Assoc. Prof. Michael Walsh

Biography

My research activity focuses on an improved understanding of the host response to the treatment of vascular diseases. My primary area of research is focused on vascular disease properties and how such properties can be leveraged for improved medical device design. My secondary area of research investigates how disease caused by vascular surgical interventions (intimal hyperplasia) is instigated/mediated by hemodynamics. Elucidating the role of diseased tissue in device performance is a crucial step towards the understanding of how surgical treatments lead to disease formation and also how treatments can be improved to minimise intimal hyperplasia. My former post-doctoral researchers are all working in Irish industry as are 13 of 20 PhD graduates. Five other PhD graduates are all pursuing academic careers at institutions such as Georgia Institute of Technology, Edinburgh University, University of Pittsburgh, Erasmus Medical Centre, Rotterdam and the University of Limerick. I have published 74 peer-reviewed journal papers and 8 book chapters. I have 4 granted patents, 2 in review and a spin-out company, Class Medical, established in 2014.My research activity focuses on an improved understanding of the host response to the treatment of vascular diseases. My primary area of research is focused on vascular disease properties and how such properties can be leveraged for improved medical device design. My secondary area of research investigates how disease caused by vascular surgical interventions (intimal hyperplasia) is instigated/mediated by hemodynamics. Elucidating the role of diseased tissue in device performance is a crucial step towards the understanding of how surgical treatments lead to disease formation and also how treatments can be improved to minimise intimal hyperplasia. My former post-doctoral researchers are all working in Irish industry as are 13 of 20 PhD graduates. Five other PhD graduates are all pursuing academic careers at institutions such as Georgia Institute of Technology, Edinburgh University, University of Pittsburgh, Erasmus Medical Centre, Rotterdam and the University of Limerick. I have published 74 peer-reviewed journal papers and 8 book chapters. I have 4 granted patents, 2 in review and a spin-out company, Class Medical, established in 2014.

Research Interests

Research Interests: Cardiovascular Hemodynamics, Arteriovenous Access, Human diseased soft tissue characterisation

Professional Activities

Committee

2007 Biomedical Engineering Division, Engineers Ireland,
2006 American Society of Mechanical Engineers,

Employment

2007 University of Limerick - Course Director, Biomedical Engineering

Association

2006 Member, American Society of Mechanical Engineers
2005 Member, Engineers Ireland

Education

2001 University of Limerick - Ph.D.
1996 University of Limerick - B.Eng.

Patent

- The Prolong Graft for peripheral bypass surgery
- The Prolong II graft
- The Isolator Graft for Abdominal Aortic Aneurysms

Books

This author has not written any publications of this type yet.

Book Chapters

Numerical and Experimental Techniques for the Study of Biomechanics in the Arterial System

Assoc. Prof. Michael Walsh

2008

World Scientific Publishing Co.

Validated Numerical Simulations of Blood Flow Through Idealised and Realistic Graft/Artery Junctions

Assoc. Prof. Michael Walsh

2002

Comparative Analysis of Finite Element and Finite Volume Methods for Blood Flow Through a Graft-Artery Junction

Assoc. Prof. Michael Walsh

2002

Edited Books

This author has not written any publications of this type yet.

Peer Reviewed Journals

Spherical indentation of free-standing acellular extracellular matrix membranes

Assoc. Prof. Michael Walsh

Dr. Eamonn De Barra

2012

Fluid-structure interaction of a patient-specific abdominal aortic aneurysm treated with an endovascular stent-graft.

Assoc. Prof. Michael Walsh

2009

An investigation into the hemodynamic behaviour of vascular bypass grafts witha nd without the use of vein cuffs 23rd Sir peter Freyer Surgical Symposium

Assoc. Prof. Michael Walsh

1998

On the existence of an optimum end-to-side junctional geometry in peripheral bypass surgery - A computer generated study

Assoc. Prof. Michael Walsh

2003

Experimental determination of circumferential properties of fresh carotid artery plaques

Assoc. Prof. Michael Walsh

2011

An Experimental and Numerical Comparison of the Rupture Locations of an Abdominal Aortic Aneurysm

Assoc. Prof. Michael Walsh

2009

Numerical modelling of mass transport in an arterial wall with anisotropic transport properties

