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Emeritus Prof. Michael Larvin

Research Interests

Pancreatic disease: acute and chronic pancreatitis, pancreatic cancer. Obesity including bariatric surgery. GI surgery including minimally invasive procedures and flexible endoscopy. Clinical trialling and systematic reviews. Surgical training and educational technology.

Teaching Interests

Basic medical sciences, post-graduate surgical training, multiprofessional learning, high-fidelity simulation, e-learning.

Professional Activities

Committee

  • 2012 An Bord Altranais agus Cnáimhseachais na hÉireann, Nominated to represent Irish Education 3rd sector - December 2012.

Publications

Peer Reviewed Journals

2013

Effect of colon cancer and surgical resection on skeletal muscle mitochondrial enzyme activity in colon cancer patients: a pilot study
Phillips, B. E.,Smith, K.,Liptrot, S.,Atherton, P. J.,Varadhan, K.,Rennie, M. J.,Larvin, M.,Lund, J. N.,Williams, J. P.
(2013) Effect of colon cancer and surgical resection on skeletal muscle mitochondrial enzyme activity in colon cancer patients: a pilot study
In J Cachexia Sarcopenia Muscle; School of Graduate Entry Medicine and Health, University of Nottingham, Royal Derby Hospital, Derby, :
DOI: 10.1007/s13539-012-0073-7

2013

Effect of colon cancer and surgical resection on skeletal muscle mitochondrial enzyme activity in colon cancer patients: a pilot study.
Phillips BE, Smith K, Liptrot S, Atherton PJ, Varadhan K, Rennie MJ, Larvin M, Lund JN, Williams JP
(2013) Effect of colon cancer and surgical resection on skeletal muscle mitochondrial enzyme activity in colon cancer patients: a pilot study.
In Journal of cachexia, sarcopenia and muscle; pp. 71-77
DOI: 10.1007/s13539-012-0073-7
[ULIR]

2012

Effect of tumor burden and subsequent surgical resection on skeletal muscle mass and protein turnover in colorectal cancer patients.
Williams JP, Phillips BE, Smith K, Atherton PJ, Rankin D, Selby AL, Liptrot S, Lund J, Larvin M, Rennie MJ
(2012) Effect of tumor burden and subsequent surgical resection on skeletal muscle mass and protein turnover in colorectal cancer patients.
In The American journal of clinical nutrition; pp. 1064-1070
DOI: 10.3945/ajcn.112.045708

2012

Weight loss following laparoscopic band replacement/repositioning for failed primary laparoscopic adjustable gastric band procedure
Menakuru, S.,Ahmed, J.,Larvin, M.,Leeder, P.
(2012) Weight loss following laparoscopic band replacement/repositioning for failed primary laparoscopic adjustable gastric band procedure
In British Journal of Surgery;

2012

MicroRNAs: Relevant Tools for a Colorectal Surgeon?
Peacock, O.,Lee, A. C.,Larvin, M.,Tufarelli, C.,Lund, J. N.
(2012) MicroRNAs: Relevant Tools for a Colorectal Surgeon?
In World Journal of Surgery;
DOI: 10.1007/s00268-012-1603-3

2012

Cannabinoids mediate opposing effects on inflammation-induced intestinal permeability
Alhamoruni A, Wright KL, Larvin M, O'Sullivan SE.
(2012) Cannabinoids mediate opposing effects on inflammation-induced intestinal permeability
In British Journal Of Pharmacology; pp. 2598-2610
DOI: 10.1111/j.1476-5381.2011.01589.x

2012

MicroRNAs: relevant tools for a colorectal surgeon?
Peacock, O.,Lee, A. C.,Larvin, M.,Tufarelli, C.,Lund, J. N.
(2012) MicroRNAs: relevant tools for a colorectal surgeon?
In World J Surg; Division of Surgery, School of Graduate Entry Medicine & Health, University of Nottingham, Royal Der :

2012

Cannabinoids mediate opposing effects on inflammation-induced intestinal permeability
Alhamoruni, A.,Wright, K. L.,Larvin, M.,O'Sullivan, S. E.
(2012) Cannabinoids mediate opposing effects on inflammation-induced intestinal permeability
In Br J Pharmacol; School of Graduate Entry Medicine & Health, Derby City General Hospital, University of Nottingham, D :

2012

MicroRNAs: relevant tools for a colorectal surgeon?
Peacock O, Lee AC, Larvin M, Tufarelli C, Lund JN
(2012) MicroRNAs: relevant tools for a colorectal surgeon?
In World Journal Of Surgery; pp. 1881-1892
DOI: 10.1007/s00268-012-1603-3

2012

Effect of tumor burden and subsequent surgical resection on skeletal muscle mass and protein turnover in colorectal cancer patients
Williams, J. P.,Phillips, B. E.,Smith, K.,Atherton, P. J.,Rankin, D.,Selby, A. L.,Liptrot, S.,Lund, J.,Larvin, M.,Rennie, M. J.
(2012) Effect of tumor burden and subsequent surgical resection on skeletal muscle mass and protein turnover in colorectal cancer patients
In Am J Clin Nutr; School of Graduate Entry Medicine and Health, University of Nottingham, Derby, United Kingdom. john. :
DOI: 10.3945/ajcn.112.045708

2012

Sarcopenia, dynapenia, and the impact of advancing age on human skeletal muscle size and strength; a quantitative review
Mitchell, W. K.,Williams, J.,Atherton, P.,Larvin, M.,Lund, J.,Narici, M.
(2012) Sarcopenia, dynapenia, and the impact of advancing age on human skeletal muscle size and strength; a quantitative review
In Front Physiol; Division of Surgery, School of Postgraduate Entry Medicine and Health, University of Nottingham Derb : pp. 260-
DOI: 10.3389/fphys.2012.00260
[ULIR]

2011

Increased BMI does not adversely affect vascular function measured in vitro in obese patients
Kwak, H. C.,Larvin, M.,O'Sullivan, S.
(2011) Increased BMI does not adversely affect vascular function measured in vitro in obese patients
In British Journal of Surgery;

