Professor Phil Jakeman

Qualifications: BSc Biochemistry, PhD Biochemistry/Endocrinology (University of Salford, UK); MSc Biochemistry (University of Manchester, UK)
Contact:

Email address  phil.jakeman@ul.ie
Phone number  +353 61 202800
Room number  P1042

Role:

Professor in Exericse Physiology

Teaching and Research Interests:

Teaching and research interests focus on the perturbation invoked by physical exercise as a vehicle to study the regulatory and adaptive processes of human metabolism in selected populations of human subjects. Founded on previous project grant funding from the Wellcome Trust (UK), the Leverhulme Trust (UK) and the Sir Jules Thorne Trust (UK) and recent funding from Enterprise Ireland, the Human Science Research Unit (HSRU) was formed in 2004 and is equipped to undertake metabolic studies in humans. Recent acquisitions include dual X-ray absorptiometry DXA and isotope-ratio mass spectrometry (combustible-IRMS). Recent collaboration with faculty from the new Medical School at UL are currently exploring the application of in-vivo microdialysis to human metabolic and exercise studies within the HSRU.
The Unit has project research base is housed within environment-controlled laboratories that can cater for;

  • Resting studies of human energy expenditure and exercise metabolism by indirect calorimetry and on-line metabolic measurement;
  • Exercise studies involving treadmill and/or cycle ergometry;
  • Human body composition by dual X-ray absorptiometry (DXA);
  • Human energy expenditure and metabolic studies of endogenous and exogenous substrate use using stable isotopes;
  • Invasive investigation via venous cannulation, skeletal muscle and adipose tissue percutaneous biopsy and in vivo microdialysis.

Personal Profile:

Philip Jakeman, graduated with an honours degree and research Masters Degree in Biochemistry from the University of Manchester, UK. A C.A.S.E. research scholarship in collaboration with I.C.I. (now Astra Zeneca) was followed by a PhD within the Human Performance Unit of the University of Salford which brought Dr Jakeman into exercise science as the biochemist attached to a multidisciplinary team supporting the physiological development of elite young athletes, including Sebastian Coe (now Lord Coe). Human endocrine and metabolic studies during exercise in normal and clinical populations, under the supervision of Dr Bruce Davies and Professor L.S. Bark, Vice-President of the Royal Society of Chemistry formed the basis of the PhD thesis. Dr. Jakeman remained in Manchester to pursue post-doctoral work funded by Nicolas International using radio-labelled drug diffusion techniques to optimise topical drug delivery through human skin before taking up a lectureship in Sport and Exercise Physiology at Manchester Metropolitan University (Crewe+Alsager Campus). Dr Jakeman's Applied Sports Science Support spanned the UK's Middle and Long Distance Athletes, England's Netball squad, Manchester City Football Club and selection of elite sprinters and rowers.
Appointed to the Department of Sport and Exercise Sciences, University of Birmingham in 1989, Dr Jakeman's collaborative work with the University's Clinical Research Unit (QEMC) under the direction of Professor Martin Kendal contributed to a strong research base (HEFC rated 5* in 1996) specialising in human metabolism, pharmacological/exercise interaction and the biochemistry of exercise. Appointment as Professor of Exercise Science in 1995, Dr Jakeman moved permanently to UL in 1996 as Head of the Department of Physical education and Sport Sciences with a responsibility to develop high quality teaching and scientific research in exercise science. Released from the duties of H.O.D. and with the benefit of a sabbatical term, Dr Jakeman formed the Human Science Research Unit (HSRU) in 2004 that now resides within a new suite of laboratories, to recommence his studies in exercise metabolism. A collaborative base of basic and clinical scientists in Ireland assists this new venture.
 

Selected Publications:

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Click here to view Educational Training & Professional Appointments.

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