Assoc. Prof. Michael Walsh

2014

Computational investigations of a new prosthetic femoral-popliteal bypass graft design

Assoc. Prof. Michael Walsh

2005

Realistic Temporal Variations of Shear Stress Modulate MMP-2 and MCP-1 Expression in Arteriovenous Vascular Access

Assoc. Prof. Michael Walsh

2009

Investigation of a glottal related harmonics-to-noise ratio and spectral tilt as indicators of glottal noise in synthesized and human voice signals

Assoc. Prof. Michael Walsh

2008

A Computational Study of the Magnitude and Direction of Migration Forces in Patient-specific Abdominal Aortic Aneurysm Stent-Grafts

Assoc. Prof. Michael Walsh

2010

Identification of rupture locations in patient-specific abdominal aortic aneurysms using experimental and computational techniques

Assoc. Prof. Michael Walsh

2010

Geometrical Enhancements for Abdominal Aortic Stent-Grafts

Assoc. Prof. Michael Walsh

2008

Mechanical characterisation of unidirectional and cross-directional multilayered urinary bladder matrix (UBM) scaffolds

Assoc. Prof. Michael Walsh

2012

Vessel asymmetry as an additional diagnostic tool in the assessment of abdominal aortic aneurysms

Assoc. Prof. Michael Walsh

2009

Mass transport disturbances in the distal graft/artery junction of a peripheral bypass graft

Assoc. Prof. Michael Walsh

2005

Extracellular matrices as advanced scaffolds for vascular tissue engineering

Assoc. Prof. Michael Walsh

2009

Experimental modelling of aortic aneurysms: Novel applications of silicone rubbers

Assoc. Prof. Michael Walsh

2009

A mathematical model to predict the in vivo pulsatile drag forces acting on bifurcated stent grafts used in endovascular treatment of abdominal aortic aneurysms (AAA)

Assoc. Prof. Michael Walsh

2004

In Vitro modelling of an abdominal aortic aneurysm to determine rupture location

Assoc. Prof. Michael Walsh

2009

The mesocolon a histological and electron microscopic characterisation of the mesenteric attachment of the colon prior to and after surgical mobilization.

Assoc. Prof. Michael Walsh

Prof. Colum Dunne

2014

A New Approach to Peripheral Bypass Graft Design.

Assoc. Prof. Michael Walsh

2005

Injection-moulded models of major and minor arteries: the variability of model wall thickness owing to casting technique

Assoc. Prof. Michael Walsh

2005

Variability of Computational Fluid Dynamics Solutions for Pressure and Flow in a Giant Aneurysm: The ASME 2012 Summer Bioengineering Conference CFD Challenge

Assoc. Prof. Michael Walsh

2013

Effects of flat, parabolic and realistic steady flow inlet profiles on idealised and realistic stent graft fits through Abdominal Aortic Aneurysms (AAA)

Assoc. Prof. Michael Walsh

2006

A mathematical model to predict in vivo distraction forces acting on bifurcated stent grafts used in endovascular treatment of Abdominal Aortic Aneurysms (AAA)

Assoc. Prof. Michael Walsh

2004

An evolutionary approach to Wall Shear Stress prediction in a grafted artery

Conor Ryan

Assoc. Prof. Michael Walsh

2004

On the mechanical behaviour of carotid artery plaques: the influence of curve-fitting experimental data on numerical model results

Assoc. Prof. Michael Walsh

2013

Second Level Education and the Decline in Popularity of Engineering within an Irish Context

Assoc. Prof. Michael Walsh

Dr. Raymond Lynch

2011

On using experimentally estimated wall shear stresses to validate numerically predicted results

Assoc. Prof. Michael Walsh

2003

Engineering Silicone Rubbers for In Vitro Studies: Creating AAA Models and ILT Analogues With Physiological Properties

Assoc. Prof. Michael Walsh

2010

Altering end-to-side anastomosis junction hemodynamics: The effects of flow-splitting

Assoc. Prof. Michael Walsh

2006

An Analysis of Three Dimensional Diffusion in a Representative Arterial Wall Mass Transport Model

Assoc. Prof. Michael Walsh

2013

The Surgical Feasibility of a Novel Vascular Graft developed for the Treatment of Peripheral Arterial Disease using In Vitro Experimental Design Techniques

