Skip to main content

Dr Andrew Stewart



My research centres on the applications and development of high-resolution electron microscope techniques, in particular diffraction based electron microscopy, including:
3D-Electron Diffraction Techniques (3DED) Including MicroED
4 dimensional scanning transmission electron microscopy (4D-STEM)
Large Angle Rocking Beam Electron Diffraction (LARBED)
Digital-Electron Diffraction (D-ED)
With their application to characterisation electron beam sensitive materials such as pharmaceuticals organics, and in situ electron experiments.

Our technique development work includes the application of Machine Learning and Artificial Intelligence to electron microscopy, with a view to enabling TEM to become a more Metrological science, with high reproducibility and quantitative data for
measurements of the atomic and electronic structure of materials.

We develop methods and software which adheres to the FAIR principles, and enables TEM to become and more open science.

Research Interests

  • Transmission Electron Microscopy
  • Electron Diffraction
  • 3D Electron Diffraction
  • Nano Crystallography
  • Polymorphism
  • Automation of TEM
  • Phase Inverse Problems
  • In Situ TEM
  • CryoEM
  • Machine Learning
  • Metrology
  • Open Data Formats
  • Energy Dispersive X-ray spectroscopy (EDS)
  • 4D Scanning Transmission Electron Microscopy
  • Ptychography

Professional Activities


  • 2003 University of Glasgow - PhD


  • Cornell University - Postdoctoral Researcher
  • Stony Brook University - Postdoctoral Researcher
  • University of Oxford - Research Fellow
  • Johannes Gutenberg University Mainz - Postdoctoral Researcher
  • University of Patras - Senior Research Fellow
  • University of Limerick - Senior Research Fellow


  • Member, Institute of Physics
  • member, Royal Microscopy Society

Research Collaborators

  • A. Cavallo - Joint Publication - Certema -Italy
  • A. Gurlo - Joint Publication - Darmstadt University of Technology -Germany
  • Andras Kovacs - Joint Publication - Forschungszentrum Jülich -Germany
  • Christine Leidinger - Joint Publication - Forschungszentrum Jülich -Germany
  • Demie Kepatsogloub - Joint Publication - STFC Daresbury Laboratory -England
  • Ericvan Genderen - Joint Publication - Leiden University -Netherlands
  • Ervin Mehmedovic - Joint Publication - University of Duisburg Essen -Germany
  • F. Karavassili - Joint Publication - University of Patras -Greece
  • G. Lezzi - Joint Publication - University of Chieti-Pescara -Italy
  • G Bromiley - Joint Publication - University of Edinburgh -Scotland
  • Gustav Bihlmayer - Joint Publication - Forschungszentrum Jülich -Germany
  • H- J. Kleebe - Joint Publication - Darmstadt University of Technology -Germany
  • Hartmut Wiggers - Joint Publication - University of Duisburg Essen -Germany
  • I. Margiolaki - Joint Publication - University of Patras -Greece
  • Igor Nederlof - Joint Publication - Leiden University -Netherlands
  • Jan Pieter Abrahams - Joint Publication - Leiden University -Netherlands
  • Jonathan Wright - Joint Publication - ESRF - the European Synchrotron Radiation Facility -France
  • K. C. Barentsen - Joint Publication - Leiden University -Netherlands
  • M. Schwarz - Joint Publication - Darmstadt University of Technology -Germany
  • Maged Bekheet - Joint Publication - Darmstadt University of Technology -Germany
  • Martha Escarcega - Joint Publication - Institute of Chemical Research of Catalonia (ICIQ) -Spain
  • Martina Luysberg - Joint Publication - Forschungszentrum Jülich -Germany
  • Max Clabbers - Joint Publication - Leiden University -Netherlands
  • N. S. Pannu - Joint Publication - Leiden University -Netherlands
  • P artha Das - Joint Publication - Nanomegas SPRL -Belgium
  • P. Kroll - Joint Publication - Darmstadt University of Technology -Germany
  • Pengxiang Xu - Joint Publication - Forschungszentrum Jülich -Germany
  • Q. Portillo - Joint Publication - University of Barcelona -Spain
  • Quentin Rassmase - Joint Publication - STFC Daresbury Laboratory -England
  • Rafal E. Dunin- Borkowski - Joint Publication - Forschungszentrum Jülich -Germany
  • Reinhard Carius - Joint Publication - Forschungszentrum Jülich -Germany
  • Richard Beanland - External Examiner - University of Warwick -England
  • Robert Imlau - Joint Publication - Forschungszentrum Jülich -Germany
  • S. Lauterbach - Joint Publication - Darmstadt University of Technology -Germany
  • Stavros Nicolopoulos - Joint Publication - Nanomegas SPRL -Belgium
  • Tamir Gonen - Outgoing Visitor - Howard Hughes Medical Institute -USA
  • Tim Gruene - Joint Publication - Paul Scherrer Institute -Switzerland
  • Ute Kolb - Joint Publication - Johannes Gutenberg University of Mainz -Germany


Peer Reviewed Journal


Dissolution of Indomethacin Crystals into a Polymer Melt: Role of Diffusion and Fragmentation
Moseson D.;Parker A.;Gilpin C.;Stewart A.;Beaudoin S.;Taylor L.
Crystal Growth & Design DOI: 10.1021/acs.cgd.9b00200


MRCZ - A file format for cryo-TEM data with fast compression
McLeod, RA,Righetto, RD,Stewart, A,Stahlberg, H
Journal Of Structural Biology DOI: 10.1016/j.jsb.2017.11.012


Ion-beam modification of 2-D materials - single implant atom analysis via annular dark-field electron microscopy
Bangert, U,Stewart, A,O'Connell, E,Courtney, E,Ramasse, Q,Kepaptsoglou, D,Hofsass, H,Anioni, J,Tu, JS,Kardynal, B
Ultramicroscopy DOI: 10.1016/j.ultramic.2016.12.011


Ab initio structure determination of nanocrystals of organic pharmaceutical compounds by electron diffraction at room temperature using a Timepix quantum area direct electron detector
van Genderen, E,Clabbers, MTB,Das, PP,Stewart, A,Nederlof, I,Barentsen, KC,Portillo, Q,Pannu, NS,Nicolopoulos, S,Gruene, T,Abrahams, JP
Acta Crystallographica A-Foundation And Advances DOI: 10.1107/S2053273315022500


Structural and electronic properties of beta-FeSi2 nanoparticles: The role of stacking fault domains
Imlau, R,Kovacs, A,Mehmedovic, E,Xu, PX,Stewart, AA,Leidinger, C,Dunin-Borkowski, RE,Bihlmayer, G,Wiggers, H,Carius, R,Kolb, U,Luysberg, M
Physical Review B DOI: ARTN 054104


Structural and electronic properties of β - 2 nanoparticles: The role of stacking fault domains
Imlau R.;Kovács A.;Mehmedovic E.;Xu P.;Stewart A.;Leidinger C.;Dunin-Borkowski R.;Bihlmayer G.;Wiggers H.;Carius R.;Kolb U.;Luysberg M.
Physical Review B - Condensed Matter And Materials Physics DOI: 10.1103/PhysRevB.89.054104