Dr. Elizabeth Ryan

Alana Nash;Elizabeth J. Ryan; (2022) The oncogenic gamma herpesviruses Epstein-Barr virus (EBV) and Kaposi's sarcoma-associated herpesvirus (KSHV) hijack retinoic acid-inducible gene I (RIG-I) facilitating both viral and tumour immune evasion. Tumour Virus Research

Hannah K. Fitzgerald;Sinead A. O’Rourke;Eva Desmond;Nuno G. B. Neto;Michael G. Monaghan;Miriam Tosetto;Jayne Doherty;Elizabeth J. Ryan;Glen A. Doherty;Derek P. Nolan;Jean M. Fletcher;Aisling Dunne; (2022) The Trypanosoma brucei-Derived Ketoacids, Indole Pyruvate and Hydroxyphenylpyruvate, Induce HO-1 Expression and Suppress Inflammatory Responses in Human Dendritic Cells. Antioxidants

Doherty J.;Morain N.O.;Stack R.;Girod P.;Tosetto M.;Inzitiari R.;Sheridan J.;Cullen G.;McDermott E.;Buckley M.;Horgan G.;Mulcahy H.;Ryan E.J.;Daghfal D.;Doran P.;Morain C.O.;Doherty G.A. (2022) Reduced Serological Response to COVID-19 Vaccines in Patients with IBD is Further Diminished by TNF Inhibitor Therapy; Early Results of the VARIATION study [VAriability in Response in IBD Against SARS-COV-2 ImmunisatiON. Journal Of Crohns &Amp; Colitis :1354-1362

Zamboni F.;Ren G.;Culebras M.;O'Driscoll J.;O'Dwyer J.;Ryan E.J.;Collins M.N. (2022) Curcumin encapsulated polylactic acid nanoparticles embedded in alginate/gelatin bioinks for in situ immunoregulation: Characterization and biological assessment. International Journal Of Biological Macromolecules :1218-1227

Zaiatz Bittencourt V;Jones F;Tosetto M;Doherty GA;Ryan EJ; (2021) Dysregulation of metabolic pathways in circulating natural killer cells isolated from inflammatory bowel disease patients.. Journal Of Crohns &Amp; Colitis

(2021) Review Article: Vaccination for patients with inflammatory bowel disease during the COVID-19 pandemic.. Alimentary Pharmacology & Therapeutics

Whitmore, L;Yetsko, K;Farrell, JA;Page-Karjian, A;Daniel, W;Shaver, DJ;Frandsen, HR;Walker, JS;Crowder, W;Bovery, C;Ramia, DR;Burkhalter, B;Ryan, E;Duffy, DJ (2021) Evolutionary Comparisons of Chelonid Alphaherpesvirus 5 (ChHV5) Genomes from Fibropapillomatosis-Afflicted Green (Chelonia mydas), Olive Ridley (Lepidochelys olivacea) and Kemp's Ridley (Lepidochelys kempii) Sea Turtles. BASEL : MDPI Animals

Zaiatz Bittencourt V;Jones F;Doherty G;Ryan EJ; (2021) Targeting Immune Cell Metabolism in the Treatment of Inflammatory Bowel Disease.. Inflammatory bowel diseases

O'Callaghan ME;Ryan E;Walsh C;Hayes P;Casey M;O'Dwyer P;Culhane A;Duncan JW;Harrold P;Healy J;Kerin E;Kelly E;Hanrahan C;Lane GP;Lynch B;Meaney P;O'Connell B;Galvin J;Kennedy N;Burke P;O'Connell NH;Dunne CP;Glynn LG; (2021) Seroprevalence study of SARS-CoV-2 infection in General Practice in Ireland.. Bjgp Open

(2020) Characteristics and attitudes of first round invitees in the Irish National Colorectal Cancer Screening Programme. Frontline Gastroenterology

Zamboni F.;Ryan E.;Culebras M.;Collins M.N. (2020) Labile crosslinked hyaluronic acid via urethane formation using bis(β-isocyanatoethyl) disulphide with tuneable physicochemical and immunomodulatory properties. Carbohydrate Polymers

