA, and NOTCH3 Genes: A Meta-Analysis. J Stroke Cerebrovasc Disj Stroke Cerebrovasc Dis :2284-9
Metabolic Changes Following Perinatal Asphyxia: Role of Astrocytes and Their Interaction with Neurons
Logica, T.,Riviere, S.,Holubiec, M. I.,Castilla, R.,Barreto, G. E.,Capani, F. (2016) Metabolic Changes Following Perinatal Asphyxia: Role of Astrocytes and Their Interaction with Neurons. Front Aging Neuroscifront Aging Neurosci :116-
Alterations in Glucose Metabolism on Cognition: A Possible Link Between Diabetes and Dementia
Rodrigo González-Reyes;Gjumrakch Aliev;Marco Avila-Rodrigues;George Barreto; (2016) Alterations in Glucose Metabolism on Cognition: A Possible Link Between Diabetes and Dementia. Current pharmaceutical design
Role of Microfluidics in Blood-Brain Barrier Permeability Cell Culture Modeling: Relevance to CNS Disorders
Rusanov, A. L.,Luzgina, N. G.,Barreto, G. E.,Aliev, G. (2016) Role of Microfluidics in Blood-Brain Barrier Permeability Cell Culture Modeling: Relevance to CNS Disorders. Cns Neurol Disord Drug Targetscns Neurol Disord Drug Targets :301-9
Targeting astrocytes in brain injuries: A translational research approach
Barreto, G. E. (2016) Targeting astrocytes in brain injuries: A translational research approach. Prog Neurobiolprog Neurobiol :1-4
Implication of green tea as a possible therapeutic approach for Parkinson disease
Jurado-Coronel, J.C.;Ãvila-Rodriguez, M.;Echeverria, V.;Hidalgo, O.A.;Gonzalez, J.;Aliev, G.;Barreto, G.E.; (2016) Implication of green tea as a possible therapeutic approach for Parkinson disease. CNS & neurological disorders drug targets
Alterations in glucose metabolism on cognition: A possible link between diabetes and dementia
González-Reyes, R.E.;Aliev, G.;Ãvila-Rodrigues, M.;Barreto, G.E.; (2016) Alterations in glucose metabolism on cognition: A possible link between diabetes and dementia. Current pharmaceutical design
Inflammatory Mechanisms and Oxidative Stress as Key Factors Responsible for Progression of Neurodegeneration: Role of Brain Innate Immune System
Leszek, J.,Barreto, G. E.,Gasiorowski, K.,Koutsouraki, E.,Avila-Rodrigues, M.,Aliev, G. (2016) Inflammatory Mechanisms and Oxidative Stress as Key Factors Responsible for Progression of Neurodegeneration: Role of Brain Innate Immune System. Cns Neurol Disord Drug Targetscns Neurol Disord Drug Targets :329-36
Glial modulation by N-acylethanolamides in brain injury and neurodegeneration
Herrera, M.I.;Kölliker-Frers, R.;Barreto, G.;Blanco, E.;Capani, F.; (2016) Glial modulation by N-acylethanolamides in brain injury and neurodegeneration. Frontiers In Aging Neuroscience
Regulation of astroglia by gonadal steroid hormones under physiological and pathological conditions
Acaz-Fonseca, E.,Avila-Rodriguez, M.,Garcia-Segura, L. M.,Barreto, G. E. (2016) Regulation of astroglia by gonadal steroid hormones under physiological and pathological conditions. Prog Neurobiolprog Neurobiol :5-26
Microglial dependent protective effects of neuroactive steroids
Lanussa, O.H.;Ãvila-Rodriguez, M.;GarcÃa-Segura, L.M.;González, J.;Echeverria, V.;Aliev, G.;Barreto, G.E.; (2016) Microglial dependent protective effects of neuroactive steroids. CNS & neurological disorders drug targets
Neuroprotective effects of the catalytic subunit of telomerase: A potential therapeutic target in the central nervous system
Gonzalez-Giraldo, Y.,Forero, D. A.,Echeverria, V.,Gonzalez, J.,Avila-Rodriguez, M.,Garcia-Segura, L. M.,Barreto, G. E. (2016) Neuroprotective effects of the catalytic subunit of telomerase: A potential therapeutic target in the central nervous system. Ageing Res Revageing Res Rev :37-45
Approaches for the development of drugs for treatment of obesity and metabolic syndrome
Maksimov, M.L.;Svistunov, A.A.;Tarasov, V.V.;Chubarev, V.N.;Ãvila-Rodriguez, M.;Barreto, G.E.;Dralova, O.V.;Aliev, G.; (2016) Approaches for the development of drugs for treatment of obesity and metabolic syndrome. Current pharmaceutical design
Microglial dependent protective effects of neuroactive steroids
Lanussa, O. H.,Avila-Rodriguez, M.,Garcia-Segura, L. M.,Gonzalez, J.,Echeverria, V.,Aliev, G.,Barreto, G. E. (2016) Microglial dependent protective effects of neuroactive steroids. Cns Neurol Disord Drug Targetscns Neurol Disord Drug Targets :242-9
Role of neuroinflammation and sex hormones in war-related PTSD
Mendoza, C.,Barreto, G. E.,Avila-Rodriguez, M.,Echeverria, V. (2016) Role of neuroinflammation and sex hormones in war-related PTSD. Mol Cell Endocrinolmol Cell Endocrinol :266-77
Inflammatory mechanisms and oxidative stress as key factors responsible for progression of neurodegeneration: Role of brain innate immune system
Leszek, J.;Barreto, G.E.;GÄ siorowski, K.;Koutsouraki, E.;Ãvila-Rodrigues, M.;Aliev, G.; (2016) Inflammatory mechanisms and oxidative stress as key factors responsible for progression of neurodegeneration: Role of brain innate immune system. CNS & neurological disorders drug targets
Systems biology study of mucopolysaccharidosis using a human metabolic reconstruction network
Salazar, D. A.,Rodriguez-Lopez, A.,Herreno, A.,Barbosa, H.,Herrera, J.,Ardila, A.,Barreto, G. E.,Gonzalez, J.,Almeciga-Diaz, C. J. (2016) Systems biology study of mucopolysaccharidosis using a human metabolic reconstruction network. Mol Genet Metabmol Genet Metab :129-39
Ultrastructural analysis of olfactory ensheathing cells derived from olfactory bulb and nerve of neonatal and juvenile rats
Gomez, R. M.,Ghotme, K.,Botero, L.,Bernal, J. E.,Perez, R.,Barreto, G. E.,Bustos, R. H. (2016) Ultrastructural analysis of olfactory ensheathing cells derived from olfactory bulb and nerve of neonatal and juvenile rats. Neurosci Resneurosci Res :10-7
Neuroinflammation: A Therapeutic Target of Cotinine for the Treatment of Psychiatric Disorders?
