Dr. Audrey Tierney
Biography
Audrey obtained a BSc (Hons) in Human Nutrition and Dietetics in 2003 from Trinity College Dublin (TCD) and Dublin Institute of Technology and a PhD in Nutrition in 2008 (TCD) where she was the lead dietitian on an EU (FP6) funded dietary intervention trial (LIPGENE Workpackage 1.2) investigating the effects of dietary fat on insulin resistance in Metabolic Syndrome. After a post-doctoral position at University College Dublin in the Nutrigenomic Research group, looking at the impact of genetic predisposition and response to dietary changes, she moved to Australia where she resided for 10 years, working in both the clinical (Alfred Health) and academic fields (La Trobe University). Audrey joined the School of Allied Health in July 2017 and is Senior Lecturer and Course Director for the Msc in Human Nutrition and Dietetics.Research Interests
Audrey is a well-established active researcher in the area of clinical nutrition and dietetics with her research recognised both nationally and internationally.Audrey's doctoral and post-doctoral studies were based on EU funded (Euro12.5m) international clinical trials in the prevention and management of Metabolic Syndrome and Type 2 Diabetes (T2DM) from the basic science to the molecular level. Building on this research, which focussed primarily on the effect of dietary fat, specifically monounsaturated fat, Audrey joined the Mediterranean Diet Research Group at La Trobe University in 2013 where a whole of diet approach based on the traditional Cretan Mediterranean Diet and its effects on metabolic health has primarily been the topic of her research and grant applications.Current Active Research Projects in the Mediterranean Diet Area for which Audrey is a principle or co/associate investigator include:- MEDINA MEDIterranean diet in Non Alcoholic fatty liver disease (RCT).- AUSMED The AUStralian MEDiterranean Diet Heart Trial (RCT)- MediBrain Dietary Intervention to enhance cognitive performance in T2DM.- Polyphenol Study The effect of olive oil on markers of cardiovascular disease risk.Audrey's clinical expertise is in the areas of respiratory and intensive care medicine. She has been awarded grants in these areas with a focus on translational research to influence practice change. During Audrey's time as a Clinical Specialist at Alfred Health with joint appointments at Monash University and La Trobe University, Melbourne, she led the research portfolio and managed dietary intervention trials and observational studies in Haematology, Obstetrics, Hepatology, Respiratory and ICU.Current Research Projects in the Clinical Nutrition and Dietetics Area for which Audrey is principle investigator and/or coinvestigator include:- Effects of gene potentiators on nutritional status and body composition in Cystic Fibrosis.- Segmental Intestinal Permeability in the critically ill mechanically ventilated adult patient versus healthy controls.- Energy requirements of critically ill obese patients: does goal directed nutrition using indirect calorimetry improve energy delivery?
Professional Activities
Association
- Dietitians Registration Board, CORU Regulating Health and Social Care Professionals
- Professional Body, Irish Nutrition and Dietetic Institute
- Professional Body, Dietitians Association of Australia
- Allied Health Member, European Cystic Fibrosis Society
- Member, Nutrition Society
- Member, European Society of Parenteral and Enteral Nutrition
- Member, Australasian Society of Parenteral and Enteral Nutrition
Peer Reviewed Journals
The effect of high-polyphenol extra virgin olive oil on cardiovascular risk factors: a systematic review and meta-analysis
Elena S George, Skye Marshall, Hannah L Mayr, Gina L Trakman, Oana A Tatucu-Babet, Annie-Claude M Lassemillante, Andrea Bramley, Anjana J Reddy, Adrienne Forsyth, Audrey C Tierney, Colleen J Thomas, Catherine Itsiopoulos & Wolfgang Marx (2018) The effect of high-polyphenol extra virgin olive oil on cardiovascular risk factors: a systematic review and meta-analysis. Critical Reviews In Food Science And Nutrition
Non Alcoholic Fatty Liver Disease Patients Attending Two Metropolitan Hospitals in Melbourne, Australia; High Risk Status and Low Prevalence