Roseweir AK;Park JH;Hoorn ST;Powell AG;Aherne S;Roxburgh CS;McMillan DC;Horgan PG;Ryan E;Sheahan K;Vermeulen L;Paul J;Harkin A;Graham J;Sansom O;Church DN;Tomlinson I;Saunders M;Iveson TJ;Edwards J; (2020) Histological phenotypic subtypes predict recurrence risk and response to adjuvant chemotherapy in patients with stage III colorectal cancer.. The Journal Of Pathology. Clinical Research

Morrissey ME;Byrne R;Nulty C;McCabe NH;Lynam-Lennon N;Butler CT;Kennedy S;O'Toole D;Larkin J;McCormick P;Mehigan B;Cathcart MC;Lysaght J;Reynolds JV;Ryan EJ;Dunne MR;O'Sullivan J; (2020) The tumour microenvironment of the upper and lower gastrointestinal tract differentially influences dendritic cell maturation.. Bmc Cancer

Dunne M.R.;Phelan J.J.;Michielsen A.J.;Maguire A.A.;Dunne C.;Martin P.;Noonan S.;Tosetto M.;Geraghty R.;Fennelly D.;Sheahan K.;Ryan E.J.;O’Sullivan J. (2020) Characterising the prognostic potential of HLA-DR during colorectal cancer development. Cancer Immunology Immunotherapy

Thomas V.;Cotter M.B.;Tosetto M.;Khaw Y.L.;Geraghty R.;Winter D.C.;Ryan E.J.;Sheahan K.;Furney S.J. (2020) Personalised mapping of tumour development in synchronous colorectal cancer patients. Npj Genomic Medicine

Caiazza F;Oficjalska K;Tosetto M;Phelan JJ;Noonan S;Martin P;Killick K;Breen L;O'Neill F;Nolan B;Furney S;Power R;Fennelly D;Craik CS;O'Sullivan J;Sheahan K;Doherty GA;Ryan EJ; (2019) KH-Type Splicing Regulatory Protein Controls Colorectal Cancer Cell Growth and Modulates the Tumor Microenvironment.. The American journal of pathology

McCarthy AJ;O'Reilly SM;Shanley J;Geraghty R;Ryan EJ;Cullen G;Sheahan K; (2019) Colorectal Serrated Neoplasia: An Institutional 12-Year Review Highlights the Impact of a Screening Programme.. Gastroenterology Research And Practice

Rowan CR;Cullen G;Mulcahy HE;Sheridan J;Moss AC;Ryan EJ;Doherty GA; (2019) DUBLIN (Degree of Ulcerative colitis Burden of Luminal INflammation) score, a simple method to quantify inflammatory burden in Ulcerative Colitis.. Journal Of Crohns &Amp; Colitis

Amodio G;Cichy J;Conde P;Matteoli G;Moreau A;Ochando J;Oral BH;Pekarova M;Ryan EJ;Roth J;Sohrabi Y;Cuturi MC;Gregori S; (2019) Role of myeloid regulatory cells (MRCs) in maintaining tissue homeostasis and promoting tolerance in autoimmunity, inflammatory disease and transplantation.. Cancer Immunology Immunotherapy

Lindner A.;Resler A.;Carberry S.;Oficjalska K.;Bacon O.;Lee C.;Choudhry A.;Burke J.;Sheahan K.;Cremona M.;Hennessy B.;McNamara D.;Doherty G.;Ryan E.;Prehn J. (2019) Systems biology analysis identifies molecular determinants of chemotherapy-induced diarrhoea. Molecular Medicine

Hand F;Ryan EJ;Harrington C;Durand M;Maguire D;O'Farrelly C;Hoti E;Geoghegan JG; (2019) Chemotherapy and repeat resection abrogate the prognostic value of neutrophil lymphocyte ratio in colorectal liver metastases.. Hpb : The Official Journal Of The International Hepato Pancreato Biliary Association

Kelly ME;Mohan HM;Baird AW;Ryan EJ;Winter DC; (2018) Orphan Nuclear Receptors in Colorectal Cancer.. Pathology oncology research : POR