2011

Knockdown of microRNA-21 inhibits proliferation and increases cell death by targeting programmed cell death 4 (PDCD4) in pancreatic ductal adenocarcinoma
Bhatti, I.,Lee, A.,James, V.,Hall, R. I.,Lund, J. N.,Tufarelli, C.,Lobo, D. N.,Larvin, M.
(2011) Knockdown of microRNA-21 inhibits proliferation and increases cell death by targeting programmed cell death 4 (PDCD4) in pancreatic ductal adenocarcinoma
In J Gastrointest Surg; Division of Surgery, School of Graduate Entry Medicine and Health, University of Nottingham Medical :

2011

Upregulated Micro-RNA 21 targets PDCD4 inhibiting pancreatic cancer proliferation
Bhatti, I.,Lee, A.,Tufarelli, C.,Lund, J. N.,Hall, R. I.,Lobo, D. N.,Larvin, M.
(2011) Upregulated Micro-RNA 21 targets PDCD4 inhibiting pancreatic cancer proliferation
In British Journal of Surgery;

2011

Knockdown of microRNA-21 Inhibits Proliferation and Increases Cell Death by Targeting Programmed Cell Death 4 (PDCD4) in Pancreatic Ductal Adenocarcinoma
Bhatti, I.,Lee, A.,James, V.,Hall, R. I.,Lund, J. N.,Tufarelli, C.,Lobo, D. N.,Larvin, M.
(2011) Knockdown of microRNA-21 Inhibits Proliferation and Increases Cell Death by Targeting Programmed Cell Death 4 (PDCD4) in Pancreatic Ductal Adenocarcinoma
In Journal of Gastrointestinal Surgery;
DOI: 10.1007/s11605-010-1381-x

2011

Knockdown of microRNA-21 inhibits proliferation and increases cell death by targeting programmed cell death 4 (PDCD4) in pancreatic ductal adenocarcinoma.
Bhatti I, Lee A, James V, Hall RI, Lund JN, Tufarelli C, Lobo DN, Larvin M
(2011) Knockdown of microRNA-21 inhibits proliferation and increases cell death by targeting programmed cell death 4 (PDCD4) in pancreatic ductal adenocarcinoma.
In Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract; pp. 199-208
DOI: 10.1007/s11605-010-1381-x

2011

An unusual cause of dysuria
Kwak, H. C.,Tan, G.,Rickers, L.,Leeder, P.,Larvin, M.
(2011) An unusual cause of dysuria
In Ann R Coll Surg Engl; School of Graduate Entry Medicine and Health, Royal Derby Hospital, Derby, UK. hye-chung.kwak@nottin :

2010

TRANSIENT RESPONSE TO BOTULINUM TOXIN INJECTION PREDICTS THE MEDIUM-TERM OUTCOME AFTER ENDOSCOPIC SPHINCTEROTOMY IN TYPE 2/3 SPHINCTER OF ODDI DYSFUNCTION
Austin, A. S.,Wheeler, K.,Larvin, M.,Hall, R.,Freeman, J.
(2010) TRANSIENT RESPONSE TO BOTULINUM TOXIN INJECTION PREDICTS THE MEDIUM-TERM OUTCOME AFTER ENDOSCOPIC SPHINCTEROTOMY IN TYPE 2/3 SPHINCTER OF ODDI DYSFUNCTION
In Gut;
DOI: 10.1136/gut.2009.209015m

2010

Antibacterial prophylaxis does not prevent mortality nor infection of pancreatic necrosis in acute pancreatitis
Villatoro, E.,Hill, P.,Mulla, M.,Hall, R. I.,Larvin, M.
(2010) Antibacterial prophylaxis does not prevent mortality nor infection of pancreatic necrosis in acute pancreatitis
In British Journal of Surgery;

2010

Preoperative hematologic markers as independent predictors of prognosis in resected pancreatic ductal adenocarcinoma: neutrophil-lymphocyte versus platelet-lymphocyte ratio
Bhatti, I.,Peacock, O.,Lloyd, G.,Larvin, M.,Hall, R. I.
(2010) Preoperative hematologic markers as independent predictors of prognosis in resected pancreatic ductal adenocarcinoma: neutrophil-lymphocyte versus platelet-lymphocyte ratio
In Am J Surg; University of Nottingham Medical School, Derby City General Hospital, UK. imran.bhatti@nottingham.ac :
DOI: 10.1016/j.amjsurg.2009.08.041

2010

A pre-operative elevated neutrophil: lymphocyte ratio does not predict survival from oesophageal cancer resection
Rashid, F.,Waraich, N.,Bhatti, I.,Saha, S.,Khan, R. N.,Ahmed, J.,Leeder, P. C.,Larvin, M.,Iftikhar, S. Y.
(2010) A pre-operative elevated neutrophil: lymphocyte ratio does not predict survival from oesophageal cancer resection
In World J Surg Oncol; Royal Derby Hospital, Uttoxeter Road, Derby DE22 3NE, UK. farhan.rashid@nottingham.ac.uk : pp. 1-
DOI: 10.1186/1477-7819-8-1
[ULIR]

2010

Lymph node ratio versus number of affected lymph nodes as predictors of survival for resected pancreatic adenocarcinoma
Bhatti, I.,Peacock, O.,Awan, A. K.,Semeraro, D.,Larvin, M.,Hall, R. I.
(2010) Lymph node ratio versus number of affected lymph nodes as predictors of survival for resected pancreatic adenocarcinoma
In World J Surg; Division of Surgery, School of Graduate Entry Medicine and Health, University of Nottingham Medical :
DOI: 10.1007/s00268-009-0336-4

2010

Upregulated Micro-RNA 21 Targets PDCD4 and Inhibits Proliferation in Pancreatic Cancer
Bhatti, I.,Lee, V.,Lee, A.,Lund, J. N.,Hall, R. I.,Tufarelli, C.,Lobo, D.,Larvin, M.
(2010) Upregulated Micro-RNA 21 Targets PDCD4 and Inhibits Proliferation in Pancreatic Cancer
In Pancreas;

