Welcome to 4i

UL's Centre for Interventions in Infection, Inflammation & Immunity (4i) brings together like-minded researchers from across the University and distributed clinical campuses, in addition to the General Practice network affiliated with UL School of Medicine. The Centre provides the vision, sense of identity, support and guidance that enables existing and new researchers as they continue to contribute to medical knowledge.


Researchers from this Centre determine the effectiveness of interventions, and establish the safety, cost-effectiveness & acceptability of those interventions. These interventions focus on translational research and on the integration of biomedical and clinical research in primary and secondary care.


Our clinical and laboratory programmes develop new insights into the underlying mechanisms of host-pathogen interactions and develop novel strategies to prevent or treat infectious diseases.


The acute phase response, to deal with tissue damage and infection, is diverse. Our researchers investigate processes ranging from acute inflammation associated with microbial infection of the skin through to chronic processes involved in atherosclerosis, respiratory, arthritis, and gastrointestinal diseases.


Clinical and laboratory investigations of specific and non-specific components of the host (human) response to challenges.


Latest News

Latest News
three women in lab coats examining test tube
14 Feb 2023

Latest Funding

Researchers at the Graduate Entry Medical School, University of Limerick (GEMS) have been awarded €500,000 funding to develop a new percussion device that helps remove mucus from the airways and will greatly improve the quality of life for cystic fibrosis patients.
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event image for sylester o halloran symposium
14 Feb 2023

Sylvester O Halloran Surgical Scientific Symposium

The annual Sylvester O'Halloran Surgical Scientific Symposium, named in his honour, was started in 1992 by the late Mr Peter Delaney.  The symposium is now conducted over three days and two locations, both GEMS on the UL campus and the CERC building in UHL.
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Photo of Colum Dunne
13 Feb 2023

Researcher Spotlight

Prof Colum Dunne - Member of Executive Management Committee
Director of Research, School of Medicine, University of Limerick
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