Ryan É;Khaw YL;Creavin B;Geraghty R;Ryan EJ;Gibbons D;Hanly A;Martin ST;O'Connell PR;Winter DC;Sheahan K; (2018) Tumor Budding and PDC Grade Are Stage Independent Predictors of Clinical Outcome in Mismatch Repair Deficient Colorectal Cancer.. American Journal Of Surgical Pathology

(2018) Transcriptional subtyping and CD8 immunohistochemistry identifies poor prognosis stage II/III colorectal cancer patients who benefit from adjuvant chemotherapy. Jco Precision Oncology

Hand F;Harmon C;Elliott LA;Caiazza F;Lavelle A;Maguire D;Hoti E;Nolan N;Geoghegan JG;Ryan EJ;O'Farrelly C; (2018) Depleted polymorphonuclear leukocytes in human metastatic liver reflect an altered immune microenvironment associated with recurrent metastasis.. Cancer Immunology Immunotherapy

(2018) Severe Symptomatic Primary CMV Infection in Inflammatory Bowel Disease Patients with Low Population Seroprevalence. Gastroenterology Research And Practice

Ryan ÉJ;Creavin B;Khaw YL;Kelly ME;Mohan HM;Geraghty R;Ryan EJ;Kennelly R;Hanly A;Martin ST;Fennelly D;McDermott R;Gibbons D;O'Connell PR;Sheahan K;Winter DC; (2018) Effects of CDX2 on prognosis and chemotherapy responsiveness in mismatch repair-deficient colorectal cancer.. Bjs Open

Ryan É;Khaw YL;Creavin B;Geraghty R;Ryan EJ;Gibbons D;Hanly A;Martin ST;O'Connell PR;Winter DC;Sheahan K; (2018) Tumor Budding and PDC Grade Are Stage Independent Predictors of Clinical Outcome in Mismatch Repair Deficient Colorectal Cancer.. American Journal Of Surgical Pathology

Rowan CR;Keegan D;Byrne K;Cullen G;Mulcahy HE;Sheridan J;Ryan EJ;de Vries A;D'Haens G;Doherty GA; (2018) Subcutaneous rather than intravenous ustekinumab induction is associated with comparable circulating drug levels and early clinical response: a pilot study.. Alimentary Pharmacology &Amp; Therapeutics

Dunne MR;Michielsen AJ;O'Sullivan KE;Cathcart MC;Feighery R;Doyle B;Watson JA;O'Farrell NJ;Ravi N;Kay E;Reynolds JV;Ryan EJ;O'Sullivan J; (2017) HLA-DR expression in tumor epithelium is an independent prognostic indicator in esophageal adenocarcinoma patients.. Cancer Immunology Immunotherapy

Elliott LA;Doherty GA;Sheahan K;Ryan EJ; (2017) Human Tumor-Infiltrating Myeloid Cells: Phenotypic and Functional Diversity.. Frontiers In Immunology

Mohan HM;Ryan E;Balasubramanian I;Kennelly R;Geraghty R;Sclafani F;Fennelly D;McDermott R;Ryan EJ;O'Donoghue D;Hyland JM;Martin ST;O'Connell PR;Gibbons D;Winter D;Sheahan K; (2016) Microsatellite instability is associated with reduced disease specific survival in stage III colon cancer.. European Journal Of Surgical Oncology : The Journal Of The European Society Of Surgical Oncology And The British Association Of Surgical Oncology

Kelly A;Robinson MW;Roche G;Biron CA;O'Farrelly C;Ryan EJ; (2016) Immune Cell Profiling of IFN-λ Response Shows pDCs Express Highest Level of IFN-λR1 and Are Directly Responsive Via the JAK-STAT Pathway..

Caiazza F;Murray A;Madden SF;Synnott NC;Ryan EJ;O'Donovan N;Crown J;Duffy MJ; (2016) Preclinical evaluation of the AR inhibitor enzalutamide in triple-negative breast cancer cells..

