Martina O'Keeffe

Harnedy-Rothwell P.;McLaughlin C.;O'Keeffe M.;Le Gouic A.;Allsopp P.;McSorley E.;Sharkey S.;Whooley J.;McGovern B.;O'Harte F.;FitzGerald R. (2020) Identification and characterisation of peptides from a boarfish (Capros aper) protein hydrolysate displaying in vitro dipeptidyl peptidase-IV (DPP-IV) inhibitory and insulinotropic activity. Food Research International

O'Sullivan, SM;O'Callaghan, YC;O'Keeffe, MB;FitzGerald, RJ;O'Brien, NM (2019) Immunomodulatory activity of 5 kDa permeate fractions of casein hydrolysates generated using a range of enzymes in Jurkat T cells and RAW264.7 macrophages. OXFORD : ELSEVIER SCI LTD International Dairy Journal :9-17

Maria Cermeno;Julianne Stack;Paul R. Tobin;Martina B. O'Keeffe;Pádraigín A. Harnedy;Dagmar B. Stengel;Richard J. FitzGerald; (2019) Peptide identification from a Porphyra dioica protein hydrolysate with antioxidant, angiotensin converting enzyme and dipeptidyl peptidase IV inhibitory activities. Food & Function

Cermeño M.;Connolly A.;O'Keeffe M.;Flynn C.;Alashi A.;Aluko R.;FitzGerald R. (2019) Identification of bioactive peptides from brewers’ spent grain and contribution of Leu/Ile to bioactive potency. Journal Of Functional Foods

Harnedy, PA;Parthsarathy, V;McLaughlin, CM;O'Keeffe, MB;Allsopp, PJ;McSorley, EM;O'Harte, FPM;FitzGerald, RJ (2018) Atlantic salmon (Salmo salar) co-product-derived protein hydrolysates: A source of antidiabetic peptides. AMSTERDAM : ELSEVIER SCIENCE BV Food Research International :598-606

O'Keeffe, MB,FitzGerald, RJ (2018) Whey protein hydrolysate induced modulation of endothelial cell gene expression. Journal Of Functional Foods :102-109

Harnedy, PA,Parthsarathy, V,McLaughlin, CM,O'Keeffe, MB,Allsopp, PJ,McSorley, EM,O'Harte, FPM,FitzGerald, RJ (2018) Blue whiting (Micromesistius poutassou) muscle protein hydrolysate with in vitro and in vivo antidiabetic properties. Journal Of Functional Foods :137-145

O'Keeffe, MB,Norris, R,Alashi, MA,Aluko, RE,FitzGerald, RJ (2017) Peptide identification in a porcine gelatin prolyl endoproteinase hydrolysate with angiotensin converting enzyme (ACE) inhibitory and hypotensive activity. Journal Of Functional Foods :77-88

Connolly, A,O'Keeffe, MB,Nongonierma, AB,Piggott, CO,FitzGerald, RJ (2017) Isolation of peptides from a novel brewers spent grain protein isolate with potential to modulate glycaemic response. International Journal Of Food Science And Technology :146-153

Sae-Leaw, T,Karnjanapratum, S,O'Callaghan, YC,O'Keeffe, MB,FitzGerald, RJ,O'Brien, NM,Benjakul, S (2017) Purification and identification of antioxidant peptides from gelatin hydrolysate of seabass skin. Journal Of Food Biochemistry

Harnedy, PA,O'Keeffe, MB,FitzGerald, RJ (2017) Fractionation and identification of antioxidant peptides from an enzymatically hydrolysed Palmaria palmata protein isolate. Food Research International :416-422

Neves, AC,Harnedy, PA,O'Keeffe, MB,FitzGerald, RJ (2017) Bioactive peptides from Atlantic salmon (Salmo salar) with angiotensin converting enzyme and dipeptidyl peptidase IV inhibitory, and antioxidant activities. Food chemistry :396-405

Neves, AC,Harnedy, PA,O'Keeffe, MB,Alashi, MA,Aluko, RE,FitzGerald, RJ (2017) Peptide identification in a salmon gelatin hydrolysate with antihypertensive, dipeptidyl peptidase IV inhibitory and antioxidant activities. Food Research International :112-120

Karnjanapratum, S.;O'Callaghan, Y.C.;Benjakul, S.;O'Keeffe, M.B.;FitzGerald, R.J.;O'Brien, N.M.; (2017) Purification and identification of antioxidant peptides from gelatin hydrolysates of unicorn leatherjacket skin. Italian Journal Of Food Science

