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ULCaN Seminar Series

Fri, 05 Feb 2021

Date: Friday, February 5, 2021
Time: 1.00pm to 2:00pm
Contact: Justyna Lis -

Microsoft Teams meeting

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Presentation By

Speaker: Dr.Triona Ni Chonghaile

Royal College of Surgeons in Ireland

Presentation Title  

"Measuring and targeting sensitivity to cell death in cancer"


Dr. Ní Chonghaile’s lab is interested in understanding why certain cancers are sensitive to chemotherapy induced cell death while others are resistant and how best to treat resistant cancers. She has a particular interest in the BCL-2 family of proteins that regulate the mitochondrial cell death pathway. She uses an innovative technology called “BH3 profiling” to functionally interrogate the cell death signalling in both leukaemia and breast cancers to identify novel effective combinations of treatments

Speaker Profile 

Tríona Ní Chonghaile joined the Physiology and Medical Physics Department in the Royal College of Surgeons in Ireland, in 2015. She was recruited under the Strategic Academic Recruitment program (StAR), as a Research Lecturer. She completed her PhD in Biochemistry in 2008, with Prof. Afshin Samali, at the National University of Ireland, Galway. She had an interest in translational science and moved to the Dana-Farber Cancer Institute/Harvard Medical School to do a postdoc with Prof. Anthony Letai, which was funded in part by a Multiple Myeloma Research Foundation Fellowship. In 2014, she moved back to Ireland and joined Prof. William Gallagher’s group as a Research Fellow working on identifying novel therapeutics for triple negative breast cancer.