2010

A potential new biomarker and treatment for oesophageal cancer
Rashid, F.,Warren, A.,Lee, A.,Leeder, P. C.,Larvin, M.,Khan, R.,Iftikhar, S. Y.
(2010) A potential new biomarker and treatment for oesophageal cancer
In British Journal of Surgery;

2010

A review article on gastric volvulus: a challenge to diagnosis and management
Rashid, F.,Thangarajah, T.,Mulvey, D.,Larvin, M.,Iftikhar, S. Y.
(2010) A review article on gastric volvulus: a challenge to diagnosis and management
In Int J Surg; Division of GI Surgery, University of Nottingham, Graduate Entry Medical School, Royal Derby Hospita :

2010

Pharmacological effects of cannabinoids on the Caco-2 cell culture model of intestinal permeability
Alhamoruni, A.,Lee, A. C.,Wright, K. L.,Larvin, M.,O'Sullivan, S. E.
(2010) Pharmacological effects of cannabinoids on the Caco-2 cell culture model of intestinal permeability
In J Pharmacol Exp Ther; School of Graduate Entry Medicine and Health, Royal Derby Hospital, University of Nottingham, Nottin :

2010

A phase Ib/IIa trial to evaluate the CCK2 receptor antagonist Z-360 in combination with gemcitabine in patients with advanced pancreatic cancer
Meyer, T.,Caplin, M. E.,Palmer, D. H.,Valle, J. W.,Larvin, M.,Waters, J. S.,Coxon, F.,Borbath, I.,Peeters, M.,Nagano, E.,Kato, H.
(2010) A phase Ib/IIa trial to evaluate the CCK2 receptor antagonist Z-360 in combination with gemcitabine in patients with advanced pancreatic cancer
In Eur J Cancer; UCL, London, UK. t.meyer@ucl.ac.uk :
DOI: 10.1016/j.ejca.2009.11.004

2010

A review article on gastric volvulus: A challenge to diagnosis and management
Rashid, F.,Thangarajah, T.,Mulvey, D.,Larvin, M.,Iftikhar, S. Y.
(2010) A review article on gastric volvulus: A challenge to diagnosis and management
In International Journal of Surgery;
DOI: 10.1016/j.ijsu.2009.11.002

2010

Modulation of intestinal permeability by cannabinoids, cytokines and cannabinoid receptor antagonists in a novel in vitro model
Alhamoruni, A.,Lund, J. N.,Larvin, M.,O'Sullivan, S.
(2010) Modulation of intestinal permeability by cannabinoids, cytokines and cannabinoid receptor antagonists in a novel in vitro model
In British Journal of Surgery;

2010

Antibiotic therapy for prophylaxis against infection of pancreatic necrosis in acute pancreatitis
Villatoro, E.,Mulla, M.,Larvin, M.
(2010) Antibiotic therapy for prophylaxis against infection of pancreatic necrosis in acute pancreatitis
In Cochrane Database Syst Rev; Academic Division of Surgery, School of Graduate Entry Medicine, University of Nottingham, Derby Cit :
DOI: 10.1002/14651858.CD002941.pub3
[ULIR]

2010

Pharmacological Effects of Cannabinoids on the Caco-2 Cell Culture Model of Intestinal Permeability
Alhamoruni, A.,Lee, A. C.,Wright, K. L.,Larvin, M.,O'Sullivan, S. E.
(2010) Pharmacological Effects of Cannabinoids on the Caco-2 Cell Culture Model of Intestinal Permeability
In Journal of Pharmacology and Experimental Therapeutics;
DOI: 10.1124/jpet.110.168237

2009

E-Learning in surgical education and training
Larvin, M.
(2009) E-Learning in surgical education and training
In Anz Journal of Surgery;
DOI: 10.1111/j.1445-2197.2008.04828.x

2009

Small RNA: a large contributor to carcinogenesis?
Bhatti, I.,Lee, A.,Lund, J.,Larvin, M.
(2009) Small RNA: a large contributor to carcinogenesis?
In J Gastrointest Surg; Division of Surgery, School of Graduate Entry Medicine and Health, University of Nottingham Medical :

2009

Small RNA: A Large Contributor to Carcinogenesis?
Bhatti, I.,Lee, A.,Lund, J.,Larvin, M.
(2009) Small RNA: A Large Contributor to Carcinogenesis?
In Journal of Gastrointestinal Surgery;
DOI: 10.1007/s11605-009-0887-6

2009

Urinary iFABP: An Instant Predictor of Outcome From Acute Pancreatitis?
Villatoro, E.,Silk, R.,Mulla, M.,Hall, R.,Larvin, M.
(2009) Urinary iFABP: An Instant Predictor of Outcome From Acute Pancreatitis?
In Pancreas;

2009

E-learning in surgical education and training
Larvin, M.
(2009) E-learning in surgical education and training
In ANZ J Surg; Academic Division of Surgery, School of Graduate Entry Medicine and Health, University of Nottingham :

2009

Antibacterial Prophylaxis in Pancreatic Necrosis: The Final Word?
Villatoro, E.,Mulla, M.,Hall, R.,Larvin, M.
(2009) Antibacterial Prophylaxis in Pancreatic Necrosis: The Final Word?
In Pancreas;

2008

A phase IB/IIA, multicentre, randomised, double-blind placebo controlled study to evaluate the safety and pharmacokinetics of Z-360 in subjects with unresectable advanced pancreatic cancer in combination with gemcitabine
Meyer, T.,Caplin, M.,Palmer, D.,Valle, J. W.,Larvin, M.,Waters, J.,Coxon, F.,Borbath, I.,Peeters, M.,Nagano, E.,Kato, H.
(2008) A phase IB/IIA, multicentre, randomised, double-blind placebo controlled study to evaluate the safety and pharmacokinetics of Z-360 in subjects with unresectable advanced pancreatic cancer in combination with gemcitabine
In Journal of Clinical Oncology;

