Austin Stack is Professor and Foundation Chair of Medicine at the School of Medicine, University of Limerick and Consultant Nephrologist at University Hospital Limerick in Ireland. He received his medical degree from University College Dublin and completed his medical residency at the Mater University Hospital, followed by a combined clinical and research fellowship programme at the University of Michigan, USA. He trained in epidemiology and health outcomes research at the Kidney Epidemiology and Cost Centre (KECC), University of Michigan, and the United States Renal Data System (USRDS) Coordinating Centre and was Assistant Professor at the University of Texas Medical School in Houston, Texas, USA. He is a fellow of the American Society of Nephrology and Royal College of Physicians of Ireland.

Professor Stack’s research has addressed the epidemiology of chronic kidney disease (CKD) and acute kidney injury (AKI) in health systems, and their impact on clinical outcomes. He has a particular interest in modifiable risk factors for CKD including anaemia, iron deficiency, hyperuricaemia, dyskalaemia and their links with cardiovascular disease. He leads several national studies funded by the Health Research Board (HRB) that examine the burden, progression of CKD, and the impact of CKD and AKI in health systems. More recently, his research programme has been funded to tackle the challenges associated with transitioning of care from advanced CKD to dialysis and explore sex disparities in CKD.

Professor Stack leads the development of the Irish National Kidney Disease Surveillance System, and co-investigator the US CKD Surveillance System with the University of Michigan and University California San Francisco (UCSF). Concurrently, with international partners, he is active in global clinical trials that investigate the impact of novel therapies for the prevention of kidney disease.

Professor Stack serves on the editorial board for major journals and sits on several national and international steering committees and advisory groups. His work has been funded by the American Heart Association (AHA), National Institutes of Health (NIH), Irish Health Research Board (HRB), and Enterprise Ireland (EI). He also serves as a reviewer for Wellcome Trust UK, Chief Scientist Office for Research Scotland, and National Institutes of Health.

Publications

Clancy CC, Browne LD, Gilligan R, Blake O, Stack AG. Prevalence of anaemia, iron, and vitamin deficiencies in the Irish health system. BJGP Open. 2023 Dec 13:BJGPO.2023.0126. doi: 10.3399/BJGPO.2023.0126. Epub ahead of print. PMID: 38092441.

 

Walsh C, Browne LD, Gilligan R, Galvin R, Glynn L, Walsh C, Stack AG. Impact of serum sodium concentrations, and effect modifiers on mortality in the Irish Health System. BMC Nephrol. 2023 Jul 6;24(1):203. doi: 10.1186/s12882-023-03251-w. PMID: 37407935; PMCID: PMC10324141

 

Macdougall IC, Ponikowski P, Stack AG, Wheeler DC, Anker SD, Butler J, Filippatos G, Göhring UM, Kirwan BA, Kumpeson V, Metra M, Rosano G, Ruschitzka F, van der Meer P, Wächter S, Jankowska EA. Ferric Carboxymaltose in Iron-Deficient Patients with Hospitalized Heart Failure and Reduced Kidney Function. Clin J Am Soc Nephrol. 2023 Sep 1;18(9):1124-1134. doi: 10.2215/CJN.0000000000000223. Epub 2023 Jun 29. PMID: 37382961; PMCID: PMC10564367.

 

Maguire IC, Browne LD, Dawood M, Leahy F, Ryan MC, White E, O'Sullivan A, O'Sullivan L, Stack AG. Differential Impact of Central Venous Catheters versus Arteriovenous Fistulae on Quality of Life among Irish Haemodialysis Patients. Kidney360. 2022 Mar 4;3(6):1065-1072. doi: 10.34067/KID.0006622021. PMID: 35845328; PMCID: PMC9255886.

 

Heerspink HJL, Stack AG, Terkeltaub R, Greene TA, Inker LA, Bjursell M, Perl S, Rikte T, Erlandsson F, Perkovic V. Rationale, design, demographics and baseline characteristics of the randomized, controlled, Phase 2b SAPPHIRE study of verinurad plus allopurinol in patients with chronic kidney disease and hyperuricaemia. Nephrol Dial Transplant. 2022 Jul 26;37(8):1461-1471. doi: 10.1093/ndt/gfab237. PMID: 34383954; PMCID: PMC9317164.