Elena S George, Stuart K Roberts, Amanda J Nicoll, Anjana Reddy, Tonya Paris, Catherine Itsiopoulos, Audrey C Tierney (2018) Non Alcoholic Fatty Liver Disease Patients Attending Two Metropolitan Hospitals in Melbourne, Australia; High Risk Status and Low Prevalence. Internal Medicine Journal
The AUStralian MEDiterranean diet heart trial (AUSMED heart trial): A randomized clinical trial in secondary prevention of coronary heart disease in a multi-ethnic Australian population: Study protocol
Catherine Itsiopoulos, Teagan Kucianski, Hannah L. Mayr, William J. van Gaal, Miguel Angel Martinez-Gonzalez, Hassan Vally, Michael Kingsley, Antigone Kouris-Blazos PhD, Jessica Radcliffe, Leonie Segal, Laima Brazionis1,, Agus Salim, Audrey C. Tierney, Kerin O'Dea, Andrew Wilson, Colleen J. Thomas (2018) The AUStralian MEDiterranean diet heart trial (AUSMED heart trial): A randomized clinical trial in secondary prevention of coronary heart disease in a multi-ethnic Australian population: Study protocol. American Heart Journal :4-11
Targeted Full Energy and Protein Delivery in Critically Ill Patients: A Pilot Randomised Contol Trial (FEED Trial)
Fetterplace K, Deane A, Tierney A, Beach L, Knight L, Presnell J, Rechnitzer T, Forsyth A, Gill B, Mourtzakis M, MacIsaac C (2018) Targeted Full Energy and Protein Delivery in Critically Ill Patients: A Pilot Randomised Contol Trial (FEED Trial) . JPEN. Journal of parenteral and enteral nutrition
Association of energy and protein delivery on skeletal muscle mass changes in critically ill adults: a systematic review
Lambell K, King S, Forsyth A, Tierney AC (2018) Association of energy and protein delivery on skeletal muscle mass changes in critically ill adults: a systematic review. JPEN. Journal of parenteral and enteral nutrition :1-11
The Effect of Resveratrol Supplementation on Cognitive Performance and Mood in Adults: A Systematic Literature Review and Meta-Analysis of Randomised Controlled Trials
Marx W, Kelly J, Marshall S, Cutajar J, Annois B, Pipingas A, Tierney A, Itsiopoulos C (2018) The Effect of Resveratrol Supplementation on Cognitive Performance and Mood in Adults: A Systematic Literature Review and Meta-Analysis of Randomised Controlled Trials. Nutrition Reviews
Practical Dietary Recommendations for the Prevention and Management of Nonalcoholic Fatty Liver Disease in Adults.
Elena S George, Adrienne Forsyth, Catherine Itsiopoulos, Amanda J Nicoll, Marno Ryan, Siddharth Sood, Stuart K Roberts, Audrey C Tierney (2018) Practical Dietary Recommendations for the Prevention and Management of Nonalcoholic Fatty Liver Disease in Adults.. Advances In Nutrition And Cancer :30-40
Randomization to 6-month Mediterranean diet compared with a low-fat diet leads to improvement in Dietary Inflammatory Index scores in patients with coronary heart disease: the AUSMED Heart Trial
Hannah L Mayr, Colleen J Thomas, Audrey C Tierney, Teagan Kucianski, Elena S George, Miguel Ruiz-Canela, James R. Hebert, Nitin Shivappa, Catherine Itsiopoulos (2018) Randomization to 6-month Mediterranean diet compared with a low-fat diet leads to improvement in Dietary Inflammatory Index scores in patients with coronary heart disease: the AUSMED Heart Trial. Nutrition Research :94-107
A Mediterranean Diet Model in Australia: Strategies for Translating the Traditional Mediterranean Diet into a Multicultural Setting
George ES, Kucianski T, Mayr HL, Moschonis G, Tierney AC, Itsiopoulos C (2018) A Mediterranean Diet Model in Australia: Strategies for Translating the Traditional Mediterranean Diet into a Multicultural Setting. Nutrients :E465-
Improvement in dietary inflammatory index score after 6-month dietary intervention is associated with reduction in interleukin-6 in patients with coronary heart disease: The AUSMED heart trial
Hannah L Mayr, Catherine Itsiopoulos, Audrey C Tierney, Miguel Ruiz-Canela, James R.Hebert, Nitin Shivappa, Colleen J Thomas (2018) Improvement in dietary inflammatory index score after 6-month dietary intervention is associated with reduction in interleukin-6 in patients with coronary heart disease: The AUSMED heart trial. Nutrition Research :108-121
APOE genotype influences insulin resistance, apolipoprotein CII and CIII according to plasma fatty acid profile in the Metabolic Syndrome.
