Amira Mahdi is an Assistant Professor in Biomedical Sciences at the School of Medicine. Amira received a BSc. (Hons) in Biomedical Science from the University of Galway in 2016. Following this she was awarded an Irish Research Council Post-graduate Scholarship to undertake her PhD studies at the University of Limerick. Amira's PhD examined the role of newly synthesised proteins in the progression of breast cancer. Following this, Amira took up a post-doctoral researcher role as part of a Science Foundation Ireland Strategic Partnerships Award, in collaboration with Puma Biotechnology at the National Institute for Cellular Biotechnology (NICB) at Dublin City University (DCU).During her time at DCU, Amira worked on devising novel combination treatment strategies for HER2+ breast cancer. Amira joined the School of Medicine in September 2023. Her current research interests include the microenvironmental regulation of therapeutic resistance in breast cancer and investigating the interactions between cancer treatment and the blood brain barrier for the treatment of brain metastasis.
Research Interests
The microenvironmental regulation of therapeutic resistance in breast cancer
The interactions between cancer treatment and the blood brain barrier for the treatment of brain metastasis.
Professional Activities
Employment
2020 Dublin City University - Post-doctoral Researcher
Education
2016 National University of Ireland - Galway - BSc (Hons)
Mahdi A.F.;Nolan J.;O’Connor R.;Lowery A.J.;Allardyce J.M.;Kiely P.A.;McGourty K. (2023) Collagen-I influences the post-translational regulation, binding partners and role of Annexin A2 in breast cancer progression.
Frontiers In Oncology
Ashfield, Niall;Mahdi, Amira F.;Conlon, Neil T.;Crown, John;Collins, Denis M.; (2023) Reversible versus irreversible tyrosine kinase inhibitors (TKIs) combined with antibody-drug conjugates (ADCs) in HER2-positive (HER2+) breast cancer (BC) cell lines.
Cancer Research
Mahdi, Amira F.;Ashfield, Niall;Conlon, Neil T.;Crown, John;Collins, Denis M.; (2023) Pre-clinical study of amcenestrant and HER2-targeted therapies in HER2+/ER+ breast cancer cell line models.
Cancer Research
Mahdi, Amira F.;Conlon, Neil T.;Eli, Lisa D.;Diala, Irmina;Crown, John;Collins, Denis; (2022) Investigation of neratinib and endocrine therapy combinations in HER2 positive breast cancer models.
Cancer Research
O'Connor, Ruth I.;Mahdi, Amira F.;Nolan, Joanne;Dowling, Catriona M.;Dunne, Colum P.;Kiely, Patrick A.; (2022) How surgical site infection influences breast cancer cell recurrence and cancer cell reprogramming.
Cancer Research
O'Connor, Ruth I.;Mahdi, Amira F.;Nolan, Joanne;Dowling, Catriona M.;Dunne, Colum P.;Kiely, Patrick A.; (2022) How surgical site infection influences breast cancer cell recurrence and cancer cell reprogramming.
Cancer Research
Amira F. Mahdi, Beatrice Malacrida, Kieran McGourty, Aoife J. Lowery and Patrick A. Kiely (2018) Using in vitro models to identify newly synthesised proteins involved in the progression of breast cancer.
Cancer Research
Books
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Book Chapters
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Edited Books
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Other Journals
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Conference Publications
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(2019) Abstract 2027: Understanding the role and regulation of newly synthesized Annexin A2 in the progression of breast cancer.
American Association for Cancer Research
(2019) Abstract 1908: Using hierarchical clustering of differential gene expression patterns to study the contribution of the extracellular matrix in breast cancer.
Tumor Biology
