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Prof Philip Jakeman

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Professor and lead PI to the Human Science Research with the PESS Department and Centre for Interventions in Infection, Inflammation and Immunity. Research interest focuses on the discovery of regulatory and adaptive processes induced by nutrient intervention and physical activity. Approx. €5m programme and project grant funding (EI/DAFM/FIRM/SFI) support PDR/RA/PhD research listed below;

  1. Human body composition/anthropometric phenotype in healthy adults and disease states by dual energy x-ray absorptiometry (DXA) and bioelectric impedance analysis (BIA) www.ul.ie/bodycompositionstudy
  2. Investigation of the bioactivity of milk proteins and their derivatives in the regulation of the entero-insular and entero-osseus axis in young and older adults (www.FHI.ie)
  3. Investigation of the bioactivity of milk proteins and their derivatives in the regulation of muscle cell growth of murine cell lines in vitro and by stable isotope techniques in humans in vivo (www.FHI.ie; DAFM/FIRM)
  4. Clinical trials (RCTs) to study the timing and composition of nutrient intake in the regulation of skeletal and skeletal muscle health healthy adults and post-menopausal women (clintrials.gov CRT ID_NCT0252914, NTC03337971 and NCT03701113)
  5. Stable isotope studies of energy expenditure and dietary intake in the regulation of bone turnover in female distance runners (FDRs) at risk of osteopenia.

Publications

Francis, P., Lyons, M., Piasecki, M., Mc Phee, J., Hind, K. & Jakeman, P. (2017) Measurement of Muscle Health in Aging. Biogerontology 2017 Dec; 18(6):901-911. doi: 10.1007/s10522-017-9697-5. https://www.ncbi.nlm.nih.gov/pubmed/28378095 PMID: 28378095

Norton C, Toomey CM, McCormack W, Francis P, Kerin E, Saunders J and Jakeman P. Protein supplementation at breakfast and lunch for 24 weeks beyond habitual intakes increases whole body lean tissue mass in healthy older adults. J Nutr. 2016, 146(1):65-69. doi: 10.3945/jn.115.219022. https://www.ncbi.nlm.nih.gov/pubmed/26581685 PMID: 26581685

Leahy S, O’Neill C, Sohun R, Toomey C, Jakeman P. Generalised equations for the prediction of percentage body fat by anthropometry in adult men and women aged 18–81 years. Br J Nutr. 2013; 109(4):678-85. doi: 10.1017/S0007114512001870 http://www.ncbi.nlm.nih.gov/pubmed/22640975 PMID: 22640975

Power O, Nongonierma AB, Jakeman P, FitzGerald RJ. Milk protein hydrolysates as a source of dipeptidyl peptidase IV inhibitory peptides for the management of type 2 diabetes. Proc Nutr Soc. 2014 Feb; 73(1):34-46. doi: 10.1017/S0029665113003601. https://www.ncbi.nlm.nih.gov/pubmed/24131508  PMID: 24131508

Leahy S, O'Neill C, Sohun R, Jakeman P. A comparison of dual energy X-ray absorptiometry and bioelectrical impedance analysis to measure total and segmental body composition in healthy young adults. Eur J Appl Physiol. 2012 Feb; 112(2):589-95. https://www.ncbi.nlm.nih.gov/pubmed/21614505 PMID: 21614505