Fallaize R, Carvalho-Wells AL, Tierney AC, Marin C, Kieć-Wilk B, Dembińska-Kieć A, Drevon CA, DeFoort C, Lopez-Miranda J, Risérus U, Saris WH, Blaak EE, Roche HM, Lovegrove JA (2017) APOE genotype influences insulin resistance, apolipoprotein CII and CIII according to plasma fatty acid profile in the Metabolic Syndrome.. Scientific Reports :6274-
The effects of diet and lifestyle interventions on insulin resistance in patients with non-alcoholic fatty liver disease: a systematic review
Paris T, George ES, Roberts SK, Tierney AC (2017) The effects of diet and lifestyle interventions on insulin resistance in patients with non-alcoholic fatty liver disease: a systematic review. European Journal Of Gastroenterology & Hepatology :867-878
Improvement in exercise duration, lung function and well-being in G551D-cystic Fibrosis patients: a double-blind, placebo-controlled, randomised, cross-over study with ivacaftor treatment.
Dominic T Keating, Deirdre Edgeworth, Matthew Ellis, Brenda Button, Elyssa Williams, Denise Clark, Audrey Tierney, Stephane Heritier, Anastase Kotsimbos, John Wilson (2017) Improvement in exercise duration, lung function and well-being in G551D-cystic Fibrosis patients: a double-blind, placebo-controlled, randomised, cross-over study with ivacaftor treatment.. Clinical Science :2037-2045
Mediterranean-type diets and inflammatory markers in patients with coronary heart disease: a systematic review and meta-analysis
Hannah L Mayr, Audrey C Tierney, Colleen J Thomas, Miguel Ruiz-Canela, Jessica Radcliffe, Catherine Itsiopoulos (2017) Mediterranean-type diets and inflammatory markers in patients with coronary heart disease: a systematic review and meta-analysis. Nutrition Research
A behavioural nutrition intervention for obese pregnant women: Effects on diet quality, weight gain and the incidence of gestational diabetes
Opie RS, Neff M, Tierney AC (2016) A behavioural nutrition intervention for obese pregnant women: Effects on diet quality, weight gain and the incidence of gestational diabetes. Australian & New Zealand Journal Of Obstetrics & Gynaecology :364-373
Impact of a lifestyle modification program on the metabolic syndrome and associated risk factors in long-term survivors of stem cell transplantation.
Viner Smith E, Tierney AC, Klarica D, Walker P, Avery S. (2016) Impact of a lifestyle modification program on the metabolic syndrome and associated risk factors in long-term survivors of stem cell transplantation.. Bone Marrow Transplantation :722-724
A randomised controlled trial of a Mediterranean Dietary Intervention for Adults with Non Alcoholic Fatty Liver Disease (MEDINA): study protocol
Papamiltiadous, Elena S.; Roberts, Stuart K.; Nicoll, Amanda J.; Tierney AC. (2016) A randomised controlled trial of a Mediterranean Dietary Intervention for Adults with Non Alcoholic Fatty Liver Disease (MEDINA): study protocol. Bmc Gastroenterology
Effect of probiotics on respiratory, gastrointestinal and nutritional outcomes in patients with cystic fibrosis: A systematic review
Anderson JL, Miles C, Tierney AC (2016) Effect of probiotics on respiratory, gastrointestinal and nutritional outcomes in patients with cystic fibrosis: A systematic review. Journal Of Cystic Fibrosis :186-197
The Prevalence of Underprescription or Overprescription of Energy Needs in Critically Ill Mechanically Ventilated Adults as Determined by Indirect Calorimetry: A Systematic Literature Review
Tatucu-Babet OA, Ridley EJ, Tierney AC (2015) The Prevalence of Underprescription or Overprescription of Energy Needs in Critically Ill Mechanically Ventilated Adults as Determined by Indirect Calorimetry: A Systematic Literature Review . JPEN. Journal of parenteral and enteral nutrition :212-215
Insulin resistance determines a differential response to changes in dietary fat modification on metabolic syndrome risk factors: the LIPGENE study