Caiazza F;Murray A;Madden SF;Synnott NC;Ryan EJ;O'Donovan N;Crown J;Duffy MJ; (2016) Preclinical evaluation of the AR inhibitor enzalutamide in triple-negative breast cancer cells.. Endocrine-Related Cancer

McDermott E;Ryan EJ;Tosetto M;Gibson D;Burrage J;Keegan D;Byrne K;Crowe E;Sexton G;Malone K;Harris RA;Kellermayer R;Mill J;Cullen G;Doherty GA;Mulcahy H;Murphy TM; (2016) DNA Methylation Profiling in Inflammatory Bowel Disease Provides New Insights into Disease Pathogenesis.. Journal Of Crohns &Amp; Colitis

Kelly A;Robinson MW;Roche G;Biron CA;O'Farrelly C;Ryan EJ; (2016) Immune Cell Profiling of IFN-λ Response Shows pDCs Express Highest Level of IFN-λR1 and Are Directly Responsive via the JAK-STAT Pathway.. Journal Of Interferon & Cytokine Research : The Official Journal Of The International Society For Interferon And Cytokine Research

Dunne MR;Ryan C;Nolan B;Tosetto M;Geraghty R;Winter DC;O'Connell PR;Hyland JM;Doherty GA;Sheahan K;Ryan EJ;Fletcher JM; (2016) Enrichment of Inflammatory IL-17 and TNF-α Secreting CD4(+) T Cells within Colorectal Tumors despite the Presence of Elevated CD39(+) T Regulatory Cells and Increased Expression of the Immune Checkpoint Molecule, PD-1.. Frontiers In Oncology

Lee CS;Murphy DJ;McMahon C;Nolan B;Cullen G;Mulcahy H;Sheahan K;Barnes E;Fennelly D;Ryan EJ;Doherty GA; (2015) Visceral Adiposity is a Risk Factor for Poor Prognosis in Colorectal Cancer Patients Receiving Adjuvant Chemotherapy.. Journal Of Gastrointestinal Cancer

Flood B;Oficjalska K;Laukens D;Fay J;O'Grady A;Caiazza F;Heetun Z;Mills KH;Sheahan K;Ryan EJ;Doherty GA;Kay E;Creagh EM; (2015) Altered expression of caspases-4 and -5 during inflammatory bowel disease and colorectal cancer: Diagnostic and therapeutic potential.. Clinical And Experimental Immunology

Gibson DJ;Elliott L;McDermott E;Tosetto M;Keegan D;Byrne K;Martin ST;Rispens T;Cullen G;Mulcahy HE;Cheifetz AS;Moss AC;Robson SC;Doherty GA;Ryan EJ; (2015) Heightened Expression of CD39 by Regulatory T Lymphocytes Is Associated with Therapeutic Remission in Inflammatory Bowel Disease.. Inflammatory bowel diseases

Caiazza F;Ryan EJ;Doherty G;Winter DC;Sheahan K; (2015) Estrogen receptors and their implications in colorectal carcinogenesis.. Frontiers In Oncology

Caiazza F;Elliott L;Fennelly D;Sheahan K;Doherty GA;Ryan EJ; (2015) Targeting EGFR in metastatic colorectal cancer beyond the limitations of KRAS status: alternative biomarkers and therapeutic strategies.. Biomarkers in medicine

Kelly A;Ryan EJ;O'Farrelly C; (2014) Reply to: "Dendritic cell subset composition in the human liver is more complex than it seems"..

Kelly, A.;Fahey, R.;Fletcher, J.M.;Keogh, C.;Carroll, A.G.;Siddachari, R.;Geoghegan, J.;Hegarty, J.E.;Ryan, E.J.;O'Farrelly, C.; (2014) CD141+ myeloid dendritic cells are enriched in healthy human liver. Journal Of Hepatology

Kelly A;Fahey R;Fletcher JM;Keogh C;Carroll AG;Siddachari R;Geoghegan J;Hegarty JE;Ryan EJ;O'Farrelly C; (2014) CD141⁺ myeloid dendritic cells are enriched in healthy human liver.. Journal Of Hepatology

O'Toole A;Michielsen AJ;Nolan B;Tosetto M;Sheahan K;Mulcahy HE;Winter DC;Hyland JM;O'Connell PR;Fennelly D;O'Donoghue D;O'Sullivan J;Doherty GA;Ryan EJ; (2014) Tumour microenvironment of both early- and late-stage colorectal cancer is equally immunosuppressive.. British Journal Of Cancer