2008

Management of infected pancreatic necrosis
Larvin, M.
(2008) Management of infected pancreatic necrosis
In Curr Gastroenterol Rep; Division of Surgery, School of Graduate Entry Medicine and Health, University of Nottingham at Derby :

2008

Antibacterial prophylaxis does not prevent infection of pancreatic necrosis in acute pancreatitis
Villatoro, E. A.,Mulla, M. G.,Hall, R. I.,Larvin, M.
(2008) Antibacterial prophylaxis does not prevent infection of pancreatic necrosis in acute pancreatitis
In Gastroenterology;

2008

Which pre-operative factors predict adequate weight loss following laparoscopic gastric band insertion?
Mulla, M. G.,Singh, R.,Clarke, D.,Rickers, L.,Cresswell, K.,Parry, L.,Leeder, P. C.,Larvin, M.,Tan, G. D.
(2008) Which pre-operative factors predict adequate weight loss following laparoscopic gastric band insertion?
In International Journal of Obesity;

2008

The SPINK1 N34S variant is associated with acute pancreatitis
O'Reilly, D. A.,Witt, H.,Rahman, S. H.,Schulz, H. U.,Sargen, K.,Kage, A.,Cartmell, M. T.,Landt, O.,Larvin, M.,Demaine, A. G.,McMahon, M. J.,Becker, M.,Kingsnorth, A. N.
(2008) The SPINK1 N34S variant is associated with acute pancreatitis
In Eur J Gastroenterol Hepatol; Department of Surgery, Derriford Hospital, University of Plymouth, Plymouth, UK. doreilly@doctors.or :

2008

The SPINK1 N34S variant is associated with acute pancreatitis
O'Reilly, D. A.,Witt, H.,Rahman, S. H.,Schulz, H. U.,Sargen, K.,Kage, A.,Cartmell, M. T.,Landt, F.,Larvin, M.,Demaine, A. G.,McMahon, M. J.,Becker, M.,Kingsnorth, A. N.
(2008) The SPINK1 N34S variant is associated with acute pancreatitis
In European Journal of Gastroenterology & Hepatology;

2008

Diagnosis of biliary adenomyomatosis
Mulla, M. G.,Srivastava, V.,Hopper, I.,Klein, J.,Larvin, M.,Hall, R.
(2008) Diagnosis of biliary adenomyomatosis
In European Surgery-Acta Chirurgica Austriaca;

2007

Large bowel obstruction due to sesame seed bezoar: a case report
Shaw, A. G.,Peacock, O.,Lund, J. N.,Tierney, G. M.,Larvin, M.,Speake, W.
(2007) Large bowel obstruction due to sesame seed bezoar: a case report
In J Med Case Rep; Department of Gastrointestinal Surgery, University of Nottingham, Derby, UK. drshaw@doctors.net.uk. : pp. 159-
[ULIR]

2006

Antibiotic therapy for prophylaxis against infection of pancreatic necrosis in acute pancreatitis
Villatoro, E.,Bassi, C.,Larvin, M.
(2006) Antibiotic therapy for prophylaxis against infection of pancreatic necrosis in acute pancreatitis
In Cochrane Database Syst Rev; University of Nottingham, Division of GI Surgery, University of Nottingham School of Medicine, Clini :

2005

Clinical presentation and delayed treatment of cholangitis in older people
Rahman, S. H.,Larvin, M.,McMahon, M. J.,Thompson, D.
(2005) Clinical presentation and delayed treatment of cholangitis in older people
In Dig Dis Sci; Academic Unit of Surgery, The General Infrimary, Leeds, UK. zakrahman@lineone.net :

2005

Genetic polymorphisms of GSTT1, GSTM1, GSTP1, MnSOD, and catalase in nonhereditary chronic pancreatitis: evidence of xenobiotic stress and impaired antioxidant capacity
Rahman, S. H.,Nanny, C.,Ibrahim, K.,O'Reilly, D.,Larvin, M.,Kingsnorth, A. J.,McMahon, M. J.
(2005) Genetic polymorphisms of GSTT1, GSTM1, GSTP1, MnSOD, and catalase in nonhereditary chronic pancreatitis: evidence of xenobiotic stress and impaired antioxidant capacity
In Dig Dis Sci; Academic Unit of Surgery, The General Infirmary, Great George Street, Leeds LS1 3EA, UK. zak-rahman@ :

2004

Association of antioxidant enzyme gene polymorphisms and glutathione status with severe acute pancreatitis
Rahman, S. H.,Ibrahim, K.,Larvin, M.,Kingsnorth, A.,McMahon, M. J.
(2004) Association of antioxidant enzyme gene polymorphisms and glutathione status with severe acute pancreatitis
In Gastroenterology; Academic Unit of Surgery, University of Leeds, 6th Floor Wellcome Wing, The General Infirmary, Great :

2004

Soluble CD14 receptor expression and monocyte heterogeneity but not the C-260T CD14 genotype are associated with severe acute pancreatitis
Rahman, S. H.,Salter, G.,Holmfield, J. H.,Larvin, M.,McMahon, M. J.
(2004) Soluble CD14 receptor expression and monocyte heterogeneity but not the C-260T CD14 genotype are associated with severe acute pancreatitis
In Crit Care Med; Academic Unit of Surgery, University of Leeds, General Infirmary, Leeds, West Yorkshire, UK. :

2004

Soluble CD14 receptor expression and monocyte heterogeneity but not the C-260T CD14 genotype are associated with severe acute pancreatitis
Rahman, S. H.,Salter, G.,Holmfield, J. H. M.,Larvin, M.,McMahon, M. J.
(2004) Soluble CD14 receptor expression and monocyte heterogeneity but not the C-260T CD14 genotype are associated with severe acute pancreatitis
In Critical Care Medicine;

2003

Micropuncture cholecystectomy vs conventional laparoscopic cholecystectomy: a randomized controlled trial
Ainslie, W. G. and Catton, J. A. and Davides, D. and Dexter, S. and Gibson, J. and Larvin, M. and McMahon, M. J. and Moore, M. and Smith, S. and Vezakis, A.
(2003) Micropuncture cholecystectomy vs conventional laparoscopic cholecystectomy: a randomized controlled trial
In Surg Endosc; pp. 766-72