Valentina Echeverria;J. Alex Grizzell;George Barreto; (2016) Neuroinflammation: A Therapeutic Target of Cotinine for the Treatment of Psychiatric Disorders?. Current pharmaceutical design
Implication of Green Tea as a Possible Therapeutic Approach for Parkinson Disease
Jurado-Coronel, J. C.,Avila-Rodriguez, M.,Echeverria, V.,Hidalgo, O. A.,Gonzalez, J.,Aliev, G.,Barreto, G. E. (2016) Implication of Green Tea as a Possible Therapeutic Approach for Parkinson Disease. Cns Neurol Disord Drug Targetscns Neurol Disord Drug Targets :292-300
Tibolone protects astrocytic cells from glucose deprivation through a mechanism involving estrogen receptor beta and the upregulation of neuroglobin expression
Avila-Rodriguez, M.,Garcia-Segura, L. M.,Hidalgo-Lanussa, O.,Baez, E.,Gonzalez, J.,Barreto, G. E. (2016) Tibolone protects astrocytic cells from glucose deprivation through a mechanism involving estrogen receptor beta and the upregulation of neuroglobin expression. Mol Cell Endocrinolmol Cell Endocrinol :35-46
Approaches for the Development of Drugs for Treatment of Obesity and Metabolic Syndrome
Maksimov, M. L.,Svistunov, A. A.,Tarasov, V. V.,Chubarev, V. N.,Avila-Rodriguez, M.,Barreto, G. E.,Dralova, O. V.,Aliev, G. (2016) Approaches for the Development of Drugs for Treatment of Obesity and Metabolic Syndrome. Curr Pharm Descurr Pharm Des :895-903
Microglial dependent protective effects of neuroactive steroids
Oscar Lanussa;Marco Ãvila-Rodriguez;Luis GarcÃa-Segura;Janneth González;Valentina Echeverria;Gjumrakch Aliev;George Barreto; (2016) Microglial dependent protective effects of neuroactive steroids. CNS & neurological disorders drug targets
New therapeutic property of dimebon as a neuroprotective agent
Ustyugov, A.;Shevtsova, E.;Barreto, G.E.;Ashraf, G.M.;Bachurin, S.O.;Aliev, G.; (2016) New therapeutic property of dimebon as a neuroprotective agent. Current medicinal chemistry
Unsuspected Intrinsic Property of Melanin to Dissociate Water Can Be Used for the Treatment of CNS Diseases
Herrera, A. S.,del Carmen Arias Esparza, M.,Solis Arias, P. E.,Avila-Rodriguez, M.,Barreto, G. E.,Li, Y.,Bachurin, S. O.,Aliev, G. (2016) Unsuspected Intrinsic Property of Melanin to Dissociate Water Can Be Used for the Treatment of CNS Diseases. Cns Neurol Disord Drug Targetscns Neurol Disord Drug Targets :135-40
Protection by Neuroglobin Expression in Brain Pathologies
Baez, E.,Echeverria, V.,Cabezas, R.,Avila-Rodriguez, M.,Garcia-Segura, L. M.,Barreto, G. E. (2016) Protection by Neuroglobin Expression in Brain Pathologies. Front Neurolfront Neurol :146-
Targeting the Nicotinic Acetylcholine Receptors (nAChRs) in Astrocytes as a Potential Therapeutic Target in Parkinson's Disease
Jurado-Coronel, J. C.,Avila-Rodriguez, M.,Capani, F.,Gonzalez, J.,Moran, V. E.,Barreto, G. E. (2016) Targeting the Nicotinic Acetylcholine Receptors (nAChRs) in Astrocytes as a Potential Therapeutic Target in Parkinson's Disease. Curr Pharm Descurr Pharm Des :1305-11
A synopsis on the linkage between age-related dementias and vascular disorders
Sandesh Chibber;Athanasios Alexiou;Mohammed Alama;George Barreto;Gjumrakch Aliev;Ghulam Ashraf; (2016) A synopsis on the linkage between age-related dementias and vascular disorders. CNS & neurological disorders drug targets
A synopsis on the linkage between age-related dementias and vascular disorders
Chibber, S.,Alexiou, A.,Alama, M. N.,Barreto, G. E.,Aliev, G.,Ashraf, G. M. (2016) A synopsis on the linkage between age-related dementias and vascular disorders. Cns Neurol Disord Drug Targetscns Neurol Disord Drug Targets :250-8
Growth Factors and Astrocytes Metabolism: Possible Roles for Platelet Derived Growth Factor
Cabezas, R.,Avila-Rodriguez, M.,Vega-Vela, N. E.,Echeverria, V.,Gonzalez, J.,Hidalgo, O. A.,Santos, A. B.,Aliev, G.,Barreto, G. E. (2016) Growth Factors and Astrocytes Metabolism: Possible Roles for Platelet Derived Growth Factor. Med Chemmed Chem :204-10
Alterations in Glucose Metabolism on Cognition: A Possible Link Between Diabetes and Dementia
Gonzalez-Reyes, R. E.,Aliev, G.,Avila-Rodrigues, M.,Barreto, G. E. (2016) Alterations in Glucose Metabolism on Cognition: A Possible Link Between Diabetes and Dementia. Curr Pharm Descurr Pharm Des :812-8
A synopsis on the linkage between age-related dementias and vascular disorders
Chibber, S.;Alexiou, A.;Alama, M.N.;Barreto, G.E.;Aliev, G.;Ashraf, G.M.; (2016) A synopsis on the linkage between age-related dementias and vascular disorders. CNS & neurological disorders drug targets
Targeting the nicotinic acetylcholine receptors (nAChRs) in astrocytes as a potential therapeutic target in Parkinsonâs disease
Jurado-Coronel, J.C.;Ãvila-Rodriguez, M.;Capani, F.;Gonzalez, J.;Morán, V.E.;Barreto, G.E.; (2016) Targeting the nicotinic acetylcholine receptors (nAChRs) in astrocytes as a potential therapeutic target in Parkinsonâs disease. Current pharmaceutical design
Meta-analysis of Telomere Length in Alzheimer's Disease
Forero, D. A.,Gonzalez-Giraldo, Y.,Lopez-Quintero, C.,Castro-Vega, L. J.,Barreto, G. E.,Perry, G. (2016) Meta-analysis of Telomere Length in Alzheimer's Disease. J Gerontol A Biol Sci Med Scij Gerontol A Biol Sci Med Sci :1069-73
Updates on the Production of Therapeutic Antibodies Using Human Hybridoma Technique
Glukhova, X. A.,Prusakova, O. V.,Trizna, J. A.,Zaripov, M. M.,Afanas'eva, G. V.,Glukhov, A. S.,Poltavtseva, R. A.,Ivanov, A. A.,Avila-Rodriguez, M.,Barreto, G. E.,Aliev, G.,Beletsky, I. P. (2016) Updates on the Production of Therapeutic Antibodies Using Human Hybridoma Technique. Curr Pharm Descurr Pharm Des :870-8
Implication of Green Tea as a Possible Therapeutic Approach for Parkinson Disease
Juan Jurado-Coronel;Marco Ãvila-Rodriguez;Valentina Echeverria;Oscar Hidalgo;Janneth Gonzalez;Gjumrakch Aliev;George Barreto; (2016) Implication of Green Tea as a Possible Therapeutic Approach for Parkinson Disease. CNS & neurological disorders drug targets
Updates on the production of therapeutic antibodies using human hybridoma technique
Glukhova, X.A.;Prusakova, O.V.;Trizna, J.A.;Zaripov, M.M.;AfanasâEva, G.V.;Glukhov, A.S.;Poltavtseva, R.A.;Ivanov, A.A.;Avila-Rodriguez, M.;Barreto, G.E.;Aliev, G.;Beletsky, I.P.; (2016) Updates on the production of therapeutic antibodies using human hybridoma technique. Current pharmaceutical design
Antifertility activity of lac (Laccifer lacca Kerr.) in female wistar rat model
Perveen, A.;Barreto, G.E.;Jahan, N.;Wadud, A.;Tanwir Alam, M.;Ashraf, G.M.;Aliev, G.; (2016) Antifertility activity of lac (Laccifer lacca Kerr.) in female wistar rat model. Immunology, Endocrine And Metabolic Agents In Medicinal Chemistry
Computational analysis and functional prediction of ubiquitin hypothetical protein: A possible target in parkinson disease
Barragán-Osorio, L.;Giraldo, G.;Alméciga-Diaz, C.J.;Aliev, G.;Barreto, G.E.;Gonzalez, J.; (2016) Computational analysis and functional prediction of ubiquitin hypothetical protein: A possible target in parkinson disease. Central nervous system agents in medicinal chemistry
Telomere length in Parkinson's disease: A meta-analysis
Forero, D. A.,Gonzalez-Giraldo, Y.,Lopez-Quintero, C.,Castro-Vega, L. J.,Barreto, G. E.,Perry, G. (2016) Telomere length in Parkinson's disease: A meta-analysis. Exp Gerontolexp Gerontol :53-5
Neuroinflammation: A Therapeutic Target of Cotinine for the Treatment of Psychiatric Disorders?