Lee CS;Ryan EJ;Doherty GA; (2014) Gastro-intestinal toxicity of chemotherapeutics in colorectal cancer: the role of inflammation.. World Journal Of Gastroenterology

Gibson DJ;Ryan EJ;Doherty GA; (2013) Keeping the bowel regular: the emerging role of Treg as a therapeutic target in inflammatory bowel disease.. Inflammatory bowel diseases

Stevenson NJ;Bourke NM;Ryan EJ;Binder M;Fanning L;Johnston JA;Hegarty JE;Long A;O'Farrelly C; (2013) Hepatitis C virus targets the interferon-α JAK/STAT pathway by promoting proteasomal degradation in immune cells and hepatocytes.. Febs Letters

Michielsen AJ;O'Sullivan JN;Ryan EJ; (2012) Tumor conditioned media from colorectal cancer patients inhibits dendritic cell maturation.. Oncoimmunology

Michielsen AJ;Ryan EJ;O'Sullivan JN; (2012) Dendritic cell inhibition correlates with survival of colorectal cancer patients on bevacizumab treatment.. Oncoimmunology

Nanda KS;Brady JJ;Murray BF;Sullivan O;Fearon U;McKenna MJ;Hegarty JE;O'Farrelly C;Ryan EJ; (2012) Elevated circulating osteoprotegerin and reduced matrix-metalloprotease-9 in post-menopausal women with chronic Hepatitis C virus infection.. Cytokine

Michielsen AJ;Noonan S;Martin P;Tosetto M;Marry J;Biniecka M;Maguire AA;Hyland JM;Sheahan KD;O'Donoghue DP;Mulcahy HE;Fennelly D;Ryan EJ;O'Sullivan JN; (2012) Inhibition of dendritic cell maturation by the tumor microenvironment correlates with the survival of colorectal cancer patients following bevacizumab treatment.. Molecular cancer therapeutics

Sarwar S;Ryan EJ;Iqbal M;McCormick PA;O'Farrelly C;Hegarty J; (2012) Rapid, early and sustained virological responses in a cohort of Irish patients treated with pegylated interferon and ribavirin for chronic hepatitis C virus infection.. Irish journal of medical science

Michielsen AJ;Hogan AE;Marry J;Tosetto M;Cox F;Hyland JM;Sheahan KD;O'Donoghue DP;Mulcahy HE;Ryan EJ;O'Sullivan JN; (2011) Tumour tissue microenvironment can inhibit dendritic cell maturation in colorectal cancer.. Plos One

Ryan EJ;O'Farrelly C; (2011) The affect of chronic hepatitis C infection on dendritic cell function: a summary of the experimental evidence.. Journal Of Viral Hepatitis

Walsh CE;Ryan EJ;O'Farrelly C;Golden-Mason L;FitzGerald O;Veale DJ;Bresnihan B;Fearon U; (2011) Differential expression of NK receptors CD94 and NKG2A by T cells in rheumatoid arthritis patients in remission compared to active disease.. Plos One

Ryan EJ;Stevenson NJ;Hegarty JE;O'Farrelly C; (2011) Chronic hepatitis C infection blocks the ability of dendritic cells to secrete IFN-α and stimulate T-cell proliferation.. Journal Of Viral Hepatitis

Ryan EJ;Dring M;Ryan CM;McNulty C;Stevenson NJ;Lawless MW;Crowe J;Nolan N;Hegarty JE;O'Farrelly C; (2010) Variant in CD209 promoter is associated with severity of liver disease in chronic hepatitis C virus infection.. Human Immunology

Tajuddin T;Ryan EJ;Norris S;Hegarty JE;O'Farrelly C; (2010) Interferon-α suppressed granulocyte colony stimulating factor production is reversed by CL097, a TLR7/8 agonist.. Journal Of Gastroenterology And Hepatology

Michielsen, A.J.;O'Sullivan, J.N.;Ryan, E.J.; (2010) Recent advances in the development of novel therapeutics targeting dendritic cells. Recent Patents On Endocrine, Metabolic And Immune Drug Discovery

Nanda KS;Ryan EJ;Murray BF;Brady JJ;McKenna MJ;Nolan N;O'Farrelly C;Hegarty JE; (2009) Effect of chronic hepatitis C virus infection on bone disease in postmenopausal women.. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association

Stevenson NJ;Addley MR;Ryan EJ;Boyd CR;Carroll HP;Paunovic V;Bursill CA;Miller HC;Channon KM;McClurg AE;Armstrong MA;Coulter WA;Greaves DR;Johnston JA; (2009) CCL11 blocks IL-4 and GM-CSF signaling in hematopoietic cells and hinders dendritic cell differentiation via suppressor of cytokine signaling expression..

