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Prof Philip Jakeman

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Professor and lead PI to the Human Science Research within the PESS Department and Centre for Interventions in Infection, Inflammation and Immunity. Research interests focus on regulatory and adaptive processes induced by nutrient intervention and physical activity. >€5m programme and project grant funding (EI/DAFM/FIRM/SFI) supports PDR/RA/PhD research investigating;

  • -bioactivity proteins and their derivatives in the regulation of muscle cell growth of murine cell lines in vitro and by stable isotope techniques in humans in vivo (www.FHI.ie;EI/DAFM/FIRM)
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  • -human body composition/anthropometric phenotype of healthy adults and disease states by dual energy x-ray absorptiometry (DXA) and bioelectric impedance analysis (BIA) www.ul.ie/bodycompositionstudy
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  • -clinical trials (RCTs) of the timing and composition of nutrient intake in the regulation of skeletal and skeletal muscle health (clintrials.gov CRT ID_NCT02529124, NTC03337971 and NCT03701113)
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  • -stable isotope studies of energy expenditure and dietary intake in the regulation of bone turnover in female distance runners (FDRs) at risk of osteopenia

Publications

Hettiarachchi, M.; Cooke, R.; Norton, C.; Jakeman, P. Temporal Change in Biomarkers of Bone Turnover Following Late Evening Ingestion of a Calcium-Fortified, Milk-Based Protein Matrix in Postmenopausal Women with Osteopenia. Nutrients 2019, 11, 1413. doi: 10.3390/nu1106141. https://www.mdpi.com/2072-6643/11/6/1413

 

Francis, P., Lyons, M., Piasecki, M., Mc Phee, J., Hind, K. & Jakeman, P. (2017) Measurement of Muscle Health in Aging. Biogerontology 2017 Dec; 18(6):901-911. doi: 10.1007/s10522-017-9697-5. https://www.ncbi.nlm.nih.gov/pubmed/28378095  

 

Norton C, Toomey CM, McCormack W, Francis P, Kerin E, Saunders J and Jakeman P. Protein supplementation at breakfast and lunch for 24 weeks beyond habitual intakes increases whole body lean tissue mass in healthy older adults. J Nutr. 2016, 146(1):65-69. doi: 10.3945/jn.115.219022. https://www.ncbi.nlm.nih.gov/pubmed/26581685  

 

Power O, Nongonierma AB, Jakeman P, FitzGerald RJ. Milk protein hydrolysates as a source of dipeptidyl peptidase IV inhibitory peptides for the management of type 2 diabetes. Proc Nutr Soc. 2014 Feb; 73(1):34-46. doi: 10.1017/S0029665113003601. https://www.ncbi.nlm.nih.gov/pubmed/24131508   

 

Leahy S, O’Neill C, Sohun R, Toomey C, Jakeman P. Generalised equations for the prediction of percentage body fat by anthropometry in adult men and women aged 18–81 years. Br J Nutr. 2013; 109(4):678-85. doi: 10.1017/S0007114512001870 http://www.ncbi.nlm.nih.gov/pubmed/22640975