Echeverria, V.,Grizzell, J. A.,Barreto, G. E. (2016) Neuroinflammation: A Therapeutic Target of Cotinine for the Treatment of Psychiatric Disorders?. Curr Pharm Descurr Pharm Des :1324-33
Role of Microfluidics in Blood-Brain Barrier Permeability Cell Culture Modeling: Relevance to CNS Disorders
Alexander Rusanov;Natalia Luzgina;George Barreto;Gjumrakch Aliev; (2016) Role of Microfluidics in Blood-Brain Barrier Permeability Cell Culture Modeling: Relevance to CNS Disorders. CNS & neurological disorders drug targets
Neuroinflammation: A therapeutic target of cotinine for the treatment of psychiatric disorders?
Echeverria, V.;Grizzell, J.A.;Barreto, G.E.; (2016) Neuroinflammation: A therapeutic target of cotinine for the treatment of psychiatric disorders?. Current pharmaceutical design
Growth factors and astrocytes metabolism: Possible roles for platelet derived growth factor
Cabezas, R.;Avila-Rodriguez, M.;Vega-Vela, N.E.;Echeverria, V.;González, J.;Hidalgo, O.A.;Santos, A.B.;Aliev, G.;Barreto, G.E.; (2016) Growth factors and astrocytes metabolism: Possible roles for platelet derived growth factor. Journal Of Medicinal Chemistry
Prediction of glycation sites: New insights from protein structural analysis
Sáenz-Suárez, H.;Poutou-Piñales, R.A.;González-Santos, J.;Barreto, G.E.;Rieto-Navarrera, L.P.;Sáenz-Moreno, J.A.;Landázuri, P.;Barrera-Avellaneda, L.A.; (2016) Prediction of glycation sites: New insights from protein structural analysis. Turkish Journal Of Biology
Novel Approaches in Astrocyte Protection: from Experimental Methods to Computational Approaches
Garzon, D.,Cabezas, R.,Vega, N.,Avila-Rodriguez, M.,Gonzalez, J.,Gomez, R. M.,Echeverria, V.,Aliev, G.,Barreto, G. E. (2016) Novel Approaches in Astrocyte Protection: from Experimental Methods to Computational Approaches. J Mol Neuroscij Mol Neurosci :483-92
Testosterone Protects Mitochondrial Function and Regulates Neuroglobin Expression in Astrocytic Cells Exposed to Glucose Deprivation
Toro-Urrego, N.,Garcia-Segura, L. M.,Echeverria, V.,Barreto, G. E. (2016) Testosterone Protects Mitochondrial Function and Regulates Neuroglobin Expression in Astrocytic Cells Exposed to Glucose Deprivation. Front Aging Neuroscifront Aging Neurosci :152-
Approaches for the Development of Drugs for Treatment of Obesity and Metabolic Syndrome
Maksim Maksimov;Andrey Svistunov;Vadim Tarasov;Vladimir Chubarev;Marco Ãvila-Rodriguez;George Barreto;Olga Dralova;Gjumrakch Aliev; (2016) Approaches for the Development of Drugs for Treatment of Obesity and Metabolic Syndrome. Current pharmaceutical design
Unsuspected intrinsic property of melanin to dissociate water can be used for the treatment of CNS diseases
Herrera, A.S.;Esparza, M.C.A.;Arias, P.E.S.;Ãvila-Rodriguez, M.;Barreto, G.E.;Li, Y.;Bachurin, S.O.;Aliev, G.; (2016) Unsuspected intrinsic property of melanin to dissociate water can be used for the treatment of CNS diseases. CNS & neurological disorders drug targets
Computational Analysis and Functional Prediction of Ubiquitin Hypothetical Protein: A Possible Target in Parkinson Disease
Barragan-Osorio, L.,Giraldo, G.,Almeciga-Diaz, C. J.,Aliev, G.,Barreto, G. E.,Gonzalez, J. (2015) Computational Analysis and Functional Prediction of Ubiquitin Hypothetical Protein: A Possible Target in Parkinson Disease. Cent Nerv Syst Agents Med Chemcent Nerv Syst Agents Med Chem :4-11
Nicotine-Derived Compounds as Therapeutic Tools Against Post-Traumatic Stress Disorder
Barreto, G. E.,Yarkov, A.,Avila-Rodriguez, M.,Aliev, G.,Echeverria, V. (2015) Nicotine-Derived Compounds as Therapeutic Tools Against Post-Traumatic Stress Disorder. Curr Pharm Descurr Pharm Des :3589-95
Nutritional and biochemical therapies for neurodegenerative diseases
Salazar Diego;Gonzalez Janneth;Barreto George E.; (2015) Nutritional and biochemical therapies for neurodegenerative diseases. Frontiers In Cellular Neuroscience
Metabolic Reconstruction of Glutamate-Glutamine Cycling: A Flux Balance Approach
Vega-Vela Nelson E.;Jimenez Cynthia;Barreto George E.;Gonzalez Janneth; (2015) Metabolic Reconstruction of Glutamate-Glutamine Cycling: A Flux Balance Approach. Frontiers In Cellular Neuroscience
PDGF-BB protects mitochondria from rotenone in T98G cells
Cabezas, R.,Avila, M. F.,Gonzalez, J.,El-Bacha, R. S.,Barreto, G. E. (2015) PDGF-BB protects mitochondria from rotenone in T98G cells. Neurotox Resneurotox Res :355-67
Nitric Oxide-Dependent Oxidative Stress Induced Mitochondrial DNA Overproliferation and Deletion in the Context of Cancer and Alzheimer Disease
Aliev Gjumrakch;Barreto George E.; (2015) Nitric Oxide-Dependent Oxidative Stress Induced Mitochondrial DNA Overproliferation and Deletion in the Context of Cancer and Alzheimer Disease. Frontiers In Cellular Neuroscience
NMDARs in neurological diseases: a potential therapeutic target
Gonzalez, J.,Jurado-Coronel, J. C.,Avila, M. F.,Sabogal, A.,Capani, F.,Barreto, G. E. (2015) NMDARs in neurological diseases: a potential therapeutic target. Int J Neurosciint J Neurosci :315-27
Nicotine analogues as potential therapeutic agents in Parkinsonâs disease by targeting nicotinic acetylcholine receptors (nAChRs) in astrocytes
Jurado-Coronel Juan;Gonzalez Janneth;Echeverria Moran Valentina;Barreto George E.; (2015) Nicotine analogues as potential therapeutic agents in Parkinsonâs disease by targeting nicotinic acetylcholine receptors (nAChRs) in astrocytes. Frontiers In Cellular Neuroscience
Are sleep disturbances preclinical markers of Parkinson's disease?