2003

Diagnostic accuracy of endoscopic ultrasound-guided fine-needle aspiration in patients with presumed pancreatic cancer - Discussion
Way, L. W.,Raut, C. P.,Larvin, M.,Kirkwood, K. S.,Yeo, C. J.,Drebin, J. A.
(2003) Diagnostic accuracy of endoscopic ultrasound-guided fine-needle aspiration in patients with presumed pancreatic cancer - Discussion
In Journal of Gastrointestinal Surgery;

2003

Calcitonin precursors: early markers of gut barrier dysfunction in patients with acute pancreatitis
Ammori, B. J.,Becker, K. L.,Kite, P.,Snider, R. H.,Nylén, E. S.,White, J. C.,Barclay, G. R.,Larvin, M.,McMahon, M. J.
(2003) Calcitonin precursors: early markers of gut barrier dysfunction in patients with acute pancreatitis
In Pancreas; Division of Surgery at the University of Leeds, The General Infirmary, Leeds, UK. Bammori@aol.com :

2003

Increased nitric oxide excretion in patients with severe acute pancreatitis: evidence of an endotoxin mediated inflammatory response?
Rahman, S. H.,Ammori, B. J.,Larvin, M.,McMahon, M. J.
(2003) Increased nitric oxide excretion in patients with severe acute pancreatitis: evidence of an endotoxin mediated inflammatory response?
In Gut; Academic Unit of Surgery, the General Infirmary, Leeds, UK. zak-rahman@lineone.net :

2003

Day-case laparoscopic cholecystectomy: a prospective evaluation of a 6-year experience
Ammori, B. J.,Davides, D.,Vezakis, A.,Martin, I. G.,Larvin, M.,Smith, S.,Gibson, J. S.,McMahon, M. J.
(2003) Day-case laparoscopic cholecystectomy: a prospective evaluation of a 6-year experience
In J Hepatobiliary Pancreat Surg; Leeds Institute for Minimally Invasive Therapy and Division of Surgery, University of Leeds, Leeds, :

2003

Micropuncture cholecystectomy vs conventional laparoscopic cholecystectomy: a randomized controlled trial
Ainslie, W. G.,Catton, J. A.,Davides, D.,Dexter, S.,Gibson, J.,Larvin, M.,McMahon, M. J.,Moore, M.,Smith, S.,Vezakis, A.
(2003) Micropuncture cholecystectomy vs conventional laparoscopic cholecystectomy: a randomized controlled trial
In Surg Endosc; The Academic Unit of Surgery, The University of Leeds and the Leeds Institute for Minimally Invasive :

2003

Laparoscopic cholecystectomy - Are patients with biliary pancreatitis at increased operative risk?
Ammori, B. J.,Davides, D.,Vezakis, A.,Larvin, M.,McMahon, M. J.
(2003) Laparoscopic cholecystectomy - Are patients with biliary pancreatitis at increased operative risk?
In Surgical Endoscopy and Other Interventional Techniques;

2003

Hypocalcemia in patients with acute pancreatitis: a putative role for systemic endotoxin exposure
Ammori, B. J.,Barclay, G. R.,Larvin, M.,McMahon, M. J.
(2003) Hypocalcemia in patients with acute pancreatitis: a putative role for systemic endotoxin exposure
In Pancreas; Division of Surgery, The University of Leeds, and Center for Digestive Diseases, The General Infirma :

2003

Laparoscopic cholecystectomy: are patients with biliary pancreatitis at increased operative risk?
Ammori, B. J.,Davides, D.,Vezakis, A.,Larvin, M.,McMahon, M. J.
(2003) Laparoscopic cholecystectomy: are patients with biliary pancreatitis at increased operative risk?
In Surg Endosc; Division of Surgery, University of Leeds, United Kingdom. :

2003

Intestinal hypoperfusion contributes to gut barrier failure in severe acute pancreatitis
Rahman, S. H.,Ammori, B. J.,Holmfield, J.,Larvin, M.,McMahon, M. J.
(2003) Intestinal hypoperfusion contributes to gut barrier failure in severe acute pancreatitis
In J Gastrointest Surg; Academic Department of Surgery, The General Infirmary at Leeds, Leeds, United Kingdom. :

2003

Micropuncture cholecystectomy vs conventional laparoscopic cholecystectomy - A randomized controlled trial
Ainslie, W. G.,Catton, J. A.,Davides, D.,Dexter, S.,Gibson, J.,Larvin, M.,McMahon, M. J.,Moore, M.,Smith, S.,Vezakis, A.
(2003) Micropuncture cholecystectomy vs conventional laparoscopic cholecystectomy - A randomized controlled trial
In Surgical Endoscopy and Other Interventional Techniques;

2003

Micropuncture cholecystectomy vs conventional laparoscopic cholecystectomy - A randomized controlled trial
Ainslie, W. G.,Catton, J. A.,Davides, D.,Dexter, S.,Gibson, J.,Larvin, M.,McMahon, M. J.,Moore, M.,Smith, S.,Vezakis, A.
(2003) Micropuncture cholecystectomy vs conventional laparoscopic cholecystectomy - A randomized controlled trial
In Surgical Endoscopy and Other Interventional Techniques;

2003

Hypocalcemia in patients with acute pancreatitis: A putative role for systemic endotoxin exposure
Ammori, B. J.,Barclay, G. R.,Larvin, M.,McMahon, M. J.
(2003) Hypocalcemia in patients with acute pancreatitis: A putative role for systemic endotoxin exposure
In Pancreas;

2003

Antibiotic therapy for prophylaxis against infection of pancreatic necrosis in acute pancreatitis
Bassi, C.,Larvin, M.,Villatoro, E.
(2003) Antibiotic therapy for prophylaxis against infection of pancreatic necrosis in acute pancreatitis
In Cochrane Database Syst Rev;