Ryan EJ;Magaletti D;Draves KE;Clark EA; (2009) Ligation of dendritic cell-associated lectin-1 induces partial maturation of human monocyte derived dendritic cells.. Human Immunology

McGrath E;Ryan EJ;Lynch L;Golden-Mason L;Mooney E;Eogan M;O'Herlihy C;O'Farrelly C; (2009) Changes in endometrial natural killer cell expression of CD94, CD158a and CD158b are associated with infertility.. American Journal Of Reproductive Immunology (New York, N.Y. : 1989)

Rowan, A.G.;Fletcher, J.M.;Ryan, E.J.;Moran, B.;Hegarty, J.E.;O'Farrelly, C.;Mills, K.H.G.; (2008) Hepatitis C virus-specific Th17 cells are suppressed by virus-induced TGF-β. Journal Of Immunology

Rowan AG;Fletcher JM;Ryan EJ;Moran B;Hegarty JE;O'Farrelly C;Mills KH; (2008) Hepatitis C virus-specific Th17 cells are suppressed by virus-induced TGF-beta.. Journal of immunology (Baltimore, Md. : 1950)

Golden-Mason L;Madrigal-Estebas L;McGrath E;Conroy MJ;Ryan EJ;Hegarty JE;O'Farrelly C;Doherty DG; (2008) Altered natural killer cell subset distributions in resolved and persistent hepatitis C virus infection following single source exposure.. Gut

Harenberg A;Guillaume F;Ryan EJ;Burdin N;Spada F; (2008) Gene profiling analysis of ALVAC infected human monocyte derived dendritic cells.. Vaccine

Zaman MB;Leonard MO;Ryan EJ;Nolan NP;Hoti E;Maguire D;Mulcahy H;Traynor O;Taylor CT;Hegarty JE;Geoghegan JG;O'Farrelly C; (2007) Lower expression of Nrf2 mRNA in older donor livers: a possible contributor to increased ischemia-reperfusion injury?. Transplantation

Ryan EJ;Harenberg A;Burdin N; (2007) The Canarypox-virus vaccine vector ALVAC triggers the release of IFN-gamma by Natural Killer (NK) cells enhancing Th1 polarization.. Vaccine

Bengtsson AK;Ryan EJ;Giordano D;Magaletti DM;Clark EA; (2004) 17beta-estradiol (E2) modulates cytokine and chemokine expression in human monocyte-derived dendritic cells.. Blood

Olson NE;Graves JD;Shu GL;Ryan EJ;Clark EA; (2003) Caspase activity is required for stimulated B lymphocytes to enter the cell cycle.. Journal of immunology (Baltimore, Md. : 1950)

Craxton A;Magaletti D;Ryan EJ;Clark EA; (2003) Macrophage- and dendritic cell--dependent regulation of human B-cell proliferation requires the TNF family ligand BAFF.. Blood

Olson, N.E.;Graves, J.D.;Shu, G.L.;Ryan, E.J.;Clark, E.A.; (2003) Caspase activity is required for stimulated B Lymphocytes to enter the cell cycle. Journal Of Immunology

Ryan, E.J.; (2003) Dendritic cell-associated lectin-1 (DCAL-1). Modern Aspects Of Immunobiology

Bengtsson, A.K.;Ryan, E.J.; (2002) Immune function of the decoy receptor osteoprotegerin. Critical Reviews In Immunology

Ryan EJ;Marshall AJ;Magaletti D;Floyd H;Draves KE;Olson NE;Clark EA; (2002) Dendritic cell-associated lectin-1: a novel dendritic cell-associated, C-type lectin-like molecule enhances T cell secretion of IL-4.. Journal of immunology (Baltimore, Md. : 1950)