dos Santos, A. B.,Kohlmeier, K. A.,Barreto, G. E. (2015) Are sleep disturbances preclinical markers of Parkinson's disease?. Neurochem Resneurochem Res :421-7
The innate immunity in alzheimer disease-relevance to pathogenesis and therapy
Blach-Olszewska, Z.;Zaczynska, E.;Gustaw-Rothenberg, K.;Avila-Rodrigues, M.;Barreto, G.E.;Leszek, J.;Aliev, G.; (2015) The innate immunity in alzheimer disease-relevance to pathogenesis and therapy. Current pharmaceutical design
Implications of astrocytes in mediating the protective effects of Selective Estrogen Receptor Modulators upon brain damage
Martin Cynthia;Gonzalez Janneth;Barreto George E.; (2015) Implications of astrocytes in mediating the protective effects of Selective Estrogen Receptor Modulators upon brain damage. Frontiers In Cellular Neuroscience
Nicotine-derived compounds as therapeutic tools against post-traumatic stress disorder
Barreto, G.E.;Yarkov, A.;Ãvila-Rodriguez, M.;Aliev, G.;Echeverria, V.; (2015) Nicotine-derived compounds as therapeutic tools against post-traumatic stress disorder. Current pharmaceutical design
Neuroprotection by estrogenic compounds following inflammatory insult in the brain
Lanussa Oscar;Ãvila-Rodriguez Marcos;Gonzalez Janneth;Garcia-Segura Luis;Barreto George E.; (2015) Neuroprotection by estrogenic compounds following inflammatory insult in the brain. Frontiers In Cellular Neuroscience
Nicotine-Derived Compounds as Therapeutic Tools Against Post-Traumatic Stress Disorder
George Barreto;Alexander Yarkov;Marcos Avila-Rodriguez;Gjumrakch Aliev;Valentina Echeverria; (2015) Nicotine-Derived Compounds as Therapeutic Tools Against Post-Traumatic Stress Disorder. Current pharmaceutical design
The Innate Immunity in Alzheimer Disease- Relevance to Pathogenesis and Therapy
Zofia Blach-Olszewska;Ewa Zaczynska;Kasia Gustaw-Rothenberg;Marco Avila-Rodrigues;George Barreto;Jerzy Leszek;Gjumrakch Aliev; (2015) The Innate Immunity in Alzheimer Disease- Relevance to Pathogenesis and Therapy. Current pharmaceutical design
Computational brain models: Advances from system biology and future challenges
Gomez Diego;Vega-Vela Nelson;Barreto George E.;Gonzalez Janneth; (2015) Computational brain models: Advances from system biology and future challenges. Frontiers In Cellular Neuroscience
Role of estrogen receptors in the regulation of reactive gliosis
Garcia-Segura Luis;Arevalo Maria Angeles;Azcoitia Inigo;Barreto George E.; (2015) Role of estrogen receptors in the regulation of reactive gliosis. Frontiers In Cellular Neuroscience
Effects of nicotine analogs in an experimental model of Parkinson´s disease: role of CDK5 on dopamine release
Gonzalez Yeimy;Barreto George E.; (2015) Effects of nicotine analogs in an experimental model of Parkinson´s disease: role of CDK5 on dopamine release. Frontiers In Cellular Neuroscience
Editorial on Cerebral endothelial and glial cells are more than bricks in the Great Wall of the brain: insights into the way the blood-brain barrier actually works (celebrating the centenary of Goldman's experiments)
Garcia-Martin, E.,Barreto, G. E.,Agundez, J. A.,Guedes, R. C.,El-Bacha, R. S. (2015) Editorial on Cerebral endothelial and glial cells are more than bricks in the Great Wall of the brain: insights into the way the blood-brain barrier actually works (celebrating the centenary of Goldman's experiments). Front Cell Neuroscifront Cell Neurosci :128-
Nanoparticles as Alternative Strategies for Drug Delivery to the Alzheimer Brain: Electron Microscopy Ultrastructural Analysis
Aliev, G.,Daza, J.,Herrera, A. S.,del Carmen Arias Esparza, M.,Morales, L.,Echeverria, V.,Bachurin, S. O.,Barreto, G. E. (2015) Nanoparticles as Alternative Strategies for Drug Delivery to the Alzheimer Brain: Electron Microscopy Ultrastructural Analysis. Cns Neurol Disord Drug Targetscns Neurol Disord Drug Targets :1235-42
Role of glial cells and neuroactive steroids in traumatic brain injury
Toro Nicolas;Ãvila-Rodriguez Marcos;Garcia-Segura Luis;Barreto George E.; (2015) Role of glial cells and neuroactive steroids in traumatic brain injury. Frontiers In Cellular Neuroscience
Astrocytes mediate the neuroprotective effects of Tibolone following brain injury
Ãvila-Rodriguez Marcos;Garcia-Segura Luis;Barreto George E.; (2015) Astrocytes mediate the neuroprotective effects of Tibolone following brain injury. Frontiers In Cellular Neuroscience
Conjugates of gamma-Carbolines and Phenothiazine as new selective inhibitors of butyrylcholinesterase and blockers of NMDA receptors for Alzheimer Disease
Makhaeva, G. F.,Lushchekina, S. V.,Boltneva, N. P.,Sokolov, V. B.,Grigoriev, V. V.,Serebryakova, O. G.,Vikhareva, E. A.,Aksinenko, A. Y.,Barreto, G. E.,Aliev, G.,Bachurin, S. O. (2015) Conjugates of gamma-Carbolines and Phenothiazine as new selective inhibitors of butyrylcholinesterase and blockers of NMDA receptors for Alzheimer Disease. Sci Repsci Rep :13164-
TIME COURSE MODIFICATIONS INDUCED BY PERINATAL ASPHYXIA IN RAT CNS
Capani Francisco;Kolliker Frers Rodolfo;Barreto George E.;Gonzalez Janneth;Quarracino Cecilia; (2015) TIME COURSE MODIFICATIONS INDUCED BY PERINATAL ASPHYXIA IN RAT CNS. Frontiers In Cellular Neuroscience
Astrocytes as therapeutic targets of estrogenic compounds following brain injuries
Barreto George E.;Aliev Gjumrakch;Garcia-Segura Luis; (2015) Astrocytes as therapeutic targets of estrogenic compounds following brain injuries. Frontiers In Cellular Neuroscience
Mechanisms of PDGFRalpha promiscuity and PDGFRbeta specificity in association with PDGFB
Torrente, D.,Cabezas, R.,Avila, M.,Sanchez, Y.,Morales, L.,Ashraf, G. M.,Barreto, G. E.,Gonzalez, J.,Aliev, G. (2015) Mechanisms of PDGFRalpha promiscuity and PDGFRbeta specificity in association with PDGFB. Front Biosci (Elite Ed)Front Biosci (Elite Ed) :434-46
Antioxidants in Neurodegeneration: Truth or Myth?
