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Dr. Tien Teng Ong

Bio

Dr. Tien Teng Ong is currently a scientist at ICES, Singapore. He was born in Singapore in 1979 and received his B.Sc.(Hons.) and Ph.D. degrees from the National University of Singapore (2004) and University of South Florida (2011) respectively. His graduate research focused on the crystal engineering of molecular and ionic pharmaceutical materials under the supervision of Prof. Michael J. Zaworotko. From 2011 to 2013, he was a senior research scientist at Albany Molecular Research, Inc., where his work involved the preclinical development of investigational new drugs, particularly solid form screening for polymorphs, salts and cocrystals. Since 2013, he is seconded to GSK Evidence-Based Formulation group to focus on the clinical development of combination drugs in emerging markets research and development.

He is the co-author of five peer-reviewed publications and co-inventor of two patents. Research interests include crystal engineering, solid form screening and secondary pharmaceutical processing. Current work is focused on formulation development of immediate release solid oral dosage forms.

Publications

  1. Ong, T. T.; Kavuru, P.; Nguyen, T.; Cantwell, R.; Wojtas, Ł.; Zaworotko, M. J., 2:1 Cocrystals of Homochiral and Achiral Amino Acid Zwitterions with Li+ Salts: Water-Stable Zeolitic and Diamondoid Metal–Organic Materials. Journal of the American Chemical Society 2011, 133 (24), 9224-9227
  2. Kavuru, P.; Aboarayes, D.; Arora, K. K.; Clarke, H. D.; Kennedy, A.; Marshall, L.; Ong, T. T.; Perman, J.; Pujari, T.; Wojtas, Ł.; Zaworotko, M. J., Hierarchy of Supramolecular Synthons: Persistent Hydrogen Bonds Between Carboxylates and Weakly Acidic Hydroxyl Moieties in Cocrystals of Zwitterions. Crystal Growth & Design 2010, 10 (8), 3568-3584
  3. Clarke, H. D.; Arora, K. K.; Bass, H.; Kavuru, P.; Ong, T. T.; Pujari, T.; Wojtas, L.; Zaworotko, M. J., Structure−Stability Relationships in Cocrystal Hydrates: Does the Promiscuity of Water Make Crystalline Hydrates the Nemesis of Crystal Engineering? Crystal Growth & Design 2010, 10 (5), 2152-2167
  4. Tian, L.; Yep, L. Y.; Ong, T. T.; Yi, J.; Ding, J.; Vittal, J. J., Synthesis of NiS and MnS Nanocrystals from the Molecular Precursors (TMEDA)M(SC{O}C6H5)2 (M = Ni, Mn). Crystal Growth & Design 2008, 9 (1), 352-357
  5. Alshahateet, S. F.; Ong, T. T.; Bishop, R.; Kooli, F.; Messali, M., A Dinitrodiphenyldiquinoline Host for Selective Inclusion of Polar Guests. Crystal Growth & Design 2006, 6 (7), 1676-1683

Education

B.Sc.(Hons.), National University of Singapore, Singapore, 2004 Ph.D., University of South Florida, Tampa, Florida, USA, 2011