Assoc. Prof. Michael Walsh

2007

Influence of implant design on the method of failure for three implants designed for use in the treatment of intertrochanteric fractures: the dynamic hip screw (DHS), DHS blade and X-BOLT

Assoc. Prof. Michael Walsh

2013

Dynamic hip screw versus DHS blade A BIOMECHANICAL COMPARISON OF THE FIXATION ACHIEVED BY EACH IMPLANT IN BONE

Assoc. Prof. Michael Walsh

2011

On the potential of hydrated storage for naturally derived ECMs and associated effects on mechanical and cellular performance

Assoc. Prof. Michael Walsh

2014

Wall Shear Stresses Remain Elevated in Mature Arteriovenous Fistulas: A Case Study

Assoc. Prof. Michael Walsh

2011

Numerical modelling of Newtonian and non-Newtonian representation of blood in a distal end-to-side vascular bypass graft anastomosis

Assoc. Prof. Michael Walsh

2006

Demonstrating the Influence of Compression on Artery Wall Mass Transport

Assoc. Prof. Michael Walsh

2010

An evolutionary approach to wall shear stress prediction in a grafted artery

Conor Ryan

Assoc. Prof. Michael Walsh

2004

Mechanical, biological and structural characterization of in vitro ruptured human carotid plaque tissue

Assoc. Prof. Michael Walsh

2013

Experimental validation of convection-diffusion discretisation scheme employed for computational modelling of biological mass transport

Assoc. Prof. Michael Walsh

2010

Effects of flat, parabolic and realistic steady flow inlet profiles on idealised and realistic stent graft fits through Abdominal Aortic Aneurysms (AAA)

Assoc. Prof. Michael Walsh

2006

That hemodynamics and not material mismatch is of primary concern in bypass graft failure: An experimental argument

Assoc. Prof. Michael Walsh

2005

Wrist postures in the general population of computer users during a computer task

Assoc. Prof. Michael Walsh

2013

On reducing abnormal hemodynamics in the femoral end-to-side anastomosis: The influence of mechanical factors

Assoc. Prof. Michael Walsh

2005

Mechanical, biological and structural characterisation of in vitro ruptured human carotid plaque tissue.

Assoc. Prof. Michael Walsh

2013

Fluid-structure interaction of a patient-specific abdominal aortic aneurysm treated with an endovascular stent-graft

Assoc. Prof. Michael Walsh

2009

Improved assessment and treatment of abdominal aortic aneurysms: the use of 3D reconstructions as a surgical guidance tool in endovascular repair

Assoc. Prof. Michael Walsh

2009

3-D numerical simulation of blood flow through models of the human aorta

Assoc. Prof. Michael Walsh

2005

The Effects of Arterial Wall Remodelling on the Wall Shear Stress Distributions in Vascular Bypass Grafts ESEM Belfast May 3-5th 2001

Assoc. Prof. Michael Walsh

2001

On reducing hemodynamic factors in the femoral end-to side anastomosis: the influence of mechanical factors

Assoc. Prof. Michael Walsh

2005

Are we educating our students out of engineering?