Yubero-Serrano EM, Delgado-Lista J, Tierney AC2, Perez-Martinez P, Garcia-Rios A, Alcala-Diaz JF, Castaño JP, Tinahones FJ, Drevon CA, Defoort C, Blaak EE, Dembinska-Kieć A, Risérus U, Lovegrove JA, Perez-Jimenez F, Roche HM, Lopez-Miranda J. (2015) Insulin resistance determines a differential response to changes in dietary fat modification on metabolic syndrome risk factors: the LIPGENE study . American Journal Of Clinical Nutrition :1509-1517
Monounsaturated fatty acid enriched high fat-diets impede adipose NLRP3 inflammasome mediated IL-1β secretion and insulin resistance despite obesity
Finucane OM, Lyons CL, Murphy AM, Reynolds CM, Klinger R, Healy NP, Cooke A, Coll R, McAllan L, Nilaweera K, O'Reilly M, Tierney AC, Morine MJ, Alcala-Diaz JF, Lopez-Miranda J, O'Connor DP, Neill LO, McGillicuddy FC, Roche HM (2015) Monounsaturated fatty acid enriched high fat-diets impede adipose NLRP3 inflammasome mediated IL-1β secretion and insulin resistance despite obesity. Diabetes :2116-2128
Obesity and body fat classification in the metabolic syndrome: Impact on cardiometabolic risk metabotype
Phillips CM, Tierney AC, Perez-Martinez P, Defoort C, Blaak EE, Gjelstad IM, Lopez-Miranda J, Kiec-Klimczak M, Malczewska-Malec M, Drevon CA, Hall W, Lovegrove JA, Karlstrom B, Risérus U, Roche HM (2013) Obesity and body fat classification in the metabolic syndrome: Impact on cardiometabolic risk metabotype. Obesity :154-161
Insulin receptor substrate-2 gene variants in subjects with metabolic syndrome: Association with plasma monounsaturated and n-3 polyunsaturated fatty acid levels and insulin resistance
Perez-Martinez P, Delgado-Lista J, Garcia-Rios A, Tierney AC, Gulseth HL, Williams CM, Karlström B, Kieć-Wilk B, Blaak EE, Helal O, Saris WH, Defoort C, Drevon CA, Lovegrove JA, Dembinska-Kieć A, Riserus U, Roche HM, Lopez-Miranda J (2012) Insulin receptor substrate-2 gene variants in subjects with metabolic syndrome: Association with plasma monounsaturated and n-3 polyunsaturated fatty acid levels and insulin resistance. Molecular Nutrition & Food Research :309-315
Impact of dietary fat quantity and quality on skeletal muscle fatty acid metabolism in subjects with the metabolic syndrome
Jans A, van Hees AM, Gjelstad IM, Sparks LM, Tierney AC, Risérus U, Drevon CA, Schrauwen P, Roche HM, Blaak EE (2012) Impact of dietary fat quantity and quality on skeletal muscle fatty acid metabolism in subjects with the metabolic syndrome. Metabolism-Clinical And Experimental :1554-1565
A low-fat high-carbohydrate diet supplemented with long-chain n-3 PUFA reduces the risk of the metabolic syndrome
Paniagua JA, Pérez-Martinez P, Gjelstad IM, Tierney AC, Delgado-Lista J, Defoort C, Blaak EE, Risérus U, Drevon CA, Kiec-Wilk B, Lovegrove JA, Roche HM, López-Miranda J (2011) A low-fat high-carbohydrate diet supplemented with long-chain n-3 PUFA reduces the risk of the metabolic syndrome. Atherosclerosis :443-450
Transcriptional metabolic inflexibility in skeletal muscle among individuals with increasing insulin resistance
Jans A, Sparks LM, van Hees AM, Gjelstad IM, Tierney AC, Risérus U, Drevon CA, Roche HM, Schrauwen P, Blaak EE (2011) Transcriptional metabolic inflexibility in skeletal muscle among individuals with increasing insulin resistance. Obesity
Transcriptomic coordination in the human metabolic network reveals links between n-3 fat intake, adipose tissue gene expression and metabolic health
Morine MJ, Tierney AC, van Ommen B, Daniel H, Toomey S, Gjelstad IM, Gormley IC, Pérez-Martinez P, Drevon CA, López-Miranda J, Roche HM (2011) Transcriptomic coordination in the human metabolic network reveals links between n-3 fat intake, adipose tissue gene expression and metabolic health. Plos Computational Biology
Gene-nutrient interactions in the metabolic syndrome: single nucleotide polymorphisms in ADIPOQ and ADIPOR1 interact with plasma saturated fatty acids to modulate insulin resistance.