Francisco Capani;George Barreto;Eduardo Calvo;Christopher Lillig; (2015) Antioxidants in Neurodegeneration: Truth or Myth?. Antioxidants In Health And Disease
Nanoparticles as alternative strategies for drug delivery to the Alzheimer brain: Electron microscopy ultrastructural analysis
Aliev, G.;Daza, J.;Herrera, A.S.;Esparza, M.D.C.A.;Morales, L.;Echeverria, V.;Bachurin, S.O.;Barreto, G.E.; (2015) Nanoparticles as alternative strategies for drug delivery to the Alzheimer brain: Electron microscopy ultrastructural analysis. CNS & neurological disorders drug targets
Biological Activities of QIAPI 1 as a Melanin Precursor and Its Therapeutic Effects in Wistar Rats Exposed to Arsenic Poisoning
Solis-Herrera, A.,Ashraf, G. M.,del, C. A. Esparza M.,Arias, R. I.,Bachurin, S. O.,Barreto, G. E.,Aliev, G. (2015) Biological Activities of QIAPI 1 as a Melanin Precursor and Its Therapeutic Effects in Wistar Rats Exposed to Arsenic Poisoning. Cent Nerv Syst Agents Med Chemcent Nerv Syst Agents Med Chem :99-108
The Innate Immunity in Alzheimer Disease- Relevance to Pathogenesis and Therapy
Blach-Olszewska, Z.,Zaczynska, E.,Gustaw-Rothenberg, K.,Avila-Rodrigues, M.,Barreto, G. E.,Leszek, J.,Aliev, G. (2015) The Innate Immunity in Alzheimer Disease- Relevance to Pathogenesis and Therapy. Curr Pharm Descurr Pharm Des :3582-8
Novel approaches in astrocytic protection following brain injury
Garzón Daniel;Cabezas Ricardo;Vega Nelson;Ãvila Marcos;González Janneth;Barreto George E.; (2015) Novel approaches in astrocytic protection following brain injury. Frontiers In Cellular Neuroscience
Cotinine prevents memory loss and diminishes Alzheimer's disease-like pathology
Charry Laura;Barreto George E.;Echeverria Moran Valentina; (2015) Cotinine prevents memory loss and diminishes Alzheimer's disease-like pathology. Frontiers In Cellular Neuroscience
Neuroprotective effects of hypothermia on synaptic actin cytoskeletal changes induced by perinatal asphyxia
Muñiz, J.;Romero, J.;Holubiec, M.;Barreto, G.;González, J.;Saint-Martin, M.;Blanco, E.;Carlos Cavicchia, J.;Castilla, R.;Capani, F.; (2014) Neuroprotective effects of hypothermia on synaptic actin cytoskeletal changes induced by perinatal asphyxia. Brain research
Computational Insights of the Interaction among Sea Anemones Neurotoxins and Kv1.3 Channel
Sabogal-Arango, A.,Barreto, G. E.,Ramirez-Sanchez, D.,Gonzalez-Mendoza, J.,Barreto, V.,Morales, L.,Gonzalez, J. (2014) Computational Insights of the Interaction among Sea Anemones Neurotoxins and Kv1.3 Channel. Bioinform Biol Insightsbioinform Biol Insights :73-81
In silico docking reveals possible Riluzole binding sites on Nav1.6 sodium channel: implications for drug design strategy on Amyotrophic Lateral Sclerosis
Sierra Omar;González Janneth;Barreto George; (2014) In silico docking reveals possible Riluzole binding sites on Nav1.6 sodium channel: implications for drug design strategy on Amyotrophic Lateral Sclerosis. Frontiers In Neuroinformatics
Treatment of sleeping disorders should be considered in clinical management of Parkinson's disease
Dos Santos, A. B.,Barreto, G. E.,Kohlmeier, K. A. (2014) Treatment of sleeping disorders should be considered in clinical management of Parkinson's disease. Front Aging Neuroscifront Aging Neurosci :273-
Paracrine factors of human mesenchymal stem cells increase wound closure and reduce reactive oxygen species production in a traumatic brain injury in vitro model
Torrente, D.,Avila, M. F.,Cabezas, R.,Morales, L.,Gonzalez, J.,Samudio, I.,Barreto, G. E. (2014) Paracrine factors of human mesenchymal stem cells increase wound closure and reduce reactive oxygen species production in a traumatic brain injury in vitro model. Hum Exp Toxicolhum Exp Toxicol :673-84
Selective estrogen receptor modulators regulate reactive microglia after penetrating brain injury
Barreto, G. E.,Santos-Galindo, M.,Garcia-Segura, L. M. (2014) Selective estrogen receptor modulators regulate reactive microglia after penetrating brain injury. Front Aging Neuroscifront Aging Neurosci :132-
Tibolone protects T98G cells from glucose deprivation
Avila Rodriguez, M.,Garcia-Segura, L. M.,Cabezas, R.,Torrente, D.,Capani, F.,Gonzalez, J.,Barreto, G. E. (2014) Tibolone protects T98G cells from glucose deprivation. J Steroid Biochem Mol Biolj Steroid Biochem Mol Biol :294-303
Beneficial effects of nicotine, cotinine and its metabolites as potential agents for Parkinson's disease
Barreto, G. E.,Iarkov, A.,Moran, V. E. (2014) Beneficial effects of nicotine, cotinine and its metabolites as potential agents for Parkinson's disease. Front Aging Neuroscifront Aging Neurosci :340-
Dual role of astrocytes in perinatal asphyxia injury and neuroprotection
Romero, J.,Muniz, J.,Logica Tornatore, T.,Holubiec, M.,Gonzalez, J.,Barreto, G. E.,Guelman, L.,Lillig, C. H.,Blanco, E.,Capani, F. (2014) Dual role of astrocytes in perinatal asphyxia injury and neuroprotection. Neurosci Lettneurosci Lett :42-6
Cortical spreading depression and mitochondrial dysfunction with aging: lessons from ethanol abuse
Barreto, G. E.,Capani, F.,Cabezas, R. (2014) Cortical spreading depression and mitochondrial dysfunction with aging: lessons from ethanol abuse. Front Aging Neuroscifront Aging Neurosci :117-
Increased calcium influx triggers and accelerates cortical spreading depression in vivo in male adult rats
Torrente, D.,Mendes-da-Silva, R. F.,Lopes, A. A.,Gonzalez, J.,Barreto, G. E.,Guedes, R. C. (2014) Increased calcium influx triggers and accelerates cortical spreading depression in vivo in male adult rats. Neurosci Lettneurosci Lett :87-90
Protection after stroke: cellular effectors of neurovascular unit integrity
Posada-Duque, R. A.,Barreto, G. E.,Cardona-Gomez, G. P. (2014) Protection after stroke: cellular effectors of neurovascular unit integrity. Front Cell Neuroscifront Cell Neurosci :231-
Computational modeling and preliminary iroN, fepA, and cirA gene expression in Salmonella Enteritidis under iron-deficiency-induced conditions
Zárate-Bonilla, L.J.;Del Portillo, P.;Sáenz-Suárez, H.;Gonzáles-Santos, J.;Barreto-Sampaio, G.E.;Poutou-Piñales, R.A.;Rey, A.F.;Rey, J.G.; (2014) Computational modeling and preliminary iroN, fepA, and cirA gene expression in Salmonella Enteritidis under iron-deficiency-induced conditions. Poultry Science
Cortical spreading depression in traumatic brain injuries: is there a role for astrocytes?
Torrente, D.,Cabezas, R.,Avila, M. F.,Garcia-Segura, L. M.,Barreto, G. E.,Guedes, R. C. (2014) Cortical spreading depression in traumatic brain injuries: is there a role for astrocytes?. Neurosci Lettneurosci Lett :2-6
Structural insights from GRP78-NF-kappaB binding interactions: a computational approach to understand a possible neuroprotective pathway in brain injuries
Avila, M. F.,Torrente, D.,Cabezas, R.,Morales, L.,Garcia-Segura, L. M.,Gonzalez, J.,Barreto, G. E. (2014) Structural insights from GRP78-NF-kappaB binding interactions: a computational approach to understand a possible neuroprotective pathway in brain injuries. J Theor Biolj Theor Biol :43-51
Introduction. Astrocytes in the injured brain: is gliosis adaptive or maladaptive?
Barreto, G. E.,Black, J. A. (2014) Introduction. Astrocytes in the injured brain: is gliosis adaptive or maladaptive?. Neurosci Lettneurosci Lett :1-
Astrocytic modulation of blood brain barrier: perspectives on Parkinson's disease
Cabezas, R.,Avila, M.,Gonzalez, J.,El-Bacha, R. S.,Baez, E.,Garcia-Segura, L. M.,Jurado Coronel, J. C.,Capani, F.,Cardona-Gomez, G. P.,Barreto, G. E. (2014) Astrocytic modulation of blood brain barrier: perspectives on Parkinson's disease. Front Cell Neuroscifront Cell Neurosci :211-
Leishmania braziliensis replication protein A subunit 1: molecular modelling, protein expression and analysis of its affinity for both DNA and RNA
Nocua, P. A.,Ramirez, C. A.,Barreto, G. E.,Gonzalez, J.,Requena, J. M.,Puerta, C. J. (2014) Leishmania braziliensis replication protein A subunit 1: molecular modelling, protein expression and analysis of its affinity for both DNA and RNA. Parasit Vectorsparasit Vectors :573-
Computational insights of the interaction among sea anemones neurotoxins and Kv1.3 channel
Sabogal-Arango, A.;Barreto, G.E.;RamÃrez-Sánchez, D.;González-Mendoza, J.;Barreto, V.;Morales, L.;González, J.; (2014) Computational insights of the interaction among sea anemones neurotoxins and Kv1.3 channel. Bioinformatics And Biology Insights
Using a computational human metabolic reconstruction on the study of mucopolysaccharidosis
Diego Salazar;Alexander RodrÃguez-López;George E. Barreto;Janeth González;Carlos J. Almeciga-Diaz; (2014) Using a computational human metabolic reconstruction on the study of mucopolysaccharidosis. Molecular Genetics And Metabolism
Introduction. Astrocytes in the injured brain: is gliosis adaptive or maladaptive?