Assoc. Prof. Michael Walsh

Dr. Raymond Lynch

2010

Dublin

Engineers Ireland

PROCEEDINGS OF THE ASME SUMMER BIOENGINEERING CONFERENCE 2008, PTS A AND B

Assoc. Prof. Michael Walsh

2009

IFMBE Proceedings

Assoc. Prof. Michael Walsh

2010

PROCEEDING OF THE ASME SUMMER BIOENGINEERING CONFERENCE - 2007

Assoc. Prof. Michael Walsh

2007

Proceedings of the ASME Summer Bioengineering Conference 2009, SBC2009

Assoc. Prof. Michael Walsh

2009

PROCEEDINGS OF THE ASME SUMMER BIOENGINEERING CONFERENCE - 2009, PT A AND B

Assoc. Prof. Michael Walsh

2009

IFMBE Proceedings

Assoc. Prof. Michael Walsh

2009

2007 AMERICAN CONTROL CONFERENCE, VOLS 1-13

Martin Hayes

Assoc. Prof. Michael Walsh

Miss. Michaela Hayes

2007

Proceedings of the 5th World Congress of Biomechanics

Assoc. Prof. Michael Walsh

2006

IET Conference Publications

Martin Hayes

Assoc. Prof. Michael Walsh

Miss. Michaela Hayes

2008

PROCEEDINGS OF THE ASME SUMMER BIOENGINEERING CONFERENCE 2008, PTS A AND B

Assoc. Prof. Michael Walsh

2009

Proceedings of the ASME Summer Bioengineering Conference 2009, SBC2009

Assoc. Prof. Michael Walsh

2009

PROCEEDINGS OF THE ASME SUMMER BIOENGINEERING CONFERENCE - 2009, PT A AND B

Assoc. Prof. Michael Walsh

2009

Proceedings of the Fifth IASTED International Conference on Biomechanics

Assoc. Prof. Michael Walsh

2007

Proceedings of the 5th World Congress of Biomechanics

Assoc. Prof. Michael Walsh

2006

Proceedings of the ASME Summer Bioengineering Conference, SBC2008

Assoc. Prof. Michael Walsh

2009

PROCEEDINGS OF THE ASME SUMMER BIOENGINEERING CONFERENCE - 2009, PT A AND B

Assoc. Prof. Michael Walsh

2009

American Society of Mechanical Engineers, Bioengineering Division (Publication) BED

Assoc. Prof. Michael Walsh

2001

PROCEEDINGS OF THE ASME SUMMER BIOENGINEERING CONFERENCE 2008, PTS A AND B

Assoc. Prof. Michael Walsh

2009

IFMBE Proceedings

Assoc. Prof. Michael Walsh

2009

PROCEEDINGS OF THE ASME SUMMER BIOENGINEERING CONFERENCE - 2009, PT A AND B

Assoc. Prof. Michael Walsh

2009

Proceedings of the ASME Summer Bioengineering Conference 2009, SBC2009

Assoc. Prof. Michael Walsh

2009

Proceedings of the 5th World Congress of Biomechanics

Assoc. Prof. Michael Walsh

2006

Proceedings of the ASME Summer Bioengineering Conference, SBC2008

Assoc. Prof. Michael Walsh

2009

PROCEEDINGS OF THE ASME SUMMER BIOENGINEERING CONFERENCE - 2009, PT A AND B

Assoc. Prof. Michael Walsh

2009

Proceedings of the ASME Summer Bioengineering Conference 2009, SBC2009

Assoc. Prof. Michael Walsh

2009

Proceedings of the 5th World Congress of Biomechanics

Assoc. Prof. Michael Walsh

2006

IFMBE Proceedings

Assoc. Prof. Michael Walsh

2009

PROCEEDINGS OF THE ASME SUMMER BIOENGINEERING CONFERENCE, 2010

Assoc. Prof. Michael Walsh

2010

Proceedings of the 2005 Summer Bioengineering Conference

Assoc. Prof. Michael Walsh

2005

Proceedings of the Fifth IASTED International Conference on Biomechanics

Assoc. Prof. Michael Walsh

2007

IFMBE Proceedings

Assoc. Prof. Michael Walsh

2009

Proceedings of the 5th World Congress of Biomechanics

Assoc. Prof. Michael Walsh

2006

Proceedings of the 2005 Summer Bioengineering Conference

Assoc. Prof. Michael Walsh

2005

Conference Contributions

This author has not written any publications of this type yet.

Published Reports

This author has not written any publications of this type yet.

Editorials

Regenerative medicine, tissue engineering and vascular surgery: twenty first century clinical challenges

Assoc. Prof. Michael Walsh

2010

Book Reviews

This author has not written any publications of this type yet.

Other Publications

EXPERIMENTAL RUPTURE OF REALISTIC ABDOMINAL AORTIC ANEURYSMS: CAN RUPTURE LOCATIONS BE PREDICTED NUMERICALLY?