Ferguson JF, Phillips CM, Tierney AC, Pérez-Martínez P, Defoort C, Helal O, Lairon D, Planells R, Shaw DI, Lovegrove JA, Gjelstad IM, Drevon CA, Blaak EE, Saris WH, Leszczynska-Golabek I, Kiec-Wilk B, Risérus U, Karlström B, Miranda JL, Roche HM (2010) Gene-nutrient interactions in the metabolic syndrome: single nucleotide polymorphisms in ADIPOQ and ADIPOR1 interact with plasma saturated fatty acids to modulate insulin resistance.. American Journal Of Clinical Nutrition :794-801
Dietary fat modifications and blood pressure in subjects with the metabolic syndrome in the LIPGENE dietary intervention study
Gulseth HL, Gjelstad IM, Tierney AC, Shaw DI, Helal O, Hees AM, Delgado-Lista J, Leszczynska-Golabek I, Karlström B, Lovegrove J, Defoort C, Blaak EE, Lopez-Miranda J, Dembinska-Kiec A, Risérus U, Roche HM, Birkeland KI, Drevon CA (2010) Dietary fat modifications and blood pressure in subjects with the metabolic syndrome in the LIPGENE dietary intervention study. The British journal of nutrition :160-163
Effects of dietary fat modification on oxidative stress and inflammatory markers in the LIPGENE study
Petersson H, Risérus U, McMonagle J, Gulseth HL, Tierney AC, Morange S, Helal O, Shaw DI, Ruano JA, López-Miranda J, Kieć-Wilk B, Gołąbek I, Blaak EE, Saris WH, Drevon CA, Lovegrove JA, Roche HM, Basu S (2010) Effects of dietary fat modification on oxidative stress and inflammatory markers in the LIPGENE study. The British journal of nutrition :1357-1362
Serum vitamin D concentration does not predict insulin action or secretion in European subjects with the metabolic syndrome
Gulseth HL, Gjelstad IM, Tierney AC, Lovegrove JA, Defoort C, Blaak EE, Lopez-Miranda J, Kiec-Wilk B, Risérus U, Roche HM, Drevon CA, Birkeland KI (2010) Serum vitamin D concentration does not predict insulin action or secretion in European subjects with the metabolic syndrome. Diabetes Care :923-925
Effects of dietary fat modification on insulin sensitivity and on other risk factors of the metabolic syndrome-LIPGENE: a European randomized dietary intervention study
Tierney AC, McMonagle J, Shaw DI, Gulseth HL, Helal O, Saris WH, Paniagua JA, Gołąbek-Leszczyñska I, Defoort C, Williams CM, Karsltröm B, Vessby B, Dembinska-Kiec A, López-Miranda J, Blaak EE, Drevon CA, Gibney MJ, Lovegrove JA, Roche HM (2010) Effects of dietary fat modification on insulin sensitivity and on other risk factors of the metabolic syndrome-LIPGENE: a European randomized dietary intervention study. International journal of obesity (2005) :800-809
Lipoprotein profile, plasma ischemia modified albumin and LDL density change in the course of postprandial lipemia. Insights from the LIPGENE study
Hartwich J, Leszczynska-Golabek I, Kiec-Wilk B, Siedlecka D, Perez-Martinez P, Lopez-Miranda J, Tierney A, Monagle JM, Roche HM, Defoort C, Wolkow P, Dembinska-Kiec A (2010) Lipoprotein profile, plasma ischemia modified albumin and LDL density change in the course of postprandial lipemia. Insights from the LIPGENE study. Scandinavian Journal Of Clinical & Laboratory Investigation :201-208
The effect of the plasma n-3/n-6 polyunsaturated fatty acid ratio on the dietary LDL phenotype transformation - insights from the LIPGENE study
Hartwich J, Malec MM, Partyka L, Pérez-Martinez P, Marin C, López-Miranda J, Tierney AC, Mc Monagle J, Roche HM, Defoort C, Wolkow P, Dembinska-Kieć A (2009) The effect of the plasma n-3/n-6 polyunsaturated fatty acid ratio on the dietary LDL phenotype transformation - insights from the LIPGENE study. Clinical Nutrition :510-515