2003

Laparoscopic management of pseudocysts of the pancreas
Ainslie, W. G.,Maude, K. M.,Catton, J. A.,Ammori, B. J.,Larvin, M.,McMahon, M. J.
(2003) Laparoscopic management of pseudocysts of the pancreas
In British Journal of Surgery;

2003

Calcitonin precursors in the prediction of severity of acute pancreatitis on the day of admission
Ammori, B. J.,Becker, K. L.,Kite, P.,Snider, R. H.,Nylén, E. S.,White, J. C.,Larvin, M.,McMahon, M. J.
(2003) Calcitonin precursors in the prediction of severity of acute pancreatitis on the day of admission
In Br J Surg; Division of Surgery, University of Leeds and Centre for Digestive Diseases, The General Infirmary, L :

2002

Down-regulation of hepatic function, the acute phase response and severe gallstone pancreatitis
Rahman, S. H.,Larvin, M.,McMahon, M. J.
(2002) Down-regulation of hepatic function, the acute phase response and severe gallstone pancreatitis
In British Journal of Surgery;

2002

Does pneumatic dilatation affect the outcome of laparoscopic cardiomyotomy?
Dolan, K.,Zafirellis, K.,Fountoulakis, A.,Martin, I. G.,Dexter, S. P.,Larvin, M.,McMahon, M. J.
(2002) Does pneumatic dilatation affect the outcome of laparoscopic cardiomyotomy?
In Surg Endosc; Division of Surgery, Leeds Institute for Minimally Invasive Therapy, The General Infirmary at Leeds, :

2002

Ischaemia-reperfusion injury, gut macromolecular permeability and severe acute pancreatitis
Rahman, S. H.,James, A. M.,Ammori, B.,Larvin, M.,McMahon, M. J.
(2002) Ischaemia-reperfusion injury, gut macromolecular permeability and severe acute pancreatitis
In British Journal of Surgery;

2002

Intraoperative cholangiography during laparoscopic cholecystectomy - The author replies
McMahon, M. J.,Vezakis, A.,Davides, D.,Ammori, B. J.,Martin, I. G.,Larvin, M.
(2002) Intraoperative cholangiography during laparoscopic cholecystectomy - The author replies
In Surgical Endoscopy and Other Interventional Techniques;

2002

Calcitonin precursors (CTpr): early markers of gut barrier dysfunction in patients with acute pancreatitis
Ammori, B. J.,Becker, K. L.,Kite, P.,Snider, R. H.,Nylen, E. S.,White, J. C.,Barclay, G. R.,Larvin, M.,McMahon, M. J.
(2002) Calcitonin precursors (CTpr): early markers of gut barrier dysfunction in patients with acute pancreatitis
In British Journal of Surgery;

2002

Altered intestinal morphology and immunity in patients with acute necrotizing pancreatitis
Ammori, B. J.,Cairns, A.,Dixon, M. F.,Larvin, M.,McMahon, M. J.
(2002) Altered intestinal morphology and immunity in patients with acute necrotizing pancreatitis
In J Hepatobiliary Pancreat Surg; Division of Surgery, The University of Leeds, Leeds, UK. :

2002

Early changes in intestinal permeability to macromolecules predict outcome in patients with acute pancreatitis: a comparative study with C-reactive protein and the APACHE II scoring system
Ammori, B.,Leeder, P. C.,King, Rfgj,Martin, I. G.,Larvin, M.,McMahon, M. J.
(2002) Early changes in intestinal permeability to macromolecules predict outcome in patients with acute pancreatitis: a comparative study with C-reactive protein and the APACHE II scoring system
In British Journal of Surgery;

2002

Cyst-gastrostomy via the cyst: an unusual laparoscopic approach
Ainslie, W. G.,Larvin, M.,McMahon, M. J.
(2002) Cyst-gastrostomy via the cyst: an unusual laparoscopic approach
In Endoscopy; Leeds Institute for Minimally Invasive Therapy (LIMIT), and Academic Unit of Surgery, The General In : pp. 432-

2001

Double blind, randomised, placebo controlled study of a platelet activating factor antagonist, lexipafant, in the treatment and prevention of organ failure in predicted severe acute pancreatitis
Johnson, C. D.,Kingsnorth, A. N.,Imrie, C. W.,McMahon, M. J.,Neoptolemos, J. P.,McKay, C.,Toh, S. K.,Skaife, P.,Leeder, P. C.,Wilson, P.,Larvin, M.,Curtis, L. D.
(2001) Double blind, randomised, placebo controlled study of a platelet activating factor antagonist, lexipafant, in the treatment and prevention of organ failure in predicted severe acute pancreatitis
In Gut; University Surgical Unit, F Level, Centre Block, Southampton General Hospital, Tremona Road, Southam :
[ULIR]

2001

A rapid and systematic review of the clinical effectiveness and cost-effectiveness of gemcitabine for the treatment of pancreatic cancer
Ward, S.,Morris, E.,Bansback, N.,Calvert, N.,Crellin, A.,Forman, D.,Larvin, M.,Radstone, D.
(2001) A rapid and systematic review of the clinical effectiveness and cost-effectiveness of gemcitabine for the treatment of pancreatic cancer
In Health Technol Assess; School of Health and Related Research, University of Sheffield, UK. :
[ULIR]

2001

Laparoscopic cholecystectomy in morbidly obese patients
Ammori, B. J.,Vezakis, A.,Davides, D.,Martin, I. G.,Larvin, M.,McMahon, M. J.
(2001) Laparoscopic cholecystectomy in morbidly obese patients
In Surg Endosc; Leeds Institute for Minimally Invasive Therapy (LIMIT), University Department of Surgery, The Genera :

2001

Elective laparoscopic cholecystectomy: preoperative prediction of duration of surgery
Ammori, B. J.,Larvin, M.,McMahon, M. J.
(2001) Elective laparoscopic cholecystectomy: preoperative prediction of duration of surgery
In Surg Endosc; Leeds Institute for Minimally Invasive Therapy (LIMIT), Wellcome Wing, The General Infirmary, Great :

