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Dr. Pat Kiely

Dr Pat Kiely is Senior Lecturer in Molecular Sciences and Principal Investigator of the Laboratory of Cellular and Molecular Biology in the Graduate Entry Medical School, University of Limerick. He is a member of the Health Research Institute, the Bernal Institute and a member of the 4i Centre for Interventions in Infection, Inflammation and Immunology (University of Limerick). The research emphasis in Dr Kiely’s laboratory is on deciphering the localized and transient signalling events which occur in cells during migration. To help achieve their goals, his group work closely with several research groups and clinicians and are using a series of complementary and synergistic cellular and molecular approaches and novel technologies to investigate how protein complexes are assembled in signalling pathways. His group have a specific interest in defining the signalling pathways regulating cell migration in colon cancer and in understanding how the extracellular matrix contributes to the development and progression of cancer.

The research emphasis in my laboratory is on deciphering the localized and transient signalling events which occur in cells during migration. We have a specific interest in defining the signalling pathways regulating cell migration in breast cancer and colon cancer. We are using a series of complementary and synergistic cellular and molecular approaches and novel technologies to investigate how protein complexes are assembled in signalling pathways during this process. Understanding the molecular mechanisms that regulate cell migration is of important intellectual and clinical interest, and we believe this work may reveal fresh approaches to target cancer as well as developmental and neurodegenerative diseases.

For a short video describing my work, please click on the link below.

https://www.youtube.com/watch?v=EspgPwviGUU

Publication Record: 

For an up to date list of recent publications, please click on the link below.

https://www.ncbi.nlm.nih.gov/pubmed/?term=Kiely+PA