LIPGENE food exchange model for alteration of dietary fat quantity and quality, in free-living participants with the Metabolic Syndrome from eight European countries
Tierney AC*, Shaw DI*, McCarthy S, Upritchard J, Vermunt S, Lovedal-Gulseth H, Drevon CA, Blaak E, Saris WHM, Karlstrom B, Helal O, Defoort C, Gallego R, Siedlecka D, Malczewska-Malec M, Lopez-Miranda J, Roche HM, Lovegrove JA (2009) LIPGENE food exchange model for alteration of dietary fat quantity and quality, in free-living participants with the Metabolic Syndrome from eight European countries. The British journal of nutrition :750-759
Gene-Nutrient Interactions in the Metabolic Syndrome
Phillips C, Tierney AC and Roche HM (2008) Gene-Nutrient Interactions in the Metabolic Syndrome. Journal Of Nutrigenetics And Nutrigenomics :136-151
The potential role of olive oil-derived MUFA in insulin sensitivity.
Tierney AC and Roche HM (2007) The potential role of olive oil-derived MUFA in insulin sensitivity.. Molecular nutrition & food research :1235-1248
Books
Food and Nutrition Throughout Life A comprehensive overview of food and nutrition in all stages of life.
Sharon Croxford, Catherine Itsiopoulos, Adrienne Forsyth, Regina Belski, Antonia Thodis, Sue Shepherd and Audrey Tierney (2015) Food and Nutrition Throughout Life A comprehensive overview of food and nutrition in all stages of life. . Australia : Allen and Unwin
Book Chapters
Early and middle adult (26-60 years)' in A comprehensive overview of food and nutrition in all stages of life
Audrey Tierney and Catherine Itsiopoulos (2015) Early and middle adult (26-60 years)' in A comprehensive overview of food and nutrition in all stages of life. Australia : Allen and Unwin Food and Nutrition Throughout Life: A comprehensive overview of food and nutrition in all stages of life
Edited Books
Other Journals
What is the Optimal Dietary Composition for NAFLD
George ES, Tierney AC, Campbell KL, Macdonald GA, Hickman IJ (2017) What is the Optimal Dietary Composition for NAFLD. Current Hepatology Reports :346-355
Quinoa seed lowers serum triglycerides in overweight and obese subjects - a dose-response randomized controlled clinical trial
Navarro-Perez, D; Radcliffe J; Tierney AC and Jois M. 2017 (2017) Quinoa seed lowers serum triglycerides in overweight and obese subjects - a dose-response randomized controlled clinical trial. Current Developments in Nutrition :e001321-
The Influence of the Australian Dietary Guidelines on Culinary Textbooks Used in Education over the last 30 years
Sharon Croxford, Jodie McGough, Audrey Tierney & Catherine Itsiopoulos (2017) The Influence of the Australian Dietary Guidelines on Culinary Textbooks Used in Education over the last 30 years. Journal of Culinary Science and Technology :1-15
Factors that influence dietary intake in adults with stable chronic obstructive pulmonary disease
Shalit N, Tierney A, Holland A, Miller B, Norris N and King S (2016) Factors that influence dietary intake in adults with stable chronic obstructive pulmonary disease. Nutrition and Dietetics :455-462
The Lipgene Food-Exchange Model: a tool to enable investigation of four diets distinct in fatty acid composition
Shaw DI, Tierney AC, McCarthy S, Uprichard J, Vermunt S, Roche HM, Lovegrove JA (2008) The Lipgene Food-Exchange Model: a tool to enable investigation of four diets distinct in fatty acid composition. The Proceedings of the Nutrition Society :E86-