2000

Successful laparoscopic rescue of an impacted lithotriptor basket from the common bile duct
Ainslie, W.,Reed, J.,Larvin, M.,McMahon, M. J.
(2000) Successful laparoscopic rescue of an impacted lithotriptor basket from the common bile duct
In Endoscopy; Leeds Institute for Minimally Invasive Therapy, and the University Division of Surgery, The General :

2000

Laparoscopic treatment of Mirizzi syndrome
Vezakis, A.,Davides, D.,Birbas, K.,Ammori, B. J.,Larvin, M.,McMahon, M. J.
(2000) Laparoscopic treatment of Mirizzi syndrome
In Surg Laparosc Endosc Percutan Tech; Leeds Institute for Minimally Invasive Therapy, The Centre for Digestive Diseases, The General Infir :

2000

Routine vs "on demand" postoperative ERCP for small bile duct calculi detected at intraoperative cholangiography. Clinical evaluation and cost analysis
Ammori, B. J.,Birbas, K.,Davides, D.,Vezakis, A.,Larvin, M.,McMahon, M. J.
(2000) Routine vs "on demand" postoperative ERCP for small bile duct calculi detected at intraoperative cholangiography. Clinical evaluation and cost analysis
In Surg Endosc; Division of Surgery, University of Leeds and Leeds Institute for Minimally Invasive Therapy, The Gen :

2000

Intraoperative cholangiography during laparoscopic cholecystectomy
Vezakis, A.,Davides, D.,Ammori, B. J.,Martin, I. G.,Larvin, M.,McMahon, M. J.
(2000) Intraoperative cholangiography during laparoscopic cholecystectomy
In Surg Endosc; Leeds Institute for Minimally Invasive Therapy, General Infirmary and University Division of Surgery :

2000

Relaparoscopy for the detection and treatment of complications of laparoscopic cholecystectomy
Dexter, S. P.,Miller, G. V.,Davides, D.,Martin, I. G.,Sue Ling, H. M.,Sagar, P. M.,Larvin, M.,McMahon, M. J.
(2000) Relaparoscopy for the detection and treatment of complications of laparoscopic cholecystectomy
In Am J Surg; Leeds Institute for Minimally Invasive Therapy, Centre for Digestive Diseases, and the University of :

2000

Liver retraction techniques for laparoscopic cholecystectomy
Ainslie, W. B.,Larvin, M.,Martin, I. G.,McMahon, M. J.
(2000) Liver retraction techniques for laparoscopic cholecystectomy
In Surg Endosc;

1999

Laparoscopic surgery combined with preservation of the spleen for distal pancreatic tumors
Vezakis, A.,Davides, D.,Larvin, M.,McMahon, M. J.
(1999) Laparoscopic surgery combined with preservation of the spleen for distal pancreatic tumors
In Surg Endosc; Leeds Institute for Minimally Invasive Surgery, and the Centre for Digestive Diseases, the General I :

1999

Micropuncture laparoscopic cholecystectomy
Davides, D.,Dexter, S. P.,Vezakis, A.,Larvin, M.,Moran, P.,McMahon, M. J.
(1999) Micropuncture laparoscopic cholecystectomy
In Surg Endosc; Leeds Institute for Minimally Invasive Therapy, Centre for Digestive Diseases and the University Div :

1999

Randomized comparison between low-pressure laparoscopic cholecystectomy and gasless laparoscopic cholecystectomy
Vezakis, A. and Davides, D. and Gibson, J. S. and Moore, M. R. and Shah, H. and Larvin, M. and McMahon, M. J.
(1999) Randomized comparison between low-pressure laparoscopic cholecystectomy and gasless laparoscopic cholecystectomy
In Surg Endosc; pp. 890-3

1999

Randomized comparison between low-pressure laparoscopic cholecystectomy and gasless laparoscopic cholecystectomy
Vezakis, A.,Davides, D.,Gibson, J. S.,Moore, M. R.,Shah, H.,Larvin, M.,McMahon, M. J.
(1999) Randomized comparison between low-pressure laparoscopic cholecystectomy and gasless laparoscopic cholecystectomy
In Surg Endosc; Leeds Institute for Minimally Invasive Therapy, Academic Unit of Surgery, The General Infirmary at L :

1999

Early increase in intestinal permeability in patients with severe acute pancreatitis: correlation with endotoxemia, organ failure, and mortality
Ammori, B. J.,Leeder, P. C.,King, R. F.,Barclay, G. R.,Martin, I. G.,Larvin, M.,McMahon, M. J.
(1999) Early increase in intestinal permeability in patients with severe acute pancreatitis: correlation with endotoxemia, organ failure, and mortality
In J Gastrointest Surg; Academic Surgical Unit, Division of Surgery, The University of Leeds and Centre for Digestive Diseas :

1999

Randomized comparison between low-pressure laparoscopic cholecystectomy and gasless laparoscopic cholecystectomy
Vezakis, A. and Davides, D. and Gibson, J. S. and Moore, M. R. and Shah, H. and Larvin, M. and McMahon, M. J.
(1999) Randomized comparison between low-pressure laparoscopic cholecystectomy and gasless laparoscopic cholecystectomy
In Surg Endosc; pp. 890-3

1998

Laparoscopic cholecystectomy after pancreatic debridement
Vezakis, A.,Dexter, S. P.,Martin, I. G.,Larvin, M.,McMahon, M. J.
(1998) Laparoscopic cholecystectomy after pancreatic debridement
In Surg Endosc; Leeds Institute for Minimally Invasive Therapy, The Centre for Digestive Diseases, The General Infir :

1997

Assessment of severity and prognosis in acute pancreatitis
Larvin, M.
(1997) Assessment of severity and prognosis in acute pancreatitis
In Eur J Gastroenterol Hepatol; Academic Surgical Unit and Centre for Digestive Diseases, The General Infirmary, Leeds, UK. :

1997

Fatal hepatic air embolism following ERCP
Kennedy, C.,Larvin, M.,Linsell, J.
(1997) Fatal hepatic air embolism following ERCP
In Gastrointest Endosc; Department of Radiology, Lewisham Hospital, London, United Kingdom. :