Bengtsson AK;Ryan EJ; (2002) Immune function of the decoy receptor osteoprotegerin.. Critical Reviews In Immunology

Ryan, E.J.;Marshall, A.J.;Magaletti, D.;Floyd, H.;Draves, K.E.;Olson, N.E.;Clark, E.A.; (2002) Dendritic cell-associated lectin-1: A novel dendritic cell-associated, C-type lectin-like molecule enhances T cell secretion of IL-4. Journal Of Immunology

Ryan EJ;Daly LM;Mills KH; (2001) Immunomodulators and delivery systems for vaccination by mucosal routes..

Ryan EJ;Daly LM;Mills KH; (2001) Immunomodulators and delivery systems for vaccination by mucosal routes.. Trends In Biotechnology

Ryan EJ;Nilsson L;Kjellman N;Gothefors L;Mills KH; (2000) Booster immunization of children with an acellular pertussis vaccine enhances Th2 cytokine production and serum IgE responses against pertussis toxin but not against common allergens.. Clinical And Experimental Immunology

Ryan, E.J.;McNeela, E.;Pizza, M.;Rappuoli, R.;O'Neill, L.;Mills, K.H.G.; (2000) Modulation of innate and acquired immune responses by Escherichia coli heat-labile toxin: Distinct pro- and anti-inflammatory effects of the nontoxic AB complex and the enzyme activity. Journal Of Immunology

Ryan EJ;McNeela E;Pizza M;Rappuoli R;O'Neill L;Mills KH; (2000) Modulation of innate and acquired immune responses by Escherichia coli heat-labile toxin: distinct pro- and anti-inflammatory effects of the nontoxic AB complex and the enzyme activity.. Journal Of Immunology

McGuirk P;Johnson PA;Ryan EJ;Mills KH; (2000) Filamentous hemagglutinin and pertussis toxin from Bordetella pertussis modulate immune responses to unrelated antigens..

Ryan, E.J.;Mcneela, E.;Murphy, G.A.;Stewart, H.;O'Hagan, D.;Pizza, M.;Rappuoli, R.;Mills, K.H.G.; (1999) Mutants of Escherichia coli heat-labile toxin act as effective mucosal adjuvants for nasal delivery of an acellular pertussis vaccine: Differential effects of the nontoxic AB complex and enzyme activity on Th1 and Th2 cells. Infection And Immunity

Ryan EJ;McNeela E;Murphy GA;Stewart H;O'hagan D;Pizza M;Rappuoli R;Mills KH; (1999) Mutants of Escherichia coli heat-labile toxin act as effective mucosal adjuvants for nasal delivery of an acellular pertussis vaccine: differential effects of the nontoxic AB complex and enzyme activity on Th1 and Th2 cells.. Infection And Immunity

Mills, K.H.;Brady, M.;Ryan, E.;Mahon, B.P.; (1998) A respiratory challenge model for infection with Bordetella pertussis: application in the assessment of pertussis vaccine potency and in defining the mechanism of protective immunity.. Developments In Biological Standardization

Mills, K.H.G.;Ryan, M.;Ryan, E.;Mahon, B.P.; (1998) A murine model in which protection correlates with pertussis vaccine efficacy in children reveals complementary roles for humoral and cell- mediated immunity in protection against Bordetella pertussis. Infection And Immunity

Mills KH;Brady M;Ryan E;Mahon BP; (1998) A respiratory challenge model for infection with Bordetella pertussis: application in the assessment of pertussis vaccine potency and in defining the mechanism of protective immunity.. Developments In Biological Standardization

Ryan M;Murphy G;Ryan E;Nilsson L;Shackley F;Gothefors L;Oymar K;Miller E;Storsaeter J;Mills KH; (1998) Distinct T-cell subtypes induced with whole cell and acellular pertussis vaccines in children.. Journal Of Immunology

Mills KH;Ryan M;Ryan E;Mahon BP; (1998) A murine model in which protection correlates with pertussis vaccine efficacy in children reveals complementary roles for humoral and cell-mediated immunity in protection against Bordetella pertussis.. Infection And Immunity