Barreto, G.E.;Black, J.A.; (2014) Introduction. Astrocytes in the injured brain: is gliosis adaptive or maladaptive?. Neuroscience Letters
Integrative Approach for Computationally Inferring Interactions between the Alpha and Beta Subunits of the Calcium-Activated Potassium Channel (BK): a Docking Study
Gonzalez, J.,Galvez, A.,Morales, L.,Barreto, G. E.,Capani, F.,Sierra, O.,Torres, Y. (2013) Integrative Approach for Computationally Inferring Interactions between the Alpha and Beta Subunits of the Calcium-Activated Potassium Channel (BK): a Docking Study. Bioinform Biol Insightsbioinform Biol Insights :73-82
Relationship between quality of sleep and cognitive function in patients with parkinson's disease,Relação entre qualidade do sono e funções cognitivas em pacientes com doença de parkinson
Dos Santos, A.B.;Campos, S.L.;Ribeiro, S.;Morales, L.;Gonzalez, J.;Dos Santos Trindade, J.;Barreto, G.E.; (2013) Relationship between quality of sleep and cognitive function in patients with parkinson's disease,Relação entre qualidade do sono e funções cognitivas em pacientes com doença de parkinson. Universitas Scientiarum
Selective activation of protein kinase C in mitochondria is neuroprotective in vitro and reduces focal ischemic brain injury in mice
Sun, X.,Budas, G. R.,Xu, L.,Barreto, G. E.,Mochly-Rosen, D.,Giffard, R. G. (2013) Selective activation of protein kinase C in mitochondria is neuroprotective in vitro and reduces focal ischemic brain injury in mice. J Neurosci Resj Neurosci Res :799-807
Novel interactions of GRP78: UPR and estrogen responses in the brain
Avila, M. F.,Cabezas, R.,Torrente, D.,Gonzalez, J.,Morales, L.,Alvarez, L.,Capani, F.,Barreto, G. E. (2013) Novel interactions of GRP78: UPR and estrogen responses in the brain. Cell Biol Intcell Biol Int :521-32
In silico insights of L-glutamate: structural features in vacuum and in complex with its receptor
Gonzalez, J.,Barreto, G. E. (2013) In silico insights of L-glutamate: structural features in vacuum and in complex with its receptor. J Amino Acidsj Amino Acids :872058-
Polyphenols and neurodegenerative diseases
Barreto, G. E.,Guedes, R. C. (2012) Polyphenols and neurodegenerative diseases. Nutr Neuroscinutr Neurosci :92-3
Protein LIC10494 of Leptospira interrogans serovar Copenhageni: Structural model and associated functional regions,ProteÃna LIC10494 de Leptospira interrogans serovar Copenhageni: Modelo estructural y regiones funcionales asociadas
Barreto, L.V.;Barreto, G.E.;Morales, L.;Acevedo, O.E.;Santos, J.G.; (2012) Protein LIC10494 of Leptospira interrogans serovar Copenhageni: Structural model and associated functional regions,ProteÃna LIC10494 de Leptospira interrogans serovar Copenhageni: Modelo estructural y regiones funcionales asociadas. Universitas Scientiarum
Effects of natural antioxidants in neurodegenerative disease
Albarracin, S. L.,Stab, B.,Casas, Z.,Sutachan, J. J.,Samudio, I.,Gonzalez, J.,Gonzalo, L.,Capani, F.,Morales, L.,Barreto, G. E. (2012) Effects of natural antioxidants in neurodegenerative disease. Nutr Neuroscinutr Neurosci :1-9
ProteÃna LIC10494 de Leptospira interrogans serovar Copenhageni: modelo estructural y regiones funcionales asociadas
Leidy Viviana Barreto;George EmÃlio Barreto;Ludis Morales;Orlando Emilio Acevedo;Janneth González Santos; (2012) ProteÃna LIC10494 de Leptospira interrogans serovar Copenhageni: modelo estructural y regiones funcionales asociadas. Universitas Scientiarum
Neuroprotective agents in brain injury: a partial failure?
Barreto, G. E.,Gonzalez, J.,Capani, F.,Morales, L. (2012) Neuroprotective agents in brain injury: a partial failure?. Int J Neurosciint J Neurosci :223-6
Mitochondrial functions in astrocytes: neuroprotective implications from oxidative damage by rotenone
Cabezas, R.,El-Bacha, R. S.,Gonzalez, J.,Barreto, G. E. (2012) Mitochondrial functions in astrocytes: neuroprotective implications from oxidative damage by rotenone. Neurosci Resneurosci Res :80-90
Effects of heat shock protein 72 (Hsp72) on evolution of astrocyte activation following stroke in the mouse
Barreto, G. E.,White, R. E.,Xu, L.,Palm, C. J.,Giffard, R. G. (2012) Effects of heat shock protein 72 (Hsp72) on evolution of astrocyte activation following stroke in the mouse. Exp Neurolexp Neurol :284-96
Effects of perinatal asphyxia on rat striatal cytoskeleton
Saraceno, G.E.;Ayala, M.V.;Badorrey, M.S.;Holubiec, M.;Romero, J.I.;Galeano, P.;Barreto, G.;Giraldez-Alvárez, L.D.;Kölliker-fres, R.;Coirini, H.;Capani, F.; (2012) Effects of perinatal asphyxia on rat striatal cytoskeleton. Synapse
Hippocampal dendritic spines modifications induced by perinatal asphyxia
Saraceno, G. E.,Castilla, R.,Barreto, G. E.,Gonzalez, J.,Kolliker-Frers, R. A.,Capani, F. (2012) Hippocampal dendritic spines modifications induced by perinatal asphyxia. Neural Plastneural Plast :873532-
Early changes in the synapses of the neostriatum induced by perinatal asphyxia
Grimaldi, M.;Romer, I.;González de Apodaca, M.T.;Iturbe, L.;Catania, I.D.;González, J.;Kolliker-Fres, R.;Barreto, G.;Capani, F.; (2012) Early changes in the synapses of the neostriatum induced by perinatal asphyxia. Nutritional Neuroscience
In silico docking reveals possible Riluzole binding sites on Nav1.6 sodium channel: implications for amyotrophic lateral sclerosis therapy
Sierra Bello, O.,Gonzalez, J.,Capani, F.,Barreto, G. E. (2012) In silico docking reveals possible Riluzole binding sites on Nav1.6 sodium channel: implications for amyotrophic lateral sclerosis therapy. J Theor Biolj Theor Biol :53-63
Neuroprotection from stroke in the absence of MHCI or PirB
Adelson, J. D.,Barreto, G. E.,Xu, L.,Kim, T.,Brott, B. K.,Ouyang, Y. B.,Naserke, T.,Djurisic, M.,Xiong, X.,Shatz, C. J.,Giffard, R. G. (2012) Neuroprotection from stroke in the absence of MHCI or PirB. Neuronneuron :1100-7
Cellular and molecular mechanisms of antioxidants in Parkinson's disease
Sutachan, J. J.,Casas, Z.,Albarracin, S. L.,Stab, B. R., 2nd,Samudio, I.,Gonzalez, J.,Morales, L.,Barreto, G. E. (2012) Cellular and molecular mechanisms of antioxidants in Parkinson's disease. Nutr Neuroscinutr Neurosci :120-6
Astrocytes: targets for neuroprotection in stroke
Barreto, G.,White, R. E.,Ouyang, Y.,Xu, L.,Giffard, R. G. (2011) Astrocytes: targets for neuroprotection in stroke. Cent Nerv Syst Agents Med Chemcent Nerv Syst Agents Med Chem :164-73
Neuroprotection by estradiol: some important considerations
Barreto, G. E. (2011) Neuroprotection by estradiol: some important considerations. Hum Exp Toxicolhum Exp Toxicol :1737-9
Astrocyte proliferation following stroke in the mouse depends on distance from the infarct
Barreto, G. E.,Sun, X.,Xu, L.,Giffard, R. G. (2011) Astrocyte proliferation following stroke in the mouse depends on distance from the infarct. Plos Oneplos One