1997

T2-weighted and dynamic enhanced MRI in acute pancreatitis: comparison with contrast enhanced CT
Ward, J.,Chalmers, A. G.,Guthrie, A. J.,Larvin, M.,Robinson, P. J.
(1997) T2-weighted and dynamic enhanced MRI in acute pancreatitis: comparison with contrast enhanced CT
In Clin Radiol; Department of Radiology, St James's University Hospital, Leeds, UK. :

1997

When should you suspect pancreatitis?
Larvin, M.
(1997) When should you suspect pancreatitis?
In Practitioner; Academic Surgical Unit, General Infirmary, Leeds. :

1996

Circulating mediators in acute pancreatitis as predictors of severity
Larvin, M.
(1996) Circulating mediators in acute pancreatitis as predictors of severity
In Scand J Gastroenterol Suppl; LIMIT, Leeds General Infirmary, UK. :

1994

Control of colonic variceal haemorrhage by long-term octreotide administration
Walters, A. M.,Larvin, M.,Sadek, S. A.
(1994) Control of colonic variceal haemorrhage by long-term octreotide administration
In Br J Surg; Academic Unit of Surgery, St Jame's University Hospital, Leeds, UK. : pp. 290-

1993

Impaired mononuclear phagocyte function in patients with severe acute pancreatitis: evidence from studies of plasma clearance of trypsin and monocyte phagocytosis
Larvin, M.,Alexander, D. J.,Switala, S. F.,McMahon, M. J.
(1993) Impaired mononuclear phagocyte function in patients with severe acute pancreatitis: evidence from studies of plasma clearance of trypsin and monocyte phagocytosis
In Dig Dis Sci; University Department of Surgery, General Infirmary, Leeds, UK. :

1990

Gastric volvulus: a rare cause of hyperamylasaemia
Williams, L.,Lansdown, M. R.,Larvin, M.,Ward, D. C.
(1990) Gastric volvulus: a rare cause of hyperamylasaemia
In Br J Clin Pract; Department of Surgery, Huddersfield Royal Infirmary. :

1990

Proteolytic degradation of human recombinant proinsulin/insulin by sera from acute pancreatitis patients and complete inhibition by Eglin-C
Lau, P. P.,Van Handel, M.,Larvin, M.,McMahon, M. J.,Geokas, M. C.
(1990) Proteolytic degradation of human recombinant proinsulin/insulin by sera from acute pancreatitis patients and complete inhibition by Eglin-C
In Pancreas; Enzymology Research Laboratory, Veterans Administration Medical Center, Martinez, California. :

1990

Dynamic contrast enhanced computed tomography: a precise technique for identifying and localising pancreatic necrosis
Larvin, M.,Chalmers, A. G.,McMahon, M. J.
(1990) Dynamic contrast enhanced computed tomography: a precise technique for identifying and localising pancreatic necrosis
In BMJ; University Department of Surgery, General Infirmary, Leeds. :
[ULIR]

1989

Debridement and closed cavity irrigation for the treatment of pancreatic necrosis
Larvin, M.,Chalmers, A. G.,Robinson, P. J.,McMahon, M. J.
(1989) Debridement and closed cavity irrigation for the treatment of pancreatic necrosis
In Br J Surg; University Department of Surgery, General Infirmary, Leeds, UK. :

1989

APACHE-II score for assessment and monitoring of acute pancreatitis
Larvin, M.,McMahon, M. J.
(1989) APACHE-II score for assessment and monitoring of acute pancreatitis
In Lancet; University Department of Surgery, General Infirmary, Leeds. :

1988

Hyperamylasaemia
Larvin, M.,McMahon, M. J.
(1988) Hyperamylasaemia
In J R Coll Surg Edinb; pp. 107-

1988

Intra-peritoneal aprotinin therapy for acute pancreatitis. Preliminary pharmacodynamic studies
Larvin, M.,Mayer, A. D.,McMahon, M. J.,Müller-Esterl, W.,Fritz, H.
(1988) Intra-peritoneal aprotinin therapy for acute pancreatitis. Preliminary pharmacodynamic studies
In Biol Chem Hoppe Seyler; University Department of Surgery, General Infirmary, Leeds, U.K. :

1988

Plasmapheresis: a rational treatment for fulminant acute pancreatitis?
Larvin, M.,Lansdown, M. R.,McMahon, M. J.,Chalmers, A. G.,Turney, J. H.,Brownjohn, A. M.
(1988) Plasmapheresis: a rational treatment for fulminant acute pancreatitis?
In BMJ; General Infirmary, Leeds. :

1988

Plasmapheresis and fulminant acute pancreatitis?
Larvin, M.,Lansdown, M. R.,McMahon, M. J.,Chalmer, A. G.,Turney, J. H.,Brownjohn, A. M.
(1988) Plasmapheresis and fulminant acute pancreatitis?
In BMJ; pp. 1332-

1987

Fatigue fracture of a femoral sliding compression screw-plate device after bone union
Amis, A. A.,Bromage, J. D.,Larvin, M.
(1987) Fatigue fracture of a femoral sliding compression screw-plate device after bone union
In Biomaterials;

Other Journals

2012

Effect of colon cancer and surgical resection on skeletal muscle mitochondrial enzyme activity in colon cancer patients: a pilot study
Phillips B, Smith K, Liptrot S, Atherton P, Varadhan K, Rennie MJ, Larvin M, Lund JN, Williams JP
(2012) Effect of colon cancer and surgical resection on skeletal muscle mitochondrial enzyme activity in colon cancer patients: a pilot study
In Journal of Cachexia, Sarcopenia and Muscle;
DOI: 10.1007/s13539-012-0073-7

2012

Sarcopenia, dynapenia, and the impact of advancing age on human skeletal muscle size and strength; a quantitative review.
Mitchell WK, Williams J, Atherton P, Larvin M, Lund J, Narici M.
(2012) Sarcopenia, dynapenia, and the impact of advancing age on human skeletal muscle size and strength; a quantitative review.
In Frontiers in Physiology; pp. 1-18
DOI: 10.3389/fphys.2012.00260