Assoc. Prof. Michael Walsh

2010

Bioengineering in cardiovascular surgery Lecture to Royal Academy of Medicine of Ireland

Assoc. Prof. Michael Walsh

1998

The Mesocolon; A Histological Characterisation of the Mesenteric Attachment of The Colon

Assoc. Prof. Michael Walsh

Prof. Colum Dunne

2013

URINARY BLADDER MATRIX TUBULAR SCAFFOLDS AS A TISSUE ENGINEERED VASCULAR GRAFT

Assoc. Prof. Michael Walsh

2010

Computational Fluid Dynamics studies of Blood Flow in Vascular Grafts

Assoc. Prof. Michael Walsh

2000

The vascular potential of urinary bladder matrix an extracellular matrix material

Assoc. Prof. Michael Walsh

2013

Regenerative medicine, tissue engineering and vascular surgery: twenty first century clinical challenges

Assoc. Prof. Michael Walsh

2010

The need for guidelines for surgical techniques to increase bypass graft patency rates

Assoc. Prof. Michael Walsh

2000

EFFECTIVENESS OF STROKE PREVENTION USING EMBOLIC PROTECTION DURING CAROTID ARTERY STENTING

Assoc. Prof. Michael Walsh

2007

Blood Flow in Vascular Grafts,

Assoc. Prof. Michael Walsh

1997

HIP AND MUSCLE FORCES IN HIP REPLACEMENT SUBJECTS

Assoc. Prof. Michael Walsh

2010

Factors that affect mass transport from drug eluting stents into the artery wall

Assoc. Prof. Michael Walsh

2010

BIOMECHANICAL COMPARISON OF THE DYNAMIC HIP SCREW (DHS), THE X-BOLT AND THE DHS BLADE

Assoc. Prof. Michael Walsh

2010

X-bolt versus the dynamic hip screw (DHS): does this new design variation offer potential? A biomechanical study

Assoc. Prof. Michael Walsh

2011

STRENGTH OF ATHEROSCLEROTIC PLAQUE IN CAROTID ARTERY

Assoc. Prof. Michael Walsh

2010

PRE-CLINICAL EVALUATION OF THE PROLONG (R) VASCULAR GRAFT

Assoc. Prof. Michael Walsh

2010

ECM-Based Materials in Cardiovascular Applications: Inherent Healing Potential and Augmentation of Native Regenerative Processes

Assoc. Prof. Michael Walsh

2009

Biography

Research Interests

Professional Activities

Committee

Employment

Association

Education

Patent

Publications

Books

Book Chapters

Numerical and Experimental Techniques for the Study of Biomechanics in the Arterial System

Validated Numerical Simulations of Blood Flow Through Idealised and Realistic Graft/Artery Junctions

Comparative Analysis of Finite Element and Finite Volume Methods for Blood Flow Through a Graft-Artery Junction

Edited Books

Peer Reviewed Journals

Spherical indentation of free-standing acellular extracellular matrix membranes

Fluid-structure interaction of a patient-specific abdominal aortic aneurysm treated with an endovascular stent-graft.

An investigation into the hemodynamic behaviour of vascular bypass grafts witha nd without the use of vein cuffs 23rd Sir peter Freyer Surgical Symposium

On the existence of an optimum end-to-side junctional geometry in peripheral bypass surgery - A computer generated study

Experimental determination of circumferential properties of fresh carotid artery plaques

An Experimental and Numerical Comparison of the Rupture Locations of an Abdominal Aortic Aneurysm

Numerical modelling of mass transport in an arterial wall with anisotropic transport properties

Computational investigations of a new prosthetic femoral-popliteal bypass graft design

Realistic Temporal Variations of Shear Stress Modulate MMP-2 and MCP-1 Expression in Arteriovenous Vascular Access

Investigation of a glottal related harmonics-to-noise ratio and spectral tilt as indicators of glottal noise in synthesized and human voice signals

A Computational Study of the Magnitude and Direction of Migration Forces in Patient-specific Abdominal Aortic Aneurysm Stent-Grafts

Identification of rupture locations in patient-specific abdominal aortic aneurysms using experimental and computational techniques

Geometrical Enhancements for Abdominal Aortic Stent-Grafts

Mechanical characterisation of unidirectional and cross-directional multilayered urinary bladder matrix (UBM) scaffolds

Vessel asymmetry as an additional diagnostic tool in the assessment of abdominal aortic aneurysms

Mass transport disturbances in the distal graft/artery junction of a peripheral bypass graft

Extracellular matrices as advanced scaffolds for vascular tissue engineering

Experimental modelling of aortic aneurysms: Novel applications of silicone rubbers

A mathematical model to predict the in vivo pulsatile drag forces acting on bifurcated stent grafts used in endovascular treatment of abdominal aortic aneurysms (AAA)

In Vitro modelling of an abdominal aortic aneurysm to determine rupture location

The mesocolon  a histological and electron microscopic characterisation of the mesenteric attachment of the colon prior to and after surgical mobilization.