Astrocytic-neuronal crosstalk: implications for neuroprotection from brain injury
Barreto, G. E.,Gonzalez, J.,Torres, Y.,Morales, L. (2011) Astrocytic-neuronal crosstalk: implications for neuroprotection from brain injury. Neurosci Resneurosci Res :107-13
Astrocytes: Targets for neuroprotection in stroke
Barreto, G.;White, R.E.;Ouyang, Y.;Xu, L.;Giffard, R.G.; (2011) Astrocytes: Targets for neuroprotection in stroke. Central nervous system agents in medicinal chemistry
Long-lasting effects of perinatal asphyxia on exploration, memory and incentive downshift
Galeano, P.,Blanco Calvo, E.,Madureira de Oliveira, D.,Cuenya, L.,Kamenetzky, G. V.,Mustaca, A. E.,Barreto, G. E.,Giraldez-Alvarez, L. D.,Milei, J.,Capani, F. (2011) Long-lasting effects of perinatal asphyxia on exploration, memory and incentive downshift. Int J Dev Neurosciint J Dev Neurosci :609-19
Astrocytes: Targets for Neuroprotection in Stroke
George Barreto;Robin E. White;Yibing Ouyang;Lijun Xu;Rona G. Giffard; (2011) Astrocytes: Targets for Neuroprotection in Stroke. Central nervous system agents in medicinal chemistry
Heat shock protein 72 overexpression prevents early postoperative memory decline after orthopedic surgery under general anesthesia in mice
Vizcaychipi, M. P.,Xu, L.,Barreto, G. E.,Ma, D.,Maze, M.,Giffard, R. G. (2011) Heat shock protein 72 overexpression prevents early postoperative memory decline after orthopedic surgery under general anesthesia in mice. Anesthesiologyanesthesiology :891-900
Paullinia cupana Mart. var. Sorbilis protects human dopaminergic neuroblastoma SH-SY5Y cell line against rotenone-induced cytotoxicity
De Oliveira, D.M.;Barreto, G.;Galeano, P.;Romero, J.I.;Holubiec, M.I.;Badorrey, M.S.;Capani, F.;Giraldez Alvarez, L.D.; (2011) Paullinia cupana Mart. var. Sorbilis protects human dopaminergic neuroblastoma SH-SY5Y cell line against rotenone-induced cytotoxicity. Human & Experimental Toxicology
Increased brain injury and worsened neurological outcome in interleukin-4 knockout mice after transient focal cerebral ischemia
Xiong, X.,Barreto, G. E.,Xu, L.,Ouyang, Y. B.,Xie, X.,Giffard, R. G. (2011) Increased brain injury and worsened neurological outcome in interleukin-4 knockout mice after transient focal cerebral ischemia. Strokestroke :2026-32
Heat shock protein 72 (Hsp72) improves long term recovery after focal cerebral ischemia in mice
Xu, L.;Xiong, X.;Ouyang, Y.;Barreto, G.;Giffard, R.; (2011) Heat shock protein 72 (Hsp72) improves long term recovery after focal cerebral ischemia in mice. Neuroscience Letters
Age-related defects in sensorimotor activity, spatial learning, and memory in C57BL/6 mice
Barreto, G.,Huang, T. T.,Giffard, R. G. (2010) Age-related defects in sensorimotor activity, spatial learning, and memory in C57BL/6 mice. J Neurosurg Anesthesiolj Neurosurg Anesthesiol :214-9
Protein ubiquitination in postsynaptic densities after hypoxia in rat neostriatum is blocked by hypothermia
Capani, F.;Saraceno, G.E.;Botti, V.;Aon-Bertolino, L.;Madureira de Oliveira, D.;Barreto, G.;Galeano, P.;Giraldez-Alvarez, L.D.;Coirini, H.; (2009) Protein ubiquitination in postsynaptic densities after hypoxia in rat neostriatum is blocked by hypothermia. Experimental Neurology
The role of catechols and free radicals in benzene toxicity: An oxidative DNA damage pathway
Barreto, G.;Madureira, D.;Capani, F.;Aon-Bertolino, L.;Saraceno, E.;Alvarez-Giraldez, L.D.; (2009) The role of catechols and free radicals in benzene toxicity: An oxidative DNA damage pathway. Environmental And Molecular Mutagenesis
Selective estrogen receptor modulators decrease reactive astrogliosis in the injured brain: effects of aging and prolonged depletion of ovarian hormones
Barreto, G.,Santos-Galindo, M.,Diz-Chaves, Y.,Pernia, O.,Carrero, P.,Azcoitia, I.,Garcia-Segura, L. M. (2009) Selective estrogen receptor modulators decrease reactive astrogliosis in the injured brain: effects of aging and prolonged depletion of ovarian hormones. Endocrinologyendocrinology :5010-5
Cytoprotective effect of valeriana officinalis extract on an in vitro experimental model of parkinson disease
De Oliveria, D.M.;Barreto, G.;De Andrade, D.V.G.;Saraceno, E.;Aon-Bertolino, L.;Capani, F.;Dos Santos El Bachá, R.;Giraldez, L.D.; (2009) Cytoprotective effect of valeriana officinalis extract on an in vitro experimental model of parkinson disease. Neurochemical Research
Effects of the extract of Anemopaegma mirandum (Catuaba) on Rotenone-induced apoptosis in human neuroblastomas SH-SY5Y cells
De Andrade, D.V.G.;Madureira de Oliveria, D.;Barreto, G.;Bertolino, L.-A.;Saraceno, E.;Capani, F.;Giraldez, L.D.; (2008) Effects of the extract of Anemopaegma mirandum (Catuaba) on Rotenone-induced apoptosis in human neuroblastomas SH-SY5Y cells. Brain research
Investigation of toxic factors affecting cells of rat brains exposed to 3-methylcatechol
Barreto, G.E.S.;De Oliveira, E.S.;De Villar, F.A.G.A.;Dos Santos, G.S.;Lima, R.M.F.;Costa, S.L.;Costa, M.D.F.D.;Egito, E.S.T.;El-Bachá, R.S.; (2007) Investigation of toxic factors affecting cells of rat brains exposed to 3-methylcatechol. Brazilian Archives Of Biology And Technology
Testosterone decreases reactive astroglia and reactive microglia after brain injury in male rats: role of its metabolites, oestradiol and dihydrotestosterone
Barreto, G.,Veiga, S.,Azcoitia, I.,Garcia-Segura, L. M.,Garcia-Ovejero, D. (2007) Testosterone decreases reactive astroglia and reactive microglia after brain injury in male rats: role of its metabolites, oestradiol and dihydrotestosterone. Eur J Neuroscieur J Neurosci :3039-46
Catechol inhibits FADH2-linked respiration in rat liver mitochondrial fraction.
Barreto, G.E.;dos Santos, G.S.;Egito, E.S.;El-Bachá, R.S.; (2005) Catechol inhibits FADH2-linked respiration in rat liver mitochondrial fraction.. Acta CirãºRgica Brasileira / Sociedade Brasileira Para Desenvolvimento Pesquisa Em Cirurgia
Catechol inhibits FADH2-linked respiration in rat liver mitochondrial fraction
Barreto, G. E.,dos Santos, G. S.,Egito, E. S.,El-Bacha Rdos, S. (2005) Catechol inhibits FADH2-linked respiration in rat liver mitochondrial fraction. Acta Cir Brasacta Cir Bras :72-7
Books
Neuroprotection by Exogenous Estrogenic Compounds Following Traumatic Brain Injury
Lopez-Rodriguez, A.B.;Ãvila-Rodriguez, M.;Vega-Vela, N.E.;Capani, F.;Gonzalez, J.;GarcÃa-Segura, L.M.;Barreto, G.E.; (2015) Neuroprotection by Exogenous Estrogenic Compounds Following Traumatic Brain Injury. Estrogen Effects on Traumatic Brain Injury: Mechanisms of Neuroprotection and Repair
Neuroprotection with Estradiol in Experimental Perinatal Asphyxia: A New Approach. A New Approach.