O'Keeffe, MB,Conesa, C,FitzGerald, RJ (2017) Identification of angiotensin converting enzyme inhibitory and antioxidant peptides in a whey protein concentrate hydrolysate produced at semi-pilot scale. International Journal Of Food Science And Technology :1751-1759

Thanasak Sae‐Leaw, Supatra Karnjanapratum, Yvonne C O'Callaghan, Martina B O'Keeffe, Richard J FitzGerald, Nora M O'Brien, Soottawat Benjakul (2016) Purification and identification of antioxidant peptides from gelatin hydrolysate of seabass skin. Journal Of Food Biochemistry

Connolly, A,O'Keeffe, MB,Piggott, CO,Nongonierma, AB,FitzGerald, RJ (2015) Generation and identification of angiotensin converting enzyme (ACE) inhibitory peptides from a brewers' spent grain protein isolate. Food Chemistry :64-71

Norris, R,O'Keeffe, MB,Poyarkov, A,FitzGerald, RJ (2015) Peptide identification and angiotensin converting enzyme (ACE) inhibitory activity in prolyl endoproteinase digests of bovine alpha(s)-casein. Food chemistry :210-217

Kleekayai, T, Harnedy, PA, O'Keeffe, MB, Poyarkov, AA, CunhaNeves, A, Suntornsuk, W, FitzGerald, RJ (2015) Extraction of antioxidant and ACE inhibitory peptides from Thai traditional fermented shrimp pastes. Food Chemistry :441-447

O'Keeffe, MB,FitzGerald, RJ (2015) Identification of short peptide sequences in complex milk protein hydrolysates. Food chemistry :140-146

Guo, LD,Harnedy, PA,O'Keeffe, MB,Zhang, L,Li, BF,Hou, H,FitzGerald, RJ (2015) Fractionation and identification of Alaska pollock skin collagen-derived mineral chelating peptides. Food chemistry :536-542

Harnedy PA, O'Keeffe MB, FitzGerald RJ (2015) Purification and identification of dipeptidyl peptidase (DPP) IV inhibitory peptides from the macroalga Palmaria palmata.. Food Chemistry :400-406

O'Keeffe, MB,FitzGerald, RJ (2014) Antioxidant effects of enzymatic hydrolysates of whey protein concentrate on cultured human endothelial cells. International Dairy Journal :128-135

Di Pierro, G,O'Keeffe, MB,Poyarkov, A,Lomolino, G,FitzGerald, RJ (2014) Antioxidant activity of bovine casein hydrolysates produced by Ficus carica L.-derived proteinase. Food Chemistry :305-311

Norris, R,Poyarkov, A,O'Keeffe, MB,FitzGerald, RJ (2014) Characterisation of the hydrolytic specificity of Aspergillus niger derived prolyl endoproteinase on bovine beta-casein and determination of ACE inhibitory activity. Food Chemistry :29-36

Kalyankar P, Zhu Y, O'Keeffe M, O'Cuinn G, FitzGerald RJ. (2013) Substrate specificity of glutamyl endopeptidase (GE): hydrolysis studies with a bovine α-casein preparation.. Food Chemistry :501-512

O'Keeffe, MB; Devlin, AH; Burns, AJ; Gardiner, TA; Logan, ID; Hirst, DG; McKeown, SR (2008) Investigation of pericytes, hypoxia, and vascularity in bladder tumors: Association with clinical outcomes. Oncology Research :93-101

O'Keeffe MB, Reid HM, Kinsella BT (2008) Agonist-dependent internalization and trafficking of the human prostacyclin receptor: a direct role for Rab5a GTPase.. Biochimica et biophysica acta :1914-1928

Wikstrom K, Reid HM, Hill M, English KA, O'Keeffe MB, Kimbembe CC, Kinsella BT (2008) Recycling of the human prostacyclin receptor is regulated through a direct interaction with Rab11a GTPase.. Cellular signalling :2332-2346

Kelley-Hickie LP, O'Keeffe MB, Reid HM, Kinsella BT (2007) Homologous desensitization of signalling by the alpha (alpha) isoform of the human thromboxane A2 receptor: a specific role for nitric oxide signalling.. Biochimica et biophysica acta :970-989

Coyle AT, O'Keeffe MB, Kinsella BT (2005) 15-deoxy Delta12,14-prostaglandin J2 suppresses transcription by promoter 3 of the human thromboxane A2 receptor gene through peroxisome proliferator-activated receptor gamma in human erythroleukemia cells.. The FEBS journal :4754-4773

Worthington, J.;Robson, T.;O'Keeffe, M.;Hirst, D.G.; (2002) Tumour cell radiosensitization using constitutive (CMV) and radiation inducible (WAF1) promoters to drive the iNOS gene: A novel suicide gene therapy. Gene Therapy