A New Approach to Peripheral Bypass Graft Design.

Injection-moulded models of major and minor arteries: the variability of model wall thickness owing to casting technique

Variability of Computational Fluid Dynamics Solutions for Pressure and Flow in a Giant Aneurysm: The ASME 2012 Summer Bioengineering Conference CFD Challenge

Effects of flat, parabolic and realistic steady flow inlet profiles on idealised and realistic stent graft fits through Abdominal Aortic Aneurysms (AAA)

A mathematical model to predict in vivo distraction forces acting on bifurcated stent grafts used in endovascular treatment of Abdominal Aortic Aneurysms (AAA)

An evolutionary approach to Wall Shear Stress prediction in a grafted artery

On the mechanical behaviour of carotid artery plaques: the influence of curve-fitting experimental data on numerical model results

Second Level Education and the Decline in Popularity of Engineering within an Irish Context

On using experimentally estimated wall shear stresses to validate numerically predicted results

Engineering Silicone Rubbers for In Vitro Studies: Creating AAA Models and ILT Analogues With Physiological Properties

Altering end-to-side anastomosis junction hemodynamics: The effects of flow-splitting

An Analysis of Three Dimensional Diffusion in a Representative Arterial Wall Mass Transport Model

The Surgical Feasibility of a Novel Vascular Graft developed for the Treatment of Peripheral Arterial Disease using In Vitro Experimental Design Techniques

Influence of implant design on the method of failure for three implants designed for use in the treatment of intertrochanteric fractures: the dynamic hip screw (DHS), DHS blade and X-BOLT

Dynamic hip screw versus DHS blade A BIOMECHANICAL COMPARISON OF THE FIXATION ACHIEVED BY EACH IMPLANT IN BONE

On the potential of hydrated storage for naturally derived ECMs and associated effects on mechanical and cellular performance

Wall Shear Stresses Remain Elevated in Mature Arteriovenous Fistulas: A Case Study

Numerical modelling of Newtonian and non-Newtonian representation of blood in a distal end-to-side vascular bypass graft anastomosis

Demonstrating the Influence of Compression on Artery Wall Mass Transport

An evolutionary approach to wall shear stress prediction in a grafted artery

Mechanical, biological and structural characterization of in vitro ruptured human carotid plaque tissue

Experimental validation of convection-diffusion discretisation scheme employed for computational modelling of biological mass transport

Effects of flat, parabolic and realistic steady flow inlet profiles on idealised and realistic stent graft fits through Abdominal Aortic Aneurysms (AAA)

That hemodynamics and not material mismatch is of primary concern in bypass graft failure: An experimental argument

Wrist postures in the general population of computer users during a computer task

On reducing abnormal hemodynamics in the femoral end-to-side anastomosis: The influence of mechanical factors

Mechanical, biological and structural characterisation of in vitro ruptured human carotid plaque tissue.

Fluid-structure interaction of a patient-specific abdominal aortic aneurysm treated with an endovascular stent-graft

Improved assessment and treatment of abdominal aortic aneurysms: the use of 3D reconstructions as a surgical guidance tool in endovascular repair

3-D numerical simulation of blood flow through models of the human aorta

The Effects of Arterial Wall Remodelling on the Wall Shear Stress Distributions in Vascular Bypass Grafts ESEM Belfast May 3-5th 2001

On reducing hemodynamic factors in the femoral end-to side anastomosis: the influence of mechanical factors

Other Journals

Are we educating our students out of engineering?

Conference Publications

PROCEEDINGS OF THE ASME SUMMER BIOENGINEERING CONFERENCE 2008, PTS A AND B

IFMBE Proceedings

PROCEEDING OF THE ASME SUMMER BIOENGINEERING CONFERENCE - 2007

Proceedings of the ASME Summer Bioengineering Conference 2009, SBC2009

PROCEEDINGS OF THE ASME SUMMER BIOENGINEERING CONFERENCE - 2009, PT A AND B

IFMBE Proceedings

2007 AMERICAN CONTROL CONFERENCE, VOLS 1-13

Proceedings of the 5th World Congress of Biomechanics

The mesocolon a histological and electron microscopic characterisation of the mesenteric attachment of the colon prior to and after surgical mobilization.