Barreto, G.;Saraceno, E.;Gonzalez, J.;Kolliker, R.;Castilla, R.;Capani, F.; (2015) Neuroprotection with Estradiol in Experimental Perinatal Asphyxia: A New Approach. A New Approach.. Estrogen Effects on Traumatic Brain Injury: Mechanisms of Neuroprotection and Repair
Antioxidants in neurodegeneration: Truth or myth?
Capani, F.;Barreto, G.;Calvo, E.B.;Lillig, C.H.; (2015) Antioxidants in neurodegeneration: Truth or myth?. Antioxidants In Health And Disease
Analysis of binding residues between PDGF-BB and epidermal growth factor receptor: A computational docking study
Cabezas, R.;Torrente, D.;Avila, M.F.;González, J.;Barreto, G.E.; (2014) Analysis of binding residues between PDGF-BB and epidermal growth factor receptor: A computational docking study. Advances in Intelligent Systems and Computing
In silico analysis of iduronate 2 sulfatase mutations in Colombian patients with Hunter Syndrome (MPSII)
Galvis, J.;González, J.;Torrente, D.;Velasco, H.;Barreto, G.E.; (2014) In silico analysis of iduronate 2 sulfatase mutations in Colombian patients with Hunter Syndrome (MPSII). Advances in Intelligent Systems and Computing
Structural and functional prediction of the hypothetical protein PA2481 in Pseudomonas aeruginosa Pao1
DÃaz, D.A.;Barreto, G.E.;Santos, J.G.; (2014) Structural and functional prediction of the hypothetical protein PA2481 in Pseudomonas aeruginosa Pao1. Advances in Intelligent Systems and Computing
Natural Antioxidants in Dementia: An Overview
Cabezas, R.;Fidel Avila, M.;Torrente, D.;Gonzalez, J.;Santos El-Bachá, R.;Guedes, R.;Barreto, G.E.; (2014) Natural Antioxidants in Dementia: An Overview. Diet and Nutrition in Dementia and Cognitive Decline
Regulación por andrógenos y estrógenos de la gliosis tras lesiones cerebrales en la rata
George E. Barreto (2009) Regulación por andrógenos y estrógenos de la gliosis tras lesiones cerebrales en la rata. Madrid, Spain : Universidad Complutense de Madrid
Estudo do efecto dos metabolitos do benzeno e tolueno sobre as mitocondrias cerebrais e hepáticas de ratos
George Barreto (2005) Estudo do efecto dos metabolitos do benzeno e tolueno sobre as mitocondrias cerebrais e hepáticas de ratos. Natal, Brazil : Universidade Federal de Rio Grande de Norte
Book Chapters
Mitochondrial KATP Channel and Dopaminergic Vulnerability Neurons in Parkinson's Disease
Gesivaldo Santos, Julita Maria Pereira Borges, Marcos Avilla-Rodriguez, Érika Pereira Rubio, Cattiúscia Batista Bromochenkel, Djalma Menezes Oliveira, Jane Lima dos Santos, Rosane Moura Aguiar, Milena Mascarenhas Ferraz, Silvana Batista Gaino, Francisco Capani and George E Barreto (2019) Mitochondrial KATP Channel and Dopaminergic Vulnerability Neurons in Parkinson's Disease. Croatia : IntechOpen Parkinson's Disease and Beyond - A Neurocognitive Approach
Neuroprotection with estradiol in experimental perinatal asphyxia: a new approach
George Barreto, Ezequiel Saraceno, Janneth González, Rodolfo Kolliker, Rocío Castilla, Francisco Capani (2014) Neuroprotection with estradiol in experimental perinatal asphyxia: a new approach. Ireland : Elsevier Estrogen Effects on Traumatic Brain Injury
Neuroprotection by exogenous estrogenic compounds following traumatic brain injury
Ana Belen Lopez-Rodriguez, Marco Ávila-Rodriguez, Nelson E Vega-Vela, Francisco Capani, Janneth Gonzalez, Luis Miguel García-Segura, George E. Barreto (2014) Neuroprotection by exogenous estrogenic compounds following traumatic brain injury. Ireland : Elsevier Estrogen Effects on Traumatic Brain Injury
Natural antioxidants in dementia: an overview
Ricardo Cabezas, Marco Fidel Avila, Daniel Torrente, Janneth Gonzalez, Ramon Santos El-Bacha, Rubem Guedes, George E. Barreto (2014) Natural antioxidants in dementia: an overview. Ireland : Academic Press (Elsevier) Diet and Nutrition in Dementia and cognitive decline series book
Analysis of Binding Residues between PDGF-BB and Epidermal Growth Factor Receptor: A Computational Docking Study
Ricardo Cabezas, Daniel Torrente, Marcos Avila, Janneth Gonzalez, George E. Barreto (2013) Analysis of Binding Residues between PDGF-BB and Epidermal Growth Factor Receptor: A Computational Docking Study. Colombia : Springer 2nd Congress on Computational Biology and Bioinformatics
Structural and functional prediction of the hypothetical protein PA2481
David Diaz, George E. Barreto, Janneth González (2013) Structural and functional prediction of the hypothetical protein PA2481. Colombia : Springer 2nd Congress on Computational Biology and Bioinformatics
Role of astrocytes in Parkinson: A double edged-sword
Ricardo Cabezas, Marco Fidel, Ramon El-Bachá, Janneth Gonzalez, Ludis Morales, George E. Barreto (2013) Role of astrocytes in Parkinson: A double edged-sword. Croatia : Intech Neurodegenerative Diseases
In silico Analysis of Iduronate 2 Sulfatase Mutations in Colombian Patients with Hunter Syndrome
Johanna Galvis, Janneth González, Daniel Torrente, Harvy Velasco, George E. Barreto (2013) In silico Analysis of Iduronate 2 Sulfatase Mutations in Colombian Patients with Hunter Syndrome. Colombia : Springer 2nd Congress on Computational Biology and Bioinformatics
Role of astrocytes in Neurodegenerative diseases
George E. Barreto, Janneth González, Francisco Capani, Ludis Morales (2011) Role of astrocytes in Neurodegenerative diseases. Croatia : InTech Neurodegenerative Diseases
Edited Books
Editorial on Cerebral endothelial and glial cells are more than bricks in the Great Wall of the brain: insights into the way the blood-brain barrier actually works (celebrating the centenary of Goldman's experiments).
(2015) Editorial on Cerebral endothelial and glial cells are more than bricks in the Great Wall of the brain: insights into the way the blood-brain barrier actually works (celebrating the centenary of Goldman's experiments).. Lausanne : Frontiers in Cellular Neuroscience
Other Journals
Conference Publications
Conference Contributions
Published Reports
Editorials
Current Trends for Rationalizing Brain Targeting Nanoparticles in Neurological Disorders (Part-I).
Javed MN;Ashraf GM;Barreto GE;Naim MJ; (2020) Current Trends for Rationalizing Brain Targeting Nanoparticles in Neurological Disorders (Part-I).. Current Drug Metabolism
Neuroproteomics on the Rise (Part I).
Uddin MS;Athanasios A;Barreto GE;Ashraf GM; (2020) Neuroproteomics on the Rise (Part I).. Current Protein & Peptide Science
Book Reviews
Other Publications
Current Trends for Rationalizing Brain Targeting Nanoparticles in Neurological Disorders (Part-I).
Javed MN;Ashraf GM;Barreto GE;Naim MJ; (2020) Current Trends for Rationalizing Brain Targeting Nanoparticles in Neurological Disorders (Part-I).. Current Drug Metabolism
Neuroproteomics on the Rise (Part I).
Uddin MS;Athanasios A;Barreto GE;Ashraf GM; (2020) Neuroproteomics on the Rise (Part I).. Current Protein & Peptide Science